Qiang Lv

Qiang Lv

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200
Publications
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Publications

Publications (200)
Article
Full-text available
Background Tumour-derived exosomes have recently been shown to participate in the formation and progression of different cancer processes, including tumour microenvironment remodelling, angiogenesis, invasion, metastasis, and drug resistance. However, the function and mechanism of exosome-encapsulated nucleic acids and proteins in bladder cancer re...
Article
Aims: Patients with atrial fibrillation (AF) have an increased risk of cardiovascular events and dementia, even if anticoagulated. Hypertension is highly prevalent in AF population; however, the optimal blood pressure (BP) target for AF patients remains unknown. Methods and results: We conducted subgroup analysis of the Systolic Blood Pressure I...
Preprint
Background: Tumor-derived exosomes (TDEs) have recently been shown to participate in the formation and progression of different cancer processes, including tumor microenvironment remodeling, angiogenesis, invasion, metastasis, and drug resistance. However, the function and mechanism of exosome-encapsulated nucleic acids and proteins in bladder canc...
Article
Full-text available
Purpose The purpose of this study is to investigate the effect of asymptomatic hyperuricemia on mortality of elderly patients with coronary artery disease (CAD) after elective percutaneous coronary intervention (PCI). Methods One thousand two hundred ninety-six patients with coronary heart disease ≥65 years old who had increased uric acid records...
Article
Aims The prevalence and incidence of atrial fibrillation (AF) significantly increase with age. Catheter ablation is already recommended in the guidelines for this selected elderly population. This study aimed to explore the safety and effectiveness of AF catheter ablation in patients aged ≥80 years. Methods The data were based on the China-AF stud...
Article
Full-text available
We report a rare case of a 43-year-old woman with calcific annular constrictive pericarditis (CP) encircling the basal segment of the right ventricle and the mid-segment of the left ventricle (LV) lateral wall. Over time, localized calcification has caused LV to be tightly strangled and shaped like a gourd. However, multimodality imaging confirmed...
Article
Full-text available
Autophagy plays a critical role in cancer, since it can either suppress tumorigenesis by inhibiting cancer cell survival, or facilitate tumorigenesis by promoting cancer cell proliferation and tumor growth. However, the role of genetic variants of autophagy-regulated key genes for bladder cancer risk remained unclear. Here, we aimed to explore the...
Article
Full-text available
Background Anemia is a common comorbidity in patients with atrial fibrillation (AF). Reports on the association of anemia and adverse events in patients with AF, especially from Asia, are limited. Methods and Results Based on data from the Chinese Atrial Fibrillation Registry Study (CAFR), a total of 18,106 AF patients enrolled between August 2011...
Article
Background: Chronic kidney disease (CKD) is highly prevalent in patients with atrial fibrillation (AF). However, the association between CKD and clinical consequences in AF patients is still under debate. Methods: We included 19,079 nonvalvular AF patients with available estimated glomerular filtration rate (eGFR) values in the Chinese Atrial Fi...
Article
Full-text available
Aims: To distinguish between constrictive pericarditis (CP) and restrictive cardiomyopathy (RCM) using cardiac magnetic resonance feature tracking (CMR-FT) left ventricle (LV) diastolic time-strain curve patterns and myocardial strain. Methods and results: A total of 32 CP patients, 27 RCM patients, and 25 control subjects were examined by CMR-F...
Preprint
Full-text available
Background: Although thousands of alternative splicing related single nucleotide polymorphisms (AS-SNPs) have been uncovered in human tumors, the potential function of AS-SNPs involved in bladder cancer is rarely reported. Here we identified bladder cancer risk-associated AS-SNPs and revealed its underlying causal mechanism in bladder carcinogenesi...
Article
For high-performance microbolometric focal plane array, a pair of mutually restricted microbolometer performance parameters are analyzed and discussed. The main parameters optimization contradiction is between the microbolometric infrared signal to noise ratio and signal bandwidth, and these two performance characteristics parameters are decisive t...
Article
Full-text available
Although genome-wide association studies (GWASs) have successfully revealed many common risk variants for bladder cancer, the heritability is still largely unexplained. We hypothesized that low-frequency variants involved in bladder cancer risk could reveal the unexplained heritability. Next-generation sequencing of 113 patients and 118 controls wa...
