Przemyslaw Paradowski

Przemyslaw Paradowski
Umeå University | UMU · Institute of Surgical and Perioperative Sciences/Orthopaedics/Sunderby Research Unit

M.D., Ph.D.

About

39
Publications
10,740
Reads
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699
Citations
Additional affiliations
May 2018 - March 2020
Szpital Uniwersytecki Nr 2 im. dr Jana Biziela w Bydgoszczy
Position
  • Head of Department
May 2018 - present
Nicolaus Copernicus University
Position
  • Professor
October 2017 - present
Umeå University
Position
  • lektor
Education
February 2004 - December 2004
Lund University
Field of study
  • post-doc fellowship, orthopedics
August 1986 - May 1992
Military School of Medicine
Field of study
  • medicine

Publications

Publications (39)
Article
Full-text available
Objective: To determine prevalence, incidence and progression of radiographic knee osteoarthritis (OA) in a cohort of subjects with previous meniscectomy. Methods: We assessed 221 subjects (177 men and 44 women) with weight bearing knee radiography twice (assessment A and B) with a follow-up time ranging from 4 to 10 years. All subjects had unde...
Article
Full-text available
Objective: To examine whether the ratio of the second and fourth metacarpal bone length (MC2:MC4) in subjects with prior meniscectomy of the knee is associated with radiographic hand and knee osteoarthritis (OA) and its progression. Design: We assessed 219 subjects (175 men and 44 women) twice with a follow-up time ranging from 4 to 10 years. Pa...
Article
Full-text available
To evaluate the natural history of radiographic hand osteoarthritis (OA) over 10 years. We assessed 118 subjects (30 women) twice (X-ray A and B) with mean (SD) follow-up time of 9.6 (0.4) years. Subjects were of mean (SD) age 52 (10) years at X-ray A and had undergone prior knee meniscectomy. Radiographs of the distal interphalangeal (DIP) and pro...
Article
Full-text available
Self-reported knee complaints may vary with age and gender. Reference data from the adult population would help to better interpret the outcome of interventions due to knee complaints. The objectives of the present study were to describe the variation of self-reported knee pain, function and quality of life with age and gender in the adult populati...
Article
Full-text available
Objective To test the clinimetric properties and to evaluate the internal consistency, validity and reliability of the Polish version of the Knee injury and Osteoarthritis Outcome Score (KOOS) in older patients with end-stage knee osteoarthritis undergoing total knee replacement (TKR). Design and setting A prospective cohort study performed at the...
Article
Full-text available
Femoral reverse oblique intertrochanteric fractures are successfully treated using intramedullary devices. Poor fracture reduction and the use of the inaproppriate implant can lead to implant failure and subsequent malunion or non-union. We present the case of a 21-year-old polytrauma female who, among other injuries, sustained a reverse oblique in...
Article
Full-text available
The associations between individual components of metabolic syndrome (MetS) and bonehealth in children are complex, and data on this topic are sparse and inconsistent. We assessed therelationship between bone turnover markers and markers of the processes underlying MetS (insulinresistance and inflammation) in a group of presumably healthy children...
Article
Full-text available
Citation: Bilinski, W.J.; Szternel, L.; Siodmiak, J.; Paradowski, P.T.; Domagalski, K.; Sypniewska, G. Low Serum 25-hydroxyvitamin D Level Does Not Adversely Affect Bone Turnover in Prepubertal Children. Nutrients 2021, 13, 3324. Abstract: Both vitamin D and insulin-like growth factor 1 (IGF-1) play essential roles in bone metabolism and may inter...
Article
Aim Impaired regulation of glucose metabolism in childhood adversely affects bone health. We assessed the effect of fasting hyperglycemia and insulin resistance on bone turnover markers in prepubertal children with normal glycemia (<100 mg/dL) and fasting hyperglycemia (100-125 mg/dL). Methods Glucose, hemoglobin A1c, IGF-I (insulin-like growth fa...
Article
Full-text available
Objectives Our objective was report short-term results of total hip replacement (THR) and to identify patients with functional recovery and with treatment failure. We also aimed to investigate whether there are any potential predicting factors for functional recovery or treatment failure. Design Prospective cohort study. Clinical examination was p...
Article
Full-text available
Objective The retrospective investigation was carried out to assess whether subjects who fulfilled our proposed recruitment criteria responded more favorably to anterior cruciate ligament reconstruction (ACLR) than those who did not. Methods We retrospectively analyzed 109 skeletally mature subjects (78 men and 31 women) according to the following...
Article
Full-text available
Background The Hip disability and Osteoarthritis Outcome Score (HOOS) is a frequently used patient-reported outcome measure (PROM) for assessment of hip disorders and treatment effects following hip surgery. The objective of the study was to translate and adapt the Hip disability and Osteoarthritis Outcome Score (HOOS) into Polish and to investigat...
Article
The impact of prediabetes and diabetes on skeletal health in the context of increased risk of fragility fractures in adults has been studied recently. However, the prevalence of diabetes, overweight, and obesity have also increased in younger subjects. Current data concerning bone metabolism based on assessment of markers for bone turnover and of b...
Article
Full-text available
Recent studies in mice and humans have shown the tight connection between bone and muscle tissues. Physical activity affects the function of osteocytes, mature bone cells, stimulating the synthesis of several hormone-like myokines in skeletal muscles. Anabolic action of physical exercise on bone is mediated by a myokine called irisin. This protein...
Article
Trauma affects up to 8% of pregnant women and is the leading cause of maternal and fetal morbidity and mortality. Potential complications include maternal injury or death, internal hemorrhage, placental abruption and uterine rupture as well as intrauterine fetal demise, preterm birth, poor condition at birth, and neonatal death. Orthopedic trauma i...
