
Raman NatarajanVirudhunagar Hindu Nadars' Senthikumara Nadar College | VHNSN College · Department of Chemistry
Raman Natarajan
Ph.D.,
DNA interaction studies with metal complexes
About
242
Publications
49,174
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
6,762
Citations
Introduction
Raman Natarajan currently works at the Department of Chemistry, Virudhunagar Hindu Nadars' Senthikumara Nadar College. Raman does research in Bio-inorganic Chemistry, Chemical Biology and Biochemistry. Their current project is '“Synthesize of Antitumor active Pyrimidine Derivative Ligands and its Cu, Zn, Pt and Au Complexes”'.
Publications
Publications (242)
In the current study, Knoevenagel condensates mediated by ultrasound were created using cinnamaldehyde and physiologically active curcumin. These Knoevenagel condensates have been reacted with 4‐aminoantipyrene to create curcumin Schiff bases. The octahedral geometry of the synthesized transition metal complexes is verified by a range of analytical...
Oxidovanadium meso‐tetrakis(3,4,5‐trimethoxyphenyl) porphyrin [VO(T(OMe)3PP)] (Complex 1) was prepared. The oxidation product of Complex 1 has been characterized by cyclic voltammetry (CV), UV–visible spectrophotometer, electron paramagnetic resonance (EPR) and nuclear magnetic resonance (NMR) by the addition of SbCl5 to Complex 1. There is a one‐e...
In this article, a Schiff base derivative has been prepared using 2‐hydroxy‐1,4‐naphthoquinone and 3‐amino‐1,2,4‐triazole, and consecutively, four metal complexes (Co(II), Ni(II), Cu(II) and Zn(II)) have been synthesized using this Schiff base derivative as precursor ligand. Characterization of the synthesized compounds are done by employing spectr...
To obtain the highest level of biological effectiveness, four transition metal viz., Cu(II), Zn(II), Co(II) and Ni(II) complexes viz. were synthesized using Schiff base obtained by the condensation reaction of o-phenylene diamine, 4-chlorobenzaldehyde and a co-ligand (malonic acid). Elemental analysis and other spectroscopic methods were used to id...
Herein, novel Cu(II) and Zn(II) complexes of the type [ML(dppz)]Cl2 were created and characterised using a variety of analytical and spectral techniques where L = Schiff bases created by the condensation of (E)-3-(2-mercaptovinyl)-pentane-2,4-dione and para-substituted anilines(X= -NO2,-Cl, and –Br) i.e (E)-4-((4-nitrophenyl)imino)-3-((E)-1-((4-nit...
Several transition metal complexes [ML(phth)], where M = Cu(II), Zn(II), Co(II) and Ni(II), X = phthalic acid and L = Schiff base generated from benzene-1,2,diamine and 4-chlorobenzaldehyde, were synthesized and characterized by IR, UV-Vis, 1H NMR, 13C NMR and mass spectra. According to the physico-chemical studies, all the synthesized metal(II) co...
Researchers have renewed interest in naturally occurring compounds and their applications particularly in the pharmacological field with the goal of fewer side effects; lawsone is one among them. It is easily available and cost-efficient among the naphthoquinone family. Lawsone and its metal complexes are compounds with a wide variety of applicatio...
This work focuses on the electrochemical sensing of Flutamide (FLA) drug using a ternary composite material namely reduced graphene oxide (rGO) wrapped with bismuth vanadate (BiVO4) loaded on chemically exfoliated boron nitride (CE-BN). To synthesize this material, BiVO4 was prepared using the solvothermal method; secondly, graphene oxide was prepa...
Porphyrin is an organic molecule with the properties of protracted electronic structure with π-conjugation, extreme molar absorption to near-infrared spectrum from the visible region, supreme oxygen quantum yields with singlet state, and chemical flexibility. The nanoparticles of porphyrin and its derivatives have been developed for drug delivery s...
A novel binary heterogeneous electrocatalyst, Co2SnO4, decorated on chemically exfoliated boron nitride sheets (CE-BN) with an exceptional capacity to detect electrochemical properties has been prepared by the simple hydrothermal method. The structural, surface morphology and electrochemical characteristics of Co2SnO4/CE-BN were characterized using...
In this study, catalytic-degradation of dyes such as methylene blue (MB) and malachite green (MG) was carried out by using silver nanoparticles (AgNPs), obtained by adopting the flower extract of Luffa acutangula (LA). The biogenic synthesised LA-AgNPs were characterised by using UV-Vis spectroscopy, Fourier-transform infrared spectroscopy (FTIR),...
