R S Upendra

R S Upendra
Reva University · School of Multidisciplinary Studies (Department of Bioelectronics Engineering)

M.Tech, Ph.D LMISTE
Looking for a potential collaboration in the arear of Microalgae based bioenergy and Healthcare Informatics

About

66
Publications
39,342
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
132
Citations
Introduction
Presently working on BIO-CNG from renewable sources
Additional affiliations
August 2019 - present
Reva University
Position
  • Head Research and Innovations
Description
  • Coordination and monitoring of research activities of the School
July 2010 - May 2018
New Horizon College of Engineering
Position
  • Professor (Assistant)
Description
  • Former Sr. Asst Professor
August 2003 - September 2008
T K R College of Engineering and Technology
Position
  • Professor (Assistant)
Description
  • Used to teach Immunotechnology, Cell biology and Genetics both theory and LAB and Cancer biology to B.Tech Biotechnology graduates

Publications

Publications (66)
Chapter
This chapter elucidates the obligatory need for the academic fraternity to upskill and align with the emerging landscape of the teaching–learning processes (TLP) at Higher Educational Institutions (HEIs) across the globe. The disruptions in Education 4.0 have been accelerated by the ongoing pandemic caused by COVID-19. As a result, it is a well-app...
Article
Full-text available
The digitization of everyday life has led to an exponential increase of data volume. As a result of this, new challenges and requirements have raised. Education domain is also experiencing this. In an effort to continuously improve the learning experience, the education field has come across several technologies. Augmented Reality (AR) is one such...
Patent
Full-text available
Developing and formulating an effective herbal sanitizer gel is the need of the hour invention, especially formulating an herbal sanitizer by procuring herbs that are easily available. The proposed invention aims at formulating a unique sanitizer gel or scrubber that can be used for multiple applications such as mouth wash, nasal spray, veggie wash...
Article
Full-text available
Covid-19 is a disease caused by virus named SARC CoV type II of Corona virus family and is announced as Pandemic disease by WHO in the month of March 2020. Virus is spreading at exponential rate and causing more than 1.3 lack death globally today. Covid-19 has been announced as one of the biggest threat to the mankind in last 100 years. Antiviral d...
Article
Full-text available
The COVID-19 influenced global pandemic severely affected the market of small industries and had a deep impact on the agri economic of the farmer community across the globe. The main objective of this article is to emphasize on the influence of global pandemic with agriculture and food sector. The lockdown made ambivalent in agriculture, the point...
Patent
Full-text available
To revolutionize the learning experience, augmented reality and deep learning must be integrated together. The potential of augmented reality usage in education is still not fully explored. One of the main advantages is its ability to be utilized in conjunction with other innovative technologies and exploit their individual potentials and proper...
Patent
Full-text available
Nanotechnology can enable the treatment paradigm and offer leapfrogging opportunities to obviate concerns of water quality degradation. Water treatment plants are using conventional methods were technology advancements are emerging especially in nanotechnology. Nanomaterials play a very significant role in water treatment. Many nanomaterials have v...
Patent
Full-text available
pH measurement is a basic need of many industries. A pH meter is an electronic instrument used for measuring the pH of liquid substances. The pH meter is more useful than the other pH indicator because it gives an accurate reading. Its accuracy exactness and easy operating make it different from another method. These elements helped the experimente...
Article
Full-text available
Mankind is at global threat today due to COVID-19 disease caused by a virus known as SARS-CoV-2. WHO has reported this virus as pandemic to be a global public health emergency. As of now, there is no vaccine or curative medicine to stop this COVID-19 virus. Consequently, it is essential for individuals to boost their immunity to fight against the v...
Chapter
The filamentous fungi such as Aspergillus terreus, Aspergillus flavus, Monascus ruber, and Monascus purpureus have been well reported to produce a proven anticholesterol drug, lovastatin. Lovastatin (mevinolin) is a naturally occurring polyketide secondary metabolite present in the Chinese fermented red yeast rice known as angkak or red rice koji....
Article
