
Pratyush PorelIndo Soviet Friendship College of Pharmacy · Department of Pharmacology
Pratyush Porel
M.Pharm (Pharmacology)
Research Scholar
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3
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Introduction
Skills and Expertise
Publications
Publications (3)
Hypoxia-inducible factor 1α (HIF-1α) is a crucial transcription factor that regulates cellular responses to low oxygen levels (hypoxia). In Alzheimer’s disease (AD), emerging evidence suggests a significant involvement of HIF-1α in disease pathogenesis. AD is characterized by the accumulation of amyloid-beta (Aβ) plaques and neurofibrillary tangles...
Rationale
The endocannabinoid system (ECS) belongs to the G protein-coupled receptor family of cell membranes and is associated with neuropsychiatric conditions, and neurodegenerative diseases. Cannabinoid 2 receptors (CB2) are expressed in the central nervous system (CNS) on microglia and subgroups of neurons and are involved in various behavioura...
People were afflicted with a variety of illnesses prior to the revolution, and there was no access to medications sufficiently, at that time herbal agents fulfilled the demand for medications. In these modern days due to the huge side effects as well as drug resistance of marketed drugs, the demand for herbal medicines is increasing. We are all bus...