Rafael José Pérez Cambrodí

• PhD
• Managing Director at Cambrodi Ópticos

Purpose: To evaluate changes in angle kappa following the implantation of a trifocal intraocular lens (IOL), and to assess the postoperative outcomes of patients with different angle kappa values. Setting: IOA Madrid Innova Ocular, Madrid, Spain DESIGN:: Prospective trial METHODS:: Sixty-three patients due to have bilateral implantation of the d...

Purpose: To evaluate the intrasession repeatability and validity of corneal curvature measurements provided by a new multifunctional device and to assess the intrasession repeatability of its ocular aberrometric measures. Methods: This prospective study comprises 37 mild to moderate keratoconus eyes of 37 patients. In all cases, 3 repeated measu...

AIM: To evaluate the interchangeability of keratometric and asphericity measurements provided by three measurement systems based on different optical principles. METHODS: A total of 40 eyes of 40 patients with a mean age of 34.1y were included. In all cases, a corneal curvature analysis was performed with IOL-Master (IOLM), iDesign 2 (ID2), and Sir...

To review binocular and accommodative disorders documented after corneal or intraocular refractive surgery, in normal healthy prepresbyopic patients. A bibliographic revision was performed; it included works published before 1st July 2017 where accommodation and/or binocularity was assessed following any type of refractive surgical procedure. The s...

Purpose: To evaluate the differences in corneo-scleral topographic profile between healthy and keratoconus eyes, and their potential diagnostic ability for keratoconus detection. Methods: Prospective comparative study including 21 keratoconic eyes (11 patients) and 88 healthy eyes (88 patients). In all cases, a complete eye exam was performed in...

Purpose: To determine the usefulness of a silicone-hydrogel bandage contact lens (BCL) in the immediate postoperative period after uneventful myopic laser in-situ keratomileusis (LASIK). Methods: The study design was randomized but not masked and data collection was prospective. This study comprised 51 consecutive myopic eyes intervened by means...

Microperimetry (MP) is a technology that allows the study of retinal sensitivity at different foveal and parafoveal areas as well as eye fixation. It is a technique of functional evaluation, providing a direct correlation between anatomical and functional outcomes. There are a great variety of studies which evaluate the repeatability or reliability...

Purpose: To compare central corneal backscatter obtained from Scheimpflug images between patients with insulin-dependent and non-insulin-dependent diabetes mellitus (IDDM and NIDDM, respectively) and healthy controls. Methods: Seven patients with IDDM (7 eyes), eleven patients with NIDDM (11 eyes), and sixteen healthy subjects (16 eyes) were inclu...

This study evaluated the clinical outcomes in keratoconus corneas following accelerated transepithelial corneal collagen cross-linking (CXL) (Avedro KXL® system, Waltham, MA, USA) over one year of follow-up. The mean depth of the demarcation line measured by optical coherence tomography (OCT) was 205.19 µm. One month after surgery, a non-statistica...

Purpose To establish normative values of retinal sensitivity and parameters describing the fixation pattern using macular analyzer integrity assessment (MAIA) microperimetry (Centervue, Padova, Italy) in adults and children. Methods A sample of 237 eyes of 237 healthy subjects aged between 10 and 70 years (mean age 30.63 ± 16.23 years) was evaluat...

Objective To assess the clinical outcomes in ectatic corneas following accelerated transepithelial cross-linking (CXL) over 1 year of follow-up. Materials and methods Twenty-one eyes diagnosed with progressive corneal ectasia (19 keratoconus, 2 post-laser in situ keratomileusis ectasias) in 14 patients aged between 26 and 69 years were enrolled. A...

Soft multifocal simultaneous image contact lenses have boomed in recent years due to the growing number of presbyopic patients demanding visual solutions, allowing them to maintain their current standard of living. The concept of 'simultaneous image' is based on blur interpretation and/or blur tolerance of superimposed multiple images on the retina...

Introduction: Fundus autofluorescence (FAF) is a noninvasive imaging method to detect fundus endogenous fluorophores, mainly lipofuscin located in the retinal pigment epithelium (RPE). The FAF provides information about lipofuscin distribution and RPE health, and consequently an increased accumulation of lipofuscin has been correlated with ageing a...

Diabetes mellitus is a metabolic disease with a great healthcare impact owing to its increased prevalence and high mortality rate. Structural, morphological and physiological changes in each of the ocular components have been described with detail. Autofluorescence has been described as a good indicator of metabolic activity. This review aims to pr...

