Quentin Lenoble

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Verified

Quentin verified their affiliation via an institutional email.

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• PhD - HDR Neurosciences
• Assistant prof at University of Lille

Background/Objectives Glaucoma can impact the ability to perform daily life activities such as driving. In such tasks, reaction time is critical to detect hazards. Understanding the modalities that affect response times is thus essential for clinical care. Subjects/Method Simple reaction time tasks, in which participants respond as fast as possibl...

Background Most of the data on visual functions in Leber hereditary optic neuropathy (LHON) is based on patient questionnaires. Our study assessed the impact of LHON on visual function by testing facial recognition and execution of purposeful actions. Methods Twelve participants with LHON with central scotoma ranging from 5° to 20° and 12 unaffect...

Background: As the elderly population is growing worldwide and communication is increasingly relayed by visual interfaces, identifying age-related changes in the visual perception of complex stimuli is critical. We examined the effect of spatial frequency filtering on object categorization in young (mean 25 years) and older (mean 65 years) partici...

Objective : To investigate neurophysiological dynamics during a visuocognitive task in glaucoma patients vs. healthy controls. Methods : Fifteen patients with early-stage primary open-angle glaucoma (POAG) and fifteen age-matched healthy participants underwent a “go/no-go” task, monitored with EEG. Participants had to semantically categorize visual...

Significance: To better understand the implication of a potential cognitive change in glaucoma, patients were stimulated in central visual areas considered functionally normal to discard an effect due to the loss of vision during an attentional task. The outcome might improve the follow-up on the impact of the pathology. Purpose: This study aime...

While research has consistently demonstrated how autobiographical memory triggers visual exploration, prior studies did not investigate gender differences in this domain. We thus compared eye movement between women and men while performing an autobiographical retrieval task. We invited 35 women and 35 men to retrieve autobiographical memories while...

Rapid analysis of low spatial frequencies (LSFs) in the brain conveys the global shape of the object and allows for rapid expectations about the visual input. Evidence has suggested that LSF processing differs as a function of the semantic category to identify. The present study sought to specify the neural dynamics of the LSF contribution to the r...

Clinical relevance: Peripheral vision is known to be critical for spatial navigation. However, visual cognition, which impacts peripheral vision, has not been studied extensively in glaucoma. Background: Spatial memory was assessed with a known to induce a robust memory distortion called "boundary extension" in which participants erroneously rem...

Background: There is a recent interest in pupil dilation during the retrieval of autobiographical memory. We pursued this line of research by measuring pupil diameter during the retrieval of self-defining memories, that is, memories that are highly vivid, emotionally intense, and are retrieved to reflect enduring concerns in a person's life. Meth...

Background Visual perspective during memory retrieval has mainly been evaluated with methodologies based on introspection and subjective reports. The current study investigates whether visual perspective can be evaluated with a physiological measurement: pupil dilation.Methods While their pupil diameter was measured with an eye-tracker, forty-five...

The authors investigated the influence of spatial frequencies in foveal vision in glaucomatous patients in a recognition task of facial expressions. Nineteen patients, 16 age-matched and 14 young controls saw centrally presented photographs of faces. Participants categorized the facial expressions as happy, angry or neutral. Two versions were teste...

There has been a surge in social cognition and social neurosciences research comparing laboratory and real eye movements. Eye movements during the retrieval of autobiographical memories (i.e., personal memories) in laboratory situations are also receiving more attention. We compared eye movements during the retrieval of autobiographical memories us...

Purpose To estimate the impact of glaucoma on computer use and assess specific adaptations of the graphical interface to this form of visual impairment. Design Prospective experimental cohort study. Participants Forty-nine participants were recruited: 16 patients with primary open-angle glaucoma (POAG, mean±SD: 62.7±5.6 years old), 17 age-matched...

Background Severe alcohol use disorder (SAUD) is associated with widespread cognitive impairments, including low‐level visual processing deficits that persist after prolonged abstinence. However, the extent and characteristics of these visual deficits remain largely undetermined, impeding the identification of their underlying mechanisms and influe...

Verbal fluency tasks are widely used as a neuropsychological test of language production. We assessed pupil dilation during a verbal fluency task and during a control task. On the verbal fluency task, we asked 45 healthy participants (mean age = 23.55 years) to generate as many words as possible beginning with the letter “P,” whereas on the control...

PRéCIS:: In a reach-and-grasp task, patients with glaucoma exhibited a motor disorder, even when they had time to explore their environment. The motor performance of glaucoma patients should be taken into account in rehabilitation. Purpose: Vision plays an important role in planning and executing manual prehension (reaching and grasping). We asse...

Background Pupil activity has been widely considered as a “summed index” of physiological activities during cognitive processing. Methodology We investigated pupil dilation during retrieval of autobiographical memory and compared pupil diameter with a control condition in which participants had to count aloud. We also measured pupil diameters retr...

Aims: The visual exploration and the ability to correctly locate a target in reaching an object are critical in daily life. We investigate the object reachability judgment in neovascular age-related macular disease (nAMD) and primary open-angle glaucoma patients (POAG). Methods: Sixty-three participants were recruited in 4 groups (15 nAMD, 15 POAG,...

Precis: The results showed that people with glaucoma are able to perform with high accuracy a context-association task on a touch screen. This device could be a new possibility for communication and for clinical assessment. Background: The present study was designed to investigate the ability of patients with glaucoma to use a touch screen to fi...

This study has developed an original approach to the relationship between eye movements and autobiographical memory, by investigating how maintained fixation could influence the characteristics of retrieved memories. We invited participants to retrieve autobiographical memories in two conditions: while fixating a cross at the centre of a screen and...

