Prokopis Annis

The Walton Centre NHS Foundation Trust · Department of Neurosurgery

Retrospective comparative case seriesObjective. Evaluate L5-S1 fusion rates when lower dose BMP-2 (avg. 3.2mg) and pelvic fixation were used, with or without interbody fusion. Pseudarthrosis at L5-S1 is one of the most common complications of long fusions to the sacrum in adult deformity surgery. Strategies for decreasing pseudarthrosis include int...

Background context: Proximal junctional failure (PJF) is a recognized complication of spinal deformity surgery. Acute PJF (APJF) has recently been demonstrated to be 5.6% in the adult spinal deformity (ASD) population. The incidence and rate of return to the operating room for APJF have not been specifically investigated in individuals with sagitt...

Study design: Retrospective case series Objective: To describe the perioperative complications (0-90 days) associated with pedicle subtraction osteotomies (PSO) performed at a tertiary spine center that recently adapted the technique. Methods: We reviewed all 65 patients (47 females and 18 males, mean age of 60 years (range(r) 24-80)) that underwe...

Background White cord syndrome (WCS) refers to the observation of intramedullary hyperintensity due to edema/ischemia and swelling on postoperative T2-weighted MRI sequences in the setting of unexplained neurological deficits after cervical spinal cord decompression. Pathophysiologically, WCS/reperfusion injury (RPI) occurs due to oxygen derived fr...

The most common cause of spinal deformity in adults is iatrogenic flatback and degenerative scoliosis. With an aging population, complex disorders of the spine will become more prevalent and will necessitate correct assessment and management by specialists. Physical examination focusses on gait, posture and compensatory mechanisms. Specific radiolo...

PurposeCoronal malalignment (CM) causes pain, impairment of function and cosmetic problems for adult spinal deformity (ASD) patients in addition to sagittal malalignment. Certain types of CM are at risk of insufficient re-alignment after correction. However, CM has received minimal attention in the literature compared to sagittal malalignment. The...

Spinal injuries occur frequently in the polytrauma patient making the evaluation and management of these potentially catastrophic injuries very important. In the immediate moments following these injuries, steps can be taken to prevent further injury and promote neurological recovery. The use of damage control orthopaedics (DCO) over the past 30 ye...

Background Proximal junctional failure (PFJ) is a common and dreaded complication of adult spinal deformity. Previous research has identified parameters associated with the development of PJF and the search for radiographic and clinical variables continues in an effort to decrease the incidence of PFJ. The lordosis distribution index (LDI) is a par...

Study design: This is a retrospective analysis. Objective: The purpose of this study was to compare the clinical, radiographic, and perioperative complication profiles of performing an interbody and posterior arthrodesis (CAGE) versus posterolateral lumbar fusion (PLF) alone in patients undergoing surgery for degenerative spondylolisthesis (DS)....

Introduction The addition of powdered vancomycin inside the surgical wound site has become a common practice in recent years to decrease the incidence of postoperative orthopedic infections. The effectiveness of vancomycin against bone infections has been well documented and it is commonly delivered locally during a variety of surgeries. While seve...

Introduction Pseudarthrosis at L5–S1 is one of the most common complications of long fusions to the sacrum in adult deformity surgery. Strategies for decreasing pseudarthrosis include interbody fusion, use of BMP-2 at the lumbosacral junction, and the use of sacropelvic fixation, individually or in combination. High-dose BMP-2 (20–40 mg) placed pos...

Study Type Retrospective cohort study. Introduction Acute proximal junctional failure (APJF) was recently defined by the International Spine Study Group as: postoperative fracture of the upper instrumented vertebrae (UIV) or UIV + 1; UIV implant failure; proximal junctional kyphosis (PJK) increase > 15 degrees; or need for proximal extension of the...

Cervical spondylotic myelopathy (CSM) is the clinical manifestation of compression of the spinal cord caused by degenerative changes of the cervical spine. It is a rare but potentially devastating manifestation of cervical spondylosis that usually has a chronic and slowly progressive character. While rare, it is reported as the most common disorder...

Study design: Cross-sectional survey. Objective: The purpose of our study was to evaluate a large population of adolescents from a broad mix of racial/ethnic backgrounds and age groups to better establish baseline normative values for the Scoliosis Research Society-22 (SRS-22). Summary of background data: The SRS-22 instrument was developed to...

BACKGROUND CONTEXT: Recombinant human bone morphogenetic protein-2 (rhBMP-2) is commonly used to augment posterior and interbody spinal fusion techniques and has many reported side effects. Neuroforaminal heterotopic ossification (HO) is a known cause of postoperative leg pain, but the pathohistologic composition of this material is not well unders...

Study design: Retrospective cohort analysis. Objective: To compare early treatment failures, survivorship, and clinical outcomes of 3 procedures used to treat symptomatic lumbar spinal stenosis and degenerative deformity. Summary of background data: Symptomatic lumbar stenosis is commonly seen in association with degenerative deformity, often...

Proximal junctional failure (PJF) is a recognized complication of spinal deformity surgery. Acute proximal junctional failure (APJF) has recently been demonstrated to be 5.6% in the adult spinal deformity population. The incidence and rate of return to the operating room for APJF have not been specifically investigated in individuals with sagittal...

INTRODUCTION As our population ages, we are seeing an increasing number of patients with symptomatic lumbar spinal stenosis associated with lumbar deformity, such as degenerative spondylolisthesis or degenerative scoliosis. The surgical treatment options have traditionally been limited to laminectomy alone or laminectomy and fusion. Interspinous Pr...