Prof. Omar M. Atrooz

• Ph.D in Biochemistry
• Professor at Mutah University

A discrepancy between the production of reactive oxygen species [ROS] and the body’s capacity to cleanse or repair the resulting damage is known as oxidative stress. Antioxidants shield cells against ROS and free radicals, which are extremely reactive because of their unpaired electrons, by preventing other molecules from oxidizing. Antioxidants fr...

Background Respiratory tract infections are a common health issue, driving interest in preventive strategies like nutritional supplements, while evidence on their usage and effectiveness remains limited. In this context, social media platforms, particularly X (formerly Twitter), provide a unique opportunity to gather large-scale public health-relat...

Functional food plays a vital role in promoting human health. Honey is one of these foods that have high nutritional value and medicinal properties. The main aim of this study is to investigate the total content of proteins, phenols and carotenoids in thistle honey extract and to evaluate the biological activities. In addition, to investigate the p...

Application of nanocarrier systems in cancer treatment has emerged as a promising strategy to overcome the limitations of conventional chemotherapy and radiotherapy, which often lead to off-target toxicity and suboptimal therapeutic outcomes. Nanocarriers, including solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), lipid nanoc...

Background: Caralluma europaea (C. europaea) is a genus of shrubs in the Apocynaceae family, endemic to the Mediterranean region. Assessing the anticancer properties, total phenolic and flavonoid content, and antioxidant activity of different C. europaea extracts were the aim of this study.Methods: To determine antioxidant activity, we used three f...

Background: Celiac disease (CD) is an inflammatory small intestine autoimmune disease. The study aims to investigate the association and the detection of ATG5 polymorphism between celiac disease (CD) and H. pylori infection, and the association with Interleukin-33 (IL-33).Methods: The study groups included patients from Iraq, ages 4 to 35. Two prim...

Breast cancer, which affects 36% of all female oncological patients, is the most frequent cancer in the world among women. Since routine laboratory evaluation of serum can be stressful for patients, it is critical to comprehend the features and limitations of salivary test methods in order to achieve an accurate diagnosis of breast cancer. The purp...

Honey is an apiary product with health-promoting properties.However, its biological activities can be affected by its composition of the bioactive molecules. Thus, the study aims to determine the total concentration of proteins, phenolics, and carotenoids in the aqueous extracts of Manuka honey (HM), Sidr honey (HS), Egyptian honey (HE), and mounta...

Contemporary nutraceutical and biomedical sectors are witnessing fast progress in efficient product development due to the advancements in nanoscience and encapsulation technology. Nutraceuticals are generally defined as food substances, or a section thereof, that provide us with health benefits such as disease prevention and therapy. Nutraceutical...

Citation: Khalid, A.; Naeem, M.; Atrooz, O.; Mozafari, M.R.; Anari, F.; Taghavi, E.; Rashid, U.; Aziz, B. State of the Art Synthesis of Ag-ZnO-Based Nanomaterials by Atmospheric Pressure Microplasma Techniques. Surfaces 2024, 7, 680-697. https:// Abstract: Atmospheric pressure microplasma is a simple, cost-effective, efficient, and eco-friendly pro...

Drug and gene carrier vesicles (also referred to as controlled release systems) are advanced dosage forms utilized for disease diagnosis, prevention, and cure. The design rationale is to supply an adequate quantity of the medicaments or diagnostic agents to the pathological sites (target cells) at the right time frame to attain maximum therapeutic...

This literature review offers an extensive exploration of Chaga mushrooms (Inonotus obliquus), focusing on their phytochemical composition, health-promoting attributes, and mechanisms of action. The aim was to provide an up-to-date overview of Chaga's significance in the medicinal sector, emphasizing its potential role in diverse health benefits. T...

Atmospheric pressure Microplasma is a simple, cost-effective, efficient, and eco-friendly procedure, which is superior to the traditional nanomaterials synthesis techniques. It generates high yields and allows for a controlled growth rate and morphology of nanomaterials. The silver (Ag) nanomaterials, with their unique physical and chemical propert...

Background and purpose Hair loss is a prevalent problem affecting millions of people worldwide, necessitating innovative and efficient regrowth approaches. Nanostructured lipid carriers (NLCs) have become a hopeful option for transporting bioactive substances to hair follicles because of their compatibility with the body and capability to improve d...