Article
For high-temperature-resolution microbolometric focal plane arrays, the required characteristic parameter of substrate temperature fluctuation suppression is analyzed and discussed. The microbolometric temperature response to the temperature change of an infrared imaging target is theoretically derived from the microbolometer physical models of inf...
Article
Full-text available
Recently N6-Methyladenosine (m6A) has been identified to guide the interaction of RNA-binding protein hnRNP C and their target RNAs, which is termed as m6A-switches. We systematically investigated the association between genetic variants in m6A-switches and bladder cancer risk. A two-stage case-control study was performed to systematically calculat...
Article
Background Dilated cardiomyopathy (DCM) may be a result of or the cause of left bundle branch block (LBBB) in patients with DCM and LBBB. It is almost impossible from the history alone to know which came first in clinical work. Methods Patients with LBBB and DCM who had cardiac magnetic resonance (CMR) examination were analyzed. Occurrence sequenc...
Article
To increase the output signal-to-noise ratio of microbolometric focal plane array, the microbolometric bias optimization is crucial. The bias influence on the microbolometric responsivity is theoretically analyzed and numerically calculated, and the microbolometric responsivity can be optimized according to these theoretical analysis and calculated...
Article
Objectives: To evaluate the feasibility of three bladder neck reconstruction (BNR) techniques in laparoscopic radical prostatectomy (laparoscopic RP) and their effects on urinary continence. Methods: We retrospectively analyzed 121 patients with organ-confined prostate cancer who underwent laparoscopic RP in our center from March to December 201...
Article
For future high-performance microbolometric focal plane array, a new kind of CMOS readout integrated circuits is proposed in this paper. The whole readout integrated circuits consist of several or dozens of readout modules working in parallel and all the output signals of these readout modules can be output one by one by a common high-speed HCDS ou...
Article
Full-text available
Objectives This study was to assess the feasibility of a modified multiphasic CT scan protocol combined with homemade software measurements of glomerular filtration rate (CT-GFR) and explore the effect of renal tumor volume on the calculation of CT-GFR.Materials and Methods Prospective observational study comparing three methods of GFR measurement...
Article
Full-text available
Objectives: To investigate the relationship between coronary artery calcification and calcium deposition in cardiomyocytes. Methods: Patients who underwent valve replacement plus surgical ablation for atrial fibrillation, together with left atrial appendage resection, were included. Coronary artery calcification (CAC) score was evaluated prior t...
Article
For a normal microbolometric focal plane array, the microbolometric infrared responsivity varies with its substrate temperature fluctuations because of the semiconductor characteristics of the microbolometer array. The relationship between the microbolometric infrared responsivity and substrate temperature is theoretically discussed in this paper....
Article
Full-text available
Background: Wilms' tumor 1-associating protein (WTAP) plays an important role in physiological processes and the development of tumor such as cell cycle regulation. The regulation of cell cycle is mainly dependent on cyclins and cyclin-dependent protein kinases (CDKs). Recent studies have shown that CDKs are closely related to the tumor diagnosis,...
Article
Objectives To assess the feasibility of a novel functional perfusion model based on enhanced computed tomography (CT) for the evaluation of split renal function and orientation of segmental renal artery clamping during laparoscopic partial nephrectomy (LPN). Materials and Methods From December 2016 to November 2017, functional perfusion model was...
Article
Full-text available
Background: Extracellular communication within the tumor microenvironment plays a critical role in tumor progression. Although exosomes can package into long non-coding RNAs (lncRNAs) to mediate extracellular communication, the role of exosomal lncRNA PTENP1 in bladder cancer (BC) remains unclear. Method: We detected PTENP1 expression between pa...
Article
Based on the physical thermal balance equation of the microbolometer under pulse current bias, the microbolometric theoretical infrared responsivity is given out in this paper. The operating temperature of the microbolometer during the pulse current bias period is theoretically discussed and analyzed, from which the microbolometric theoretical infr...
Article
Full-text available
Objective This study was performed to assess the prevalence of nonalcoholic fatty liver (NAFL) in patients with symptomatic congestive heart failure (CHF) and compare the clinical features with those of patients without NAFL. Methods In total, 102 patients with CHF were divided into NAFL and non-NAFL groups according to their hepatic ultrasonograp...