Purpose . Evaluate optimized fundus autofluorescence (FAF) imaging in early stages of diabetic retinopathy (DR) and relate findings with conventional colour fundus imaging and visual function in diabetic patients and control subjects. Materials and Methods . FAF and colour images were obtained using the CR-2 Plus digital nonmydriatic retinal camera...

Objective: To assess the usefulness of microperimetry (MP) as an additional objective method for characterizing the fixation pattern in nystagmus. Design: Prospective study. Participants: Fifteen eyes of 8 subjects (age, 12-80 years) with nystagmus from the Lluís Alcanyís Foundation (University of Valencia, Spain) were included. Methods: All...

Purpose . To validate clinically a new method for estimating the corneal power ( P c ) using a variable keratometric index ( n k adj ) in eyes with previous laser refractive surgery. Setting . University of Alicante and Medimar International Hospital (Oftalmar), Alicante, (Spain). Design . Retrospective case series. Methods . This retrospecti...

Purpose: We aimed to characterize the distribution of the vector parameters ocular residual astigmatism (ORA) and topography disparity (TD) in a sample of clinical and subclinical keratoconus eyes, and to evaluate their diagnostic value to discriminate between these conditions and healthy corneas. Methods: This study comprised a total of 43 kera...

The dislocation of the crystalline lens or couching technique was the predominant procedure to surgically remove cataracts until the 18th century A.D. However, in the Middle Ages, some Arab physicians tried to aspirate the opaque lens by means of a glass tube following a paracentesis. Some literary sources attributed the origins of this technique t...

Background The aim was to evaluate the visual performance achieved with a new multifocal hybrid contact lens and to compare it with that obtained with two other currently available multifocal soft contact lenses.Methods This pilot prospective comparative study comprised a total of 16 presbyopic eyes of eight patients ranging in age from 43 to 58 ye...

The purpose of this study was to evaluate intra-session repeatability of measurements of the iridocorneal angle at different meridians in the nasal and temporal areas in healthy eyes using the Sirius Scheimpflug photography-based system in glaucoma analysis mode. A total of 43 eyes of 43 patients ranging in age from 36 to 79 years were enrolled in...

To evaluate the prediction error in intraocular lens (IOL) power calculation for a rotationally asymmetric refractive multifocal IOL and the impact on this error of the optimization of the keratometric estimation of the corneal power and the prediction of the effective lens position (ELP). Retrospective study including a total of 25 eyes of 13 pati...

To evaluate the predictability of the refractive correction achieved with a positional accommodating intraocular lenses (IOL) and to develop a potential optimization of it by minimizing the error associated with the keratometric estimation of the corneal power and by developing a predictive formula for the effective lens position (ELP). Clinical da...

To evaluate the reliability and intersession agreement of measurements of retinal sensitivity as well as of the fixation pattern obtained in healthy eyes with a microperimeter integrating the mechanism of the scanning laser ophthalmoscope (SLO) with the static perimetry. This study included a sample of 44 healthy eyes of 44 subjects of a mean age o...

Purpose. To evaluate the usefulness of microperimetry in the early detection of the ocular anomalies associated with the use of hydroxychloroquine. Methods. Prospective comparative case series study comprising 14 healthy eyes of 7 patients (group A) and 14 eyes of 7 patients under treatment with hydroxychloroquine for the treatment of rheumatologic...

Diurnal changes in corneal geometry, pachymetry, and intraocular pressure (IOP) in a healthy eye were recorded. The deformation response to an air puff was simulated using 3 levels of corneal stiffness. The response was dependent on IOP and pachymetry and not only on the biomechanical properties of the cornea. Similarly, the maximum variability due...

PurposeTo evaluate the differences in endothelial cell density (ECD) and central corneal thickness (CCT) between type II diabetic patients and age-matched healthy controls, and determine the impact of time from diagnosis.Methods This is a comparative study of 77 eyes of type II diabetic patients (33 males, 44 females) and 80 eyes of healthy subject...

To explore the distribution of total, corneal, and internal higher-order aberrations (HOAs) in both insulin-dependent (IDDM) and non-insulin-dependent (NIDDM) diabetic patients. Pilot study including seven patients with IDDM (14 eyes) and 11 patients with NIDDM (22 eyes). Ocular HOAs were examined using ray tracing aberrometry (i-Trace, Tracey Tech...