Micro- and nano-lipidic carriers used for the entrapment, encapsulation, and precise targeting of the bioactive compounds offer significant advantages to the biomedical, pharmaceutical, nutraceutical, and cosmeceutical industries. These lipid and phospholipid-based vesicles can improve the solubility, permeation, pharmacokinetics, pharmacodynamics,...

This comprehensive literature review delves into the multifaceted attributes of Trametes versicolor, commonly known as turkey tail mushroom. The turkey tail mushroom stands as a noteworthy source of diverse bioactive compounds with potent health benefits. This review offers a contemporary synthesis of its phytochemical constituents and their multif...

This literature review provides an up-to-date exploration of the multifaceted attributes of maitake mushrooms (Grifola frondosa), elucidating their bioactive phytochemicals and diverse health advantages, including their substantial role in supporting human health and potential incorporation into the medicinal industry. Carbohydrates and protein are...

: Lipidic carriers employed for the entrapment, encapsulation and precise targeting the bioactive compounds offer significant advantages to the biomedical, pharmaceutical, nutraceutical and cosmeceutical industries. These lipid and phospholipid‐based vesicles can improve the solubility, permeation, pharmacokinetics, pharmacodynamics and bioavailabi...

Artemisia herba-alba L. (A. herba-alba), growing in the Mediterranean regions, contains various phytochemical compounds with exceptional pharmacological and chemical properties. The present study aims to characterize chemical and biological activities of A. herba-alba’s methanolic extract according to total protein, total phenols, antioxidant, an...

Mirabilis jalapa L. has been used traditionally in herbal medicine for various purposes, including as a laxative, diuretic, and treatment of inflammations and fever, as it contains various phytochemical compounds. The present study aims to analyze the phytochemical and lipidic profiles of M. jalapa and characterize its methanol seed extract. It als...

This study was carried out to evaluate the effects of the heavy metal (HM) compounds CuSO4, HgCl2, and ZnSO4 on wheatgrass, Triticum aestivum. Juice was extracted from treated leaves after 14 days of treatment for analysis of biochemical parameters including antioxidant activity, levels of protein and chlorophyll, and peroxidase (POX) enzyme activi...

Artemisia herba-alba L. (A. herba-alba), growing in the Mediterranean regions, contains various phytochemical compounds with exceptional pharmacological and chemical properties. The present study aims to characterize chemical and biological activities of A. herba-alba’s methanolic extract according to total protein, total phenols, antioxidant, anti...

Background: Glycolipid metabolism disorders (dysglycolipidemia) are characterized by elevated levels of glycolipid profile components and fasting blood glucose. Dysglycolipidemia are major threats to human health and life. Therefore, the aim of this cross-sectional study is to estimate the prevalence of dysglycolipidemia and the existence of associ...

A new Schiff base, 4-((1E,2E)-3-(furan-2-yl)allylidene)amino)-N-(5-methylisoxazol-3-yl) benzene-sulfonamide (L), was synthesized by thermal condensation of 3-(2-furyl)acrolein and sulfamethoxazole (SMX), and the furan Schiff base (L) was converted to a phenol Schiff base (L’) according to the Diels–Alder [4 + 2] cycloaddition reaction and studied e...

The final products formed from the various systems of the Maillard reactions possess different functional properties such as browning intensity, antioxidant activity, and emulsion stability. To study these properties and activities, different systems of whey proteins reaction with glucose and fructose at different concentrations to form a new model...

The Ganoderma genus is known for its diverse use as a functional food and therapeutic agent. This fungus has over 428 species, with Ganoderma lucidum being the most studied. The Ganoderma species produce several secondary metabolites and bioactive compounds like polysaccharides, phenols, and triterpenes, which are largely responsible for their ther...

Protease inhibitors have considerable applications in biomedicine, biotechnology, and therapy. The aim of the study was to evaluate the methanol crude extracts of aerial portions of Portulaca oleracea (P. oleracea) for anti-inflammatory, antioxidant, and protease inhibitor activities, and to evaluate their inhibitory action against various thera...

Background The development of digital technologies and the evolution of open innovation approaches have enabled the creation of diverse virtual organizations and enterprises coordinating their activities primarily online. The open innovation platform titled “International Natural Product Sciences Taskforce” (INPST) was established in 2018, to bring...

