Queensley Adesuwa EghianruwaUniversity of Uyo | UNIUYO · Department of Biochemistry
Queensley Adesuwa Eghianruwa
PhD Molecular Biology and Biotechnology
About
10
Publications
111,130
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
59
Citations
Introduction
Queensley Adesuwa Eghianruwa currently works at the Department of Biochemistry, University of Uyo. Queensley does research in Biochemistry (Protein chemistry, Natural products chemistry and Molecular Biology).
Additional affiliations
August 2012 - present
August 2012 - present
Position
- Assistant Lecturer
Description
- I teach biochemistry to second, third and fourth year university students
March 2009 - October 2011
Position
- Msc student and research assistant
Description
- Our group was interested in studying lectins from various sources
Education
March 2016 - November 2019
Pan African University Institute of Science, Technology and Innovation
Field of study
- Moleculer Biology and Biotechnology
March 2009 - November 2011
January 2004 - March 2007
Publications
Publications (10)
Inflammation is the immune system's response to infection and injury. Although it is a natural and beneficial process, it has been implicated in the pathogeneses of arthritis, cancer, neurodegenera-tive, and cardiovascular disease. In this study, we evaluated the in vitro anti-inflammatory activity of the alcohol and aqueous extracts of marine gast...
Context:
Multifunctional food protein-derived peptides attract a great deal of research interest due to their health-promoting benefits. Particularly, peptides that have both antihypertensive and antioxidant properties are desired, since both effects can be synergistic in prevention of cardiovascular diseases.
Aim:
The aim of this study was to i...
The multifunctional nature of antioxidant peptides makes them more attractive candidates as dietary ingredients in health maintenance. Therefore, food protein-derived antioxidant peptides are continuously investigated. This study investigated the in vitro antioxidant properties of hydrolysate and ultrafiltered peptide fractions of Pachymelania auri...
Purpose and Methods
In this study, the analgesic activity of the crude alcohol (acetone-methanol) and aqueous (in PBS, pH 7.2) extracts of the marine molluscs, Pachymelania aurita and Tympanotonus fuscatus, has been evaluated using the formalin test (for chronic antinociceptive) and the tail-flick (acute antinociceptive) pain models in male swiss a...
Low molecular weight peptides are among the most active bioactive components that have been isolated from marine molluscs. Currently, peptides isolated from molluscs as well as their synthetic structural analogues are in clinical trials as anticancer compounds and have been approved for use in pain management. These Bioactive peptides have also bee...
![Fig. 2. Dolastatin 10 [44]](profile/Queensley-Eghianruwa/publication/336699347/figure/fig1/AS:816443318886401@1571666664357/Dolastatin-10-44_Q320.jpg)
Marine organisms make up approximately half of the total global biodiversity, with the Mollusca containing the second largest number of species, including snails and bivalves. The marine environment is highly competitive, hostile and aggressive, which has led to the production of specific and potent bioactive compounds by the mollusca and their ass...
This study aimed to investigate the antimitotic and antiproliferation activities of crude acetone-methanol and aqueous extracts of two marine molluscs commonly found in the Niger Delta region of Nigeria; T.fuscatus and P.aurita, against human cancerous cell lines (DU145, Hep-2, and HCC1395) cell lines in vitro. The antimitotic activity of the extra...
Aims: This study was aimed at evaluating the antimicrobial potential of the alcohol and aqueous extracts as well as peptide fractions of T. fuscatus and P. aurita. Place and Duration of Study: Methodology: The antimicrobial activity of the whole body aqueous and acetone-methanol extracts of T.fuscatus Var Radula and P.aurita, collected from the Nig...
Recent advances in natural products chemistry and phytomedicine research has been aimed at novel lipid based drug delivery systems. Herbosome technology is one of such systems that incorporate phospholipids into standardized active ingredients of herbal extracts, thus effectively enhancing the bioavailability of water-soluble bioactive constituents...
A lectin (LEL) was isolated from the fresh fruiting bodies of the shiitake mushroom Lentinula edodes by a combination of gel filtration chromatography on Sephadex G-150 and affinity chromatography on an N-acetyl-Dgalactosamine-Sepharose 4B column. Its molecular mass, as determined by gel filtration, was estimated to be 71, 000 Daltons and its struc...
Questions
Questions (5)
They say they are the number 1 academia-industry partnering network for Scientific Innovations in all fields of Life Sciences. Has anyone worked or used the services of Inospin (formerly known as Biowebspin) before? Are they legit pls?
So I want to carry out antiinflamatory studies using cell lines in which I treat the cells with LPS and then check for IL-1 beta, NO, PGE2 etc. My question is do I need to use specific cell lines for this? I have seen people use RAW 264.7, HL-60 and THL-1 cells but I do not have these cell lines at the moment. Can I use just any other cancerous and non cancerous mammalian cells?
I Have these alcohol extracts that I cannot evaporate due to low yield hence the extract is still in liquid form in the alcohol. Pls does anyone know a way I can make up different concentrations from this extract to use in an acute toxicity study involving mice?
I am currently working on isolating bioactive low molecular weight peptides. I am very new to using MALDI Tof. Please I would like to know what I can apply MALDI Tof to in studying my peptides aside from using it to determine molecular weight?
Hi
I am looking into isolating bioactive peptides from a snail species that has not been worked on so we cant tell what to expect. My question is what is a basic way to detect the presence of cyclic peptides in a methanolic extract and other fractions after solvent partitioning? Thanks
