Quoc Cuong Hoang

Department of health, Can tho city, Viet Nam

Đặt vấn đề: Tiêm chủng là biện pháp hữu hiệu nhất để phòng ngừa các bệnh truyền nhiễm nguy hiểm, đặc biệt là đối với trẻ dưới 1 tuổi. Tuy nhiên hiệu quả tiêm chủng phụ thuộc vào khá nhiều yếu tố, đặc biệt trong đó là kiến thức, thực hành của người chăm sóc trẻ, cụ thể là các bà mẹ. Mục tiêu nghiên cứu: 1. Xác định tỷ lệ tiêm chủng đầy đủ, đúng lịch...

Công tác quản lý chất lượng bệnh viện góp phần quan trọng giúp các bệnh viện (BV) nâng cao chất lượng dịch vụ khám, chữa bệnh tại mỗi đơn vị. Nghiên cứu cắt ngang trên 26 cơ sở khám, chữa bệnh công lập và ngoài công lập tại thành phố Cần Thơ năm 2023 với mục tiêu đánh giá thực trạng việc thực hiện “Bộ tiêu chí chất lượng bệnh viện phiên bản 2.0” củ...

Objectives We aimed to determine epidemiological characteristics and serologic markers among chronically hepatitis B virus (HBV)-infected pregnant women during the assessment of tenofovir disoproxil fumarate (TDF) prescription in Vietnam. Methods We consecutively recruited 375 pregnant women with chronic HBV (cHBV) infection at week 25±2 of pregna...

Surveillance of the SARS-CoV-2 genome has become a crucial technique in the management of COVID-19, aiding the pandemic response and supporting effective public health interventions. Typically, whole-genomic sequencing is used along with PCR-based target enrichment techniques to identify SARS-CoV-2 variants, which is a complicated and time-consumin...

This report elucidated the first two noteworthy cases of Mpox that manifested as an emerging concern in a densely populated city in Vietnam. Two male patients (22 and 27 years old) were admitted to the hospital due to the presence of small pustules on their faces, accompanied by symptoms of fatigue, drowsiness, and muscle pain. RT-PCR confirmed the...

Introduction The World Health Organization (WHO) recommends tenofovir disoproxil fumarate (TDF) for pregnant women with hepatitis B virus (HBV) presenting with HBV DNA levels of 10 ⁶ copies/mL or more to hinder mother-to-child transmission (MTCT). Moreover, it is suggested that neonates of HBV-infected mothers receive an HBV vaccine birth dose with...

Introduction: Using tenofovir disoproxil fumarate (TDF) is recommended in the 3rd trimester for pregnant women with HBV DNA ≥ 200,000 IU/mL to prevent mother-to-child transmission (MTCT) of hepatitis B virus (HBV). However, HBV DNA quantification is unavailable in many resource-limited areas worldwide, hence prophylaxis is often missed. The aim of...

Colistin is considered the last-line antibiotic against multidrug-resistant Gram-negative bacterial infections. The global dissemination of Mobile colistin resistance mcr-harboring bacteria is threatening public health. Such isolates have been detected in various reservoirs including animals, food products, the environment, and humans. From these r...

The article suggests currently relevant data on the serogroup structure and antibiotic susceptibility of Salmonella strains isolated in the southern provinces of the Socialist Republic of Vietnam. The study included 189 Salmonella strains, isolated from feces of human with acute diarrhea (86 strains) and pork samples (103 strains). Serological iden...

Viêm phổi là nguyên nhân chủ yếu đưa đến nhập viện và tử vong ở trẻ mắc nhiễm khuẩn hô hấp cấptính. Trẻ dưới 5 tuổi, đặc biệt là trẻ dưới 2 tháng, là nhóm tuổi có nguy cơ mắc bệnh và tử vong doviêm phổi cao nhất. Vi khuẩn là căn nguyên gây bệnh phổ biến nhất. Do vậy, kháng sinh đóng vai tròquan trọng và không thể thiếu trong điều trị để giảm tỷ lệ...