he preset study aimed to optimize downstream process (DSP) conditions of fungal derived secondary metabolite named lovastatin for the submerged state fermentation (SmF) cultures of strain Aspergillus terreus-11045. A five factorial central composite design methodology (CCD) of Response Surface design Methodology (RSM) employed to enhance impactful...
Article
ABSTRACT Globally, the population is experiences increasing food consumption shifts, various diet patterns and also alterations in the entire food choices as well as the lifestyle pattern. The increasing pressure of under-nutrition and deficiency diseases in emerging countries has demonstrated the negative consequences of a dietary transformation o...
Article
Full-text available
The present study optimized the submerged fermentation conditions of Pediococcus pentosaceus Sanna 14 culture to improve bacteriocin yield by applying response surface methodology (RSM) and hybrid artificial neural networkgenetic algorithm (ANN-GA). A full factorial central composite design (CCD) of RSM was applied to assess the effect of four prin...
Patent
Full-text available
LITERARY/ DRAMATIC WORK Title of the work : AN INTEGRATED WATER PURIFICATION SYSTEM APPLYING GREEN TECHNOLOGY
Patent
In the Worldwide paddy is an important, essential, and demanding source of food. In India primary food is Rice. Majority of the Farmers are Growing Rice and still there is more demand to produce Rice. Even though extensive research work is carried out in the field of agriculture for commercial crop such as Rice, Crop yield prediction is still chall...
Patent
Full-text available
LITERARY/ DRAMATIC WORK ATTENDANCE REPORT AUTOMATION FOR ONLINE CLASSES
Article
Full-text available
Optimization of agricultural practices for enhanced crop yield is considered to be essential phenomena for the countries like India. In order to strengthen the economy and also to meet the food demand for the exponentially growing population, optimizing the agricultural practices has become necessity. In India, weather and geographical conditions a...
Chapter
Full-text available
Agriculture is the backbone of India and its produce must be optimized.The technology trio of IoT, Cloud and M achine learning can have a trending impact on agriculture domain. Each one of these technology can contribute to a great extent in increasing the agriculture productivity. M ost of the research carried out in this direction have implemente...
Article
Full-text available
Are Lactic Acid Bacteria the bugs of the millennium? These surely are one of the highly pragmatic bugs of the millennium due to their diversity of metabolism, making them the most important group of bacteria in the production of traditional and modern fermented food products, their potential use in health and disease when used as probiotics or even...
Chapter
A group of Gram-positive, non-spore forming, non-motile, non-respiring bacteria produces variety of antimicrobial compounds i.e lactic acid, acetic acid, ethanol, formic acid, fatty acids, hydrogen peroxide and bacteriocins; are considered to be Lactic acid bacteria (LAB). Due to the GRAS status and brad spectrum antibiotic nature, among the other...
Data
Pediococcus pentosaceus strain Sanna-PK14 16S ribosomal RNA gene, partial sequence GenBank: MF183113.1
Conference Paper
Full-text available
In a densely populated country like India, the most commonly inherited disorders are hemoglobinopathies including β-thalassemia and sickle cell anemia. The root cause for these disorders can be understood by studying the gene disease association of the beta globin gene (HBB) of Hemoglobin protein by checking for any change in the expression of the...
Conference Paper
Full-text available
Bacteriocins from lactic acid bacteria (LAB) confer profound food and healthcare applications such as food preservation and as next generation antibiotics due to their broad spectrum antibiotic nature. Bacteriocin applied as hybrid nano formulation is one of the potential technologies to increase the stability and physico chemical condition of the...
Data
Rhizopus oryzae 18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1 and 5.8S ribosomal RNA gene, complete sequence; and internal transcribed spacer 2, partial sequence
Article
Full-text available
Are Lactic Acid Bacteria the bugs of the millennium? These surely are one of the highly pragmatic bugs of the millennium due to their diversity of metabolism, making them the most important group of bacteria in the production of traditional and modern fermented food products, their potential use in health and disease when used as probiotics or even...
Conference Paper
Are Lactic Acid Bacteriathe bugs of the millennium? These surely are one of the highly pragmatic bugs of the millennium due to their diversity of metabolism, making them the most important group of bacteria in the production of traditional and modern fermented food products, their potential use in health and disease when used as probiotics or even...
