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Raj kumar Manchanda

Raj kumar Manchanda
Directorate of AYUSH · Health and Family Welfare Department

M.D.(Hom), M.B.A.(Health care)

About

182
Publications
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Publications

Publications (182)
Article
Introduction: Mentha piperita L, a lesser-known and partly proved drug in homoeopathy, is used extensively as a herbal medicine. Objective: The objective of this study is to elicit the pathogenetic response of Mentha piperita in comparison to placebo. Materials and Methods: A multi�centre, double-blind, placebo-controlled and randomised clinical t...
Article
Full-text available
Objective: To assess the efficacy and safety of Chyawanprash in preventing SARS-CoV-2 infection among health care personnel working at COVID-19 isolation ward. Setting: A hospital designated as COVID-19 care centre in Delhi, India Participants: Apparently healthy health care workers (HCWs) of age 20 to 60 years who were RT PCR negative and asymptom...
Article
Full-text available
Background/Objective During the coronavirus disease 2019 (COVID-19) pandemic, several homeopathic prognostic factor research (PFR) projects have been undertaken. We found two projects with comparable outcomes to assess consistency and possible flaws. Methods Two comparisons were made. (1) Outcome of a PFR data collection from the Liga Medicorum Hom...
Article
Background/Objective Prognostic factor research (PFR), prevalence of symptoms and likelihood ratio (LR) play an important role in identifying prescribing indications of useful homeopathic remedies. It involves meticulous unbiased collection and analysis of data collected during clinical practice. This paper is an attempt to identify causes of bias...
Article
Background Visceral leishmaniasis (VL) is a neglected tropical disease that is fatal if treatment is not given. The available chemotherapeutic options are unsatisfactory, and so complementary therapies like homeopathy might be a promising approach. Methods A nosode from a pure axenic culture of Leishmania donovani was prepared and screened for its...
Article
Homeopathic medicines affect physical properties of matter which depend on the characteristic and the potency of the medicine1. These effects can be explained from two aspects: (a) classical and (b) quantum electrodynamical. Using three different sets of experiments where homeopathic medicines have affected the physical properties of matter, we hav...
Article
Full-text available
As per the latest Globocan statistics, the high prevalence rate of breast cancer in low- and middle-income countries has led to it becoming the most common cancer to be diagnosed, hence posing a major public health challenge. As per this data, more than 11.7% of the estimated new cancer cases in 2020 were due to breast cancer. A small but significa...
Preprint
BackgroundCOVID 19 pandemic has evolved as a unique unprecedented global health crisis that has affected severely the economies and daily lives of people. Despite the diligent worldwide efforts to contain it, there is an exponential rise in cases. Associated serious morbidity and mortality has continued the efforts towards a clinically proven proph...
Article
Background: New effective, economical and safe antimalarial drugs are urgently needed due to the development of multi-drug-resistant strains of the parasite. Homeopathy uses ultra-diluted doses of various substances to stimulate autoregulatory and self-healing processes to cure various ailments. The aim of the study was to evaluate the in vitro an...
Article
During the past century, the amount of information about homeopathic medicines has grown dramatically. However, the recent coronavirus disease 2019 pandemic has shown that homeopathic practitioners do not use more medicines than a century ago and they seem to use less symptoms to find the proper medicine. This could be explained by the fact that th...
Article
Objectives: The modified Naranjo algorithm assesses the physician assigned cause-effect relationship for homeopathic medicines. It is being adopted in homeopathy researches, but not yet validated systematically. We intended to validate the modified Naranjo algorithm by examining its psychometric properties. Methods: An online survey sought agreemen...
Article
Background/objective: Coronavirus disease 2019 (COVID-19) is a new disease; its clinical profile and natural history are evolving. Each well-recorded case in homeopathic practice is important for deciding the future course of action. This study aims at identifying clinically useful homeopathic remedies and their prescribing symptoms using the prog...
Article
Achtergrond Fibroadenoom van de borst is de meest voorkomende kwaal bij vrouwen met een aanzienlijk risico op overlijden. Uit de beschikbare literatuur blijkt dat borsttumoren verdwijnen door homeopathische behandeling. De huidige studie evalueerde de rol van homeopathische behandeling op borstfibroadenoma met behulp van ‘Triple assessment criteria...
Article
Rationale & objective: The concept of Prakriti is unique to Ayurveda, which is used for deciding the preventive and curative strategy to be adopted in the treatment of patients. It is the total of anatomical, physiological, and psychological domains of an individual. The diseases often manifest by susceptibility that depends upon Prakriti of indiv...
