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Raghavendra M Rao

Raghavendra M Rao
Central Council for Research in Yoga and Naturopathy · Yoga and Naturopathy

BNYS; PhD (Yoga and Life Sciences)

About

102
Publications
20,497
Reads
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2,049
Citations
Introduction
Integrating Yoga in Oncology, Cardiology and NCD management. Basic research on naturopathic modalities, lifestyle interventions and large multicentric trials
Additional affiliations
October 2019 - present
Central Council for Research in Yoga and Naturopathy
Position
  • Director
October 2007 - October 2019
HCG Oncology
Position
  • Senior Scientist and Head CAM program
Description
  • On deputation to Ministry of AYUSH, Govt of India
October 2007 - August 2015
Healthcare Global enterprises Ltd.
Position
  • Head of Department

Publications

Publications (102)
Article
Background: While the benefits of yoga are well established across the world, there are limited studies exploring the long-term interrelation between yoga, meditation, and health. Specifically, there is limited research exploring the differences in Health-Related Quality of Life (HRQOL) among regular meditators and non-meditators. Objective: The...
Preprint
BACKGROUND Although the benefits of yoga are well established across the world, there are limited studies exploring the long-term interrelation between yoga, meditation, and health. Specifically, there is limited research exploring the differences in health-related quality of life (HRQOL) among regular meditators and nonmeditators. OBJECTIVE This...
Article
Background: Chanting “OM” is a form of meditation that has numerous health benefits. However, the neurophysiological mechanisms underpinning its effect are surprisingly scarce. The present study aimed to investigate the effect of OM chanting on autonomic modulation, using heart rate variability (HRV), on experienced yoga practitioners and yoga naïv...
Article
Full-text available
Background/Introduction Endothelial dysfunction plays an important role in the pathophysiology of cardiovascular diseases and diabetes. Studies reported either an improvement in endothelial function by yoga and meditation or no significant effect. A systematic review and meta-analysis of effect of yoga on endothelial function is not available. Pur...
Article
Objectives Arterial stiffness is a major cardiovascular (CV) risk and an independent strong predictor of CV morbidity and mortality. The aim of this systematic review is to evaluate the clinical or interventional studies that assessed the effectiveness of yoga on arterial stiffness in participants of any age or sex, healthy or with any conditions....
Article
Aim: Lifestyle is an important risk factor for increasing the prevalence of diabetes in the Indian population. In this study, we evaluate the effects of naturopathy treatment, salt-restricted low-calorie diets, and yoga in long-term glycemic control in patients with type 2 diabetes mellitus. Methods: In this prospective, longitudinal, two-arm co...
Chapter
Ayurveda, which literally translates to “knowledge of life,” defines disease as the end result of “living out of harmony” with one's constitution. An imbalance in the dhatus could cause skin disease. An imbalance in these dhatus could cause skin disease. Ayurveda classifies three types of psychological states: the Tamo guna (inertia), Rajoguna (act...
Article
Full-text available
Background Eribulin mesylate is a non-taxane microtubule inhibitor which can be used after anthracycline and taxane treatment in patients with metastatic breast cancer (MBC). The purpose of this study was to investigate the efficacy and safety of eribulin monotherapy in heavily pretreated patients with MBC. Methods In this study, a total of 45 eli...
Research
Full-text available
Introduction Breast cancer is the most common cancer in women, affecting almost 1 in 8 women worldwide, and the second most common cause of cancer deaths in women and one of the leading cancers in India. 1,2 Metastatic breast cancer (MBC) remains an incurable disease despite considerable progress and new treatment options. 3,4 Anthracyclines and ta...
Article
Background Yoga is very effective in improving health especially cardio-respiratory fitness and also overall performance in adolescents. There are no large numbers of randomized controlled studies conducted on comparing yoga with physical activity for cardio-respiratory fitness in adolescent school children with large sample size. Objective Aerobi...
Conference Paper
Breast cancer is one of the major type of cancer which is the leading cause of death in women. The research work is carried out on the real data of patient records obtained from HealthCare Global Enterprises Ltd (HCG) hospitals. The work analyzes the four major class variables in the dataset, namely death, progression, recurrence and metastasis. Th...
Article
Full-text available
Background Cancer-related fatigue is widely prevalent in cancer patients and affects quality of life in advanced cancer patients. Fatigue is caused due to both psychologic distress and physiological sequel following cancer progression and its treatment. In this study, we evaluate the effects of yogic intervention in managing fatigue in metastatic b...
Article
Full-text available
Background The diagnosis and treatment of cancer poses severe psychologic distress that impacts functional quality of life. While cancer directed treatments are directed purely against tumor killing, interventions that reduce treatment related distress and improve quality of life are the need of the hour. Yoga is one such mind body intervention tha...