Tỉ lệ nhiễm vi rút viêm gan B (HBV) ở phụ nữ mang thai thay đổi theo mức độ lưu hành HBV của khu vực và quốc gia. Thai phụ nhiễm HBV được báo cáo tại Việt Nam khoảng 10 - 11%. Bên cạnh nguy cơ lây chocon, thai kỳ có thể ảnh hưởng tới diễn tiến của bệnh nhiễm HBV mạn. Viêm gan hoạt động hoặc viêm ganbùng phát có thể xảy ra khi mang thai hoặc trong t...

Đại dịch COVID – 19 diễn biến nhanh và phức tạp, nắm rõ thực trạng triển khai và đào tạo nâng cao năng lực xét nghiệm chẩn đoán SARS-CoV-2 là việc cần thiết và cấp bách thúc đẩy nhanh chẩn đoán và phát hiện ca bệnh mới. Nghiên cứu này nhằm mô tả thực trạng công tác triển khai hỗ trợ xét nghiệm chẩnđoán khẳng định SARS-CoV-2 bằng kỹ thuật RT-qPCR tạ...

Khoảng 90% trẻ sinh ra từ mẹ nhiễm HBV sẽ mang HBV mạn tính, nguy cơ diễn tiến đến viêm gan, xơgan, ung thư gan. Để phòng ngừa lây truyền mẹ - con, ngoài tiêm vắc xin đầy đủ và đúng lịch cho trẻ, mẹ có tải lượng vi rút cao cần được điều trị dự phòng kháng vi rút trong thai kỳ. Nghiên cứu này nhằm xácđịnh tỷ lệ thai phụ nhiễm HBV cần điều trị và bỏ...

We conducted a policy situation analysis in three Mekong region countries, focused on how the animal and human health systems interact to control avian influenza (AI). The study used scoping literature reviews aimed at establishing existing knowledge concerning the regulatory context. We then conducted a series of key informant interviews with nati...

COVID-19, caused by the novel coronavirus SARS-CoV-2, has put most of the world under lockdown. Despite approved vaccines, COVID-19 cases, hospitalizations, and deaths have remained on the rise. Rapid diagnosis and necessary public health measures are still key parts to contain the pandemic. Here, the colorimetric isothermal nucleic acid amplificat...

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic of pneumonia spreading around the world, leading to serious threats to public health and attracting enormous attention. There is an urgent need for sensitive diagnostic testing implementation to control and manage SARS-CoV-2 in public health laboratories...

Tình trạng nhiễm viêm gan vi rút B (HBV) trên thai phụ là vấn đề đang rất được quan tâm do 90% người bị nhiễm HBV tại Việt Nam qua đường lây truyền từ mẹ sang con. Nghiên cứu này nhằm mô tả kiến thức và thực hành phòng ngừa bệnh viêm gan vi rút B của phụ nữ mang thai nhiễm HBV tại khu vực phía Nam 2019-2020, chúng tôi tiến hành nghiên cứu mô tả cắt...

Nghiên cứu mô tả cắt ngang trên 200 hộ gia đình được thực hiện tại thành phố Bà Rịa nhằm mô tả kiếnMthức, thái độ, thực hành và một số yếu tố liên quan về bệnh tay chân miệng của phụ huynh. Qua phân tích cho thấy, phụ huynh có kiến thức khá tốt về đối tượng dễ mắc bệnh tay chân miệng nhưng lại chưa có kiến thức đầy đủ về đường lây truyền, triệu chứ...

Nghiên cứu này được thực hiện nhằm đánh giá hiệu suất phòng xét nghiệm tham gia ngoại kiểm xét nghiệm định tính và bán định lượng từ đợt I/2018 - I/2020 tại Trung tâm kiểm chuẩn chất lượng xét nghiệm y học - Đại học Y dược Thành phố Hồ Chí Minh thông qua hệ thống thang điểm đánh giá của UK NEQAS. Kết quả cho thấy, số phòng xét nghiệm (PXN) tham gia...

Hand, foot and mouth disease is a common viral infectious disease caused by enteroviruses, including coxsackie A16 (CVA16) and enterovirus 71 (EV71). HFMD can cause severe symptoms in children which can be fatal. Human scavenger receptor class B member 2 (SCARB2) is a cellular receptor for EV71 and CVA16, providing a potential approach for preventi...

Background: Scarce information exists about immunity to hand, foot, and mouth disease (HFMD) among household contacts of index cases in Vietnam and what that means for reducing ongoing HFMD transmission in the community. Methods: We analyzed neutralizing antibodies (NT) and the incidence of enterovirus (EVs) infection among household contacts of...