A green approach for the biosynthesis of silver nanoparticles (AgNPs) was developed using Heterotheca subaxillaris and their catalytic degradation efficiency of Methyl orange (MO) dye was explored. The formation of HS-AgNPs was monitored using UV-vis spectroscopy. The HR-TEM analysis confirmed quasi-spherical shape with the average particle size ra...
A novel metal stannate (Mn2SnO4) nanocube electrocatalyst with an outstanding sensing capability of electrochemical property is established by ultrasonic-assisted technique. A variety of physicochemical and electrochemical methods were used to...
The present work describes the synthesis of a few novel Knoevenagel condensed copper(II) complexes from Schiff bases of thiosemicarbazide derivatives. The synthesized compounds have been characterized by various analytical and spectral techniques. The DFT calculations were carried on these compounds using Gaussian 09W software which theoretically c...
A few novelmetallonucleases were synthesized from curcumin derived Schiff base incorporating 2-aminobenzothiazoleand o-phenylenediamine. By characterization, these complexes were found to have 1:1:1 stoichiometry [M:L:o-Ph]. They were inferred to be electrolytic in nature in accordance to the values of molar conductance. From the spectral data the...
A novel electrochemical sensor based on Bi2Sn2O7 modified glassy carbon electrode (GCE) has been successfully developed for the determination of nitroxoline (NXT). The Bi2Sn2O7 is synthesized using a hydrothermal method, and its physicochemical properties are characterized by SEM, HR-TEM, EDX, elemental mapping, FT-IR and XRD, to identify structura...
The present work described a simple, green, and fast approach for the synthesis of silver nanoparticles using an aqueous fruit extract of Alstonia scholaris(AS-AgNPs). The role of plant extract was identified as both reducing as well as capping agent in the synthesis of AS-AgNPs. The formation of AS-AgNPs was confirmed through the visible color cha...
This article focuses on the combination of Cu(II) and Zn(II) ions with sulfur derivatives having Knoevenagel condensate β-diketimines and their pharmacological evaluation. Characterization of these complexes was done by usual spectroscopic and analytical techniques. The observed data demonstrate that the complexes have 1:1 (metal:Schiff base deriva...
Mixed-ligand complexes of bivalent metal ions, viz, Co(II), Ni(II), Cu(II), and Zn(II) of the composition [ML(dan)]Cl (where L = Schiff base ligand, dan = 1,8-diaminonaphthalene and M = Co(II), Ni(II), Cu(II), Zn(II)) have been synthesized and characterized. The stoichiometric ratio of the prepared complexes has been estimated using complementary t...
Complexes are currently synthesized from plant origin because of their therapeutic effect against certain diseases with toxicity. Hence, in this work, four new transition metal(II) mixed ligand complexes have been synthesized using a curcumin Schiff base (primary ligand) and lawsone (as co-ligand). The geometry of these complexes was explored by el...
Novel macrocyclic Schiff base complexes [[ML]X; where M = Cu(II), Co(II), Ni(II), Zn(II), Mn(II) and VO(IV); L = macrocyclic ligand; X = Cl2 and SO42-] have been synthesized and characterized by microanalytical, 1H, 13C NMR, IR, Mass, UV-Vis, EPR spectral studies, as well as conductivity data. All the complexes exhibit square-planar geometry except...
Metal complexes have more biological activities than their corresponding ligands. In particular, Schiff base complexes are of great interest due to their stability, electron donating ability, catalytic, photochromic, optical nonlinearity properties and biological activities. These are all based on the coordination of Schiff bases to metal ions. Ami...
A novel electrochemical sensor, based on Co2SnO4 (CoSnO) modified glassy carbon electrode (GCE) has been successfully developed for the determination of 2-nitroaniline (2-NA). The CoSnO was synthesized by a simple co-precipitation method and characterized by FE-SEM, HR-TEM, EDX, FT-IR and XRD. The CoSnO modified GCE was investigated towards the ele...
The undesirable effects caused by the chemotherapeutic drugs are already in use, mainly the platinated compounds requiring amendments for which many potential scaffolds resembling the activity of cisplatin are explored. Herein, the DNA binding, cleavage, molecular docking, antimicrobial proficiency, and cytotoxic nature of four non-platinated trans...
