Raja Chakraverty

Raja Chakraverty
National Institute of Cholera and Enteric Diseases

ICMR Scientist C with 8 years of teaching and research experience
Selected as Scientist at AIIMS, New Delhi Email: rchakraborty20@yahoo.com

About

45
Publications
32,552
Reads
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95
Citations
Introduction
M Pharm, (Ph.D) in Pharmacology with nine years of teaching and research experience. Peer reviewer and an author. ORCID ID: 0000-0002-7193-3604
Additional affiliations
October 2018 - present
Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital
Position
  • Fellow
Description
  • Antibiotic stewardship
March 2016 - October 2018
Bengal School of Technology (BST)
Position
  • Professor (Assistant)
September 2013 - March 2016
Bengal College of Pharmaceutical Sciences and Research
Position
  • Professor (Assistant)
Education
August 2011 - August 2013
Guota College of Technological Sciences
Field of study
  • Pharmacology

Publications

Publications (45)
Article
Full-text available
Pharmacovigilance encompasses the science and practice related to the detection, assessment, understanding and prevention of adverse effects of drugs or any other possible drug-related problems. Recently, its purview has been widened to include herbal, traditional and complementary medicines, with the goal to comprehensively detect, assess, underst...
Article
Full-text available
To address the reasons for it is important to understand the knowledge, attitude and practices (KAP) of all pertinent stakeholders. This multicentrrising burden of Diabetes mellitus in India this survey is aimed at understanding the KAP quotients of the community regarding knowledge of laypersons regarding diabetes mellitus as this is lacking in In...
Article
Full-text available
The study is aimed at the evaluation of potential activity of and possible interaction with metformin in animal Models of Diabetes Mellitus. Study objectives include study the anti-diabetic effect of for Diabetes Mellitus in animal models and also to study the effect of Abelmoschus esculentus with metformin and explore any interaction. Plant materi...
Article
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This narrative review focussed on Diabetes which has emerged as a significant public health problem after cardiovascular diseases and the sixth leading cause of mortality worldwide. India faces a massive burden of Diabetes, which parallels a similar rise in obesity and metabolic syndrome. (Diabetes mellitus currently had a global prevalence of 6.4%...
Article
Full-text available
Objectives: This meta-analysis of randomized clinical trials (RCT) intends to evaluate the efficacy of DPP4 Inhibitors (DPP4I) compared with placebo, other antidiabetics (or DPP4I) on renal outcomes, adverse events (AEs), and all-cause mortality. Methods: We searched relevant scientific database for RCTs with DPP4I and prespecified renal end poi...
Article
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Objectives Data from point prevalence surveys (PPSs) in India are scarce. Conducting PPSs is especially challenging in the absence of electronic medical records, a lack of dedicated resources and a high patient load in resource-poor settings. This multicentre survey was conducted to provide background data for planning and strengthening antimicrobi...
Article
Full-text available
Purpose: This multicentric questionnaire-based study was undertaken to address the lack of systematic background data on the knowledge, attitudes, and practices among Indian physicians related to antimicrobial use and resistance. Materials and Methods: A validated structured study questionnaire was used for capturing respondent particulars, antimic...
Article
Full-text available
Background: To address the reasons for inappropriate use of antimicrobials, it is important to understand the knowledge, attitude and practices (KAP) of all pertinent stakeholders. This multicentric survey is aimed at understanding the KAP quotients of the community regarding antimicrobial use and antimicrobial resistance (AMR), as such informatio...
Article
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The objective of this review is to explore multifactorial aspects concerning possible use of zebrafish as a model system for Diabetes Mellitus. For the purpose of this review, bibliographic searches were performed under Pubmed, Medline and Google scholar for articles indexed in these databases ranging from 2000 to 2019. Zebrafish has evolved as a s...
Article
Syzygium samarangenseis an indigenous herb growing ubiquitously in various parts of India.The present review aims to unravel the recent findings with respect to the flavonoids and their bioactivity isolated from the extracts and fractions of this plant. Extensive literature and compendial survey (2001-2019) was performed of existing bibliographic d...