Background: There is a shortage of chemical reagents for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnosis and a surge of SARS-CoV-2 cases, especially in limited-resource settings. Therefore, the combination of an optimal assay kit is necessary. Methods: We compared the ability to screen SARS-CoV-2 among three primer-probe s...

Background: The shortage of chemical reagents for severe acute respiratory syndrome - coronavirus 2 (SARS-CoV-2) diagnosis and the surge of SARS-CoV-2 cases, especially in limited-resource settings. Therefore, the combination of an optimal assay kit is necessary. Methods: We compared the ability to screen SARS-CoV-2 among three primer-probe sets ad...

The COVID-19, caused by the novel coronavirus SARS-CoV-2, has broken out of control all over the globe and put the majority of the world under lockdown. There have been no specific antiviral medications for SARS-CoV-2 while vaccines are still under development. Thus, rapid diagnosis and necessary public health measures are currently key parts to co...

Background: Little is known about risk factors for sick building symptoms (SBS) among health care workers (HCWs) who often face the workload, exposure to chemicals, and biological contaminants in the workplace. This study aims to evaluate the correlation between SBS and the symptoms among HCWs. Methods: A total of 207 HCWs were recruited in a la...

Hand, foot and mouth disease (HFMD) is an emerging infection with pandemic potential. Knowledge of neutralizing antibody responses among its pathogens is essential to inform vaccine development and epidemiologic research. We used 120 paired-plasma samples collected at enrollment and >7 days after the onset of illness from HFMD patients infected wit...

Background: The situation of renal impairment among HIV-infected patients treated with TDF-based antiretroviral (ARV) regimen greater than 3 years is little known when TDF use has been promptly increasing in Vietnam. Methods: We analyse demographic and clinical data from a cross-sectional survey of 400 HIV-infected patients aged ≥18 years, who w...

In recent years, serosurveillance has gained momentum as a way of determining disease transmission and immunity in populations, particularly with respect to vaccine-preventable diseases. At the end of 2017, the Oxford University Clinical Research Unit and the National Institute of Hygiene and Epidemiology held a meeting in Vietnam with national pol...

Introduction: When Viet Nam launched the Expanded Programme on Immunization in 1981, it covered six vaccines, including measles. Subsequently, Viet Nam experienced a marked reduction in measles infections. A nationwide measles epidemic occurred in April 2014 and an investigation found that 86% of affected children aged 9 months to 10 years were not...

Background: Hand, foot and mouth disease (HFMD) has emerged as a major public health issue in Vietnam since 2003. We aimed to investigate the household transmission of HFMD and its causative viruses from 150 households in a high incidence province in Vietnam. Methods: A longitudinal study was conducted in patients presenting to the provincial ho...

Background: Acinetobacter baumannii (Ab) is an opportunistic bacterial pathogen found in hospital-acquired infections including nosocomial pneumonia, especially multidrug-resistant Ab. This study aims to survey the drug resistance profiles of Ab isolated from patients in Thong Nhat Dong Nai General Hospital and assess the relationship between geno...

Carbapenemase-producing Enterobacteriaceae (CPE) are well known to cause many serious infections resulting in increasing mortality rate, treatment cost, and prolonged hospitalization. Among the widely recognized types of carbapenemases, New Delhi β -lactamase (NDM) and Klebsiella pneumoniae carbapenemase (KPC) are the most important enzymes. Howeve...

Dengue has been estimated to cause a substantial health and economic burden in Vietnam. The most recent studies have estimated that it is responsible for 39 884 disability-adjusted life years (DALYs) annually, representing an economic burden of US$94.87 million per year (in 2016 prices). However, there are alternative burden estimates that are nota...

Background: After new analysis, Sanofi Pasteur now recommends their dengue vaccine (Dengvaxia) should only be given to individuals previously infected with dengue and the World Health Organization's recommendations regarding its use are currently being revised. As a result, the potential costs of performing large-scale individual dengue screening a...

Background: Enterovirus A71 (EV-A71) is the major cause of severe hand, foot and mouth disease and viral encephalitis in children across the Asia-Pacific region, including in Vietnam which has experienced a high burden of disease in recent years. Multiple subgenogroups (C1, C4, C5 and B5) concurrently circulate in the region with a large variation...