Article
Objective The aim of the study was to identify indicated homeopathic remedies based on the clinical characteristics of coronavirus disease 2019 (COVID-19) patients in India. Methods In this retrospective, cohort study, confirmed COVID-19 patients admitted at a COVID Health Centre in New Delhi between April 29 and June 17, 2020 were given convention...
Article
The process of wound healing is a dynamic event that starts with inflammation, proliferation, and cell migration of various types of fibroblast cells. Therefore, identification of potential molecules which may increase the wound healing capacity of fibroblast cells is crucial. A novel hydroalcoholic formulation of belladonna (SKRIN), was developed...
Article
Background A novel pandemic disease offered the opportunity to create new, disease-specific, symptom rubrics for the homeopathic repertory. Objective The aim of this study was to discover the relationship between specific symptoms and specific medicines, especially of symptoms occurring frequently in this disease. Materials and Methods Worldwide co...
Article
Background: Although the symptomatology of Cuprum metallicum is quite vast, its other salts have fragmentary proving. Thus, homoeopathic pathogenetic trial for Cuprum aceticum (Cu acet.) was taken up. Objective: To elicit the pathogenetic response to Cu acet. in homoeopathic potencies on healthy human provers. Materials and Methods: A multi-center,...
Article
Full-text available
Background: Despite standard management, healing rate of Diabetic Foot Ulcers (DFUs) remains low, posing risk of lower extremity amputation. Objectives: This study was undertaken to evaluate if Calendula Q has added benefit over individualized homoeopathic intervention (IHI). The primary objective was to achieve complete epithelialisation within 20...
Article
Full-text available
To evaluate the effects of homeopathy on the treatment of acne using specific outcome measures related to severity and disability.
Article
Japanese encephalitis virus (JEV) is the main cause of viral encephalitis resulting in more than 68 000 clinical cases every year with case fatality rate as high as 30−40% for which no specific treatments are available. We have recently exhibited belladonna may be widely applicable for the treatment of various neurological disorders. Therefore, we...
Article
Full-text available
Lessons learned: Conventional medicine and homeopathy work well together. Quality of life improves with additive homeopathy in patients with non-small cell lung cancer (NSCLC). Survival improves with additive homeopathy in patients with NSCLC. Background: Patients with advanced non-small cell lung cancer (NSCLC) have limited treatment options. A...
Article
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Background: Anaemia in children has signifi cant adverse health consequences and is a major public health problem. Objective: The objective of this study is to identify effi cacy of Ferrum phosphoricum 3X (FP) and Ferrum metallicum 3X (FM) in changing haemoglobin (Hb) levels in school-going children, 12–14 years of age with Iron Defi ciency Anaemia...
Article
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Background: Polar symptoms represent the most challenging rubrics in the homoeopathic repertories, despite their frequent use. Objective: The study objective was to assess the relationship between 27 polar cough symptoms, 3 non-polar cough symptoms and 30 general polar symptoms and successful response to specific homoeopathic medicines. Materials a...
Article
Background Acne is often treated at homeopathic clinics in India based on existing literature without using any measurable parameters and the outcomes are seldom reported, hence this study. Objective To evaluate the effects of homeopathy on the treatment of acne using specific outcome measures related to severity and disability. Methods It is an op...
Article
Background Leishmaniasis is one of several neglected tropical diseases that warrant serious attention. A disease of socio-economically poor people, it demands safer and cheaper drugs that help to overcome the limitations faced by the existing anti-leishmanials. Complementary or traditional medicines might be a good option, with an added advantage t...
Article
Background Polar symptoms (PS)—symptoms with opposite values—are frequently used in homeopathy, but have many misleading entries in the repertory. This is caused by using absolute occurrence of symptoms, causing the same medicine to appear in both (opposite) symptom rubrics, and by lack of comparison with other medicines. Some PS, like ‘aversion/de...
Article
Objectives Homeopathy remains one of the most sought after therapies for urological disorders. The aim of this paper was to systematically review the available clinical researches of homeopathy in the said conditions. Content Relevant trials published between Jan 1, 1981 and Dec 31, 2016 (with further extension up to Dec 31, 2017) was identified t...
