R. Nobis-Bosch

• Dr. rer. medic
• HSD Hochschule Döpfer

Purpose The aim of this study was to prove the efficacy of supervised self-training for individuals with aphasia. Linguistic and communicative performance in structured dialogues represented the main study parameters. Method In a cross-over design for randomized matched pairs, 18 individuals with chronic aphasia were examined during 12 weeks of su...

Current diagnostics of childhood aphasia operate with only a few test instruments. In particular, there is no test that assesses communicative-pragmatic performance. The Szenario-Kids is a diagnostic instrument under development for the evaluation of multimodal communication skills of 8- to 15-year-old children suffering from aphasia. 2 parallelize...

Background: SAPS-'Sprachsystematisches Aphasiescreening'-is a novel language-systematic aphasia screening developed for the German language, which already had been positively evaluated. It offers a fast assessment of modality-specific psycholinguistic components at different levels of complexity and the derivation of impairment-based treatment foc...

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Author version, Forum Logopädie, 2021, 45(5) .

Assessing communicative-pragmatic performance in childhood aphasia is hardly possible with the currently available test instruments. However, affected children are in risk of long-term consequences regarding their communicative skills and social participation. Developed in 2015, the Szenario-Kids is a diagnostic instrument for the evaluation of mul...

In order to come to evidence-based clinical decisions speech language therapists need to draw on specific knowledge, skills and professional attitudes. The TÜBEP-ST 1.0 introduced here is an assessment tool focussing on the evaluation of basic competencies in evidence-based decision making for german speech language therapy students. The test allow...

Stem-, Spraak- en Taalpathologie

Mit der Einführung der ICF (International Classification of Functioning, Disability and Health) gewinnen kommunikativ-pragmatische Ansätze und Methoden der Unterstützten Kommunikation (UK) in der Aphasierehabilitation an Bedeutung. In der vorliegenden Untersuchung wird B.A.Bar, ein elektronisches Hilfsmittel mit Sprachausgabe, eingesetzt, welches s...

Supervised Home Training in Aphasia: Language Learning in Dialogues Highly intensive treatment is required to improve language and communication in aphasia. Supervised home training is a viable option to increase intensity of conventional, low-frequent treatment. The objective of the present study was to investigate the effi cacy of supervised home...

There is wide agreement in the literature that significant improvements in aphasia therapy can only be obtained with high frequency of treatment. Self-training of patients at home is a reasonable completion of outpatient treatment to enhance frequency, the efficacy of home training in aphasia has not been studied empirically under strict research c...

Secretory immunoglobulin A (sIgA), the predominant antibody fraction of human milk, represents a major protective factor against neonatal infection. Until now, sIgA had been identified only in the humoral fraction of human milk. For bovine milk an association between sIgA and the milk fat globule (MFG) membranes has been demonstrated. The aim of ou...

Secretory immunoglobulin A (sIgA), the predominant antibody fraction of human milk, represents a major protective factor against neonatal infection. Until now, sIgA had been identified only in the humoral fraction of human milk. The aim of this study was to assess whether in human milk sIgA is also associated with the milk fat globule (MFG). Using...

Expression of S-fimbriae is frequent in Escherichia coli strains causing sepsis and meningitis in the newborn period. We analysed the ability of human skim milk to inhibit adhesion of S-fimbriated E. coli to human buccal epithelia. Adhesion was inhibited by up to 90% using colostrum (5%) and up to 50% with mature milk (5%), indicating that this ant...

We investigated the ability of meconium, feces from human milk-fed (HMF) newborns, and feces from formula-fed (FF) newborns to inhibit adhesion of S-fimbriated E. coli to human buccal epithelial cells. S-fimbriae are a common property of E. coli strains causing sepsis and meningitis in neonates. Meconium had the highest content of neuraminic acid a...

We investigated the presence of factors in human milk that inhibit invasion of pathogenic bacteria. The effect of human milk fat globule membrane (HMFGM) components on adhesion of cloned S-fimbriated Escherichia coli to human buccal epithelial cells was analyzed. S fimbriae are a common feature of E. coli strains causing sepsis and meningitis in ne...

We investigated the ability of meconium, feces from human milk‐fed (HMF) newborns, and feces from formula‐fed (FF) newborns to inhibit adhesion of S‐fimbriated E. coli to human buccal epithelial cells. S‐fimbriae are a common property of E. coli strains causing sepsis and meningitis in neonates. Meconium had the highest content of neuraminic acid a...