Ramy H Bishay

Western NSW Local Health District · Endocrinology

Iron-induced hypophosphataemic osteomalacia remains under-recognized as a potential complication of parenteral iron therapy. We here report two cases of symptomatic hypophosphataemic osteomalacia with multiple insufficiency fractures in the context of chronic gastrointestinal blood loss, necessitating monthly iron polymaltose infusions over prolong...

The cost and comorbidity of obesity in hospitalized inpatients, is less known. A retrospective study of patients presenting to a large district hospital in Western Sydney (April 2016‐February 2017) using clinical, pathological as well as diagnostic coding data for obesity as per ICD‐10. Of 43 212 consecutive hospital presentations, 390 had an obesi...

Background Approximately two-thirds of individuals presenting to emergency departments in Western Sydney have glucose dysregulation, accelerating their risk of cardiovascular disease (CVD). We evaluated the prevalence and management of type 2 diabetes (T2D) in cardiology inpatients in Western Sydney. A novel model of care between diabetes and cardi...

Purpose Type 2 diabetes mellitus has become a major concern of Australian healthcare providers. From rates of barely more than 1 percent in the mid-90s, diabetes is now the leading cause of morbidity in the country. To combat the growing diabetes epidemic, Western Sydney Local Health District created the Western Sydney Diabetes (WSD) initiative. O...

We aimed to describe the current state of specialist obesity services for adults with clinically severe obesity in public hospitals in Australia, and to analyse the gap in resources based on expert consensus. We conducted two surveys to collect information about current and required specialist obesity services and resources using open‐ended questio...

INTRODUCTION Type 2 diabetes mellitus (T2DM) is a worldwide epidemic yet; self-empowerment remains an important yet under-utilised aspect of daily self-care in patients with T2DM. METHODS We retrospectively administered the validated Diabetes Empowerment Scale (DES) to evaluate self-empowerment in 42 obese, adult patients with T2DM who completed a...

Background: The global epidemic of obesity will see normal weight adults constituting a mere one-third of the global population by 2025. Although appetite and weight are regulated by a complex integration of neurological, endocrine and gastrointestinal feedback mechanisms, there is a constant interaction between psychological state, physical impai...

Maturity onset diabetes of the young (MODY), the most common monogenic form of diabetes, accounts for 1-2% of all diabetes diagnoses. Glucokinase (GCK)-MODY (also referred to as MODY2) constitutes 10-60% of all MODY cases and is inherited as an autosomal dominant heterozygous mutation, resulting in loss of function of the GCK gene. Patients with GC...

Autoimmune thyroid disease associated with interferon therapy can manifest as destructive thyroiditis, Graves’ Hyperthyroidism, and autoimmune (often subclinical) hypothyroidism, the latter persisting in many patients. There are scare reports of a single patient developing extremes of autoimmune thyroid disease activated by the immunomodulatory eff...

Background . Artifactual hypoglycaemia, defined as a discrepancy between glucometer (capillary) and plasma glucose levels, may lead to overtreatment and costly investigations. It is not infrequently observed in patients with Raynaud’s phenomenon due to vascular capillary distortion, yet this is clinically underappreciated. Case Report . We report a...

We report a 72-year-old female patient with diffuse large B cell non-Hodgkin's lymphoma (NHL) with previous treatment with standard chemotherapy presenting as an acute, ascending, sensorimotor polyneuropathy. Nerve conduction studies and lumbar puncture supported a rare, but ominous, axonal variant of Guillain-Barré Syndrome (GBS) known as acute mo...

Introduction: Obesity and diabetes are difficult to treat in public clinics. We sought to determine the effectiveness of the Metabolic Rehabilitation Program (MRP) in achieving long-term weight loss and improving glycaemic control versus "best practice" diabetes clinic (DC) in obese patients using a retrospective cohort study. Methods: Patients...

The global prevalence of people with a body mass index (BMI) over 30 kg/m 2 has doubled, over 40 kg/m 2 quadrupled, and over 50 kg/m 2 increased fivefold. 1-3 It is projected in Australia that if current rates of weight gain continue, normal-weight adults will constitute less than a third of the population by 2025, and the obesity prevalence will h...

Type 2 diabetes has become a worldwide epidemic, esti-mated to affect 1 in 14 adults, or 380 million people, globally by 2025. 1,2 The problem is particularly acute in Australia, where the preva-lence of diagnosed diabetes more than doubled between 1989 and 2005, amounting to 3 million people affected by the disease. 3,4 Diabetes is the most common...

The 'Mighty Mouse' Model in experimental cardiac transplantation Tissue rejection remains a major problem in organ transplantation. The use of experimental animal models continues to enhance our understanding of the rejection process and offers strategies for its prevention. The popular mouse model of heterotopic cardiac transplantation has been us...

Abstinence from meat and animal-based foods has been a long-held tradition of the three major world faiths. The myriad of Judeo-Christian traditions, particularly the writings of the Catholic-Orthodox Church Fathers still in extant, attests to the ubiquitous belief in this common form of observance during periods of fasting and penance. Aside from...

This study investigated the use of an ultrasound biomicroscope (UBM) to observe murine heterotopic cardiac transplants. By using an UBM (30 MHz), cardiac isografts in eight mice were studied on days 1, 5, 14 and 50 posttransplantation. The same method was tested in allografts in two mice on days 1, 5, 7 and 9. Two-dimensional imaging delineated the...

Cardiac transplantation is currently the preferred choice of treatment for end-stage cardiac disease. Despite great advances in controlling rejection and infection episodes, cardiac allograft vasculopathy (CAV) remains the leading cause of death after the first year of transplantation. CAV is an accelerated form of obliterative coronary artery dise...