Purpose: To evaluate the influence of the difference between preoperative corneal and refractive astigmatism [ocular residual astigmatism (ORA)] on outcomes obtained after laser in situ keratomileusis (LASIK) surgery for correction of myopic astigmatism using the solid-state laser technology. Methods: One hundred one consecutive eyes with myopia...

Diabetes mellitus is a metabolic disorder characterized by the presence of chronic hyperglycaemia. Several structural, morphological, and physiological changes in each of ocular component have been described in detail during the past decades. Due to these abnormalities, the diabetic patient undergoes a degradation of the retinal image by an increas...

Purpose: The aim of this study was to obtain the exact value of the keratometric index (nkexact) and to clinically validate a variable keratometric index (nkadj) that minimizes this error. Methods: The nkexact value was determined by obtaining differences (ΔPc) between keratometric corneal power (Pk) and Gaussian corneal power ((Equation is incl...

La neuritis óptica es una inflamación del nervio óptico, que puede relacionarse con diferentes condiciones sistémicas. La presentación clínica de esta patología incluye normalmente pérdida súbita de agudeza visual (AV), que puede ser unilateral o bilateral, restricción del campo visual, dolor al mover los ojos, discromatopsia -defecto pupilar afere...

Abstract We describe the case of an eight-year-old girl with complaints of headaches and blurred vision (uncorrected visual acuity: 0.1 decimal) that showed on examination miotic pupils, pseudomyopia, no ocular motility restrictions, and no associated neurological disease. After initial treatment with cyclopentolate for two months, pseudomyopia per...

The aim of this study was to analyze theoretically the errors in the central corneal power calculation in eyes with keratoconus when a keratometric index (nk) is used and to clinically confirm the errors induced by this approach. Differences (ΔPc) between central corneal power estimation with the classical nk (Pk) and with the Gaussian equation ()...

INTRODUCCIÓN El cambio de era es un tiempo de ruptura marcada por la aparición de grandes hombres de la ciencia médica que con la fortaleza de la razón, la experiencia y la independencia de pen-samiento irrumpen en un panorama plagado de compartimentos estancos. Sin embargo, no se puede negar que incluso ellos beberán en mayor o menor medida de las...

Abstract We describe a case report of a patient that was implanted with a posterior chamber phakic intraocular lens (Phakic Refractive Lens, PRL) for the correction of moderate myopia and who developed postoperatively a fixed mydriasis compatible with an Urrets-Zavalia Syndrome (UZS). Specifically, a sudden acute increase of IOP in the left eye was...

To report a very successful outcome obtained with the fitting of a new-generation hybrid contact lens of reverse geometry in a thin cornea with extreme irregularity due to the presence of a central island after unsuccessful myopic excimer laser refractive surgery. A 32-year-old man attended to our clinic complaining of very poor vision in his right...

To define a range of normality for the vectorial parameters Ocular Residual Astigmatism (ORA) and topography disparity (TD) and to evaluate their relationship with visual, refractive, anterior and posterior corneal curvature, pachymetric and corneal volume data in normal healthy eyes. This study comprised a total of 101 consecutive normal healthy e...

Roman seals associated with collyria (Latin expression for eye drops /washes and lotions for eye maintenance) provide valuable information about eye care in the antiquity. These small, usually stone-made pieces bore engravings with the names of eye doctors and also the collyria used to treat eye diseases. The collyria seals have been found all over...

Purpose To report the successful outcome obtained after fitting a new hybrid contact lens in a cornea with an area of donor-host misalignment and significant levels of irregular astigmatism after penetrating keratoplasty (PKP). Materials and methods A 41-year-old female with bilateral asymmetric keratoconus underwent PKP in her left eye due to the...

Purpose: To examine the biometric characteristics of the anterior segment in a group of Sahrawi children. Methods: A total of 66 children (33 male and 33 female, aged between 8 and 13 years) participated in this prospective, observational study. The non-invasive Pentacam Scheimpflug imaging device was used to measure corneal thickness (CT) (at the...

Purpose: To examine a single-optic accommodating intraocular lens (IOL) visual performance by correlating IOL implanted eyes’ defocus curve with the intraocular aberrometric profile and the impact on the quality of life (QOL). Methods: Prospective consecutive case series study including a total of 25 eyes of 14 patients with ages ranging between 52...

Implantation of phakic intraocular lenses (pIOLs) is a reversible refractive procedure, preserving the patient's accommodative function with minimal induction of higher order aberrations compared with corneal photoablative procedures. Despite this, as an intraocular procedure, it has potential risks such as cataracts, chronic uveitis, pupil ovaliza...