A series of hetero ligand MLB complexes (1–5) were synthesised from tridentate NO2 type Schiff base [H2L: (E)-2-((2-hydroxy-4-methoxyphenyl)(phenyl)methyleneamino)benzoic acid; derived from 2-hydroxy-4-methoxybenzophenone and 2-aminobenzoic acid] and bidentate N2 type 1,10-phenanthroline (B: phen) ligands. The structural characterization of the syn...
A novel tryptophan-derived Schiff base ligand (potassium (E)-2-((4-chloro-3-nitrobenzylidene)amino)-3-(1H-indol-3-yl)propanoate) and a series of its transition metal complexes of the types [ML2] and [ML(1,10-phen)2]Cl where M = Cu(II), Co(II), Ni(II) and Zn(II) were prepared. They were analyzed by various spectral and physicochemical studies. The X...
In this work, we have synthesized a few novel mononuclear complexes of Cu(II), Co(II), Ni(II) and Zn(II) using a pyrazolone-derived Schiff base ligand. They were characterized by spectroscopic and analytical methods. The elemental analyses, UV-Vis, magnetic moment values and molar conductance of the complexes reveal that the complexes adopt an octa...
A series of transition metal complexes have been synthesized from biologically active curcumin and isoniazid Schiff base. They are characterized by various spectral techniques like UV-Vis, FT-IR, NMR, EPR and Mass spectroscopy. Moreover, elemental analysis, magnetic susceptibility, and molar conductivity measurements are also carried out. All these...
This work deals with a series of biologically important novel transition metal(II) Schiff base chelates containing terpyridine. Benzimidazole, a moiety found in broad spectrum of drugs is espoused in a Schiff base ligand system. Eight such metal(II) complexes are designed, synthesized and characterized. An octahedral geometry has been envisaged for...
Four novel tryptophan based metal (II) complexes of the type [ML (Try)2] were prepared by using pyrazolone derived Schiff base ligand. The proposed structure was confirmed by physicochemical methods which reveal octahedral coordination environment around the metal center. Intercalative binding mode of the complexes with CT DNA was confirmed by elec...
Two triazole-derived Schiff base ligands and their eight octahedral metal(II) complexes were designed and synthesized. They were characterized by elemental analysis and various spectroscopic techniques. The compounds were evaluated for their DNA binding tendencies with Calf thymus DNA. The concentration dependent chemical nuclease activity was also...
Four new metal complexes were synthesized and screened for their cytotoxic activity after sufficient assertion from the preliminary DNA binding studies. The metal complexes could bind to CT-DNA through intercalation binding mode. This has also been confirmed by the molecular docking studies. The DNA cleavage efficiencies of these complexes with pBR...
A novel series of histidine derived transition metal complexes were synthesized and characterized by multispectral techniques such as UV-Vis., FT IR, EPR, NMR, ESI-mass analysis and other physico-chemical methods like elemental analysis, molar conductivity, magnetic susceptibility. The synthesized compounds were attempted for their biological prosp...
A heterocyclic compound, 2-(aminomethyl)benzimidazole dihydrohydrochloride, was treated with nitrobenzaldehyde to form a Schiff base that was made to react with divalent metals. A co-ligand, either 1,10-phenanthroline or 2,2′-bipyridine, was added to this mixture to obtain metal chelators of type [ML(co-L)2]Cl2. They were in 1:1:2 stoichiometry rat...
Triazole appended mixed ligand complexes (1-8) of the general formula [ML(bpy/phen)2]Cl2, where M= Cu(II), Co(II), Ni(II) and Zn(II), L= triazole appended Schiff base (E)-N-(4-nitrobenzylidene)-1H-1,2,4-triazol-3-amine and bpy/phen = 2,2′-bipyridine/1,10-phenanthroline, have been synthesized. The design and synthesis of this elaborate ligand has be...
Flavonoids are a group of plant phenolics that provide various health benefits through cell signalling pathways and antioxidant effects. In the present study, a new series of mixed ligand complexes of Co(II), Ni(II), Cu(II) and Zn(II) were synthesized by incorporating curcumin and quercetin flavonoid precursors. The structural features of the synth...
An unique Schiff base ligand, formed by the condensation reaction of 2-aminobenzothiazole with curcumin and its Cu(II), Ni(II), Co(II) and Zn(II) complexes incorporating 2,2′-bipyridine as coligand were synthesised. They were characterized via analytical and spectroscopic methods. The complexes adopt square planar geometry. Their antimicrobial acti...
In the present study, a new series of novel mixed ligand metal complexes with the composition of [ML(His)]Cl [where M = Cu(II), Co(II), Ni(II), and Zn(II); L = (E)-4-((4-chloro-3-nitrobenzylidine)amino)-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one; His = L-histidine] have been synthesized and characterized by diverse spectral techniques such as eleme...
