Praveen Sharma

IPS Academy · College of Pharmacy

Chemical, Material Sciences & Nano technology book series aims to bring together leading academic scientists, researchers and research scholars to exchange and share their experiences and research results on all aspects of Chemical, Material Sciences & Nano technology. The field of advanced and applied Chemical, Material Sciences & Nano technology...

Acorus calamus Linn is a species of perennial, semi aquatic, aromatic herb with creeping rhizomes; it belongs to the family Acoraceae. In Ayurveda Acorus calamus Linn is also known as VACHA and publically known as Bacha or sweet flag. It is a highly valued herb as it acts as a rejuvenator for brain and nervous system. It is a main medhya drug, whic...

To evaluate the in-vitro free radical scavenging activity of leaves Mentha pulegium linn. Petroleum ether, ethanol, aqueous extracts of Mentha pulegium were prepared, with successive extraction in soxhlet apparatus. Each extract was selected to study the free radical scavenging activity by superoxide scavenging assay method. It was found that aqueo...

Objective: To study central nervous system activity of ethanolic extract of leaves of Calotropis gigantea (C. gigantea) (Asclepiadaceae), such as anticonvulsant, sedative and muscle relaxation activity. Methods: The ethanolic extract of C. gigantea administered orally in experimental animals at different doses 100, 200 and 500 mg/kg body weight. Th...

To study the in vivo anti-inflammatory activity of Tabernaemontana divaricata leaf extract on male albino mice. Aqueous decoction and methanol leaf extracts were tested for their ability to reduce croton oil-induced edema in the mouse ear after topical application. The methanol leaf extract dose-dependently inhibited the croton oil-induced ear edem...

Aim: The present study was undertaken with a view to validate the traditional use of Boerhaavia diffusa (BEE) root and Silybum marianum (SME) seeds in combination as a hepatoprotective agent against non-alcoholic fatty liver disease. Materials and Methods: The alcoholic extracts of BEE roots (150 mg/kg, p.o.) and SME (150 mg/kg, p.o.) seeds were ad...

Objective To evaluate three formulations of ‘Chandanasava’ [commercially made by Baidyanath, Dabur and test (prepared in-house)] for anti-ulcer activity.Methods The activity was evaluated in Albino wistar rats against ethanol induced, aspirin induced, cold restraint induced and pylorus ligation induced gastric ulcer models. The formulations were ad...

Objective Antioxidant capacities and phenolic contents of Gallic Acid isolated from plant Caesalpinia decapetala were investigated. Caesalpinia decapetala is a plant used to treat burns, biliousness and stomach disorders.Methods The antioxidant activity was estimated by the ABTS and DPPH methods. The total phenolic was measured using Folin-Ciocalte...

The present study is an attempt to enhance the dissolution profile, absorption efficiency and bioavailability of water insoluble drugs, such as curcumin. A novel "Powder Solution Technology" involves absorption and adsorption efficiency, which makes use of liquid medications, admixed with suitable carriers, coating materials and formulated into a f...

Godanti bhasma is an ayurvedic herbal mineral formulation used as antiulcer and antipyretic drug in Indian traditional systems of medicine. Godanti bhasma was evaluated for its toxicity, antiulcer and antipyretic activity in experimental animals. The experimental paradigms used for antiulcer activity were cold restraint stress induce ulcer model an...

The effect of 50% ethanol extract of D. extensa leaves on reproduction was studied on male rats. The study was divided into four groups of five animals each. The first groups (I) received vehicle alone to serve as control. The second, third and fourth groups(II, II and IV) of animals were administered the leaf extract daily 50mg/kg body weight, po,...

Objective To evaluate anti-diarrhoeal activity of aqueous and alcoholic extract of the leaves of Murraya koenigii (M. koenigii)by using models of castor oil induced diarrhoea, charcoal meal test and PGE2 induced diarrhoea.Methods Alcoholic extract (400 mg/kg) and aqueous extract (200 mg/kg) of leaves of Murraya koenigii were used with loperamide as...

Objective Pharmacognostic Screening and evaluate the in-vitro free radical scavenging activity of roots Acacia leucophloea.Methods Pharmacognostic Standardization, Physico-chemical evaluation of the roots of Acacia leucophloea was carried out to determine its macro-and microscopical characters and also some of its quantitative standards. Microscopi...

Objective To evaluate the antidiarrhoeal effect of alcoholic extract of Rotula aquatica by using different experimental models.Methods Antidiarrhoeal effect was evaluated by castor oil induced diarrhea, charcoal meal test and PGE2 induced diarrhea. Loperamide (2 mg/kg) and atropine (0.1mg/kg) were used as standard drugs. Alcoholic extract was used...

Acacia leucophloea (Mimosoideae) is native to Southeastern Asia. This tree species has been of interest to researchers because it is a medicinal plant employed in the Indian indigenous system of medicine. Pharmacognostic standardization, physico-chemical evaluation of the roots of Acacia leucophloea was carried out to determine its macro-and micro-...

Different novel Schiff bases derivatives were synthesized by a series of reactions. Isatin & 5-chloroisatin (1a-b) were condensed with thiosemicarbazide (2) to yield different thiosemicarbazones (3a-b) which were further cyclised to form corresponding Thia-3, 4, 9-triaza-fluoren-2-ylamines (4a-b). These were subjected to react with substituted alde...

Terminalia chebula Retz. (Combretaceae) is a medium-sized tree that grows in the wild throughout India. T. chebula has been extensively used in Ayurveda, Unani, and homoeopathic medicine. The fruit has been used as a traditional medicine for a household remedy against various human ailments. Traditionally T. chebula is used to cure chronic ulcer, g...

The anti-ulcer activity of Aqueous extract of the leaves of Murraya koenigii was evaluated by using models of acute gastric lesions induced by ethanol induced, asprin induced, cold restrain stress and pylorus ligation in rats. Animals pretreated with doses of 200 mg/kg and 400 mg/kg of Aqueous extract showed significant reduction in lesion index, t...

In order to scientifically apprise some of the anecdotal, folkloric, ethno medical uses of celosia argentea, the present study was undertaken to examine the antidiarrhoeal properties of alcoholic extract of leaves of Celosia argentea on diarrhoea by using different experimental models. Anti-diarrhoeal effect was evaluated by castor oil induced diar...