Article
Full-text available
Background/aims: Chloroquine was formerly used as an anti-malarial agent drug but has now been proven to be useful for various diseases. This study aimed to investigate the radiosensitizing effect of chloroquine in bladder cancer, with an emphasis on autophagy inhibition and apoptosis induction. Methods: Bladder cancer cell lines were irradiated...
Article
Full-text available
Hormone therapy drugs, such as bicalutamide and enzalutamide, directed against prostate cancer focus on androgen receptor (AR) signaling and are initially effective, but the disease progresses to lethality as resistance to these drugs develops. A method to prolong the drug response time and improve the drug efficacy is still unavailable. TRIM36 was...
Article
Full-text available
Background Circ-ITCH is a circRNA generated from several exons of itchy E3 ubiquitin protein ligase (ITCH) and tumor suppressor served as a sponge for certain miRNAs targeting their parental transcripts of ITCH. However, the role of circ-ITCH in bladder cancer (BCa) was not reported. In the present study, we investigated the role of circ-ITCH in BC...
Article
Based on the theoretical analysis of microbolometer thermoelectric characteristics and temperature response, a new kind of temperature compensation readout integrated circuit for microbolometric focal plane array is proposed. The proposed readout integrated circuit provides different bias voltages for different microbolometers to control their bias...
Article
Full-text available
A novel photonic frequency-doubling up-convertor with compensation of chromatic-dispersion-induced power fading is proposed and experimentally demonstrated based on the cascaded structure of a Mach-Zehnder modulator (MZM) and a dual-parallel Mach-Zehnder modulator (DPMZM). The MZM is driven by a local oscillator (LO) signal biased at the null point...
Article
Introduction: To investigate the feasibility and efficiency of super-selective artery embolization (SAE) before laparoscopic partial nephrectomy (LPN) in treating renal angiomyolipoma (RAML). Materials and methods: A retrospective analysis was conducted on 36 consecutive patients who underwent SAE before LPN (group A, n = 16) or LPN directly (gr...
Article
Based on the fundamental principle of target radiation and microbolometer infrared detection, the microbolometric temperature response to infrared-target temperature change is theoretically analyzed and an exact microbolometric temperature response expression is obtained in theory. The theoretical expression is verified in our laboratory and can be...
Article
Objective: To assess the feasibility of retroperitoneal laparoscopic nephrectomy combined with bench surgery and autotransplantation in treating complex renal tumor. Patients and methods: Six patients with complex renal tumor were seen in our institution between 2010 and 2014. Three patients with bilateral renal cell carcinoma underwent retroper...
Article
Full-text available
Objectives: A model for assuring clamping success was established for laparoscopic partial nephrectomy (LPN) with segmental renal artery clamping (SRAC). Materials and methods: Patients (n = 107; December 2009-September 2011) who underwent LPN with SRAC dependent on the experience of the surgeon and CTA were retrospectively reviewed to determine...
Conference Paper
An RF photonic frontend for multi-channel broadband communication payloads has been proposed to face high frequency satellites challenges demanding higher bandwidth and explosive data bytes. The proposed scheme features broadband, light weight, small size compared with conventional RF frontend in a pure microwave approach. Furthermore, we carry out...
Article
Objective: To evaluate the feasibility and efficiency of laparoscopic partial nephrectomy (LPN) with segmental renal artery clamping, and to analyze the factors affecting postoperative renal function. Patients and methods: A retrospective analysis of 466 consecutive patients undergoing LPN using main renal artery clamping (Group A, n = 152) or s...
Article
Objective: To assess the feasibility and safety of a modified retroperitoneoscopic technique in supine position for the primary tumors located below the level of renal pedicle. Materials and methods: In this retrospective study, 27 patients with primary retroperitoneal tumors located below the level of renal pedicle were recruited from January 2...
Article
A novel kind of high-speed CMOS readout integrated circuit for large-scale microbolometric focal plane array is proposed in this paper. The proposed readout integrated circuit can directly amplify the voltage signals of all microbolometric pixels in focal plane array response to infrared irradiation and then output the amplified voltage signals col...
Article
The first genome-wide association study (GWAS) for bladder cancer has identified a susceptibility locus at 3q28 in the European ancestry. However, the causal variant at 3q28 remains unknown. We conducted a three-stage fine mapping study to identify potential causal variants in the region. A total of 41 single nucleotide polymorphisms (SNPs) across...