Article
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The herb Neptunia prostrata Linn. which belongs to Mimosaceae family has been used in folkloric medicine in the Northeastern states of India, Assam and Tripura by indigenous herbal healers since time immemorial but there is a scarcity of any background study documenting its use as an antimicrobial herb. This unmet need led to the present study bein...
Article
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Amorphophallus paeoniifolius (Dennst.) Nicolson is a tuberous plant commonly used in Ayurvedic medicines as well as tribal medicines in India. It is an endogenous plant which has been used in various medicinal purpose from ancient times. The study purpose involves the phytochemical screening, extraction and In vitro analysis for Antioxidant and An...
Article
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The aim of this review is to provide a comprehensive summary of natural based anti-fertility agents in males and females throughoutthe world by various tribes and ethnic groups. The present study explores the reviews published in this domain from 2006-2018. A comprehensive bibliographic database and abstracting systems such as Journal of Traditiona...
Article
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Vitamin B12 and Vitamin D insufficiency has been observed worldwide at all stages of life. It is a major public health problem, since the pathogenesis of several chronic diseases have been attributed to low concentrations of this vitamin. The present study throws light on the causal association of Vitamin B12 to cardiovascular disorders. Several ev...
Article
Full-text available
The objective of the present study is the thorough evaluation of the efficacy of a polyherbal ayurvedic formulation (PHAF), in streptozotocin- nicotinamide induced diabetes in wistar rats. A total of 30 adult rats (130-180 g) were employed. They were divided into five groups with 6 animals in each. Experimental diabetes was induced in 24 rats by a...
Article
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The present study evaluates the safety and efficacy of a Polyherbal Ayurvedic Formulation (PHAF), DIABIND alone and in combination with glibenclamide in streptozotocin-induced diabetes in wistar rats. A total of 30 adult rats (130-170g) were employed. They were divided into five groups with 6 animals in each. Experimental diabetes was induced in 24...
Article
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Datura stramonium is a widespread growing plant commonly known as Angel’s trumpet and it belongs to the family Solanaceae. The plant comprises bioactive constituents like scopolamine, hyosciamine, tropane alkaloids, tannin, proteins and carbohydrates. It has hallucinogenic effects as well as medicinal properties. Traditionally it is used in cough,...
Article
Full-text available
Antibody drug conjugates intends to pursue the monoclonal antibodies (mAbs) as the potent source of delivering cytotoxic drugs to more specific site which binds selectively to the antigen expressing tumor cells. Inspite of the facts, various other safety profile must be considered while designing and optimizing ADC such as selecting congruous targe...
Article
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A r t i c l e I n f o The present study is aimed at assessment of the innate pharmacological potential of leaves of Eryngium foetidum. The study objective includes the evaluation of the different hydro-alcoholic concentrations of Eryngium foetidum extracted and to find correlates with its yield value and the biological effect in animal models of he...
Article
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An experimental study with the objective to evaluate the acute toxicity study and anti-ulcerative property of the polyherbal formulation named-ASC01 (formulated in the same institute) was performed as per OECD guidelines 423. The polyherbal ayurvedic formulation (PHAF) is a scientifically developed combination of herbs that contains herbal ingredie...
Article
Full-text available
Snakebite is a major health hazard that leads to high mortality rate especially in India. The present review article focuses on the point of view of different in –vitro neutralization assays that serve as an index for assessing the status of therapy. For this purpose bibliographic and scientific literature articles in indexed journal databases were...
Article
Full-text available
An upcoming application of the Quality by Design(QbD) approach, is to the paradigm of analytical method development, the process commonly referred to as AQbD. Owing to the dearth of overviews on this topic, this paper endeavors to elucidate the AQbD process. Quality by Design also termed as QbD, is a holistic approach for quality assurance in pharm...
Article
Full-text available
