Rafael Del Caño Ochoa

Rafael Del Caño Ochoa
University of California, San Diego | UCSD · Department of Nanoengineering

Ph. D. in Chemistry
Working on the development of new electrochemical biosensors

About

12
Publications
599
Reads
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107
Citations
Citations since 2016
12 Research Items
107 Citations
201620172018201920202021202201020304050
201620172018201920202021202201020304050
201620172018201920202021202201020304050
201620172018201920202021202201020304050
Additional affiliations
July 2020 - January 2022
Universidad Autónoma de Madrid
Position
  • PhD
November 2015 - July 2020
University of Cordoba (Spain)
Position
  • PhD Student
January 2014 - November 2015
University of Cordoba (Spain)
Position
  • Master's Student
Education
November 2015 - June 2019
University of Cordoba (Spain)
Field of study
  • Physical Chemistry
September 2014 - July 2015
University of Cordoba (Spain)
Field of study
  • Chemistry
September 2010 - June 2014
University of Cordoba (Spain)
Field of study
  • Chemistry

Publications

Publications (12)
Article
Sweat is an important biofluid presents in the body since it regulates the internal body temperature, and it is relatively easy to access on the skin unlike other biofluids and contains several biomarkers that are also present in the blood. Although sweat sensing devices have recently displayed tremendous progress, most of the emerging devices prim...
Article
The interest in ketone bodies (KBs) has intensified recently as they play significant roles in healthcare, nutrition, and wellness applications. We present a disposable electrochemical sensing strip for rapid decentralized detection of β-hydroxybutyrate (HB), one of the dominant physiological KBs, in saliva. The new salivary enzymatic HB sensor str...
Article
The development of a non-invasive sensing technology that allows collection of interstitial fluid (ISF) (Reviewer 1 Comment #1) lactate and its subsequent analysis without exertion requirement, could enable lactate monitoring from rested individuals. Here, we describe a wearable, soft epidermal adhesive patch that integrates a reverse iontophoretic...
Article
The development of DNA-sensing platforms based on new synthetized Methylene Blue functionalized carbon nanodots combined with different shape gold nanostructures (AuNs), as a new pathway to develop a selective and sensitive methodology for SARS-CoV-2 detection is presented. A mixture of gold nanoparticles and gold nanotriangles have been synthetize...
Article
Full-text available
In this work we present a powerful, affordable, and portable biosensor to develop Point of care (POC) SARS-CoV-2 virus detection. It is constructed from a fast, low cost, portable and electronically automatized potentiostat that controls the potential applied to a disposable screen-printed electrochemical platform and the current response. The pote...
Article
This work focuses on the development of an electrochemiluminescent nanostructured DNA biosensor for SARS-CoV-2 detection. Gold nanomaterials (AuNMs), specifically, a mixture of gold nanotriangles (AuNTs) and gold nanoparticles (AuNPs), are used to modified disposable electrodes that serve as an improved nanostructured electrochemiluminescent platfo...
Article
Full-text available
Gold nanotriangles (AuNTs) functionalized with dithiolated oligonucleotides have been employed to develop an amplification-free electrochemical biosensor for SARS-CoV-2 in patient samples. Gold nanotriangles, prepared through a seed-mediated growth method and exhaustively characterized by different techniques, serve as an improved electrochemical p...
Article
This work focuses on the combination of molybdenum disulfide (MoS2) and à la carte functionalized carbon nanodots (CNDs) for the development of DNA biosensors for selective and sensitive detection of pathogens. MoS2 flakes prepared through liquid-phase exfoliation, serves as platform for thiolated DNA probe immobilization, while thionine functional...
Article
The highly packed cetyltrimethylammonium bromide (CTAB) bilayer built up on the surface of gold nanorods (AuNRs) when synthetized by the seed-mediated procedure hampers the complete ligand exchange under experimental conditions that preserve the stability of the dispersions. In the present work, a ligand exchange protocol by using carboxy-terminate...
Article
In this work, we report on the electrochemical behavior of bioconjugates prepared with gold nanoparticles (AuNP) capped with three different molecular layers (citrate anions, 6-mercaptopurine and ω-mercaptoundecanoic acid) and the protein hemoglobin (Hb). Freshly formed bioconjugates are deposited on a glassy carbon electrode and assayed for electr...
Article
The identification of the factors that dictate the formation and physicochemical properties of protein-nanomaterial bioconjugates are important to understand their behavior in biological systems. The present work deals with the formation and characterization of bioconjugates made of the protein hemoglobin (Hb) and gold nanoparticles (AuNP) capped w...
Poster
Full-text available
Characterization of metalloproteins immobilised on Au nanostrcutures showing different shapes

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