Pratima Khandelwal

New Horizon College of Engineering · Department of Biotechnology

The present study optimized the submerged fermentation conditions of Pediococcus pentosaceus Sanna 14 culture to improve bacteriocin yield by applying response surface methodology (RSM) and hybrid artificial neural networkgenetic algorithm (ANN-GA). A full factorial central composite design (CCD) of RSM was applied to assess the effect of four prin...

Are Lactic Acid Bacteria the bugs of the millennium? These surely are one of the highly pragmatic bugs of the millennium due to their diversity of metabolism, making them the most important group of bacteria in the production of traditional and modern fermented food products, their potential use in health and disease when used as probiotics or even...

A group of Gram-positive, non-spore forming, non-motile, non-respiring bacteria produces variety of antimicrobial compounds i.e lactic acid, acetic acid, ethanol, formic acid, fatty acids, hydrogen peroxide and bacteriocins; are considered to be Lactic acid bacteria (LAB). Due to the GRAS status and brad spectrum antibiotic nature, among the other...

Pediococcus pentosaceus strain Sanna-PK14 16S ribosomal RNA gene, partial sequence GenBank: MF183113.1

Rhizopus oryzae 18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1 and 5.8S ribosomal RNA gene, complete sequence; and internal transcribed spacer 2, partial sequence

Are Lactic Acid Bacteria the bugs of the millennium? These surely are one of the highly pragmatic bugs of the millennium due to their diversity of metabolism, making them the most important group of bacteria in the production of traditional and modern fermented food products, their potential use in health and disease when used as probiotics or even...

Lactic Acid Bacteria (LAB) known to produce bacteriocins; a small, ribosomally synthesized antimicrobial peptides considered as next generation antibiotics due to the broad spectrum antibiotic nature. Scanty research was reported on the isolation and screening of different LAB species with high bacteriocin yield. With this lacuna the present st...

Staphylococcus sp. strain warneri 16S ribosomal RNA gene, partial sequence Isolation of Bacteriocin producing species from south Indian pickles

Bacillus sp. strain cereus 16S ribosomal RNA gene, partial sequence

Weissella sp. strain confusa 16S ribosomal RNA gene, partial sequence GenBank: MF480335.1

Lactic Acid Bacteria (LAB) known to produce bacteriocins; a small, ribosomally synthesized antimicrobial peptides considered as next generation antibiotics due to the broad spectrum antibiotic nature. Scanty research was reported on the isolation and screening of different LAB species with high bacteriocin yield. With this lacuna the present study...

Chlorella rotunda 18S ribosomal RNA gene, partial sequence

Aspergillus sp. is known to produce cholesterol reducing drug-lovastatin. Lovastatin is a naturally occurring drug found in food such as red yeast rice (red rice koji or red fermented rice, red koji rice, red koji rice, anka, or ang-kak). Lovastatin (mevinolin) was the first hypocholesterolemic drug to be approved in 1987 by Food and Drug administr...

Objectives: Microalgae are unicellular photosynthetic organisms that assimilate lipids, which can be converted in to Biofuels. Microalgae help to mitigate carbon dioxide, because of their photosynthetic properties and utilize it to produce lipids. Microalgae biomass is a zero waste generation, as every part of the biomass is utilized to generate ot...

A quinine epoxide called terreic acid a secondary metabolite produced by the fungus Aspergillus terreus, is considered to be the “next generation antibiotic” due to its broad range antibiotic specificity. The antibiotic property of terreic acid was recognized more than 60 years ago. Previously many researchers were attempted different techniques an...

Objective: The present investigation aimed towards the strain improvement of lovastatin maximum yielding wild-type fungal strains (Aspergillus terreus-MTCC 11045, Aspergillus terreus-MTCC 11395 and Aspergillus flavus-MTCC 11396) through physical mutagenesis by applying UV random mutations. Methods: Revival of fungal cultures on PDA plates followed...