Background: The development of digital technologies and the evolution of open innovation approaches have enabled the creation of diverse virtual organizations and enterprises coordinating their activities primarily online. The open innovation platform titled "International Natural Product Sciences Taskforce" (INPST) was established in 2018, to brin...

The aqueous crude extract of purslane (Portulaca oleracea L.) was characterized for its antioxidant activity, total amounts of proteins, and phenol content. Furthermore, the kinetic parameters (Vmax and Km) of the enzyme polyphenol oxidase (PPO) in the crude extract of purslane were analyzed in the presence of the heavy metals (HM) Cu and Zn. Re...

is work investigates the effect of the alcoholic extract of Anabasis syriaca Iljin on biochemical and histological parameters in male rats. e lethal dose (50% of the plant extract) was assessed, and three separate doses (1/10 th , 1/15 th , and 1/20 th) were orally gavaged for two weeks into three study groups of animals (five rats in each group),...

The activity and kinetic parameters of the enzyme polyphenol oxidase (PPO) in crude extracts of the fruits of Paradise apple (Pyrus malus L.), cucumber (Cucumis sativus L.), squash (Cucurbita pepo L.), pomegranate rind and seeds (Punica granatum L.), and the leaf of cactus (Opuntia ficus-indica (L.) were investigated. The highest browning intensity...

The present study provides plant-derived extracts to characterize the activity and kinetics of protease enzymes of Mentha piperita L and Thymus capitatus L. The results illustrated that these crude extracts have a proteolytic activity within optimum pH (3–9) and optimum temperature (35–50°C). The study of the ionizable groups in or around the activ...

In this study, we evaluated the biological activity of crude plant extracts of Asphodeline lutea and Peganum harmala. The in vitro antiproliferative activity, the effects on cell cycle phases, and the antioxidant and antibacterial activities of the crude extracts were investigated. The extracts revealed antiproliferative activity against three huma...

In this study, we evaluated the biological activity of crude plant extracts of Asphodeline lutea and Peganum harmala. The in vitro antiproliferative activity, the effects on cell cycle phases, and the antioxidant and antibacterial activities of the crude extracts were investigated. The extracts revealed antiproliferative activity against three huma...

Hormonal and biochemical disturbances play an important role in development of infertility cases. Therefore, this study was conducted to evaluate the prolactin level and to explore the association between prolactin and thyroid stimulating hormone (TSH) and other hormones in the diagnosed infertile women in Ma'an governorate. The study was performed...

The aim of this study was to determine the activity of β-galactosidase in the crude extracts of Pleurotus ostreatus in the presence and absence of various heavy metals. β-galactosidase (EC 3.2.1.23), is a hydrolase enzyme which helps in the hydrolysis of lactose into monosaccharides. Characterization of β-galactosidase from Pleurotus ostreatus was...

p>β-galactosidase (EC 3.2.1.23) was extracted from Cuminum cyminum and Curcuma longa . The crude extracts of these plants were then characterized in term of pH, temperature, and enzyme kinetic. The crude extracts were also used in hydrolysis of lactose in milk and whey. The enzyme activity was measured by its ability to hydrolyze the substrate o-ni...

β-galactosidase (EC 3.2.1.23) is important in the formation of a medicinal plant Artemisia judaica (al-ba’atharan) aroma. The crude plant extracts of Artemisia judaica were used to characterize the enzyme in the term of pH, temperature, enzyme kinetic and effects of some heavy metals on its activity. The enzyme activity was measured by its ability...

The catalytic activities and the kinetic parameters of crude enzymes polyphenol oxidase (POX) and peroxidase (PPO) ezymes of crude extracts of Rosmarinus officinalis, Petroselium cripsum, and Eruca Sativa were invistigated in the presence and absence of various heavy metals. The results showed that the crude enzyme (PPO) activity in the selected pl...

The proteolytic activity in crude extracts of pumpkin and pomegranate fruits was measured with albumin, egg albumin and casein as substrates. The kinetic parameters (Vmax) and (Km) were investigated using the different substrates and revealed a broad specificity from both samples. Both crude extracts appeared to be active over a wide pH range with...

The proPO system is an important humoral immune response among invertebrates. It has been found in many species, including the bivalves, C. gigas, Mytilusedulis,Pernaviridis andPernaperna(Coles and Pipe 1994; Asokan et al. 1997;Hellio et al. 2007). ProPO is present in the plasma or haemocyte compartments of hemolymph, or in both depending on the sp...