Article
Full-text available
Aims The aim of this study is to compare the effects of yoga program with supportive therapy counseling on mood states, treatment-related symptoms, toxicity, and quality of life in Stage II and III breast cancer patients on conventional treatment. Methods Ninety-eight Stage II and III breast cancer patients underwent surgery followed by adjuvant r...
Article
Full-text available
Background Studies have shown that distress and accompanying neuroendocrine stress responses as important predictor of survival in advanced breast cancer patients. Some psychotherapeutic intervention studies have shown have modulation of neuroendocrine-immune responses in advanced breast cancer patients. In this study, we evaluate the effects of yo...
Article
Full-text available
Aim Breast cancer has become a pandemic with an ever-increasing incidence. Although better diagnostics and treatment modalities have reduced mortality, a large number of survivors face cancer and treatment-related long-term symptoms. Many survivors are taking up yoga for improving the quality of life (QoL). The present study attempts to evaluate pr...
Article
Full-text available
Abstract – Objective: The best treatments for metastatic lung cancer patients are palliative.We evaluated the effects of metronomic chemotherapy on survival outcomes in this population. Patients and Methods: Thirty-four subjects with treatment refractory (n=26) and treatment naïve (n=7) metastatic lung cancer were included in an open-label single a...
Article
Full-text available
Introduction: Palliative care is usually delivered late in the course of illness trajectory. This precludes patients on active disease modifying treatment from receiving the benefit of palliative care intervention. A survey was conducted to know the opinion of oncologists, oncology nurses, and patients about the role of early specialist palliative...
Article
Background Although biopsy is the gold standard for diagnosis, cytological material has often been used to assist in making a pathologic diagnosis as well as for molecular testing in certain cancers such as in the lung, cervix, and head/neck. Objective Our objective is to share experience from our institution in the use of cytological material in s...
Article
Full-text available
Background: Migraine is associated with autonomic symptoms. The growing body of literature suggests that the dysfunctional autonomic nervous system might play a pivotal role in the pathogenesis of migraine. Thermal therapies have been hypothesized to modulate these changes and alleviate pain. However, data regarding the efficacy of hydrotherapy in...
Article
Full-text available
Introduction: Home-based palliative care is an essential model of palliative care that aims to provide continuity of care at patient's own home in an effective and timely manner. This study was a pilot test of triage coding system in home-based palliative care using Edmonton Symptom Assessment System (ESAS) scale. Methods: Objective of the study...
Article
Background: Migraine is associated with autonomic symptoms. The growing body of literature suggests that the dysfunctional autonomic nervous system might play a pivotal role in the pathogenesis of migraine. Thermal therapies have been hypothesized to modulate these changes and alleviate pain. However, data regarding the efficacy of hydrotherapy in...
Article
Full-text available
To compare the effects of yoga program with supportive therapy on self-reported symptoms of depression in breast cancer patients undergoing conventional treatment. Ninety-eight breast cancer patients with stage II and III disease from a cancer center were randomly assigned to receive yoga (n = 45) and supportive therapy (n = 53) over a 24-week peri...
Article
Background: Patients' who are positive for kinase domain activating mutations in epidermal growth factor receptor (EGFR) gene, constitute 30-40% of non-small cell lung cancer (NSCLC), and are suitable candidates for Tyrosine Kinase Inhibitor based targeted/personalized therapy. In EGFR non-mutated subset, 8-10% that show molecular abnormalities su...
Article
Background: One of the genetic alterations implicated in tumor progression in colorectal cancers (CRCs) are abnormalities in Kristen Rat Sarcoma (KRAS) gene. Evaluation of KRAS mutation status is an important prognostic factor and has predictive value in deciding first line therapy based on monoclonal antibodies such as Cetuximab and Panitumumab i...
Article
The aim of the study was to test the efficacy of a one month in-patient naturopathy and yoga programme for patients with asthma. Retrospective data of 159 bronchial asthma patients, undergoing the naturopathy and yoga programme, was analyzed for Forced Vital Capacity, Forced Expiratory Volume at the end of 1 second, Maximum Voluntary Ventilation an...
Article
Full-text available
Type 2 diabetes is a major health problem in many countries including India. Yoga may be an effective type 2 diabetes prevention strategy in India, particularly given its cultural familiarity. This was a parallel, randomized controlled pilot study to collect feasibility and preliminary efficacy data on yoga for diabetes risk factors among people at...
Article
Full-text available
Context and Aims: Migraine is an episodic disabling headache requiring long-term management. Migraine management through Yoga therapy would reduce the medication cost with positive health benefits. Yoga has shown to improve the quality of life, reduce the episode of headache and medication. The aim of the present study was to evaluate the efficacy...