Two novel oxovanadium(IV) complexes [VOL1]SO4(1) and [VOL2]SO4(2) containing Knoevenagel condensate Schiff base ligand (L1/L2) have been synthesized and characterized by physical, spectral and analytical methods. These complexes are reported as ionic in nature on the basis of elemental composition and molar conductance, and possess square pyramidal...
Tridentate Schiff base (L) has been synthesized by condensation of salicylaldehyde and p- aminoacetanilide in ethanol and treating with copper, nickel, cobalt and zinc chlorides form
metal complexes. The synthesized compounds are characterized by analytical and spectral
methods. The results indicate that the complexes are having ML2 the composition...
A new bioessential Knoevenagel condensate Schiff base ligand (L) was synthesized by the reaction of 3-(4-hydroxy-3-methoxybenzyl)pentane-2,4-dione and 4-aminoantipyrine. The ligand forms monomeric divalent transition metal complexes (1–4) which were characterized using spectral and analytical data. All these complexes have the general formula [ML]C...
Reliable compounds with low toxicity are tempting potential chemotherapeutics. With an aim of achieving less toxic but more potent metallodrugs, four new-generation hydrophilic Cu(II) and Zn(II) complexes with DNA-targeting properties were synthesized and characterized using various physicochemical data. The excellent DNA binding and cleavage resul...
Few N4O2 type mixed ligand complexes (metallointercalators) were synthesized using benzene-1,2-diamine derived Schiff base as primary ligand and 8-hydroxyquinoline as co-ligand. They were characterized by physico-chemical and spectral techniques. The binding properties with DNA explored by different techniques indicate that the complexes have the a...
Amidst the very many metallodrugs for the treatment of cancer regularly reported, the development of the next generation of compounds with an aim of overcoming the shortcomings by enhancing biological activity and cytotoxicity but exhibiting low toxicity is essential. Herein we report such octahedral metal(II) complexes (1–12) containing triazole-d...
Four new transition metal complexes incorporating a Schiff base ligand derived from propylenediamine and 4-formyl-N,N-dimethylaniline have been synthesized using transition metal salts. The characterization of the newly formed complexes was done from physicochemical parameters and using various techniques like 1H NMR, 13C NMR, IR, UV, electron para...
A series of novel Co(II), Cu(II), Ni(II) and Zn(II) complexes (1–8) were synthesized from pyrazolone precursor Schiff base(s), obtained by the condensation of 4-amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one (4–aminoantipyrine) with cinnamaldehyde/benzaldehyde and respective metal(II) chloride. They have been characterized by elemental analysis, mag...
Eight transition metal complexes were designed to achieve maximum biological efficacy. They were characterized by elemental analysis and various other spectroscopic techniques. The monomeric complexes were found to espouse octahedral geometry and non-electrolytic nature. The DNA interaction propensity of the complexes with calf thymus DNA (CT-DNA),...
Few novel transition metal complexes having N-((2-aminophenyl)(phenyl)methylene)-4-nitroaniline were synthesized and characterized by elemental analyses, IR, 1H and 13C NMR, electronic, EPR and mass spectra, conductivity and magnetic susceptibility measurements. All the metal complexes adopted square planar geometrical arrangements. The DNA-binding...
This paper describes the synthesis of four novel bidentate metal(II) complexes having 2-aminobenzophenone precursor and a co-ligand (anthranilic acid). They are characterized by the usual spectral and analytical data. They adopt octahedral geometrical arrangements around the metal ions which have been confirmed by electronic absorption data. Moreov...
A series of Cu(II), Co(II), Zn(II) and Ni(II) mixed ligand metal complexes have been synthesized using the Schiff base ligand (L1), derived from the condensation reaction of 4-amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one (4-aminoantipyrine) with 3-phenyl-prop-2-enal (cinnamaldehyde) and Knoevenagel condensate ligand (L2), derived from pentane-2,4-...
The physiological and pharmacological applications of imidazole and its derivatives have attracted the researchers and are being explored since a decade. Based on its promising features, few imidazole based Cu(II), Co(II), Ni(II) and Zn(II) complexes have been synthesized. The chemical structures were elucidated by IR, NMR, EPR and UV-vis. spectral...
