Radhwan M. Hussein

• Phd
• Head of Faculty at Ahl albayt University

Type 2 diabetes mellitus (T2DM) is a major global health issue associated with chronic inflammation, which contributes to both disease progression and its complications, including cardiovascular and microvascular disorders. Key inflammatory markers such as tumor necrosis factor-alpha, interleukin-6 (IL-6), E-selectin, and P-selectin are elevated in...

Objective: To evaluate the serum levels of Procalcitonin (PCT), C-Reactive Protein (CRP), Cystatin C, and Kidney Injury Molecule-1 (KIM-1) in patients with diabetic foot ulcers (DFU). Methods: This case-control study included 120 participants divided into four groups: 30 with diabetic foot ulcers (DFU), 30 with diabetic foot ulcers and chronic kidn...

Objective: To evaluate the serum levels of Procalcitonin (PCT), C-Reactive Protein (CRP), Cystatin C, and Kidney Injury Molecule-1 (KIM-1) in patients with diabetic foot ulcers (DFU). Methods: This case-control study included 120 participants divided into four groups: 30 with diabetic foot ulcers (DFU), 30 with diabetic foot ulcers and chronic kidn...

This is a case-control study, including 120 individuals who were divided into four groups: control group, diabetes mellitus without complication group, diabetic foot ulcer group and (diabetic foot with chronic kidney disease) group .Procalcitonin, Cystatin C, Nephrin ,and Kidney injury molecule-1 were determined by using the Enzyme-linked immunosor...

Endstage renal disease (ESRD) usually comes on by diabe�c nephropathy (DN), is one of the most dreaded chronic microvascular complica�ons of diabetes. The objec�ve of this study is to provide an overview of the DN-biomarker landscape with a par�cular emphasis on new approaches that improve the sensi�vity of biomarkers for iden�fying pa�ents who wil...

Objective: The main goal was to avoid all the problems associated with usual breast cancer treatment by using 6-thioguanine as a nanostructure lipid carrier (TG-NLCS). This was accomplished by administering an effective and targeted dose of 6-thioguanine (TG) to the tumour site using a long-lasting and biodegradable delivery system. Methods: A comb...

Background: Learning, and memory impairment are important issues in human society, and memory plays an essential role in daily routine, and is the basis of education, and learning. The chemical compounds that can enhance these two behavioral phenomena do a great favor to people who suffer from intellectual disability, and memory impairments. In rec...

lupus arthritis it is a synovitis that affects two or more joints and is characterized by swelling, effusion, or pain in two or more joints that lasts at least 30 minutes in the morning. The main objectives of present study can be summarized. To study the serum levels of β-CTX in patients with lupus arthritis. Measure the effect of disease severity...

Endstage renal disease (ESRD) usually comes on by diabe�c nephropathy (DN), is one of the most dreaded chronic microvascular complica�ons of diabetes. The objec�ve of this study is to provide an overview of the DN-biomarker landscape with a par�cular emphasis on new approaches that improve the sensi�vity of biomarkers for iden�fying pa�ents who wil...

Background: Lupus erythematosus (SLE) is a disease that affects two or more joints and is characterized by inflammation, effusion, or pain that lasts at least 30 minutes in the morning. Musculoskeletal involvement is one of the most prevalent signs of SLE and can be present in up to 90% of patients. Objective: To evaluate the serum levels of vitami...

The hypoxic environment is prominently witnessed in most solid tumors and is associated with the promotion of cell proliferation, epithelial-mesenchymal transition (EMT), angiogenesis, metabolic reprogramming, therapeutic resistance, and metastasis of tumor cells. All the effects are mediated by the expression of a transcription factor hypoxia-indu...

Background: Since December 2019, a new human coronavirus outbreak has spread across various nations, causing numerous cases and deaths. COVID-19 is a disease caused by the brand-new SARS-CoV-2 virus (a brand-new stress of coronavirus). Wuhan, Hubei Province, People's Republic of China, is a ten-million-person metropolis. The cornerstone and most im...

Theoretical/experimental measurement and optimization of solubility is considered as an active field of research in different scientific areas such as pharmaceutics. Novel orally administered therapeutic medicines have recently suffered from low solubility and bioavailability. Therefore, finding better methods to improve the drug solubility and bio...

Chemotherapy is among the most crucial therapeutic options for advanced hepatocellular cancer (HCC). There are side effects associated with chemotherapy drug use in cancer patients. It has been shown in animal models that the consumption of omega-3 fatty acids can be effective in reducing the side effects. The purpose of this study is to assess the...

