Praveen Kumar Singh

Praveen Kumar Singh
University of Allahabad · Department of Botany

Doctor of Philosophy

About

40
Publications
3,526
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170
Citations
Introduction

Publications

Publications (40)
Chapter
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The Sangam area of Prayagraj, where the Ganga, Yamuna and mythical Saraswati rivers meet, is a significant religious and cultural site attracting millions of pilgrims annually. This study examines the ecological impacts of pilgrimage activities on the Sangam ecosystem, focusing on water quality, biodiversity and waste management. Primary data were...
Article
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This study investigates the taxonomic diversity and conservation status of endemic plant species in the Gangetic plains of Prayagraj. Field surveys and literature review identified 125 endemic plant species, distributed across 45 families and 78 genera. Assessment of their conservation status revealed that 30% of these species are threatened, with...
Article
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Understanding the intricate interactions between plants, mycorrhizal fungi, and soil health is crucial for sustainable agriculture and climate change mitigation. This review synthesizes current research to elucidate the multifaceted role of plant-mycorrhizal-fungal interactions in soil health and carbon sequestration in agroecosystems. A meta-analy...
Article
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Distal Sensory Peripheral Neuropathy (DSP) is a common complication in HIV-infected individuals, leading to chronic pain and reduced quality of life. Even with antiretroviral therapy (ART), DSP persists, often prompting the use of opioid analgesics, which can paradoxically worsen symptoms through opioid-induced microbial dysbiosis. This study emplo...
Article
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There has been a rapid increase in neonates born with a history of prenatal opioid exposure. How prenatal opioid exposure affects pain sensitivity in offspring is of interest, as this may perpetuate the opioid epidemic. While few studies have reported hypersensitivity to thermal pain, potential mechanisms have not been described. This study posits...
Preprint
Full-text available
Distal Sensory Peripheral Neuropathy (DSP) is a common complication in HIV-infected individ-uals, leading to chronic pain and reduced quality of life. Despite antiretroviral therapy (ART), DSP persists, often prompting the use of opioid analgesics, which can paradoxically worsen symptoms through opioid-induced microbial dysbiosis. This study employ...
Article
TET methylcytosine dioxygenase 2 ( TET2) loss-of-function mutations induce a pre-malignant state known as clonal hematopoiesis of indeterminate potential (CHIP). CHIP occurs in approximately 10% of people over 65 years of age and confers a 10-fold greater risk of developing hematological malignancy. Several environmental factors, including radiatio...
Article
Full-text available
The current study of the aquatic and marshland plants growing in thedistrict Semara Taal, Siddharth Nagar. A total no. of 94 species under 71 genera over 40 families such as Acanthaceae, Alismataceae, Amaranthaceae, Apiaceae, Aponogetonaceae, Araceae, Asteraceae, Brassicaceae, Boraginaceae, Ceratophyllaceae, Commelinaceae, Convolvulaceae, Cyperacea...
Article
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Purpose The goal of this systematic review was to examine the current literature on the urinary microbiome and its associations with noninfectious, nonmalignant, urologic diseases. Secondarily, we aimed to describe the most common bioinformatics used to analyze the urinary microbiome. Methods A comprehensive literature search of Ovid MEDLINE using...
Article
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Author have reported 221 species out of 169 genera during the floristic survey of angiosperm of Suraha Tal Bird Sanctuary district of Ballia, Uttar Pradesh, As habit wise including 181 herbs, 06 shrubs, 31 trees & 03 climbers while habitat wise dwelling 176 & 45 genera terrestrial and wetland respectively. Out of 221 species belongs 48 family viz.
Article
Full-text available
Author have reported 221 species out of 169 genera during the floristic survey of angiosperm of Suraha Tal Bird Sanctuary district of Ballia, Uttar Pradesh, As habit wise including 181 herbs, 06 shrubs, 31 trees & 03 climbers while habitat wise dwelling 176 & 45 genera terrestrial and wetland respectively. Out of 221 species belongs 48 family viz.
Article
Full-text available
Opioid crisis is an ongoing epidemic since the past several decades in the United States. Opioid use-associated microbial dysbiosis is emerging as a key regulator of intestinal homeostasis and behavioral responses to opioid. However, the mechanistic insight into the role of microbial community in modulating host response is unavailable. To uncover...
Article
Full-text available
The ongoing opioid epidemic has left millions of people suffering from opioid use disorder due to the over-prescription of highly addictive substances. Chronic opioid exposure leads to dependence, where the absence of the drug results in negative symptoms of withdrawal, often driving patients to continue drug use; however, few therapeutic strategie...
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Full-text available
Article
Objectives: To study the semen microbiome profile in men with non-obstructive azoospermia (NOA) would differ from that of fertile controls (FC). Design: Using quantitative PCR and 16s rRNA, we sequenced semen samples from men with NOA (FSH > 10 IU/mL, testis volume < 10cc) and fertile controls and performed comprehensive taxonomic microbiome ana...
Article
TET2 loss-of-function mutations induce a pre-malignant state known as clonal hematopoiesis of indeterminate potential (CHIP). CHIP occurs in approximately 10% of people over 65 years of age and confers a 10-fold greater risk of developing hematological malignancy. Several environmental factors, including radiation, sleep deprivation, atherosclerosi...
Article
Full-text available
Background and Purpose Opioids are the standard drug for pain management; however, their effects on gastric dysfunction are relatively understudied. Opioid users have a higher incidence of gastric pathology leading to increased hospitalization. Herein, we investigated the consequences of morphine use on gastric pathology and the underlying mechanis...
Article
Full-text available
Despite the many advancements in the field of pain management, the use of intravenous opioids, such as morphine, in neonates is still a challenge for clinicians and researchers, as the available evidence concerning the long-term consequences of such an early exposure is limited. In particular, little is known concerning the long-term consequences o...
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Full-text available
The pathophysiological mechanism(s) driving non-alcoholic fatty liver disease, the most prevalent chronic liver disease globally, have yet to be fully elucidated. Here, we identify regulator of G protein signaling 6 (RGS6), up-regulated in the livers of NAFLD patients, as a critical mediator of hepatic steatosis, fibrosis, inflammation, and cell de...
Chapter
In recent years, there has been a rapid surge in the number of resistant strains of bacterial pathogens, mainly due to misuse of antibiotics in our day-to-day environment for treating common ailments. Hence new drug discovery is a priority. The discoveries of new antimicrobials increasingly rely on genotypic data resulting from whole genome sequenc...
Article
Full-text available
Excessive ingestion of the common analgesic acetaminophen (APAP) leads to severe hepatotoxicity. Here we identify G protein β5 (Gβ 5 ), elevated in livers from APAP overdose patients, as a critical regulator of cell death pathways and autophagic signaling in APAP-exposed liver. Liver-specific knockdown of Gβ 5 in mice protected the liver from APAP-...
Article
Full-text available
Objectives The spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus has been unprecedentedly fast, spreading to more than 180 countries within 3 months with variable severity. One of the major reasons attributed to this variation is genetic mutation. Therefore, we aimed to predict the mutations in the spike protein (S) of th...
Article
Full-text available
Genotype MTBDRsl Version 1 (V1.0) was recommended as an initial test for rapid detection of pre-extensively drug resistant (pre-XDR) and extensively drug resistant tuberculosis (XDR-TB). However, in recent years a number of novel mutations are identified that confer resistance. Thus, Genotype MTBDRsl V2.0 was endorsed by WHO. Though, Genotype MTBDR...

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