Quentin Palomar

Quentin Palomar
Uppsala University | UU · Department of Engineering Sciences

PhD in Molecular Chemistry and Molecular Physics

About

7
Publications
696
Reads
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115
Citations
Additional affiliations
April 2018 - present
Uppsala University
Position
  • PostDoc Position
October 2014 - October 2017
Université Grenoble Alpes
Position
  • PhD Student
October 2014 - present
Université Grenoble Alpes
Position
  • PhD Student
Education
September 2012 - July 2014
University Joseph Fourier - Grenoble 1
Field of study
  • Nanochemistry and Nano- Objects
September 2009 - July 2012
University Joseph Fourier - Grenoble 1
Field of study
  • Chemistry and Chemical Processes

Publications

Publications (7)
Article
Full-text available
Accurate, robust, and rapid diagnostics is the basis for all well-functioning healthcare. There is a large need in point-of-care biosensors to facilitate diagnosis and reduce the need for cumbersome laboratory equipment. Proteases are key virulence factors in periodontitis. Periodontal disease is very common and characterized by inflammation and in...
Article
Full-text available
Matrix Metalloproteinase-7 (MMP-7) is a proteolytic enzyme overexpressed in different pathological conditions, including cancer, infection, and cardiovascular diseases, and is a relevant diagnostic biomarker and potential drug target. Here we demonstrate rapid and selective detection of MMP-7 with a limit-of-detection of 6 pg/mL and a dynamic range...
Article
Full-text available
A homemade gold electrode is modified with a carbon nanotubes/gold nanoparticles nanocomposite to perform selective and sensitive electrochemical detection of dengue toxin. This nanostructured composite offers a large specific surface and a reactive interface allowing the immobilization of biological material. Dengue antibodies are immobilized on g...
Article
WS2 nanotubes functionalized with carboxylic acid functions (WS2-COOH) were used for improved immobilization of the enzyme tyrosinase in order to form an electrochemical biosensor towards catechol and dopamine. The nanotubes were deposited on glassy carbon electrodes using a dispersion-filtration-transfer procedure to assure the reproducibility of...
Article
A high performance impedimetric immunosensor for the dengue virus antibody detection is presented. The setup profits from the formation of controlled and reproducible carbon nanotube (CNT) deposits on electrodes. Their easy functionalization via electrogeneration of a polypyrrole-NHS (N-hydroxysuccinimido 11-(pyrrol-1-yl) undecanoate) film enables...
Thesis
Le but principal de ces travaux de thèse fut la conception et la réalisation de biocapteurs par utilisation de méthodes de transduction sans marquage, comme la spectroscopie d’impédance électrochimique (EIS), pour la détection de cible d’intérêts. Pour cela, différentes architectures moléculaires, spécifiques à la molécule d’intérêt ciblée, ont été...
Article
An original impedimetric immunosensor was developed based on carbon nanotube (CNT) deposits with controlled thicknesses for enhanced electroactive surface areas leading to improved sensor performances. Cholera monitoring was chosen as the model immune system for this setup. These CNT deposits were characterized using confocal laser microscopy and e...

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Projects

Projects (2)
Archived project
An original impedimetric immunosensor was developed based on carbon nanotube (CNT) deposits with controlled thicknesses for enhanced electroactive surface areas leading to improved sensor performances. Cholera monitoring was chosen as the model immune system for this setup. These CNT deposits were characterized using confocal laser microscopy and electrochemical methods. To form the sensor device, the CNT deposits were functionalized via electrocoating of polypyrrole-nitrilotriacetic acid followed by the formation of a Cu (II) complex with the NTA functions. The bioreceptor unit, cholera toxin B Subunit, modified with biotin entities, was then immobilized via coordination of the biotin groups with the NTA-Cu(II) complex. Each step of the formation of the immunosensor and the subsequent binding of the analyte antibody anti-cholera toxin were investigated with cyclic voltammetry and electrochemical impedance spectroscopy. After optimization, the resulting impedimetric cholera sensor shows excellent reproducibility, increased sensitivities, a very satisfying detection limit of 10-13 g mL-1 and an exceptional linear range for anti-cholera detection of 8 orders of magnitude (10-13-10-5 g mL-1) and a sensitivity of 24.7 ± 0.4 Ω per order of magnitude.
Archived project
An immunosensor for the detection of dengue virus antibodies is developed by combining the advantages of a controlled formation of a carbon nanotube (CNT) film and the properties of an electrogenerated film of polypyrrole-NHS (N-hydroxysuccinimido 11-(pyrrol-1-yl) undecanoate).