Article
Full-text available
Background: Streptococcus thermophilus is a major dairy starter used for manufacturing of dairy products. In the present study, we developed a multilocus sequence typing (MLST) scheme for this important food bacterium. Sequences of 10 housekeeping genes (carB, clpX, dnaA, murC, murE, pepN, pepX, pyrG, recA, and rpoB) were obtained for 239 S. therm...
Article
The unbalanced magnetic pull (UMP) often occurs in different kinds of electrical machines. In induction motors, UMP is usually caused by air-gap eccentricity, which is generally divided into static eccentricity, dynamic eccentricity, mixed eccentricity, and inclined eccentricity, also known as rotor misalignment. However, it has been verified that...
Article
Based on the Preisach model for hysteresis loop, the resistance hysteresis loop characteristic of thermosensitive VO2 thin film is theoretically analyzed. The resistance characteristics dependent on temperature in the resistance hysteresis loop can be obtained through theoretical numerical calculation, and the numerical calculated results are in go...
Article
The microbolometric exact theoretical output responsivity expression for a focal plane array is obtained for the first time. Based on the physical thermal model for a microbolometer, the temperature change behavior of the microbolometer is analyzed and discussed to get its theoretical temperature change expression under pulse voltage bias. With the...
Article
Precise time delay sensing combined with stable frequency dissemination on an arbitrary intermediate point along a fiber-optic loop link is presented. Based on -dispersion-induced radio-frequency (RF) phase locking, the whole loop time delay and phase shift are first stabilized. The time and frequency signals are carried on the same optical carrier...
Article
Full-text available
Objective. Previous studies have investigated the relationships between osteopontin gene polymorphism rs1126616 and OPN levels and urolithiasis, but the results were controversial. Our study aimed to clarify such relationships. Methods. A meta-analysis was performed by searching the databases Pubmed, Embase, and Web of Science for relevant studies....
Article
Full-text available
Structural profiling of healthy human gut microbiota across heterogeneous populations is necessary for benchmarking and characterizing the potential ecosystem services provided by particular gut symbionts for maintaining the health of their hosts. Here we performed a large structural survey of fecal microbiota in 314 healthy young adults, covering...
Article
To study the feasibility and safety of laparoscopic radical cystectomy with intracorporeal orthotopic ileal neobladder and to evaluate the role of endoscopic stapling in neobladder construction. Fifty-five patients with bladder cancer who underwent laparoscopic radical cystectomy were retrospectively examined. Extended pelvic lymph node dissection...
Article
This paper presents a multi-position magnetic field measurement approach to detect air-gap eccentricity in induction machines, including static, dynamic and mixed eccentricity. Using this method, the position of minimum air gap of static eccentricity also can be detected. The sideband components around the fundamental frequency of magnetic flux lea...
Article
Background: Radical nephrectomy with inferior vena cava (IVC) thrombectomy is the preferred treatment for renal cell carcinoma (RCC) with IVC thrombus. However, IVC thrombectomy using a laparoscopic approach has not been reported for high-level thrombi. Objective: To describe the surgical technique for laparoscopic IVC thrombectomy in patients w...
Article
Recent genome-wide association studies have identified 14 genetic variants associated with bladder cancer in Caucasians. The effects of these risk variants and their cumulative effects in Asian populations are unknown. We genotyped these newly identified variants in a case-control study of 1,050 patients diagnosed with bladder cancer and 1,404 cont...
Article
Neosporosis is an intracellular protozoan disease caused by Neospora caninum. Until now, there is no effective vaccine to prevent neosporosis. The host cell binding protein has the potential as neosporosis vaccine. In the present study, a T7 phage display library was constructed and screened using Vero cells to obtain host cell binding protein of N...
Article
Abstract The purpose of this study was to describe a new simplified technique for facilitating vesicourethral anastomosis in laparoscopic radical prostatectomy. After prostate removal, an approximately 15-cm-long absorbable suture with one three-eighths arc needle is passed from the outside in on the full thickness of the bladder neck at the 9 o'cl...
Article
Eccentricity faults more or less exist in all rotating electrical machines. This paper establishes a more precise model of dynamic eccentricity (DE) in electrical machines named as curved dynamic eccentricity. It is a kind of axial unequal eccentricity which has not been investigated in detail so far but occurs in large electrical machines. The ind...