Article
Belladonna has diverse pharmacotherapeutic properties with shadowy history of beauty, life, and death. Alkaloids present in belladonna have anti-inflammatory, anticholinergic, antispasmodic, mydriatic, analgesic, anticonvulsant, antimicrobial, which makes it widely applicable for the treatment of various diseases. However, due to its associated tox...
Article
Background Breast cancer is the second leading cause of cancer-related deaths in women. Conventional treatment such as chemotherapy, hormonal therapy and radiotherapy has decreased the mortality rate among cancer patients but has also revealed long-term side effects. Drug resistance and toxicity to normal cells compound the problems associated with...
Article
Objective Prolonged use of nonsteroidal anti-inflammatory drugs is associated with severe side effects and toxicity. Therefore, we studied the anti-inflammatory role of Calcarea carbonica which had minimal toxicity at the low doses. Methods THP-1 human mononuclear cells were treated with C. carbonica to evaluate the 50% cytotoxicity concentration...
Article
Background Fibroadenoma of breast is the commonest ailment of women with significant morbidity. Available literature revealed that breast tumour recedes by homoeopathic treatment. The present study evaluated the role of homoeopathic treatment on breast fibroadenoma by using ‘Triple assessment criteria’ and to explore the mechanism, whether homoeopa...
Article
Full-text available
Background Randomized placebo-controlled trials are considered to be the gold standard in clinical research and have the highest importance in the hierarchical system of evidence-based medicine. However, from the viewpoint of decision makers, due to lower external validity, practical results of efficacy research are often not in line with the huge...
Article
Background : In course of diabetes, some 20–90% of individuals eventually develop diabetic neuropathy. Looking at the disease burden research studies in Homoeopathy were conducted and have shown positive results. These studies were not robust enough to prove the efficacy of individualized homoeopathy. Objective : To assess efficacy of individualiz...
Article
Japanese encephalitis (JE) is now a public health concern due to limitation of the available vaccine and nonexistence of specific antiviral therapy and thus demands new potential therapeutical strategies. The present study was conducted to evaluate the effect of atropine in controlling JE virus infection in chick embryo, which is already establishe...
Article
Full-text available
Emergence of influenza A H3N2 is alarming. Strain 2013 H3N2 has H1 subtype Haemagglutinin (HA) gene segment replaced with a H3 HA gene segment. The vulnerability of the humans to H3 may be directly proportional to the HA alterations. Therefore, we studied this strain and analyzed its sequence and structural divergence and compared it with 2009 H3N1...
Conference Paper
A024. An Assessment of a Public Health Initiative of Homeopathy for Primary Teething Background: A public health initiative, ‘Homoeopathy for the Healthy Child’,was undertaken focusing promotion of healthy teething by provision of home-based care through pre-identified homeopathic medicines for complaints during primary teething. The paper reports...
Article
Full-text available
Background: A systematic review on homoeopathic pathogenetic trials (HPTs) from 1945 to 1995 was published in 2007, and the basic question whether the effect produced by homoeopathic drugs in healthy human volunteers is equivalent to placebo or otherwise remained unanswered. There is a need to take up another review of HPTs conducted in the last tw...
Article
Full-text available
Background: Hypertension (HTN) is a leading risk factor for death and disability and responsible for over 1.6 million deaths in India. Clinical case reports, observational studies and randomised controlled trials show the effects of homoeopathic medicine in HTN. Objectives: The results of this study will add to the evidence of effectiveness of indi...
Article
Background: Hyperoxaluria and calcium oxalate crystal deposition in the kidneys lead to overproduction of reactive oxygen species, resulting in the development of oxidative stress and renal injury. At the cellular levels, mitochondria and NADPH oxidase involved in reactive oxygen species production play a crucial role in the pathogenesis of hyperox...
Article
Full-text available
Introduction: Malaria is a public health emergency in India and Odisha. The national malaria elimination programme aims to expedite early identification, treatment and follow-up of malaria cases in hot-spots through a robust health system, besides focusing on efficient vector control. This study, a result of mass screening conducted in a hot-spot...
Preprint
Full-text available
Chemoprofiling of homoeopathic drug/tincture (HT) represents a comprehensive approach for evaluation of quality, purity, safety and efficacy of HT. According to the phytoequivalence concept the full HT can be seen as the active compound, because the several constituents act together being responsible for its therapeutic effect. Coffea arabica (Coff...
Article
Full-text available
Homoeopathy is a system of medicine that treats the individual with medicines that stimulate the body’s self-healing mechanisms to restore its natural equilibrium. The physician treats the patient as a whole rather than a particular clinical condition or body part, by taking into account the patient’s actual symptoms in addition to his/her individu...
