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Rafael R. Castillo

Rafael R. Castillo
FAME Leaders Academy · Medicine

MD

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21
Publications
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Publications

Publications (21)
Article
Full-text available
The Philippine Society of Hypertension (PSH) took part again in the annual May Measurement Month 2019 (MMM19) blood pressure (BP) measurement campaign to raise awareness of hypertension especially in those who are not aware of their condition. The MMM19 standard protocol designed by the International Society of Hypertension was used during screenin...
Article
Full-text available
Building on the gains of May Measurement Month 2017 (MMM17), the Philippine Society of Hypertension once again took part in MMM18 to raise awareness of high blood pressure (BP) in the country and to harness opportunistic BP screening in detecting unaware hypertensive individuals and referring them for treatment. We followed the standard MMM18 proto...
Article
Increased uric acid levels have been known to be associated with different cardiovascular and renal diseases. Over the last few years, several studies have examined the role of urate-lowering therapy (ULT) in hypertension and major adverse cardiac events (MACE) and suggest a potential role of elevated serum uric acid as an independent cardiovascula...
Article
Full-text available
Background Patients 65 years old and older largely represent (>50%) hospital-admitted patients with acute coronary syndrome (ACS). Data are conflicting comparing efficacy of early routine invasive (within 48–72 hours of initial evaluation) versus conservative management of ACS in this population. Objective We aimed to determine the effectiveness o...
Preprint
Full-text available
Background: Elderly patients, 65 years old and older, largely represent (>50 %) of hospital-admitted patients with acute coronary syndrome (ACS). Data are conflicting comparing efficacy of early routine invasive (within 48-72 hours of initial evaluation) versus conservative management of ACS in this population. Objective: We aimed to determine the...
Article
Full-text available
Introduction: Raised blood pressure (BP) is the biggest contributor to mortality and disease burden worldwide and fewer than half of those with hypertension are aware of it. May Measurement Month (MMM) is a global campaign set up in 2017, to raise awareness of high BP and as a pragmatic solution to a lack of formal screening worldwide. The 2018 ca...
Article
Full-text available
Raised blood pressure is the biggest single risk factor responsible for mortality worldwide. Despite this, the majority of people with hypertension are unaware of having it, are untreated, or are on treatment but uncontrolled. May Measurement Month is a global campaign initiated by the International Society of Hypertension with the aim of raising a...
Article
Full-text available
Cardiovascular diseases remain the Philippines’ leading cause of mortality, with hypertension as a prevalent contributory risk factor. We took part in May Measurement Month 2017 (MMM17), a global initiative to raise awareness of high blood pressure (BP) and to serve as a temporary solution to the lack of screening programs worldwide. Following the...
Article
Full-text available
Takayasu arteritis (TA) is a rare, systemic; largevessel vasculitis that usually involves women of child-bearing age, causing severe vascular extremity ischemia that may necessitate revascularization. We report a case of 29-yearold female, who presented with sudden right leg pain, accompanied by paresthesia, poikilothermia, pallor, and pulselessnes...
Article
On the basis of currently available evidence, 1. We welcome the increased emphasis on out-of-office BP measurement which the ACC/AHA guidelines provide, but advise caution on the reported equivalence levels by type of measurement. 2. We support the use of risk assessment recommended in the ACC/AHA guidelines but note that the levels recommended as...
Article
Full-text available
Background: Increased blood pressure is the biggest contributor to the global burden of disease and mortality. Data suggest that less than half of the population with hypertension is aware of it. May Measurement Month was initiated to raise awareness of the importance of blood pressure and as a pragmatic interim solution to the shortfall in screen...
Article
Full-text available
-Clinical trials in heart failure have focused on the improvement in symptoms or decreases in the risk of death and other cardiovascular events. Little is known about the effect of drugs on the risk of clinical deterioration in surviving patients. -We compared the angiotensin-neprilysin inhibitor LCZ696 (400 mg daily) with the angiotensinconverting...
Article
Full-text available
AIMS: Although the focus of therapeutic intervention has been on neurohormonal pathways thought to be harmful in heart failure (HF), such as the renin-angiotensin-aldosterone system (RAAS), potentially beneficial counter-regulatory systems are also active in HF. These promote vasodilatation and natriuresis, inhibit abnormal growth, suppress the RAA...

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