The Hand, Foot and Mouth Disease (HFMD) outbreaks occurred throughout Daklak province, Vietnam in 2011. This study reviewed all 744 medical records of HFMD patients admitted to Daklak Hospital in 2011 to describe the clinical characteristics of HFMD patients and determined factors associated with severe illness. Among 744 patients, 63 (8.5%) cases...

Nowadays Progressive weight loss, common reduces performance and quality of life in patients with advanced lung cancer. However, there is a paucity of studies that focus on nutritional status and quality of life of non-small cell lung cancer (NSCLC) patients. The present study seeks to determine the nutritional status, and its relation to quality o...

Author Summary All four serotypes of dengue have circulated endemically throughout Southeast Asia for decades. However, despite the enormous burden of disease, there remains poor understanding of the similarity in disease patterns across the region. We analyzed data from over 100,000 cases of dengue from two of the largest cities in the region, Ban...

Monthly temperature and rainfall for the two cities. A. Comparison of mean temperature between two cities. B. Comparison of monthly rainfall between two cities (TIF)

Tau clustering statistic results when only cases geocoded with ‘ROOFTOP’ accuracy (the most accurate) are used versus when ‘RANGE INTERPOLATED’ and ‘GEOMETRIC CENTER’ are also used. (TIF)

Uncertainty in the force of infection estimates using profile likelihoods. (TIF)

Estimator for Tau statistic (DOCX)

Tau clustering statistic by individual year (2010–2013). (TIF)

Sensitivity analyses assuming that 0% (baseline scenario), 10% or 20% of hospitalized cases were as a result of primary infections with the remainder as a result of secondary infections. The panels set out the probability density function of the ages of cases under the different models. (TIF)

Sensitivity analysis using all cases, including both dengue fever and dengue hemorrhagic fever cases. The baseline model uses only dengue hemorrhagic fever cases. The panels set out the probability density function of the ages of cases under the different models. (TIF)

Distance comparison between geocoded address and real GPS (DOCX)

Sensitivity exploring impact of removing different years from the dataset (DOCX)

Background In 2011, a large outbreak of hand, foot and mouth disease (HFMD) in Vietnam resulted in 113,121 children seeking medical attention, of whom170 died. Understanding the epidemiology of fatal HFMD may improve treatment and help targeting prevention activities for vulnerable populations. We describe epidemiological and clinical characteristi...

An improved understanding of heterogeneities in dengue virus transmission might provide insights into biological and ecologic drivers and facilitate predictions of the magnitude, timing, and location of future dengue epidemics. To investigate dengue dynamics in urban Ho Chi Minh City and neighboring rural provinces in Vietnam, we analyzed a 10-year...

Dengue in southern Vietnam, 2001–2010. Time series of incidence, by province. Wavelet analysis of periodicity, by province; and spatial synchrony in magnitude and timing of annual dengue epidemics, at district and province levels.

Background: The prevalence of HIV and sexually transmitted infections among men who have sex with men (MSM) has increased substantially in Vietnam. This study aimed to estimate the prevalence of HIV, syphilis, urethral gonorrhoea, and urethral chlamydia, and determined correlates of HIV infection among MSM in An Giang, Vietnam. Methods: A group...

Background/Question/Methods Hand Foot and Mouth Disease has become an increasingly important emerging infection across South East Asia over the last decade. Highly episodic dynamics can result from periodic introductions of novel strains or from complex nonlinear dynamics. Disentangling these potential causes for observed dynamics requires sophis...

An estimated 2.4 billion people live in areas at risk of dengue transmission, therefore the factors determining the establishment of endemic dengue in areas where transmission suitability is marginal is of considerable importance. Hanoi, Vietnam is such an area, and following a large dengue outbreak in 2009, we set out to determine if dengue is eme...

E ´ valuation de la duré e de vie des marquages sur l'ongle pendant les vaccinations polio au Tchad Ré sumé Au Tchad, il est difficile, en interrogeant les mères, de déterminer la couverture vaccinale polio après les activités vaccinales supplémentaires (AVS) menées dans le pays. Selon l'OMS, le marquage a ` l'encre indélébile sur l'ongle des doigt...