Ramasundaram Thangaraj

• Ph.D.
• Professor (Assistant) at Periyar University

The growing demand for stricter environmental regulations surrounding waste disposal has sparked the development of advanced waste treatment techniques. This is crucial because the consumption of contaminated water can lead to the transmission of life-threatening diseases, resulting in millions of deaths worldwide each year. One promising approach...

This present study deals with the synthesis of gelatin-loaded zinc oxide nanocomposites (GN/ZnONCs) using Coccinia indica seed extract using the green preparative method. Synthesized GN/ZnONCs were confirmed by using various characterization techniques for chemical and physical properties. The results of the UV–Vis spectral absorption peak showed 2...

Soil and earthworms are threatened by anthropogenic contamination resulting from olive mill waste dumping on the soil due to their pollutant properties. While several studies have explored the effects of olive mill waste on soil properties and the accumulation of heavy metals in soil, there is currently a gap in the literature regarding the potenti...

This present study deals with the synthesis of gelatin-loaded zinc oxide nanocomposites (GN/ZnONCs) using Coccinia indica seed extract using the green preparative method. Synthesized GN/ZnONCs were confirmed by using various characterization techniques for chemical and physical properties. The results of the UV-Vis spectral absorption peak showed 1...

Alzheimer's disease (AD) is a neurodegenerative disease characterized by amyloid-beta (Aβ) aggregation, neuroinflammation, oxidative stress, and dysfunction in the mitochondria and cholinergic system. In this study, the synthesis of chitosan-polylactic acid-loaded magnesium oxide nanocomposite (CH/PLA/MgONCs) was examined using the green precipitat...

Non-healing wounds are a serious complication of bacterial infections, and finding effective treatments is crucial. The novelty of the current study is the synthesis and characterization of gelatin-loaded magnesium hydroxide nanocomposite using an extract from Coleus amboinicus leaves. Investigations presented that the Ge/Mg(OH)2NCs exhibited highe...

Alzheimer's disease (AD) is a neurodegenerative disease characterized by amyloid-beta (Aβ) aggregation, neuroinflammation, oxidative stress, and dysfunction in the mitochondria and cholinergic system. In this study, the synthesis of chitosan-polylactic acid-loaded magnesium oxide nanocomposite (CH/PLA/MgONCs) was examined using the green precipitat...

Alzheimer’s disease (AD) is an age-dependent neurodegenerative disease hallmarked by Amyloid-β (Aβ) aggregation, cognitive impairment, and neuronal and synaptic loss. In this study, AD was induced in male Wistar rats (n = 6) by the administration of intracerebroventricular-streptozotocin (ICV-STZ-3 mg/kg/day), and Voglibose (Vog) was administered a...

Amyloid-β (Aβ) plaque formation, neuronal cell death, mitochondrial and cholinergic dysfunction are key indicators of Alzheimer's disease (AD). In this study, gelatin and polyvinyl alcohol (PVA) were tethered with magnesium hydroxide (Mg(OH)2) to synthesize nanocomposite (Ge/PVA/Mg(OH)2) through alkali co-precipitation. The characterization studies...

Amyloid-β (Aβ) plaque formation, neuronal cell death, and cognitive impairment are the unique symptoms of Alzheimer's disease (AD). No single step remedy is available to treat AD, so the present study aimed to improve the drugability and minimize the abnormal behavioral and biochemical activities in streptozotocin (STZ) induced AD experimental Wist...

Engine oil consists of hazardous substances that adversely affect the environment and soil quality. Bioremedi-ation (employing organisms) is an appropriate technique to mitigate engine oil pollution. In the present study, the earthworm species, Drawida modesta (epigeic) and Lampito mauritii (anecic) were used to restore the soil polluted with polyc...

The development of multifunctional nanocomposite can greatly improve therapeutic effects to impair tumor proliferation. In the present study, we developed a new class of dual-drug delivering system, the Selenium Mesoporous Silica (SMS) nanocomposites to achieve molecular based tumor-targeting. A series of experiments have been performed to tether M...

An enormous amount of chicken feather waste materials released by the poultry industry creates severe environmental pollution. Vermicomposting is an eco-friendly way to degrade chicken feather waste along with microbial mixture (Panchagavya). Chicken feather waste was pre-decomposed by mixing it with fresh cow dung (T1), dry cow dung (T2), and Panc...

The industrial revolution and indiscriminate usage of a wide spectrum of agrochemicals account for the dumping of heavy metals in the environment. In-situ/ex-situ physicochemical, and bioremediation strategies with pros and cons have been adopted for recovering metal contaminated soils and water. Therefore, there is an urgent requirement for a cost...

Earthworms are known to reclaim soil contamination and maintain soil health. In the present study, the concentration of DTPA extractable heavy metals, Cd, Cu, Cr, Pb, and Zn in vermicasts and tissues of the earthworms (anecic: Lampito mauritii; epigeic: Drawida sulcata) collected from the soils of four different industrial sites, Site-I (Sago indus...