Article
Full-text available
Purpose Urinary calcium creatinine ratio (UCaCrR) is a reliable indicator for monitoring hypercalciuria following vitamin D supplementation. However, the reference range varies from region to region. Previous studies did not take vitamin D and parathyroid hormone status into account while evaluating UCaCrR. Hence, we undertook this study to establi...
Research Proposal
Full-text available
Background and Objectives: The literature cites a large number of homoeopathic medicines for the treatment of warts. Studies on warts are based on experiences of individual practitioners and do not give specific factors, which are responsible for making a successful prescription for the treatment of warts. The present study was designed as a multic...
Article
Full-text available
Aim: Assessment of group‑confined likelihood ratio (GCLR) for the symptom ‘Headache’ from among 20 lesser‑known remedies clinically verified by the Central Council for Research in Homoeopathy during the period 2012–2018. Materials and Methods: Analysis of data of the clinical verification study, which was a multicentric, open‑label, observational c...
Article
Full-text available
High-performance Thin Layer Chromatography (HPTLC) and UV spectroscopy is an important tool for the qualitative and quantitative phytochemical, chemo profiling and marker compound analysis of homoeopathic drugs/tinctures (HT). According to the phytoequivalence concept the full HT can be seen as the active compound, because the several constituents...
Article
Background Dengue is an emerging threat to public health. At present, no clear modalities are available for the prevention and management of thrombocytopenia due to dengue. This article reports the clinical outcomes of integrative homeopathic care in a hospital setting during a severe outbreak of dengue in New Delhi, India, during the period Septem...
Research
Full-text available
Chemoprofiling of homoeopathic drug/tincture (HT) represents a comprehensive approach for evaluation of quality, purity, safety and efficacy of HT. According to the phytoequivalence concept the full HT can be seen as the active compound, because the several constituents act together being responsible for its therapeutic effect. Coffea arabica (Coff...
Article
Full-text available
High-performance Thin Layer Chromatography (HPTLC) and UV spectroscopy is an important tool for the qualitative and quantitative phytochemical, chemo profiling and marker compound analysis of homoeopathic drugs/tinctures (HT). According to the phytoequivalence concept the full HT can be seen as the active compound, because the several constituents...
Article
Background: Hygrophila auriculata (Schumach.) Heine synonym Hygrophila spinosa T. Anderson is used in the homoeopathic system of medicine belongs to the family Acanthaceae. Plant contains terpenoids, alkaloids, flavonoids and is traditionally known as an aphrodisiac, renal tonic and for its health-promoting properties, this drug is most popularly u...
Article
Full-text available
Background Based on a pluralistic approach to health care, India offers a range of medical treatment modalities to its population. In that context, the government of India aims at providing its people with wider access to homeopathy. This article provides insight into the infrastructural support put in place by the government to meet that aim. Data...
Article
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Introduction: The first-of-its-kind World Integrated Medicine Forum (WIMF) on the regulation of homoeopathic medicinal products (HMPs) which was attended by various stakeholders from 23 countries witnessed rigorous discussions to strengthen existing regulatory framework of homoeopathic medicines in the world, as well as to bring harmony within the...
Article
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Background and Objective: Homoeopathy is one of the various alternative systems of medicine prevalent in India. A survey was conducted during the month of January–February 2017 in a congregation at Sangam, Allahabad, to know about the awareness of general population about Homoeopathy. Methods: A cross-sectional survey was conducted on patients and...
Article
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Objective: The aim of this study was to investigate, the inhibitory effect of the homoeopathic drugs – Eupatorium perfoliatum and Crotalus horridus in experimental models of inflammation and Complete Freund's Adjuvant (CFA)-induced arthritis with evaluation of their safety aspects by acute and subacute toxicity studies. Materials and Methods: Anima...
Article
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Context: Scientific assessment of proving symptoms or already recorded symptoms in patients refers to Clinical Verification (CV). There are serious shortcomings of existing methods of CV, mostly arising from qualitative observations made on absolute occurrence of symptoms instead of relative ones. This problem can be resolved by the use of the Like...
Article
Full-text available
Background: Urolithiasis is the most common disease of urinary tract found worldwide. There are several approaches for the treatment of urolithiasis that include the use of various synthetic and natural drugs and/or surgery in the conventional system of medicine. Objective: This study was taken up to evaluate the efficacy of Lycopodium clavatum in...