Aim: Object/background association is critical to understand the context of visual scenes but also in daily life tasks like object search. Patients with Alzheimer disease (AD) exhibit impairment in scene processing at different levels: perception, recognition, memory and spatial navigation. We explored whether patients with AD make use of contextu...

Significance: Vision is paramount for motor actions directed toward objects. Vision allows not only the identification of objects and their shape and spatial location, but also the adaptation of our movement when it arrives on the object. These findings show that vision deficits, as in age-related macular degeneration (AMD), can lead to reaching a...

We investigated eye movement during past and future thinking. Participants were invited to retrieve past events and to imagine future events while their scan path was recorded by an eye-tracker. Past thinking triggered more fixation (p < .05), and saccade counts (p < .05) than future thinking. Past and future thinking triggered a similar duration o...

This study assessed whether specific eye movement patterns are observed during emotional autobiographical retrieval. Participants were asked to retrieve positive, negative and neutral memories while their scan path was recorded by an eye-tracker. Results showed that positive and negative emotional memories triggered more fixations and saccades but...

Background/Study Context: The objective of this study was to investigate the object recognition deficit in aging. Age-related declines were examined from the presemantic account of category effects (PACE) theory perspective (Gerlach, 2009, Cognition, 111, 281–301). This view assumes that the structural similarity/dissimilarity inherent in living an...

Purpose There is evidence that people with glaucoma exhibit difficulties with some complex visual tasks such as face recognition, motion perception and scene exploration. The purpose of this study was to determine whether glaucoma affects the ability to categorise briefly presented visual objects in central vision. Methods Visual categorisation pe...

PURPOSE: There is evidence that people with glaucoma exhibit difficulties with some complex visual tasks such as face recognition, motion perception and scene exploration. The purpose of this study was to determine whether glaucoma affects the ability to categorise briefly presented visual objects in central vision. METHODS: Visual categorisation p...

Neuroimaging studies have shown that faces exhibit a central visual field bias, as compared to buildings and scenes. With a saccadic choice task, Crouzet, Kirchner, and Thorpe (2010) demonstrated a speed advantage for the detection of faces with stimuli located 8° from fixation. We used the same paradigm to examine whether the face advantage, relat...

Purpose: We investigated the visuomotor behavior of people with reduced peripheral field due to glaucoma while they accomplished natural actions. Methods: Twelve participants with glaucoma and 13 normally sighted controls were included. Participants were asked to accomplish a familiar sandwich-making task and a less familiar model-building task...

Purpose: In our modern society, many touch screen applications require hand-eye coordination to associate an icon with its specific contextual unit on phones, on computers, or in public transport. We assessed the ability of patients with age-related macular degeneration (AMD) to explore scenes and to associate a target (animal or object) with a un...

Purpose: In our modern society, many touch screen applications require the hand-eye coordination to associate an icon with its specific contextual unit on phones, on computers, or in public transport. We assessed the ability of patients with age-related macular disease (AMD) to explore scenes and to associate a target (animal or object) with a uniq...

Purpose In our modern society, many touch screen applications require the eye-hand ability to associate a target or an icon with its specific contextual unit, on phones, computers, or in public transport. We investigate the ability of patients with glaucoma to use a touch screen to find, recognize, and associate an object to a consistent background...

Atrophy of the medial temporal lobe structures that support scene perception and the binding of an object to its context (i.e., the hippocampus and the parahippocampal cortex) appears early in the course of Alzheimer's disease (AD). However, few studies have investigated scene perception in people with AD. Here, we assessed the ability to find a ta...

We investigated the performance in scene categorization of patients with Alzheimer's disease (AD) using a saccadic choice task. 24 patients with mild AD, 28 age-matched controls and 26 young people participated in the study. The participants were presented pairs of coloured photographs and were asked to make a saccadic eye movement to the picture c...

ABSTRACT Previous studies have shown that a yellow filter (CPF450) can increase contrast, motion sensitivity, vergence, and accommodation. We investigated whether a yellow filter can reduce age-related visual deficits. We tested two groups of 60 observers (mean age 24 vs. 72) in an object categorization task. Grayscale photographs of natural object...

Unlabelled: BACKGROUND/STUDY CONTEXT: The authors assessed whether age-related changes in low-level vision affects higher-level processes involved in object categorization. Methods: Thirty young and 30 older observers were asked to categorize gray levels photographs of natural and artifactual objects. The authors manipulated contrast (8% vs. 30%...

The study investigated the aging of object categorization manipulating the spatial frequency (SF) content in photographs of object and the object category. Thirty young (m = 22 years old) and 24 mature adults (m = 57 years old) categorized 120 items (animals/tools) presented for 200 ms each, in one of three versions: a normal version (no filter), a...

Functional changes in normal aging for both Magnocellular (M) and Parvocellular (P) pathways have been reported, with a greater loss for the P system (Elliot & Werner, 2010, JOV). The aim of the study was to investigate the late development of the two systems in old age by comparing two aged groups. A short version of the original paradigm (Pokorny...

The study aimed at evaluating the psychophysical correlates of the magnocellular and parvocellular visual pathways, their evolution and rehabilitation with normal aging. Thirteen young (24.2) and 36 old (71.4) participants were shown with a short version of the psychophysical paradigm (Pokorny and Smith, 1997, JOSA), to bias processing toward magno...

The study aimed at evaluating the psychophysical correlates of the magnocellular and parvocellular visual pathways, their evolution and rehabilitation with normal aging. Thirteen young (24.2) and 36 old (71.4) participants were shown with a short version of the psychophysical paradigm (Pokorny and Smith, 1997, JOSA), to bias processing toward magno...