Rafal Krela

Rafal Krela
Czech Academy of Sciences, Biology Centre · Institute of Plant Molecular Biology

Postdoctoral Researcher

About

7
Publications
15,715
Reads
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52
Citations
Introduction
I'm MSCA-ERA Fellow working on epigenetic regulation and PRC2 function in green algae. My second project is focused on nucleases connection with Acanthamoeba castellanii pathogenicity and growth. Scope of my PhD research was a involvement of plant S1-like nucleases and cross-talk with SNc nucleases during development processes and programmed cell death. I worked in EU project: "Flora Robotica | Societies of Symbiotic Robot-Plant Bio-Hybrids as Social Architectural Artifacts".
Additional affiliations
October 2014 - January 2021
Adam Mickiewicz University in Poznań
Position
  • PhD Student
Description
  • Molecular and functional characterization of nucleases involved in plant programmed cell death.
December 2014 - July 2019
Adam Mickiewicz University in Poznań
Position
  • Co-Investigator:
Description
  • Characterization of the mechanism responsible for DNA degradation in different types of plant programmed cell death.
April 2017 - March 2019
Adam Mickiewicz University in Poznań
Position
  • Researcher
Description
  • flora robotica | Societies of Symbiotic Robot-Plant Bio Hybrids as Social Architectural Artifacts (EU Horizon 2020 Grant)
Education
October 2012 - July 2014
Adam Mickiewicz University in Poznań
Field of study
  • Biotechnology
October 2009 - July 2012
Adam Mickiewicz University in Poznań
Field of study
  • Biotechnology

Publications

Publications (7)
Preprint
Epigenetic silencing is essential for regulating gene expression and cellular diversity in eukaryotes. While DNA and H3K9 methylation silence transposable elements (TEs), H3K27me3 marks deposited by the Polycomb repressive complex 2 (PRC2) silence varying proportions of TEs and genes across different lineages. Despite the major development role epi...
Article
Background S1-like nucleases are widespread enzymes commonly used in biotechnology and molecular biology. Although it is commonly believed that they are mainly Zn2+-dependent acidic enzymes, we have found that numerous members of this family deviate from this rule. Therefore, in this work, we decided to check how broad is the range of non‑zinc-dep...
Article
Background During standard gene cloning, the recombinant protein appearing in bacteria as the result of expression leakage very often inhibits cell proliferation leading to blocking of the cloning procedure. Although different approaches can reduce transgene basal expression, the recombinant proteins, which even in trace amounts inhibit bacterial...
Article
Full-text available
Biohybrid robotics takes an engineering approach to the expansion and exploitation of biological behaviors for application to automated tasks. Here we identify the construction of living buildings and infrastructure as a high-potential application domain for biohybrid robotics, and review technological advances relevant to its future development. C...
Article
Full-text available
Biohybrid consists of a living organism or cell and at least one engineered component. Designing robot–plant biohybrids is a great challenge: it requires interdisciplinary reconsideration of capabilities intimate specific to the biology of plants. Envisioned advances should improve agricultural/horticultural/social practice and could open new direc...
Article
The Coronavirus (COVID-19) Disease Pandemic, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has affected millions of people worldwide, prompting a collective effort from the global scientific community to develop a vaccine against it. This study purports to investigate the influence of factors such as sex, age, type of...
Article
Full-text available
Gamma secretase is a multi-subunit complex with aspartic intramembrane protease activity that is involved in the pathogenesis of Alzheimer’s disease in humans. In Arabidopsis thaliana, γ-secretase subunits are localized to endomembrane system compartments and interact with each other in a similar manner to their human counterparts. Here, we identif...

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