A few novel Schiff base transition metal complexes of general formula [MLCl] (where, L = Schiff base, obtained by the condensation reaction of Knoevenagel condensate of curcumin, l-tryptophan and M = Cu(II), Ni(II), Co(II), and Zn(II)), were prepared by stencil synthesis. They were typified using UV–vis, IR, EPR spectral techniques, micro analytica...
A novel tetradentate N2O2 type of Knoevenagel condensate Schiff base, synthesized from 4-amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one (4-aminoantipyrine) and 3-(cinnamyl)-pentane-2,4-dione, forms stable complexes with transition metal ions such as Cu(II), Co(II), Ni(II) and Zn(II). The structural features were derived from elemental analysis, mola...
A new series of cysteine-based metal(II) complexes with 2,2'-bipyridine or 1,10-phenanthroline as co-ligand have been prepared and characterized. Their DNA binding and cleavage properties have been studied. The analytical and spectroscopic data of complexes 1-18 reveal that the complexes adopt an octahedral geometry around the central metal ion in...
Schiff bases have been exposed to reveal a wide range of biological activities, including antifungal, antibacterial, antimalarial, anti-proliferative, anti-inflammatory, antiviral, and antipyretic properties. Mixed ligand complexes can be a synthetic challenge to tune the properties of the transition metal complexes. The review of this paper covers...
Transition metals have an important place within medicinal inorganic chemistry. Transition metals exhibit different
oxidation states and can interact with a number of negatively charged molecules. This activity of transition metals
led to the recent development of drugs which are based on metals and are considered to be potential candidates
for pha...
Few imidazole based Cu(II), Zn(II), Ni(II) and Co(II) complexes have been synthesized and characterized by UV-Vis., IR, NMR, EPR and Mass spectral data. The molar conductivity of the metal complexes, dissolved in DMF (10-3 M) at room temperature, reveal that all the complexes are electrolytic in nature. The electronic absorption spectral data exhib...
New series of bio-essential metal based complexes linked by Schiff base ligand (L) and 2,2'-bipyridine (bpy) have been synthesized and characterized by diverse spectral techniques such as elemental analysis, magnetic susceptibility, molar conductivity measurements, FT-IR, UV-Vis., (1)H NMR, (13)C NMR, EPR and Mass. The spectral data suggest that th...
In the present work, we attempted to develop new metal complexes (Cu(II), Co(II), Ni(II) and Zn(II)) of the imine ligand which was synthesized from 9,10-phenanthrenequinone and para-anisidine. With an intention to make the complexes most stable, very special chelating amino acid has been coordinated to the metal centre. The resultant metal complexe...
The coordination of therapeutically interesting designed complexes of stoichiometry [ML(Met)Cl2] [where M=Cu(II), Co(II), Ni(II), Mn(II) and Zn(II), L=benzylidene-4-aminoantipyrine and Met=methionine] has been ascertained on the basis of physicochemical techniques. Their interaction with CT DNA reveals that they are good intercalators. The anticanc...
A new series of metal(II) complexes using a symmetric Schiff base ligand, obtained by the condensation reaction of 4-formyl-N,N-dimethylaniline with benzene-1,2-diamine were synthesized and characterized. The various physico-chemical data indicate that the complexes have octahedral geometry. The intrinsic binding constant of the complexes with DNA...
The present contribution reports a thorough characterization of newly obtained metallointercalators incorporating Schiff bases, formed by the condensation of N-acetoacetyl-o-toluidine with 1-amino-4-nitrobenzene (L(1))/1-amino-4-chlorobenzene (L(2)) as main ligand and 1,10-phenanthroline as co-ligand respectively. The characterization of newly form...
Pyrazolone incorporating N-acetylcysteine (NAC) mixed-ligand complexes are described as promising anti-inflammatory, anticonvulsant, SODs mimetic and cytotoxic compounds possibly due to its antioxidant profile. In this study, we have evaluated the pharmacologic activity, antioxidant and toxicological profiles of compounds (1-6). Among them, compoun...
A series of novel mixed-ligand complexes of Cu(II), Zn(II), Co(II) and Ni(II) have been prepared in order to appraise the consequence of metal ions upon chelation using the ligands, obtained by the condensation reaction of N-acetoacetyl-o-toluidine with 4-aminophenol (main ligand) and 1,10-phenanthroline (co-ligand). The characterization of newly f...
The DNA interaction efficacies of mixed-ligand complexes [ML(phen)2]Cl [L = a Schiff base derived from p-substituted benzaldehyde (L1 = NO2/L2 = –OCH3) and methionine; phen = 1,10-phenanthroline, the co-ligand] have been explored by absorption, electrochemistry, viscosity measurements, and agarose gel electrophoresis. The results indicate that thes...
