Prince Bawuah

Prince Bawuah
University of Cambridge | Cam · Department of Chemical Engineering and Biotechnology

25.25
 · 
Docent- Terahertz Physics
About
30
Research items
4,002
Reads
160
Citations
Research Experience
Jun 2018
University of Cambridge
Position
  • Research Associate
Aug 2017 - Jun 2018
University of Eastern Finland
Position
  • Postdoctoral Researcher
Mar 2017 - Sep 2017
University of Eastern Finland
Position
  • Postdoctoral Researcher
Network
Cited By
Followers
Following
Projects
Projects (2)
Project
The goal is to achieve a fast, non-invasive and non-destructive approach to ascertain the ingress of liquid in a tablet.
Research
Research items (30)
Conference Paper
Full-text available
Surface plasmon polaritons (SPPs) are electromagnetic surface waves which can propagate at the interface of a metal and a dielectric. The SPPs are photon-electron hybrid modes which are tightly confined to the subwavelength surfaces [1]. These surface waves can mediate the optical transmission through a nanoslit that is surrounded by an array of re...
Article
Localized surface plasmons are highly confined modes at the subwavelength surfaces. The modes provide enhanced electric field intensity sites in close proximity to the surface which display potential applications in the form of optical-sensing devices. Intriguingly, at nanoscale, the modes can also increase the optical transmission through the aper...
Article
Full-text available
Surface plasmon polaritons are electromagnetic surface waves, which, due to their nanoscale nature, are efficiently used for modifying an output of optical field through a metallic nanoslit, e.g., extraordinary optical transmission and beaming of light. Herein, the phenomenon of optical beaming by employing a regular array of semicylinder-shaped gr...
Article
Full-text available
Metamaterial absorbers deliver potential applications in the field of civil and military products. Herein, we proposed a dual-band metamaterial absorber in a range of terahertz (THz) frequency based on numerical simulations. A novel design of swastika-shaped microslots in aluminum film is introduced that displays two high absorbance peaks at the re...
Article
Metamaterial absorbers, due to their potential applications in the field of photonics, are vastly studied in the last decade. Herein, we present a novel design of a resonant metamaterial absorber in the terahertz (THz) region based on numerical simulations. This perfect THz absorber, due to its symmetry, is highly independent on the polarization st...
Article
Heckel analysis is a widely used method for the characterisation of the compression behaviour of pharmaceutical samples during the preparation of solid dosage formulations. The present study introduces an optical version of the Heckel equation that is based on combination of the conventional Heckel equation together with the linear relationship def...
Article
Terahertz (THz) spectra from the pure forms [i.e. the active pharmaceutical ingredients (APIs)] of four commonly used antimalarial drugs are reported. The well-defined spectral fingerprints obtained for these APIs in the spectral range of 0.1 THz–3 THz show the sensitivity of the THz time-domain spectroscopic (THz-TDS) method for screening antimala...
Article
Full-text available
Background: Liquid fuel adulteration has several far-reaching impacts such as environmental pollution. A widespread practice is typically the adulteration of diesel oil by kerosene. The relatively cheap price of kerosene is probably the most important reason for its usage in illegal adulteration. Herein, we demonstrate the use of a prototype optica...
Article
Traditionally, the development of a new solid dosage form is formulation-driven and less focus is put on the design of a specific microstructure for the drug delivery system. However, the compaction process particularly impacts the microstructure, or more precisely, the pore architecture in a pharmaceutical tablet. Besides the formulation, the pore...
Article
Cost effectiveness, ease of use and patient compliance make pharmaceutical tablets the most popular and widespread form to administer a drug to a patient. Tablets typically consist of an active pharmaceutical ingredient and a selection from various excipients. A novel highly porous excipient, functionalised calcium carbonate (FCC), was designed to...
Article
Pharmaceutical tablets are typically manufactured by the uni-axial compaction of powder that is confined radially by a rigid die. The directional nature of the compaction process yields not only anisotropic mechanical properties (e.g. tensile strength) but also directional properties of the pore structure in the porous compact. This study derives a...
Article
Background: The surface quality of pharmaceutical tablets plays an important role, especially in the drug release of a tablet and hence affects the bioavailability of the drug. Furthermore, important tablet's properties such as coating uniformity and mechanical integrity that can be predicted based on the known surface properties manifest the inevi...
Article
The objective of this study is to propose a novel optical compressibility parameter for porous pharmaceutical tablets. This parameter is defined with the aid of the effective refractive index of a tablet that is obtained from non-destructive and contactless terahertz (THz) time-delay transmission measurement. The optical compressibility parameter o...
Article
The physical properties and mechanical integrity of pharmaceutical tablets are of major importance when loading with active pharmaceutical ingredient(s) (API) in order to ensure ease of processing, control of dosage and stability during transportation and handling prior to patient consumption. The interaction between API and excipient, acting as fu...
Article
Full-text available
Novel excipients are entering the market to enhance the bioavailability of drug particles by having a high porosity and thus providing a rapid liquid uptake and disintegration to accelerate subsequent drug dissolution. One example of such a novel excipient is functionalised calcium carbonate (FCC), which enables the manufacture of compacts with a b...
Thesis
Full-text available
This thesis proposes a suit of non-destructive methods based on terahertz time-domain techniques, which allow the prediction of important quality parameters of pharmaceutical tablets. Additionally, a novel structural (S) parameter, which can offer valuable information on the structural arrangement of the various constituents in a porous matrix, has...
Article
In this study, terahertz time-domain spectroscopic (THz-TDS) technique has been used to ascertain the change in the optical properties, as a function of changing porosity and mass fraction of active pharmaceutical ingredient (API), of training sets of pharmaceutical tablets. Four training sets of pharmaceutical tablets were compressed with microcry...
Article
Full-text available
In this paper, we have studied terahertz (THz) pulse time delay of porous pharmaceutical microcrystalline compacts and also pharmaceutical tablets that contain indomethacin (painkiller) as an active pharmaceutical ingredient (API) and microcrystalline cellulose as the matrix of the tablet. The porosity of a pharmaceutical tablet is important becaus...
Article
Full-text available
This work highlights the use of Hashin– Shtrikman (H–S) bounds in the prediction and verification of the effective refractive index, the height and the Young’s modulus of given training sets of pharmaceutical compacts using the measured time delay of a THz pulse traversing the compacts. Set A consisted of 13 microcrys- talline cellulose (MCC) compa...
Article
Full-text available
In order to find counterfeit drugs quickly and reliably, we have developed ‘tape method’ a transmission spectroscopic terahertz (THz) measurement technique and compared it with a standard attenuated total reflection (ATR) THz spectroscopic measurement. We used well-known training samples, which include commercial paracetamol and aspirin tablets to...
Article
Full-text available
In this paper, far-infrared (FIR) spectroscopic techniques have been employed to detect different calcium carbonate crystal concentrations in powder mixtures. We have compared absorption spectral features of both pure and mixtures of natural ground calcium carbonate (GCC) and synthetic precipitated calcium carbonate (PCC). It is evident that the ab...