Qiushi Liu

Qiushi Liu
University of Glasgow | UofG · Institute of Infection, Immunity and Inflammation

About

20
Publications
1,461
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31
Citations
Introduction

Publications

Publications (20)
Article
Full-text available
In Trypanosoma brucei, mitochondrial pre-mRNAs undergo 3'-5' exonucleolytic processing, 3' adenylation and uridylation, 5' pyrophosphate removal, and, often, U-insertion/deletion editing. The 3' modifications are modulated by pentatricopeptide repeat (PPR) Kinetoplast Polyadenylation Factors (KPAFs). We have shown that KPAF3 binding to the 3' regio...
Article
Full-text available
The negative effects of honey bee parasitic mites and deformed wing virus (DWV) on honey bee and colony health have been well characterized. However, the relationship between DWV and mites, particularly viral replication inside the mites, remains unclear. Furthermore, the physiological outcomes of honey bee immune responses stimulated by DWV and th...
Preprint
The negative effects of honey bee parasitic mites and deformed wing virus (DWV) on honey bee and colony health have been well characterized. However, the relationship between DWV and mites, particularly viral replication inside the mites, remains unclear. Furthermore, the physiological outcomes of honey bee immune responses stimulated by DWV and th...
Article
Full-text available
It is still not understood how honey bee parasite changes the gene expression to adapt to the host environment and how the host simultaneously responds to the parasite infection by modifying its own gene expression. To address this question, we studied a trypanosomatid, Lotmaria passim, which can be cultured in medium and inhabit the honey bee hind...
Article
Full-text available
Honey bee parasitic mites (Tropilaelaps mercedesae and Varroa destructor) detect temperature, humidity, and odor but the underlying sensory mechanisms are poorly understood. To uncover how T. mercedesae responds to environmental stimuli inside a hive, we first identified the sensilla-rich sensory organ on the foreleg tarsus. The organ appeared to c...
Data
List of genes highly expressed in the forelegs relative to main body.
Data
List of genes highly expressed in the forelegs relative to hindlegs.
Data
GO terms enriched with genes highly expressed in the forelegs compared with main bodies of T. mercedesae.
Data
GO terms enriched with genes highly expressed in the hindlegs compared with main bodies of T. mercedesae.
Data
Total reads of RNA-seq and the alignment rates to the reference genome.
Data
List of genes highly expressed in the hindlegs relative to main body.
Data
Expression of TmIR25a and TmIR93a proteins. The IR proteins (V5-epitope) and β-actin expressed in HEK293 cells transfected with empty vector (Mock), TmIR25a-, and TmIR93a-expressing constructs were analyzed by western blot. The size (kDa) of protein molecular weight marker (MW) is at the left.
Article
Full-text available
Two trypanosomatid species, Lotmaria passim and Crithidia mellificae, have been shown to parasitize honey bees to date. L. passim appears to be more prevalent than C. mellificae and specifically infects the honey bee hindgut. Although the genomic DNA has been sequenced, the effects of infection on honey bee health and colony are poorly understood....
Preprint
Full-text available
Although there are many honey bee pathogens/parasites, it is still not understood how they change their gene expression to adapt to the host environment or how the host simultaneously responds to pathogen/parasite infection by modifying its own gene expression. Such interactions must lead to changes in the physiological states of both host and para...
Preprint
Honey bee parasitic mites (Tropilaelaps mercedesae and Varroa destructor) detect temperature, humidity, and odor but the underlying sensory mechanisms are poorly understood. To uncover how T. mercedesae responds to environmental stimuli inside a hive, we identified the sensilla-rich sensory organ on the foreleg tarsus. The organ contained four type...
Preprint
Two trypanosomatid species, Lotmaria passim and Crithidia mellificae, have been shown to parasitize honey bees to date. L. passim appears to be more prevalent than C. mellificae and specifically infects the honey bee hindgut. Although the genomic DNA has been sequenced, the effects of infection on honey bee health and colony are poorly understood....

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