Background: To evaluate and report the visual, refractive, and aberrometric outcomes of LASIK for the correction of low to moderate hyperopia in a pilot group using a commercially available solid-state laser Methods: Prospective pilot study including 11 consecutive eyes with low to moderate hyperopia of six patients undergoing LASIK surgery usin...

Purpose: To analyze by spectral-domain optical coherence tomography the anatomical relationship of a specific type of posterior chamber phakic intraocular lens (pIOL) implanted in cases of high to moderate myopia with the adjacent intraocular structures and to correlate it with clinical outcomes. Methods: Prospective observational case series inclu...

Purpose To evaluate visual, optical, and quality of life (QoL) outcomes and intercorrelations after bilateral implantation of posterior chamber phakic intraocular lenses. Methods Twenty eyes with high to moderate myopia of 10 patients that underwent PRL implantation (Phakic Refractive Lens, Carl Zeiss Meditec AG) were examined. Refraction, visual a...

RESUMEN Los sellos romanos asociados a colirios proporcionan una información muy valiosa acerca de los Oftalmología en la antigüedad. Son pequeñas piezas, normalmente de piedra, que están graba-das con los nombres de los oculistas y los remedios que se usaban para el tratamiento de algunas enfermedades oculares. Los sellos de colirios han sido hall...

To evaluate and report the visual, refractive, and aberrometry outcomes of laser in situ keratomileusis (LASIK) to correct low to moderate myopia using a commercial solid-state laser. Oftalmar, Medimar International Hospital, Alicante, Spain. Prospective case series. This study evaluated consecutive eyes with low to moderate myopia that had LASIK p...

Instituciones: (1) OFTALMAR (Hospital Internacional Medimar). (2) GIO (Grupo de Investigación en Optometría). (3) FUNCAVIS (Fundación para la Calidad Visual). Caracterización clínica de la lente fáquica de cámara posterior PRL ® para alta y moderada miopía Comunicación Oral Antecedentes y objetivos Las lentes fáquicas de cámara posterior constituye...

To examine the visual performance of a rotationally asymmetric multifocal intraocular lens (IOL) by correlating the defocus curve of the IOL-implanted eye with the intraocular aberrometric profile and impact on the quality of life. A prospective, consecutive, case series study including 26 eyes from 13 patients aged between 50 and 83 years (mean: 6...

  The aim was to assess visual performance after PureVision high addition multifocal contact lens (PM) fitting through contrast sensitivity measured under different illumination levels for both distance and near.   In a cross-over study, 20 presbyopic patients were randomly assigned to PM or spectacles. Near contrast sensitivity was measured with t...

To evaluate the medium-term refractive and visual outcomes and the complications after implantation of a silicone posterior chamber phakic intraocular lens (PC pIOL) for moderate to high myopia. Oftalmar, Medimar International Hospital, Alicante, Spain. Retrospective case series. Uncorrected (UDVA) and corrected (CDVA) distance visual acuities, ref...

To evaluate the clinical impact and possible causes of a spontaneous decentration of a phakic refractive lens (PRL) implanted in a highly myopic eye, and analyzing the visual, refractive, and aberrometric outcome as well as the possible causes for this phenomenon. The description of a case of bilateral high myopia corrected by implantation with the...

Introducción Las lentes de contacto mejoran significativa-mente la calidad de vida de niños y adolescentes en la medida en que permiten una mejor estética y por lo tanto un menor rechazo a la corrección refractiva (1,2). Sin embargo, no sólo la estética sino también determinados factores funcionales obligan a considerar esta opción terapéutica. De...

Epigrafía funeraria oftalmológica en la Hispania romana PÉREZ-CAMBRODÍ RJ 1 , ALZAMORA-RODRÍGUEZ A 2 RESUMEN La epigrafía nos ha proporcionado un inmenso caudal de información acerca de la identidad de aquellos que practicaron la Oftalmología en época romana, de su extracción social y su origen. En el ámbito de la antigua Hispania romana son tres,...

RESUMEN. La desviación vertical disociada (DVD) es un transtorno oculomotor de origen supranuclear y cortical caracterizado por un movimiento lento e involuntario de elevación del ojo que se produce ante determinados estímulos. Junto a este movimiento de elevación se objetiva un movimiento de exodesviación y de exciclotorsión y por lo tanto un mov...