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Quentin Fournier worked at the University of Edinburgh, before joining Fitzpatrick Referrals Oncology and Soft Tissue. Quentin does research in Veterinary Oncology.
June 2019 - September 2019
Centre Hospitalier Vétérinaire Frégis
- Head of Department
Objective: To determine the outcome of dogs with soft tissue sarcoma (STS) within the region of the ischiatic tuberosity (ITSTS) treated surgically. Study design: Multi-institutional retrospective study ANIMALS: Fifty-two client-owned dogs with histologically confirmed STS in the region of the IT treated with surgical resection between March 1st...
Canine mast cell tumours (MCTs) typically spread to lymph nodes (LNs) before reaching distant sites, and LN assessment is an important part of MCT staging. Sentinel LN (SLN) mapping techniques to identify draining LNs are being developed and could improve the accuracy of MCT staging. The primary objective of this feasibility study was to determine...
Chemotherapy‐induced diarrhea (CID) is a frequent chemotherapy adverse event in dogs. Yet, there is currently no consensus regarding its management. Smectite is a natural medical clay, widely used in the treatment of acute diarrhea in humans. The objectives of this study were to assess the efficacy of smectite in the management of CID in dogs, and...
An 8-year-old neutered female domestic shorthair cat was presented for further management of an apocrine gland cystadenocarcinoma. Extensive nodal metastasis was diagnosed and the cat was humanely destroyed 2 months after presentation. Post-mortem histopathology of the cystadenocarcinoma revealed areas of yellow–brown granular pigmentation on light...
Absolute neutrophil count (ANC) cut‐offs for antimicrobial prophylaxis in veterinary cancer chemotherapy patients are empirical and vary between institutions. Evidence based cut‐offs are vital for antimicrobial stewardship, particularly as global antimicrobial resistance rises. The primary objectives of this study were to evaluate the tolerability...
Background: Exfoliative dermatitis is a well-recognized cutaneous paraneoplastic syndrome (PNS) associated with thymoma in cats, of which the clinical and histopathological presentation has been well-characterized. Objectives: To describe a novel clinical skin manifestation associated with thymoma in a cat. Animal: A 14-year-old neutered femal...
Background Fine‐needle aspiration cytology (FNAC) of lymph nodes (LNs) is routinely used for staging canine malignant solid tumors, but studies evaluating its efficacy are limited. Objectives The primary objectives of this study were to evaluate the sensitivity/specificity of FNAC and the significance of nondiagnostic FNAC when staging canine mali...
Introduction: Mast cell tumour (MCT) nodal metastasis is challenging to diagnose cytologically. Extirpation of metastatic lymph nodes (LNs) might be therapeutically beneficial, possibly altering the correlation of nodal metastatic status with clinical outcome. This study's first aim was to investigate the correlation of cytological criteria previou...
Background: Prechemotherapy absolute neutrophil count (ANC) cutoffs are arbitrary and vary across institutions and clinicians. Similarly, subjective guidelines are utilized for the administration of prophylactic antibiotics in neutropenic dogs. Objectives: To evaluate the impact of various ANC cutoffs on chemotherapy administration in dogs with...
Signalment: 'Billy', 6.5 years old neutered male black&white Cocker Spaniel. History: Billy presented to the University of Edinburgh's Oncology Service for investigation of numerous, rapidly growing, cutaneous and subcutaneous nodules. The first nodule appeared six months earlier and in the 6 weeks before presentation multiple nodules had rapidly a...
We have been managing a complex case, an 8yo Staffordshire Bull terrier with several cancers including a lung tumour thought to be a possible biphasic pulmonary blastoma; the epithelial cell population seemed benign (MC=1/10hpf) and the spindle cell population malignant (MC = 41/10hpf).
We are not very confident how to classify the lung tumour, especially between pulmonary blastoma or pleuropulmonary blastoma.
Our lung tumour does not contain some of the features that are often described in PB and PPB:
a. A clear cambium layer beneath epithelium is not visible
b. Blastema islands, which are usually predominant in PPB, are not evident. The mesenchyme in our case looks more undifferentiated sarcomatous
c. Loose areas of mesenchyme as seen in Wilms tumour are not evident
d. Cartilage and rhabdomyomatous areas are not evident
e. Focal cellular anaplasia is not evident
The epithelium in our tumour appears better differentiated than many of the cases seen in the literature.
Would anyone be able to help? I can provide more details and try to digitalise the slides.