Raja Chakraverty, et al.: Emerging therapeutic strategies for combating drug resistance in tuberculosis. The causative organism for tuberculosis Mycobacterium tuberculosis has shown the innate potential to develop resistance to the antimicrobial drugs used to cure the disease. The present review focuses on the collective and current understanding o...
Article
Full-text available
The aim of this present article is to underscore the recent evidence linking anticancer activity and free radical scavenging activity of mycotoxins and its significance in the development of newer anticancer drugs. For this purpose extensive bibliographic search of articles were conducted from different referred journals and indexing services. The...
Article
Full-text available
The purpose of this present work was to evaluate the antinociceptive efficacy of a combination of an opioid and a non-opioid analgesic in experimental models of nociceptive pain in swiss albino mice using established pharmacological models of pain. As of date, no single analgesic drug is considered perfect in the treatment of all types of pain. Eac...
Article
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The present study focused on the preliminary phytochemical screening and pharmacological evaluation of the dried fruit extract of Solanum indicum Linn. on experimental animal models of a variety of ailments viz. pain, fever, inflammation and CNS complication. The acute toxicity study as per OECD guidelines 425 revealed the drug to be safe till a do...
Article
Full-text available
The present study evaluates the hepatoprotective and antiulcer potential of the aqueous extract of aerial parts of Ocimum canum (AEOC). For the hepatoprotective study a total of 30 Swiss albino mice (n=6) weighing between 30-40 gm were used. They were divided into five groups. CCl 4 served as the inducing hepatotoxicant. AEOC was treated in the dos...
Article
Full-text available
Achondroplasia is a rare genetic disorder caused as a result of autosomal dominant mutation in the fibroblast growth factor receptor3 gene (FGFR3), which causes an abnormality of cartilage and bone formation. It is rare and happens in about 1:40,000 births and its homozygous form can be fatal. A single abnormal gene is enough to cause achondroplasi...
Article
Full-text available
Medicinal plants are the inherent part of Ayurvedic system of medicine. Different forms of plant extract are used in the Ayurvedic treatment regimen. But interestingly the uses of plant either partly or fully in Ayurveda, is not only limited to its direct use in therapeutics, but they are used indirectly in several other places of interest, which a...
Article
The history of herbal medicines is as old as civilization. For this purpose of ascertaining the phytochemical constituents, the present work was performed into the phytochemical investigation of the plant Avicenna alba. Separation and isolation of the constituents of interest, characterization of isolated compounds and investigation of the biosynth...
Article
A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the blood stream, this promotes healing to an injured area of the body. The advantage of a transdermal drug delivery route is that the patch provides a controlled release of the medication into the patient,...
Article
Full-text available
Mikania scandens is a rapidly growing herbaceous to semi-woody, perennial vine. It grows quickly over other plants such as young trees, smothering them; it can climb trees up to 25 m tall. Although not as serious a weed as M. chordate, in Southeast Asia it has become a hard to eradicate weed of tea, rubber, and other plantation crops. It also reduc...
Article
Full-text available
Oral controlled drug delivery systems represent the most popular form of sustained drug delivery systems for the obvious advantages of oral route of drug administration. Such systems release the drug with constant or variable release rates. The oral controlled release systems shows a typical pattern of drug release in which the drug concentration i...

Questions

Questions (8)
Question
How to select a statistical test for testing of hypothesis between 2 or more groups ?
Question
Can anyone help with the procedure and steps to be maintained in doing a survival
analysis of two different regimen of drugs ?
Question
Need a list of names of  In vitro tests that can be performed for assessing the effects of herbal drug extracts on diabetes mellitus ?
Question
What are the broad points of difference between protein based drug designing and structure based drug designing ?
Question
Can you suggest some established chemical inducers of epileptic seizures in rodents apart from PTZ alongwith dose and treatment period etc.?
Question
Can you suggest any specific animal models for induction type -2 diabetes mellitus in rodents and its brief protocol ?

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