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Publications (37)
To evaluate the feasibility of using intraoperative cell salvage (IOCS) in combination with leucocyte depletion filter (LDF) in eliminating tumour cells from blood salvaged during metastatic spine tumour surgery (MSTS). This is with the view to pave the path for use of IOCS-LDF in MSTS and musculoskeletal oncological surgery.
Sixty consecutive pati...
Presented at the Global Spine Congress (GSC), Buenos Aires, Argentina 20th to 23rd May 2015
Presented at the International Society for the Advancement of Spine Surgery (ISASS) 2015, 15th to 17th April 2015
Background:
Catastrophic bleeding is a significant problem in metastatic spine tumor surgery (MSTS). Allogeneic blood transfusion (ABT) is the mainstay for replenishing blood loss, placing an undue strain on limited blood bank resources and exposing patients to ABT associated risks. Despite using intraoperative cell salvage (IOCS) can reduce ABT r...
Summary:
Metastatic spine tumour surgery (MSTS) is associated with significant blood loss, which is presently replenished by allogeneic blood transfusion (ABT). Using cell saver can reduce ABT requirements but it is contraindicated in tumour surgery due to risk of tumour dissemination. Our study found that cell saver in combination with leucocyte...
Summary: This is the first ever study to report the successful elimination of malignant cells from salvaged blood obtained during metastatic spine tumor surgery using a leucocyte depletion filter. Introduction: Catastrophic bleeding is a significant problem in metastatic spine tumor surgery (MSTS). However, intraoperative cell salvage (IOCS) has tr...
Background:
Catastrophic bleeding is a significant problem in metastatic spine tumor surgery (MSTS). Allogeneic blood transfusion (ABT) is the mainstay for replenishing blood loss, placing an undue strain on limited blood bank resources and exposing patients to ABT associated risks. Despite using intraoperative cell salvage (IOCS) can reduce ABT re...
Introduction:
Intra-operative cell salvage (IOCS) can reduce allogeneic blood transfusion requirements in non-tumour related spinal surgery despite its limited use in metastatic spine tumor surgery (MSTS) due to risk of tumour dissemination.
We hereby present a systematic literature review to answer the following questions:
1. Has IOCS ever been u...
Background: The vertebral column is the commonest site of bony metastasis, accounting for 18,000 new cases in North America yearly. Spinal metastasis often represents an advanced stage in the patient’s primary disease. Such patients are often elderly, have compromised cardiovascular status, poor physiological reserve and altered immune status, all...
Objective
Endometrial cancer mortality disproportionately affects black women and whether greater prevalence of obesity plays a role in this disparity is unknown. We examine the effect of race on post-surgical complications, length of stay, and mortality specifically in a morbidly obese population.
Methods
Black and white women with endometrial ca...
Intraoperative cell salvage (IOCS) has been used in musculoskeletal surgery extensively. However, it has never found its place in musculoskeletal oncologic surgery. We have conducted the first-ever study to evaluate the feasibility of IOCS in combination with a leucocyte-depletion filter (LDF) in metastatic spine tumor surgery. This was to pave the...
Metastatic spine tumour surgery (MSTS) and metastatic musculoskeletal tumour surgery (MMTS) are associated with substantial blood loss. Allogeneic blood transfusion is the present method used to replenish this blood. Intraoperative cell salvage (IOCS) is a viable alternative, but is contraindicated in tumour surgery because of the risk of tumour di...
Summary:
There is emerging evidence of successful application of IOCS and leucocyte depletion filter in removing tumour cells from blood salvaged during various oncological surgeries. Research on the use of IOCS-LDF in MSTS is urgently needed.
Introduction:
Intra-operative cell salvage (IOCS) can reduce allogeneic blood transfusion requirements in...
Background:
Catastrophic bleeding is a significant problem in metastatic spine tumor surgery (MSTS). Allogeneic blood transfusion (ABT) is the mainstay for replenishing blood loss, placing an undue strain on limited blood bank resources and exposing patients to ABT associated risks. Despite using intraoperative cell salvage (IOCS) can reduce ABT r...
Background:
Catastrophic bleeding is a significant problem in metastatic spine tumor surgery (MSTS). Allogeneic blood transfusion (ABT) is the mainstay for replenishing blood loss, placing an undue strain on limited blood bank resources and exposing patients to ABT associated risks. Despite using intraoperative cell salvage (IOCS) can reduce ABT r...
Endometrial cancer is the most common gynecologic malignancy and the fourth most common cause of cancer among women in the United States. Fortunately, the majority of cases, approximately 80%, will be diagnosed at an early stage and prognosis is generally excellent. Two types of endometrial carcinoma are distinguished with respect to biology and cl...
Summary:
There is emerging evidence of successful application of IOCS and leucocyte depletion filter in removing tumour cells from blood salvaged during various oncological surgeries. Research on the use of IOCS-LDF in MSTS is urgently needed.
Introduction:
Intra-operative cell salvage (IOCS) can reduce allogeneic blood transfusion requirements in...
Summary:
This is the first ever study to report the successful elimination of malignant cells from salvaged blood obtained during metastatic spine tumor surgery using a leucocyte depletion filter.
Introduction:
Catastrophic bleeding is a significant problem in metastatic spine tumor surgery (MSTS). However, intraoperative cell salvage (IOCS) has t...
Summary: This is the first ever study to report the successful elimination of malignant cells from salvaged blood obtained during metastatic spine tumor surgery using a leucocyte depletion filter. Introduction: Catastrophic bleeding is a significant problem in metastatic spine tumor surgery (MSTS). However, intraoperative cell salvage (IOCS) has tr...
Background: Intra-operative blood salvage autotransfusion(IBSA) can reduce allogenic blood transfusion requirements in non-tumour related spinal surgery. However, IBSA is deemed contraindicated in metastatic spine tumor surgery(MSTS) due to risk of tumour dissemination. Evidence is emerging from different surgical specialties describing the use of...
Summary: Metastatic spine tumour surgery (MSTS) is associated with significant blood loss, which is presently replenished by allogeneic blood transfusion (ABT). Using cell saver can reduce ABT requirements but it is contraindicated in tumour surgery due to risk of tumour dissemination. Our study found that cell saver in combination with leucocyte d...
Summary:
Metastatic spine tumour surgery (MSTS) is associated with significant blood loss, which is presently replenished by allogeneic blood transfusion (ABT). Using cell saver can reduce ABT requirements but it is contraindicated in tumour surgery due to risk of tumour dissemination. Our study found that cell saver in combination with leucocyte...
Background:
Catastrophic bleeding is a significant problem in metastatic spine tumor surgery(MSTS). However, cell savers(CS) have traditionally been avoided in tumour surgery because of the theoretical concern of promoting tumour dissemination by re-infusing tumour cells into the circulation. Although CS has been extensively investigated in patien...