LACUNAE  Screening of new microalgae species was not reported.  No research document was found on optimization of microalgae growth conditions to enhance the yield of lipid and biomass content using Artificial Neural Network.  Scanty research was reported on production of value added products from the lipid extracted Microalgal biomass leading t...

Fluoride is a naturally occurring element in water systems and enters food chain mostly through drinking water. The WHO permissible limit of fluoride in water is 1.0 mg/l. At < 1.0 mg/l, it inhibits dental caries, at > 1.0 mg/l causes molting of teeth, lesion of endocrine glands, thyroid, liver and other organs. At still higher concentration (3-6 m...

Traditional oriental fermented foods namely soy sauce, miso, vinegar, red rice vinegar, pickled tofu and Ang-kak were becoming increasingly popular in different parts of India and shall be used for isolation of hypolipidemic agent, lovastatin producing representative fungi. Existing food grade (GRAS) fungi, Monascus sp were known to produce lovasta...

Attempts were made to prepare synbiotic yoghurt-cheese having functional attributes of both prebiotics and probiotics. Firstly, the conditions for the preparation of prebiotic yoghurt were optimized in order to determine the optimal level of prebiotic ingredients - raftiline (the fat replacer), raftilose (the sugar replacer), oat fiber and honey as...

Artificial Neural Network (ANN) is a computerized program designed to simulate the process in which the Central Nervous System (CNS) functions. In a recent time ANN being increasingly used in biotechnology and pharmaceutical research to predict the non-linear relationship between casual factors and response variables. ANN has a remarkable ability t...

Submerged cultures (SmF) of filamentous fungi ('Aspergillus terreus, Aspergillus flavus') are widely used to produce commercially important metabolite lovastatin. Limited investigations have been made on optimization of the different nutrients and process parameters using standard optimization methods. No previous work has used statistical analysis...

6. Upendra R.S, Pratima Khandelwal, Priyanka. S, Jagadish M L and Nandhini N.J.

Aspergillus terreus, Aspergillus oryzae and Monascus sp are known to produce cholesterol reducing drug- Lovastatin. It is presently available only as a drug with some after-effects. Scanty research work has been reported on the production and optimization of lovastatin based fermented foods by using underutilized substrates. Hitherto, no food syste...

Pimenta dioica is a variety of sweet pepper used as a spice and its leaves are used for traditional culinary purpose. Epiphyllum oxypetalum is a species of cactus and can be used as a substitute for digitalis. Scanty work has been reported on the phytochemical properties, assessment of nutritive value and bio-therapeutical potentials of these two i...

Low-alcoholic beverages, especially those produced from fruits, are increasing in demand and are being consumed in the form of table beverages. Present investigation features development of such new table beverages using the underutilized regional millets- finger millet (ragi) and pearl millet (bajra). Alcoholic fruit beverages (fruits wines) are c...

Epiphyllum oxypetalum is a species of cactus and one of the most commonly grown of the Epiphyllum species. It is one of the under-utilized resources available in the tropical regions of the globe and can be used as a substitute for digitalis. The Shoshone Indian tribe calls the night blooming Cereus "Pain in the heart" and used it for heart pain. S...

Culturing the individual plant cells, tissues (explants) and organs in laboratory or in vitro on synthetic media (MS media) under aseptic conditions is a usual process in plant tissue culture studies. The medium is rich in nutrients, also supports the growth of variety of microorganisms especially bacteria and fungi, which causecontamination of the...

Commercial interest in functional foods containing probiotic strains has consistently increased due to the awareness of gut health. Recent advancements are leading to development of synbiotic foods, containing prebiotics and probiotics bearing synergistic effects of the two. Thus, in present study, synbiotic acido-philus milk was developed satisfyi...

All-spice (pimenta) is one of the under-utilized resources available in the tropical regions of the globe. It is a variety of sweet pepper used as a spice and its leaves are used for traditional culinary purpose. Researchers have studied the antioxidant potentials of the berries of the plant, but no documented work is reported on its stem, leaf and...