Article
Full-text available
Introduction: Several studies have suggested that anterior cruciate ligament reconstruction (ACLR) without wound drainage has no impact on long-term follow-up. Aim: To investigate a prospective patient series as measured by the patient-administered disease-specific questionnaire Knee injury and Osteoarthritis Outcome Score (KOOS). Material and...
Technical Report
Full-text available
Skala oceny kolana KOOS (Knee Injury and Osteoarthritis Outcome Study) jest jednym z najczęściej stosowanych instru-mentów pomiarowych swoistych dla kolana (condition-targeted, knee-specific scale). Skala pozwala na ocenę stawu kolanowego przez samych chorych (patient-relevant outcomes, PRO). KOOS ocenia zmiany postępujące z tygodnia na tydzień, na...
Article
Full-text available
Introduction Anterior cruciate ligament (ACL) injury is often accompanied by injuries of the menisci. In order to restore knee stability, anterior cruciate ligament reconstruction (ACLR) is performed, with meniscus surgery when needed. The purpose of this study was to assess the medium-term outcome of ACLR in subjects with and without concomitant m...
Article
Background: Suction drain insertion is a common practice in orthopedic surgery, especially after joint arthroplasty to prevent the formation of a hematoma. Theoretically the use of a drain should diminish the volume of hematoma; however the literature has conflicting data. Some authors state that drainage evacuates fluid from a limited area only an...
Article
Full-text available
Knee osteoarthritis (OA) is the most common joint disease. It affects about 12% of adults 60 years of age but its prevalence is expected to rise. The incidence of OA increases with age but the disease can be stable for a long time and could reactivate some years later. Diagnosis of OA is primarily based on history and physical examination and on ra...
Article
Full-text available
Aim: To assess the need and advisability of anterior cruciate ligament reconstruction (ACLR). Methods: We assessed 85 subjects with a mean age of 28 years (SD 10, range 15-57) who had been assigned to ACLR at the Regional Orthopedic Center in Lodz, Poland. All subjects completed a questionnaire covering sport activity, injury mechanism, experience...
Article
Full-text available
Background Knee Injury and Osteoarthritis Outcome Score (KOOS) is available in over 30 languages and a commonly used Patient-Reported Outcome (PRO) for assessment of treatment effects following knee surgery. The aim of the study was to report the linguistic translational process and evaluate the psychometric properties of the Polish version of the...
Article
Full-text available
The aim of the study was to assess the effect of different types of anesthesia on pain intensity in early postoperative period. A total of 87 patients (77 women, 10 men) scheduled for total knee arthroplasty (TKA) were assigned to receive either subarachnoid anesthesia alone or in combination with local soft tissue anesthesia, local soft tissue ane...
Article
Full-text available
The purpose of the study was to assess the influence of barrel-vault high tibial osteotomy on patellar position and to evaluate the reliability and interobserver variability of three patellar height ratios. The radiographs of 24 knees that had undergone barrel-vault height tibial osteotomy with available preoperative as well as postoperative radiog...
Article
Full-text available
Anterior cruciate ligament (ACL) injuries are becoming increasingly prevalent in children and adolescents. In those who had undergone ligament injuries progressive meniscal damage is frequently observed. This, in turn, can lead to osteoarthritis in older age. The aim of the study was to assess the prevalence of ACL injury and/or other intraarticula...
Article
Full-text available
Large variations in pain and function are seen over time in subjects at risk for and with radiographic knee osteoarthritis (OA). We hypothesized that this variation may be related not only to knee OA but also to patient characteristics. The objective of this study was to investigate the influence of age, gender, and body mass index (BMI) on clinica...
Article
Full-text available
In recent years, outcome assessment following different therapeutic procedures has increasingly focused on the patient's perspective. While traditional measures of outcome, including physical examination and imaging diagnostics of the knee are complementary, patient-relevant questionnaires have become more and more important in determining the valu...
Article
Full-text available
Epidemiological studies have, so far, identified factors associated with increased risk for incident or progressive OA, such as age, sex, heredity, obesity, and joint injury. There is, however, a paucity of long-term data that provide information on the nature of disease progression on either group or individual levels. Such information is needed f...
Article
To evaluate the association between radiographic hand osteoarthritis (OA), a disease with marked heredity, and radiographic knee OA in patients treated with meniscectomy. We retrospectively identified 170 patients (mean age 54 years [range 33-87 years], 23% women) who had undergone isolated meniscectomy an average of 20 years earlier (range 17-22 y...
Article
The study was designed to study the effect of pentoxifylline PTX on the chemiluminescence responses of neutrophils and on tumor necrosis factor-alpha (TNF-alpha)-induced priming of neutrophils. The results demonstrate that TNF-alpha stimulated the respiratory burst by neutrophils and primed them for enhanced response to fMLP but not to PMA. The eff...
Article
Pentoxifylline (PTX), methylxanthine derivative and phosphodiesterase inhibitor, has been in use for more than 20 years (with minimal side effects) for the potent hemorrheologic properties and was recently discovered to have influence on function of some immune cells and production of cytokines. Human and animal studies have shown that PTX therapy...

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