Article
Full-text available
Introduction: Spiritual well-being and fatigue are key parameters in assessing health related quality of life that determine treatment tolerance, treatment outcomes and reflect patient's coping ability in the illness-wellness disease trajectory. Materials and methods: A total of 200 patients on active cancer treatment were enrolled to the study....
Article
The choice of an appropriate treatment option in patients with inoperable or metastatic neuroendocrine tumours (NETs) is limited, and approximately 50 % of patients have advanced NET at diagnosis, and 65 % die within 5 years. Treatment with (177)Lu-DOTATATE ((177)Lu-[DOTA(0),Tyr(3)] octreotate) is a promising new option in the treatment of metastat...
Article
Full-text available
Context and aim: Complementary and alternative therapies (CAM) are gaining popularity amongst patients as add on to conventional medicine. Yoga stands third amongst all CAM that is being used by cancer patients today. Different schools of yoga use different sets of practices, with some using a more physical approach and many using meditation and/o...
Article
6624 Background: Chemotherapy induced nausea and vomiting is a common distressing symptom. In this study we evaluated the effects of Yoga vs. Jacobson’s relaxation training on CINV outcomes in chemotherapy naive patients undergoing moderately to highly emetogenic chemotherapy. Methods: One hundred and twenty patients who satisfied the selection cri...
Article
e19092 Background: Metastatic lung cancer patients are at best treated palliatively. We evaluated the effects of metronomic chemotherapy on survival outcomes in this population. Methods: Thirty four subjects with treatment refractory (n=26) and treatment naive (n=7) metastatic lung cancer were included in a open label single arm efficacy study of m...
Article
Full-text available
Distress is commonly seen in head and neck cancer patients undergoing radiotherapy. Causal factors of distress are multifactorial; which encompasses physical, psychological, spiritual, and existential factors with complex interrelationship among the factors. Thirty patients undergoing head and neck radiotherapy were included in the study. Patients...
Article
Background: Epidermal growth factor receptor (EGFR) mutation plays a vital role in the prognosis of patients with lung cancer. However, there is a dearth of studies on EGFR mutation in Indian population. In this retrospective study conducted at a network of tertiary cancer care centers across India, we evaluated the proportion of EGFR mutation in...
Article
Yoga is found to be effective in reducing stress levels and radiation-induced DNA damage, and improving the quality of life, in breast cancer patients. The present study was aimed at comparing the apoptotic index (AI) and DNA damage of advanced yoga practitioners with those of breast cancer patients. This cross-sectional pilot study compared three...
Conference Paper
Full-text available
J Clin Oncol 31, 2013 (suppl; abstr e19092)
Conference Paper
Background: Chemotherapy induced nausea and vomiting (CINV) is affected by both pretreatment patient factors, chemotherapy and antiemetic regimen and psychological interventions. In this study we evaluated the effects of mind body intervention such as yoga in modulating CINV outcomes controlled for the above factors. Methods: Chemotherapy naïve bre...
Article
Several studies have documented the beneficial short term effects of yoga in type 2 diabetics. In this prospective two-armed interventional randomized control study, 277 type 2 diabetics of both genders aged above 28 years who satisfied the study criteria were recruited from 5 zones in and around Bengaluru, India. They were allocated to a yoga-base...
Article
1093 Background: Chemotherapy induced nausea and vomiting (CINV) is affected by both pretreatment patient factors, chemotherapy and antiemetic regimen and psychological interventions. In this study we evaluated the effects of mind body intervention such as yoga in modulating CINV outcomes controlled for the above factors. Methods: Chemotherapy naïv...
Article
e12030 Background: This study elucidates data from a 5 year retrospective study evaluating survival rates and prognostic factors in breast carcinoma patients in a private cancer set up in south India. Methods: 1046 patients who were treated between years 2003 to 2008 were analyzed. Clinical data including stage, histopathology type, age, node posit...
Article
e11043 Background: Breast cancer patients younger than 40 years are known to have an aggressive disease than their older counterparts. In this correlational study involving Indian women with breast cancer; we analyzed if age is related to an aggressive histopathologic phenotype and biomarker expression. Methods: Paraffin embedded tissue blocks of h...
Article
e11511 Background: Adherence plays an important role in success of mind body interventions such as yoga. In this study we evaluated the effects of adherence to yoga intervention on psychological and quality of life outcomes. Methods: Adherence to yoga program was assessed in a randomized controlled trial comparing yoga (n=45) vs. supportive therapy...
Article
Full-text available
Exposure to pollutants in the environment, tobacco and alcohol consumption, poor oral hygiene and opportunistic viral infections are important aetiological factors in head and neck cancers. In this study, we evaluate the complex interrelationships between these factors and molecular events such as p53 overexpression in causation of head and neck ca...