Article
Lactic Acid Bacteria (LAB) known to produce bacteriocins; a small, ribosomally synthesized antimicrobial peptides considered as next generation antibiotics due to the broad spectrum antibiotic nature. Scanty research was reported on the isolation and screening of different LAB species with high bacteriocin yield. With this lacuna the present st...
Data
Staphylococcus sp. strain warneri 16S ribosomal RNA gene, partial sequence Isolation of Bacteriocin producing species from south Indian pickles
Data
Weissella sp. strain confusa 16S ribosomal RNA gene, partial sequence GenBank: MF480335.1
Article
Full-text available
Lactic Acid Bacteria (LAB) known to produce bacteriocins; a small, ribosomally synthesized antimicrobial peptides considered as next generation antibiotics due to the broad spectrum antibiotic nature. Scanty research was reported on the isolation and screening of different LAB species with high bacteriocin yield. With this lacuna the present study...
Conference Paper
Full-text available
Aspergillus sp. is known to produce cholesterol reducing drug-lovastatin. Lovastatin is a naturally occurring drug found in food such as red yeast rice (red rice koji or red fermented rice, red koji rice, red koji rice, anka, or ang-kak). Lovastatin (mevinolin) was the first hypocholesterolemic drug to be approved in 1987 by Food and Drug administr...
Technical Report
Full-text available
Objectives: Microalgae are unicellular photosynthetic organisms that assimilate lipids, which can be converted in to Biofuels. Microalgae help to mitigate carbon dioxide, because of their photosynthetic properties and utilize it to produce lipids. Microalgae biomass is a zero waste generation, as every part of the biomass is utilized to generate ot...
Article
Full-text available
A quinine epoxide called terreic acid a secondary metabolite produced by the fungus Aspergillus terreus, is considered to be the “next generation antibiotic” due to its broad range antibiotic specificity. The antibiotic property of terreic acid was recognized more than 60 years ago. Previously many researchers were attempted different techniques an...
Article
Full-text available
Lactic acid bacteria (LAB) are a group of Gram-positive; non-spore forming, non-motile, non-respiring, bacteria produces variety of antimicrobial compounds such as lactic acid, acetic acid, ethanol, formic acid, fatty acids, hydrogen peroxide and bacteriocins. Among them bacteriocines (a small molecular weight proteins) are in prime important due t...
Article
Full-text available
Objective: The present investigation aimed towards the strain improvement of lovastatin maximum yielding wild-type fungal strains (Aspergillus terreus-MTCC 11045, Aspergillus terreus-MTCC 11395 and Aspergillus flavus-MTCC 11396) through physical mutagenesis by applying UV random mutations. Methods: Revival of fungal cultures on PDA plates followed...
Technical Report
Full-text available
LACUNAE  Screening of new microalgae species was not reported.  No research document was found on optimization of microalgae growth conditions to enhance the yield of lipid and biomass content using Artificial Neural Network.  Scanty research was reported on production of value added products from the lipid extracted Microalgal biomass leading t...
Article
Full-text available
Fluoride is a naturally occurring element in water systems and enters food chain mostly through drinking water. The WHO permissible limit of fluoride in water is 1.0 mg/l. At < 1.0 mg/l, it inhibits dental caries, at > 1.0 mg/l causes molting of teeth, lesion of endocrine glands, thyroid, liver and other organs. At still higher concentration (3-6 m...
Article
Full-text available
Traditional oriental fermented foods namely soy sauce, miso, vinegar, red rice vinegar, pickled tofu and Ang-kak were becoming increasingly popular in different parts of India and shall be used for isolation of hypolipidemic agent, lovastatin producing representative fungi. Existing food grade (GRAS) fungi, Monascus sp were known to produce lovasta...
Article
Full-text available
Attempts were made to prepare synbiotic yoghurt-cheese having functional attributes of both prebiotics and probiotics. Firstly, the conditions for the preparation of prebiotic yoghurt were optimized in order to determine the optimal level of prebiotic ingredients - raftiline (the fat replacer), raftilose (the sugar replacer), oat fiber and honey as...
Article
Full-text available
Artificial Neural Network (ANN) is a computerized program designed to simulate the process in which the Central Nervous System (CNS) functions. In a recent time ANN being increasingly used in biotechnology and pharmaceutical research to predict the non-linear relationship between casual factors and response variables. ANN has a remarkable ability t...
Article
Full-text available