Chemotherapy is among the most crucial therapeutic options for advanced hepatocellular cancer (HCC). There are side effects associated with chemotherapy drug use in cancer patients. It has been shown in animal models that the consumption of omega-3 fatty acids can be effective in reducing the side effects. The purpose of this study is to assess the...

Background: Polycystic ovarian syndrome (PCOS) is a common endocrine condition, occurs in about 5% to 10% of women and is thought to be caused by a hypothalamic disorder, In some women with PCOS especially obese one has hyper secretion of insulin with insulin resistance, the aim of study: To determine oocyte number and quality and ICSI outcome in i...

Objective: Hair is the human body's major esthetic display component, especially in cultural and social interactions. Alopecia starts to be diagnosed medically at a level that about 25 to 40 percent of the person's hair is dropped. Throughout this research, the potency of topical pentoxifylline in stimulating regrowth in hair loss caused by cycloph...

This work aimed to describe the anatomical and histological structure of tongue hamster papillae. For this purpose, a total of 10 adult male hamsters, Mesocrictus auatus were obtained. Based on the results, the keratinized stratified squamous epithelial is formed on the dorsal surface of the tongue. The results revealed filiform papillae projected...

Introduction: Gentamicin is a member of antibiotic group (aminoglycosides), it's very effective in the management of many gram negative bacterial infections but its nephrotoxic effect is considered the major limiting factor. The protective role of Atorvastatin against this adverse effect in male rats was investigated in this study. Materials and me...

Ovarian cancer is the fifth leading cause of death from cancer among North American women, and Ovarian cancer is one of the most common reproductive cancers and has the highest mortality rate amongst gynecologic cancers. Aim: To discover new biomarkers of ovarian cancer in order to surmount the obstacles in early-stage diagnosis. Method:The present...

Ovarian cancer is the fifth leading cause of death from cancer among North American women, and Ovarian cancer is one of the most common reproductive cancers and has the highest mortality rate amongst gynecologic cancers. Aim: To discover new biomarkers of ovarian cancer in order to surmount the obstacles in early-stage diagnosis. Method:The present...

Beta thalassemia is a genetic disorder, characterized by the complete absence or decrease synthesis of β β β β β globin chains. Regular blood transfusion is the mainstay of treatment of severe β β β β β thalassemia. Iron overload is the result of repeated blood transfusion with many complications including endocrinopathies, behavioral and neurotic...

Type 2 diabetes mellitus is a widespread health issue where resistance to insulin action can result in increased blood level of glucose. In last decades, the prevalence of Type 2 diabetes mellitus has dramatically elevated. Several research groups had reported that trace elements like iron and copper may be involved in diabetes mellitus pathophysio...

Alzheimer’s disease is the commonest form of dementia that mainly affects geriatric population. It is a complex neurodegenerative disorder that is characterized by aggregation of proteinaceous deposits within affected neurons. Associated loss of memory and deterioration of cognition can result in disability and poor quality of life. Pathogenesis of...

The study was conducted on sixty psoriatic patients and thirty apparently healthy were taken as control group. Blood was collected from clinic of dermatology in Merjan Teaching Hospital and Consultative Center for Allergy and Asthma in Hilla city. The sera obtained from the blood were used to determine the effect of psoriasis on leptin, total chole...

The metabolic syndrome (MS) is one of the main public fitness issues around the world. The superiority of MS was increasing in parallel with weight problems and diabetes worldwide. Many of the various standards for the identification of MS, its most important additives are atherogenic dyslipidemia, insulin resistance, high blood pressure and abdomi...

The metabolic syndrome (MS) is one of the main public fitness issues around the world. The superiority of MS was increasing in parallel with weight problems and diabetes worldwide. Many of the various standards for the identification of MS, its most important additives are atherogenic dyslipidemia, insulin resistance, high blood pressure and abdomi...

Background: Preeclampsia (PE) is a life-threatening complication of human pregnancy that is characterized by abnormal vascular response to placentation that is associated with increased systemic vascular resistance, enhanced platelet aggregation, activation of the coagulation system, and endothelial cell dysfunction. Objective: To investigate the t...

OBJECTIVE: Preeclampsia (PE) characterizes by abnormal vascular response to placentation. So, this research is aimed to test the effect of removal of the placenta on the circulatory level of Growth arrest specific protein 6 (Gas 6) and soluble Endoglin (sEng) and their correlation with Doppler indices, maternal hemodynamic and neonatal weight. METH...

Background: Preeclampsia (PE) is a life-threatening complication of human pregnancy and a worldwide leading cause of maternal and perinatal morbidity and mortality. PE is of unknown etiology but is usually associated with raised blood pressure and proteinuria. It characterizes by abnormal vascular response to placentation that is associated with in...