New metallointercalators (1a–1e) have been synthesized using the Schiff base, 4-[phenyl(phenylimino)methyl]benzene-1,3-diol and metal(II) ions, viz. Mn(II), Co(II), Ni(II), Cu(II), and Zn(II). They are characterized by analytical and spectral methods. Elemental analyses and molar conductance values reveal that the Schiff base metal(II) complexes ha...
Single phase CoS2 nanoparticles are prepared by thermal decomposition of the cobalt—(H2N)2C=S (tu) complex [Co(tu)4(NO3)2] at 400 °C.
Four new Cu(II), Ni(II), Co(II) and Zn(II) metalloinsertors have been synthesized by using a Schiff base, formed by the condensation reaction of 4-formyl-N,N-dimethylaniline with o-phenylenediamine. They have been structurally characterized by IR, NMR, UV-vis, EPR, elemental analyses, magnetic susceptibility and molar conductivity studies. The mola...
This work presents the synthesis and characterization of four new metal(II) complexes of 9,10-phenanthrenequinone based Schiff base precursor. From UV–vis, FT-IR, 1H NMR, EPR and Raman spectral data, an octahedral geometry has been assigned to the complexes. The molar conductivity and magnetic moment measurements indicate the non-electrolytic and m...
Few novel Cu(II) and Zn(II) oxali-platin type complexes of stoichiometry [ML(ox)] where, L is a Knoevenagel
ligand and ox is oxalic acid, have been explored. They are well characterized by spectroanalytical
methods. The binding and cleavage propensity of these complexes on DNA and their cytotoxic effect in
tumor cells have been investigated. They b...
The 4-aminoantipyrine derivatives (-NO2, -OCH3) and their mixed-ligand complexes with amino acids have been synthesized and investigated for their binding with CT DNA using UV-visible spectroscopy, cyclic voltammetry, and viscosity measurements under physiological conditions of pH (stomach 4.7; blood 7.4). The results from all techniques i.e. bindi...
This work focuses the synthesis and characterization of few novel mixed ligand Schiff base metal complexes and their biological activities. For deriving the structural aspects, spectral techniques such as FT-IR, UV-Vis., H-1 NMR, Raman, EPR and the physicochemical characterizations including elemental analysis, molar conductance and magnetic suscep...
Few curcumin based metallointercalators having the amino add (cysteine) have been synthesized and characterized by IR, UV-vis, NMR, EPR and magnetic susceptibility measurements. The data show that the complexes have the composition of ML type. The electronic absorption spectral data of the complexes suggest a square planar geometry around the centr...
A new bidentate NO type Schiff base ligand (HL), derived from 2–hydroxy–4–methoxyphenyl)phenylmethanone with aniline and its metal(II) [M = Mn, Co, Ni, Cu and Zn] complexes have been synthesized. The synthesized ligand and the metal(II) complexes were structurally characterized by analytical, spectral (FT–IR, UV–vis., 1H NMR, FAB–Mass, TGA/DTA and...
Present work reports the DNA binding and cleavage characteristics of a series of mixed-ligand complexes having the composition [M(L)(phen)2]Cl2 (where M=Cu(II), Ni(II), Co(II) and Zn(II) and phen as co-ligand) in detail. Their structural features and other properties have been deduced from their elemental analyses, magnetic susceptibility and molar...
Few novel Cu(II) and Zn(II) oxali-platin type complexes of stoichiometry [ML(ox)] where, L is a Knoevenagel ligand and ox is oxalic acid, have been explored. They are well characterized by spectroanalytical methods. The binding and cleavage propensity of these complexes on DNA and their cytotoxic effect in tumor cells have been investigated. They b...
Single phase cobalt disulfide (CoS2) nanoparticles were prepared by thermal decomposition of cobalt-thiourea complex at a low temperature (400 °C). CoS2 nanoparticles exhibit ferromagnetic ordering at 122 K below which the temperature dependent resistivity of cold pressed nanoparticles deviates from metallic behavior and shows a broad maximum. Just...
Few novel 2-aminobenzophenone based Co(II), Ni(II), Cu(II) and Zn(II) Schiff base complexes were synthesized. They were characterized by elemental analysis, molar conductance, magnetic measurement, FT-IR, UV-Vis., 1H-NMR, and EPR. The conductance data indicates that all the complexes are non-electrolytes. FT-IR results demonstrate that the Schiff b...