Raheleh Rahbarian

Payame Noor University | PNU · Department of Biology

Background: Cervical cancer is one of the most prevalent gynecologic cancers associated with high morbidity and mortality worldwide. There is mounting evidence indicating an association between the 9p21 locus genetic variants with susceptibility to various human malignancies. In this current study, we aimed to evaluate the potential relationship be...

Vit v 1 as a lipid-transfer protein is a major allergen of grapes (Vitis vinifera) that elicits food allergy in many patients in Iran. Todays, recombinant allergens have a promising future in improving in vivo and in vitro diagnostic tests. In this study, we aim to achieve high-level expression of recombinant Vit v 1 allergen in Pichia pastoris exp...

Background Cervical cancer is one of the most prevalent cancers among women and is associated with high morbidity and mortality. Several factors are involved in the pathogenesis of cervical cancer including viral infections and/or genetic modifications that include single nucleotide polymorphisms (SNPs). Methods We aimed to investigate the associa...

Background and Objectives Herbal medicines have fewer side effects than chemical drugs. In this regard, researchers are looking to find herbal ingredients to heal diabetic wounds. Saffron is a powerful antioxidant that can be effective in treating diabetic wounds. This study aims to evaluate the effect of saffron’s main ingredients (crocin and safr...

Gap junctions (GJs) are intercellular channels consisting of connexin proteins that allow the communication/cross-talk of molecules between neighboring cells. Connexins play an important role in various cellular processes including proliferation, cell signaling, homeostasis, differentiation, invasion, and metastasis. Connexins are involved in the d...

St. John's wort is a valuable medicinal plant that has been used for more than 2000 years and is known globally as one of the best medicines in the context of neurological diseases and skin health. As the leading sciences worldwide, plant tissue culture and micropropagation by genetic engineering methods are important indicators of agricultural bio...

Background: Janus kinase 2 (JAK2) is a tyrosine kinase located in the cytoplasm that plays a critical role in the signal transduction of cytokines and growth hormones. The conversion of valine to phenylalanine at the polypeptide position 617 results in the JAK2 (V617F) mutation, which often found in patients with myeloproliferative neoplasms (MPNs...

Purpose : Lettuce has demonstrated antidiabetic, antioxidant and anti-inflammatory activities. In the present work the hypolipidemic effect of chronic administration of aqueous-ethanolic extract of lettuce (Lactuca sativa) seed was investigated. Hyperlipidemic patients meeting the inclusion criteria were randomly assigned into the treatment and pla...

Abstract The present investigations report on the green bio-synthesis of silver nano-particles (Ag- NPs) using silymarin extracted from callus cultures of Silybum marianum. Ag-NPs were characterized with the help of UV-Visabsorption spectroscopy, FTIR, XRD and SEM. The results obtained by UV-Vis absorption spectroscopy indicated that the concentrat...

BACKGROUND: Type one diabetes mellitus (DM) is a multisystem disorder whose effects are observed in the reproductive system. Considering the role of curcumin in lowering blood glucose and enhancing antioxidant defense, this research aimed to determine protective effect of curcumin on quality parameters of sperm and testicular tissue alterations in...

Aims Type 1 diabetes is a high-prevalent endocrine disease and causes oxidative stress in the testis tissue. In the treatment of diabetes, the tendency toward herbal medicines use is increasing. This study aimed to investigate the crocin effect on the Bax, Bcl2 (B-cell lymphoma 2), and anti-oxidant levels of streptozotocin-induced diabetic rats. Me...

Purslane (Portulaca oleracea L.) is a local plant in Iran that can easily breed. Chromium is a heavy metal that causes toxicity for the growth and development of plants. To study the effects of potassium dichromate on growth, efficiency of photosystem II (Fv/Fm), cell membrane stability index (MSI), indexes of oxidative stress and antioxidant prope...

In order to investigate effects of Cr stress on growth, photosynthetic indexs and the activity of antioxidant enzymes in Portulaca oleracea L.(Purslane), an experiment in the greenhouse of Ferdowsi University of Mashhad, was done in a completely randomized design with three replications of five levels (0, 25, 50, 75 and 100 ppm). The amount of Cr+6...

Althaea officinalis (Malvacaeae) is a famous medicinal herb. It is considered as a source of some pharmaceutically important compounds including scopoletin, which has antifungal, antioxidant and anticancer activity. In this study we made an attempt to investigate the effect of the yeast extract, a biotic elicitor, on production of scopoletin as wel...

BACKGROUND AND OBJECTIVE: Hormonal disorders along with oxidative stress and inflammation in ovarian tissue lead to anovulation in polycystic ovary syndrome (PCOS) patients. Considering antioxidant effect of Artemisia absinthium, purpose of this study is to determine the effect of aqueous extract of Artemisia absinthium on serum levels of sex hormo...

Launaea Acanthodes is extensively used in the semiarid region of Iran for treatment of seizure. However, the underlying mechanism has not been studied well. In our previous study we showed that Launaea Acanthodes extract could effectively stimulate GABA release from PC12 cell culture. The critical role of astrocytes in epileptic brain in regulation...

The goal of this research was to study the curing behavior and biodegradability of DER 736 modified with epoxidized oleic acid. DER 736 epoxy resin is a flexible, low viscosity, and light color resin for use in coatings and adhesives. This epoxy resin is a liquid reaction product of epichlorohydrin and diproylene glycol. In this paper, the efficien...

In recent years, expansion in industrial activities and urbanization has led to accumulation of high concentration of chromium in soil and water resources, which is a serious danger for environment and human health. In this research, potential of Portulaca oleracea in phytoremediation of Cr+6 polluted soil with different chromium concentration was...

Background: Angiogenesis in cancer tissue leads to development of cancer and inhibition of angiogenesis is one of the goals of cancer treatment. In traditional medicine, Allium sativum L. and Ferula assa-foetida are considered as the most important medicinal plants. In addition, the effect of electromagnetic field on the cell growth in different as...

13 Effect of Saline Soil Texture on Launaea acanthodes (Boiss.) O. Kuntze Companion Species Richness and Diversity in Neishabour, Rasavi- Khorasan Province, Iran Raheleh Rahbarian¹* and Atena Eslami Farouji¹ Biology Scientific group, Payame Noor University, Khorasan Province, Iran Abstract It should be accepted that there are certain relationships...

authors: Raheleh Rahbarian and Atena Eslami Payam Noor University of Mashhad Abstract—Herbal treatment is very common around the world. The use of medicinal plants has increased due to chemical drugs. Identification of medicinal plants in natural habitats and their companion species as the first step and evaluation of their properties as the second...

A system of ordinary differential equation, which describes the interaction of HIV and T cells in the immune system, is utilized, and optimal representing drug treatment strategies of this model are explored. Control model, in the sense of an optimal control problem shows the strategy of chemotherapy treatment setting through a dynamic treatment. I...

In order to evaluate the physiological and biochemical traits regarding drought tolerance and further to determine the best criteria for screening and identification of drought tolerant chickpea genotypes, an experiment was conducted in controlled conditions in the Plant Science Research Center of Ferdowsi University of Mashhad in Iran. In this stu...

In order to evaluate morphological and physiological traits related to drought tolerance and to determine the best criteria for screening and identification of drought-tolerant genotypes, we grew two tolerant genotypes (MCC392, MCC877) and two sensitive genotypes (MCC68, MCC448) of chickpea under drought stress (25% field capacity) and control (100...