The invasive weed, Ipomoea staphylina (IS) with cow dung (CD) and mushroom spent straw (MS) in four different combinations (IS:CD:MS), V1 (1:1:0), V2 (2:1:1), V3 (1:0:1) and V4 (1:1:1) were pre-decomposed for 21 days followed by 50 days vermicomposting using Eudrilus eugeniae in triplicates in order to alleviate and to utilize the weed biomass in a...

The current review reports the importance and significance of cattle solid waste in vermicomposting technology concerning biowaste pollution in the environment. Needy increasing population evokes livestock production resulting in the massive generation of livestock wastes, especially cattle dung. Improper disposal and handling of biowastes originat...

h i g h l i g h t s g r a p h i c a l a b s t r a c t A significant amount of heavy metals were bioaccumulated in epigeic earthworms. Vermicasts contain permissible limits of heavy metals. Humic substances stimulate the ion exchange process in heavy metals. Metallothionein attracts heavy metal ions and triggers the detoxification process. a b s t r...

Chitosan (CS) is one of the most abundant biopolymers present on the wings of arthropod members like insects, prawns, etc. It has potential biomedical value in developing drugs and drug delivery systems. Such a biomedically valuable polymer was combined with mesoporous silica nanoparticles (MSNs) to form chitosan-poly (acrylic acid) coated mesoporo...

Vermicomposting of pressmud with cow dung and nitrogenous green manures (Gliricidia sepium and Leucaena leucocephala) was carried out using Eudrilus eugeniae (50 days). The reduction in pH, total organic carbon, C/N ratio, water-soluble organic carbon (Cws)/Norg and C/P ratios, and a pronounced increase in NPK contents and microbial population in v...

Earthworms are an ideal biological model in toxicity assays and environmental monitoring studies. In the present study, the reproductive toxicity and histopathological effects of Monocrotophos pesticide on an exotic epigeic Eudrilus eugeniae and an indigenous epigeic Perionyx barotensis earthworm were studied. Earthworm species were exposed to diff...

Poultry litter contains an enormous amount of nutrients that create environmental problems like eutrophication and phytotoxicity. These challenges can be mitigated by stabilizing its nutrients using earthworms. The objective of the present study was to decompose poultry litter amended with cow dung and Tectona grandis leaf litter into vermicompost...

The present study demonstrates the vermistabilization of paper mill wastewater sludge (PMS) spiked with cow dung (CD) employing indigenous epigeic earthworm Perionyx excavatus Perrier. A total of six treatments were prepared along with a positive control (PC) and negative control (NC). Twenty earthworms were released into each treatment including P...

Currently, in clinics, breast cancer is treated with free chemotherapeutic drugs, as a result there is not much therapeutic effect in treated models, leading to substantial systemic toxicity. To overcome these critical problems for the primary outcome, we developed the formulated nanomaterial (FA-PEG@BBR-AgNPs) aimed to specifically target cancer c...

Development of nano-drug cum nano-carrier in a single platform seems to be conquered by almost are missionary fanaticism towards unraveling more and more about their bioavailability and anticancer activity at the molecular level. The present work is mainly focusing on bioformulation of silver nanoparticles (AgNPs) as a carrier for Berberine (BBR) a...

Background & Objectives: Dermatophytes are fungi that can cause infections in keratin tissue constitute a serious problem, especially in tropical and subtropical countries. Antimicrobials of plant origin are effective in the treatment of infectious diseases while simultaneously mitigating many side effects that are often associated with synthetic a...

The aqueous and ethanolic extracts of Acorus calamus was evaluated for antibacterial activity against clinically important bacteria viz.. Bacillus subtilis (MTCC 441), Staphylococcus aureus (MTCC 96), Escherichia coli (MTCC 443), Proteus mirabilis (MTCC 1429), Pseudomonas aeruginosa (MTCC 424). The in-vitro antibacterial activity was performed by a...

Background & Objectives: Phytochemicals are the plant-derived naturally occurring compounds showed antimicrobial activity. The lack of data on antibacterial activity of Heliotropium indicum makes this study useful. Methods: In the present study phytochemical estimation (phenolics, flavonoids and carotenoids) and antibacterial activity of aqueous an...

Mycorrhizal association in Sugarcane (Saccharum officinarum) grown in four different areas of South India was recorded. Observation on physico-chemical properties of rhizosphere soils, arbuscular mycorrhizal (AM) fungal spore count and root colonization were recorded. AM spores isolated were of Acaulospora scrobiculata,Gigaspora margarita, Glomus a...

Stress is one of the basic factors in the etiology of number of diseases. Cold-stress occurs when the surrounding temperature drops below 18 degrees C, the body may not be able to warm itself, and hence serious cold-related illnesses, permanent tissue damage and death may results. The present study was aimed to investigate the effect of Triphala (T...

The present study was aimed to investigate the antioxidant property of Emblica officinalis (E. offic- inalis) during restrain-stress in albino rat. Three groups of albino rat were employed namely control, restrain-stress (4hr/day for 15days) and E. officinalis +r estrain-stress. The oxidative stress was assessed by measuring the lipid peroxidation...

The isolation of microbial agents less susceptible to regular antibiotics and the rising trend in the recovery rates of resistant bacteria highlights the need for newer alternative principles. Triphala has been used in traditional medicine practice against certain diseases such as jaundice, fever, cough, eye diseases etc. In the present study phyto...