Submerged cultures (SmF) of filamentous fungi ('Aspergillus terreus, Aspergillus flavus') are widely used to produce commercially important metabolite lovastatin. Limited investigations have been made on optimization of the different nutrients and process parameters using standard optimization methods. No previous work has used statistical analysis...
Article
Full-text available
Abstract: With the inevitable depletion of world’s energy supply, there has been an increasing interest worldwide in alternative sources of energy. Unlike fossil fuels, ethanol is a renewable energy source produced through fermentation of sugars and can be used as a partial gasoline replacement. Bioethanol market is expected to reach 100 x10^9 lite...
Article
Full-text available
Aspergillus sp. is known to produce cholesterol reducing drug lovastatin. Limited investigations have been made on screening of high yielding strains from hitherto under-utilized natural sources. With this objective, in the present study, various fungal cultures (130 in number) were isolated from natural sources such as (soil from paddy fields, oys...
Poster
Full-text available
Aspergillus terreus, Aspergillus oryzae and Monascus sp are known to produce cholesterol reducing drug- Lovastatin. It is presently available only as a drug with some after-effects. Scanty research work has been reported on the production and optimization of lovastatin based fermented foods by using underutilized substrates. Hitherto, no food syste...
Article
Full-text available
Pimenta dioica is a variety of sweet pepper used as a spice and its leaves are used for traditional culinary purpose. Epiphyllum oxypetalum is a species of cactus and can be used as a substitute for digitalis. Scanty work has been reported on the phytochemical properties, assessment of nutritive value and bio-therapeutical potentials of these two i...
Conference Paper
Statins are competitive inhibitors of 3-hydroxy-3-methyl glutaryl coenzyme A reductase, the rate limiting enzyme of cholesterol biosynthesis pathway (Alberts et al., 1980). Aspergillus terreus, Aspergillus flavus are known to produce cholesterol reducing drug- Lovastatin (Novak et al., 1997). Lovastatin isolated from Aspergillus terreus was the fir...
Article
Full-text available
Low-alcoholic beverages, especially those produced from fruits, are increasing in demand and are being consumed in the form of table beverages. Present investigation features development of such new table beverages using the underutilized regional millets- finger millet (ragi) and pearl millet (bajra). Alcoholic fruit beverages (fruits wines) are c...
Conference Paper
Full-text available
Statins are fungal secondary metabolites, which inhibit 3-hydroxy-3- methylglutaryl coenzyme A (HMO-CoA) reductase (EC 1.1.1.34) as the frrst committed enzyme of cholesterol biosynthesis. Lovastatin is produced as a secondary metabolite by fungi Penicillium sp., Monascus ruber, Aspergillus terreus and Aspergillus oryzae. Aspergillus terreus appears...
Article
Full-text available
Epiphyllum oxypetalum is a species of cactus and one of the most commonly grown of the Epiphyllum species. It is one of the under-utilized resources available in the tropical regions of the globe and can be used as a substitute for digitalis. The Shoshone Indian tribe calls the night blooming Cereus "Pain in the heart" and used it for heart pain. S...
Article
Full-text available
Culturing the individual plant cells, tissues (explants) and organs in laboratory or in vitro on synthetic media (MS media) under aseptic conditions is a usual process in plant tissue culture studies. The medium is rich in nutrients, also supports the growth of variety of microorganisms especially bacteria and fungi, which causecontamination of the...
Article
Full-text available
All-spice (pimenta) is one of the under-utilized resources available in the tropical regions of the globe. It is a variety of sweet pepper used as a spice and its leaves are used for traditional culinary purpose. Researchers have studied the antioxidant potentials of the berries of the plant, but no documented work is reported on its stem, leaf and...

Questions

Questions (5)
Question
Can we add this as publication in our google scholar. Is these sequence data shall be considered as regular publication??
Question
Process optimization is a critical step in Bioprocesses to achieve enhanced yields. When multiple factors were involved than the conventional optimization methods were false positive and they may not address the nonlinear relationship between the factors studied with respect to the final yields
Many tools were in use to apply ANN-GA based optimization and validation studies in bioprocess optimization, but were found difficulty to apply and not very user friendly.
Please suggest a latest and user friendly Biosimulation tool to study the process optimization and validation applying ANN-GA?

Network

Cited By