A Thesis Submitted to the Deanship of Graduate Studies in Partial Fulfillments of the Requirements for the Degree of Master of Biology - Department of Biology Mu'tah University, 2013

A Thesis Submitted to the Deanship of The Graduate Studies in Partial Fulfillment of the Requirements for the Degree of Master of Science-Department of Biology Mu'tah University, 2013

Master thesis By Areen Talal Amarin Supervisor Dr. Omar M. Atrooz

Master Thesis- Mohammad Abu Khalil; Supervisor: Prof. Omar Atrooz

Master Thesis about: Association Between Thyroid Hormones and Obesity in Children in Al-Karak Region

Cumin (Cuminum cyminum L.) and caraway (Carum carvi L.) are aromatic plants within the Apiaceae family. They have a variety of purposes and demonstrate antioxidant and antimicrobial properties. Methanolic and acetonic seed extracts of both plants were able to neutralize free radicals and carried antioxidant properties. Both seed extracts were able...

Liposomes are often used as a carrier to improve the therapeutic activity and safety of drugs. The lipid composition of liposomes plays an important role in determining the behavior of liposomes in phases. In this study, the phospholipid and alkylresorcinol content in crude acetone extracts of seeds of Canna indica L., Cucumis melo L. and Prunus ar...

The effects of alkyIresorcinols (ARs) obtained from the acetonic extract of whole-wheat grains (Triticum sativum) on the stability, encapsulation efficiency and permeability of liposomes was investigated in this study. This extract could form vesicles alone (AR liposomes) as well as incorporation of the extracted ARs with phosphatidylcholine (PC) (...

Different plant seeds extracts of Citrus sinensis, Hordeum sativum, Triticum sativum, Canna indica, Citrullus vulgaris and Capsicum annuum were evaluated for their antioxidant activity by the following methods: 2,2-diphenyl-1-pycril-hydrazyl (DPPH) radical scavenging, reducing power, RBCs hemolysis and linoleic acid oxidation, a long with the deter...

Results of this study intended to determine the different properties of various honey samples collected from different regions in Jordan. These results proved that there were differences in some properties of honey samples and were found to meet the major national and international honey specifications. The thermal behavior of honey samples showed...

The effects of Maillard reaction products (MRPs) on apple and potato polyphenol oxidase (PPO) were estimated spectrophotometrically. Model systems of glucose and amino acids [lysine (lys), tyrosine (tyr), proline (pro), cysteine (cys), glumatic acid (glu), aspartic acid (asp), and histidine (his)] were heated at 90 °C for 3 h. The MRPs showed inhib...

The antioxidant activity and the polyphenols and flavonoids contents of methanolic extracts of plant seeds of Canna indica, Hordium sativum and Capsicum annuum were investigated. These extracts were found to exhibit strong scavenging effects on 1, 1-Diphenyl-2-picryle-hydrazyl (DPPH) radicals and have significant amounts of flavonoids and polypheno...

The effect of the alcoholic extract of Arbutus andrachne on certain biochemical parameters and the histology of the visceral organs in nonpregnant adult female rats was studied. The lethal dose 50% (LD)50 was estimated, and three different doses (1/10th , 1/15th and 1/20th ) of the LD50 extracts were injected intra-peritoneally for 14 consecutive d...

Liposomes made from phosphatidylcholine (PC) or PC-fatty acid ester mixtures have been shown to induce an activation of the respiratory burst in human blood monocytes and alveolar macrophages (AM). Incorporation of 1,2-diacylglycerol or arachidonic acid into PC liposomes significantly enhanced the effect. In the case of AM, the effect of PC liposom...

It is shown that in comparison with phorbol myristate and the calcium ionophore A23187, phosphatidylcholine liposomes less effectively induce the formation of superoxide radical in human peripheral blood monocytes. The efficiency of liposomes moderately increase after incorporation of 1,2-diacylglycerol and gangliosides, but not of esterified fatty...

Formation of primary metabolites of oxidative burst in alveolar macrophages from healthy subjects and patients with chronic lung diseases is studied using the method of luminoldependent chemiluminescence. Incubation with liposomes composed from phosphatidylcholine and a phosphatidylcholine-fatty acid esters mixture induces similar activation of oxi...