Primoz Gradisek

Primoz Gradisek
Ljubljana University Medical Centre | UMC · Department of Anaesthetics and Surgical Intensive Care

MD PhD

About

28
Publications
17,913
Reads
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1,142
Citations
Introduction
Primoz Gradisek currently works at the Department of Anaesthetics and Surgical Intensive Care, Ljubljana University Medical Centre. Primoz does research in Neuroradiology, Neurology and Neurosurgery. Their current project is 'Traumatic Brin Inury.'
Additional affiliations
July 2016 - present
Medical Faculty, University of Ljubljana
Position
  • Professor (Assistant)
August 1998 - present
Ljubljana University Medical Centre
Position
  • ICU physitian

Publications

Publications (28)
Article
Background The indications for intracranial pressure (ICP) monitoring in patients with acute brain injury and the effects of ICP on patients’ outcomes are uncertain. The aims of this study were to describe current ICP monitoring practises for patients with acute brain injury at centres around the world and to assess variations in indications for IC...
Article
Background: Currently established prognostic models in traumatic brain injury (TBI) include non-contrast CT which is insensitive to early perfusion alterations associated with secondary brain injury. Perfusion CT (PCT) on the other hand offers insight into early perfusion abnormalities. We hypothesized that adding CT perfusion and permeability dat...
Article
Full-text available
Background Severe bleeding after blunt maxillofacial trauma is a rare but life-threatening event. Non-responders to conventional treatment options with surgically inaccessible bleeding points can be treated by transarterial embolization (TAE) of the external carotid artery (ECA) or its branches. Case series on such embolizations are small; consider...
Article
Background: Real-life experience with idarucizumab, which reverses the anticoagulant effect of dabigatran, is currently limited. Objective: To evaluate efficacy and safety of the clinical use of idarucizumab after its availability in Slovenia. Methods: We analysed consecutive cases treated with idarucizumab in Slovenia from January to October...
Article
A concerted e ort to tackle the global health problem posed by traumatic brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insu ciently recognised, proportions. Worldwide, more than 50 million people have a TBI each year, and it is estimated that about half the world’s population will have one or more TBIs over their...
Article
Full-text available
Introduction. Cardiopulmonary resuscitation is influenced by the quality of basic life support (BLS). The primary objective of our study was to compare efficiency in the acquisition of BLS skills using conventional training and the 4-stage approach as a teaching method for BLS training. Methods. In a prospective, randomised, 2-parallel group study,...
Conference Paper
Full-text available
Introduction Treatment with sevoflurane was associated with uncontrollable increases in intracranial pressure (ICP) in 32% of patients with subarachnoid hemorrhage or stroke [1]. The aim of this study was to evaluate changes in ICP in our case series of neurocritical patients. Methods A retrospective analysis performed between November 2015 and Nov...
Article
Aim: To investigate benefits of prophylactic antibiotics in comatose survivors of out-of-hospital cardiac arrest (OHCA). Methods: Patients without evidence of tracheobronchial aspiration on admission bronchoscopy were randomized to prophylactic Amoxicillin-Clavulanic acid 1.2g every 8h (P) or clinically-driven antibiotics (C) administered if sig...
Article
Full-text available
Primary objective: To assess the unusual use of a volatile anaesthetic for treatment of life-threatening bronchospasm in a patient with traumatic brain injury (TBI). Research design: Case report. Methods and procedures: This study presents a previously healthy 30-year-old man with severe TBI and bronchospasm-induced acute hypercapnia. He was t...
Article
Full-text available
Introduction.The maintainaning of optimal perioperative fluid and electrolyte balance in the perioparative period (before, during and after an operation) is a crucial for anaesthesia and intensive therapy. Fluid treatment interferes with the metabolism and functioning of all organ systems, therefore it is important that the patient gets the right t...
Article
Full-text available
Introduction: The maintainaning of optimal perioperative fluid and electrolyte balance in the perioparative period (before, during and after surgery) is crucial for anaesthesia and intensive therapy. Fluid treatment interferes with the metabolism and functioning of all organ systems, therefore it is important that the patient gets the right type an...
Article
Full-text available
Background: Acute respiratory distress after transfusion is an underreported, but potentially serious complication. Concomitant pre-existing lung injury and frequent transfusions in critically ill and injured patients make identification of transfusion-related pulmonary reactions difficult. Special attention by critical care specialists, haematolog...
Article
Full-text available
Background: In the last few years new approaches to the diagnosis and management of abdominal trauma were introduced, and in addition, monitoring of individual organ function in the intensive care units has become an almost daily practice. In our article we review the principles of assessment and management of injured individual abdominal organs fr...
Article
Full-text available
Objective: To examine the prognostic ability of protein S100B, neuron-specific enolase (NSE) and glial fibrillary acid protein (GFAP) for prediction of 1-year mortality in patients with traumatic brain injury (TBI) in relation to clinical and radiological characteristics of TBI. Methods: Brain injury was quantified in 84 patients (Glasgow Coma S...
Article
Full-text available
Acute respiratory failure is common in trauma patients and can be a threat to life in severe thoracic injury. We represent a case of severe respiratory failure after blunt thoracic injury with uncontrollable bleeding and massive air leak which was successfully managed with high frequency oscillatory ventilation. In our opinion high frequency oscill...
Article
Full-text available
Izvleček Izhodišča: Diagnostična in napovedna moč kli-ničnih in radioloških kazalnikov predvsem blage oblike nezgodne možganske okvare je majhna. Metode in rezultati: Za sistematični pregled raziskav o biokemijskih označevalcih in nezgo-dni možganski okvari, objavljenih v zadnjem desetletju, smo uporabili elektronsko bazo ame-riške nacionalne knjiž...
Article
Full-text available
Background: Currently used clinical and radiological findings of particularly mild traumatic brain injury have limited diagnostic and prognostic value. Methods and results: We conducted a systematic review of selected primary clinical studies on biochemical markers of traumatic brain injury in the last 10 years, using an electronic search of the Na...
Article
Full-text available
To investigate whether preemptive administered lornoxicam changes perioperative platelet function during thoracic surgery. A total of 20 patients scheduled for elective thoracic surgery were randomly assigned to receive either lornoxicam (16 mg, i.v.; n = 10) or placebo (n = 10) preoperatively. All patients underwent treatment of solitary lung meta...
Article
Full-text available
It is assumed that endothelial dysfunction due to arterial hypertension could be improved or even normalized by antihypertensive treatment. The present study was designed to explore that assumption in patients with essential hypertension treated with an angiotensin-converting enzyme (ACE) inhibitor-enalapril. Twenty-eight patients (mean age: 55.1 y...
Article
Quantitative determination of HBV DNA in serum samples is indispensable for predicting disease progression and for monitoring the antiviral treatment in patients with chronic HBV infection. Three commercial assays for quantification of HBV DNA: Digene Hybrid-Capture HBV DNA Assay, Bayer Quantiplex HBV DNA Assay and Roche Amplicor HBV Monitor Test w...

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