Prashant Sakharkar

Prashant Sakharkar
Roosevelt University · College of Pharmacy

PharmD, MPH, HEOR Fellowship

About

46
Publications
12,142
Reads
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384
Citations
Citations since 2017
23 Research Items
309 Citations
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20172018201920202021202220230204060
20172018201920202021202220230204060
20172018201920202021202220230204060
Additional affiliations
August 2012 - August 2016
Roosevelt University
Position
  • Professor (Assistant)
September 2010 - August 2012
Western University of Health Sciences
Position
  • Fellow
August 1994 - July 2000
Institute of Pharmaceutical Education and Research
Position
  • Lecturer

Publications

Publications (46)
Article
Full-text available
Background: Several instruments are used for measuring functional limitations among rheumatoid arthritis (RA) patients. However, these instruments are incongruously assessed for their psychometric properties. The National Health and Nutritional Examination Survey (NHANES) uses a generic questionnaire to assess the activities of daily living (ADL) t...
Article
Full-text available
Background: Health disparities and mental health issues have not been fully explored among sexual minorities. This study aims to examine health disparities and severity of depression among sexual minorities using a nationally representative sample of the US population. Methods: The National Health and Nutrition Examination Survey (NHANES) data from...
Article
Full-text available
The existing literature is limited on the prevalence of depression among people with respiratory conditions and person-level factors that are associated with increased healthcare utilization and expenditures. The aim of this study was to explore the prevalence, pattern of healthcare use, and expenditures in noninstitutionalized individuals having c...
Article
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To examine the association between uric acid levels and liver enzyme functions amongst adults with hyperuricemia and gout in the United States. The National Health and Nutrition Examination Survey (NHANES) data from 2007 to 2016 was used to study the research objective. Data were analyzed for descriptive statistics and for differences using the t t...
Article
Full-text available
Purpose: Hyperglycemia is the hallmark of various types of diabetes and considered to be a risk factor for several chronic disorders including liver function. Though liver is a dynamic organ, incessant glucotoxicity can lead to altered liver function. The goals of the present study were to examine the association between diabetes with liver functi...
Article
Full-text available
Objective: Anticoagulation management with warfarin is a familiar challenge seen in primary care settings. A greater time in the therapeutic range (TTR) has shown improved health benefits in patients treated with warfarin for atrial fibrillation. The aim of this study was to assess the level of anticoagulation control achieved with warfarin therapy...
Article
Full-text available
Purpose: Although transplantations are associated with an increased risk of post-transplantation infections, they greatly improve life expectancy and patients' quality of life. Cytokine genes play an important role in the success of transplants due to their immunological functions. A systematic review was conducted to evaluate cytokine gene polymo...
Article
Full-text available
Objective: Anticoagulation management with warfarin is a familiar challenge seen in primary care settings. A greater time in the therapeutic range (TTR) has shown improved health benefits in patients treated with warfarin for atrial fibrillation. The aim of this study was to assess the level of anticoagulation control achieved with warfarin therapy...
Article
Full-text available
Introduction: The epidermal growth factor receptor (EGFR) plays a prominent role in cancer cell proliferation and metastasis in non-small-cell lung cancer (NSCLC). Targeted cancer therapies include agents that block tumor-specific molecular targets and thereby interfere with tumor growth, progression and metastasis. This study focuses on a systemat...
Article
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Background To examine the association between low-density lipoprotein (LDL) and high-density lipoprotein (HDL) levels and liver enzyme functions. Methods The National Health and Nutrition Examination Survey (NHANES) data from 1999 to 2012 was used to examine the association between liver enzymes and lipid levels amongst adults in the United States...
Data
The Supplemental Tables 1(a) and 1(b) illustrate the association of demographic characteristics such as age, gender, and race/ethnicity with different lipid biomarkers such as LDL, HDL, and triglyceride ranges. The Supplemental Table 1(c) highlights the association of demographic characteristics with ALT and AST.
Article
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Many herbal products are harmless or possess minimal toxicity, whereas, some contain toxic ingredients that may not be identified due to lack of quality control or not listed on the label. Over the years, several case reports and studies have documented that herbal medications may contain ingredients that are toxic. Several studies have documented...
Article
Full-text available
Vitamin D deficiency leads to poor bone development and general health. Newly converted calcitriol binds to the VDR protein, as encoded for by the VDR gene. VDR is expressed in most tissues of the body and there are several forms of VDR genes depicting polymorphism. There are four most common polymorphic forms found within the VDR gene are and thes...
Article
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Objective: Little knowledge is available on the antimicrobial and antioxidant properties of Coccina grandis fruits and no study has reported on its cell proliferative property. The aim of this study was to examine the antimicrobial, antioxidant and cell proliferative property of fruits of C. grandis. Materials and methods: Fruits of C. grandis w...
Article
Full-text available
Objective. To implement and evaluate an active-learning, team-based assignment centered on anticancer agents for the integration of basic science and pharmacotherapeutic principles. Methods. Student teams were assigned a specific anticancer agent and were expected to answer a series of questions on the written section of the assignment, followed by...
Research
Full-text available
Itankar, P. R., Sakharkar, P. R., & Chandewar, et al. (2001). Estimation of arsenic content in some Ayurvedic formulations. Hamdard medicus, 19, 95-97.
Article
Full-text available
Objective: To determine the relationship of determinants such as age, ethnicity, education and sexual behaviour with repeat teenage pregnancy and to determine the impact of 'Providing Access to Continued Education' (PACE) Programme in reducing repeat teenage pregnancy amongst its participants in The Bahamas. Subjects and methods: This retrospect...
Article
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The extant literature reveals a lack of psychometrically validated tools measuring patient satisfaction with pharmacist clinical services. The Patient Satisfaction with Pharmacist Services Questionnaire (PSPSQ 2.0) was developed to address this need using a mixed methods approach. To assess the psychometric properties of the PSPSQ 2.0, an instrumen...
Article
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Despite the potential deleterious impact on patient safety, environmental safety and health care expenditures, the extent of unused prescription medications in US households and reasons for nonuse remain unknown. To estimate the extent, type and cost of unused medications and the reasons for their nonuse among US households. A cross-sectional, obse...
Article
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Rationale and aim To examine preference of the elderly for adding indication (medication use/purpose) to prescription label, reasons for their preference and its association with demographic characteristics. Methods A convenience sample of 143 patients of age 65 or older, who took at least one prescription medication every day were interviewed usin...
Article
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Background Cytomegalovirus (CMV) is the most common cause of viral infection, causing morbidity and mortality among renal transplant recipients (RTRs). Cytokines such as tumor necrosis factor-alpha (TNF-α), interleukin-10 (IL-10), and interferon-gamma (IFN-γ) have been shown to possess antiviral properties, and their polymorphisms are associated wi...
Article
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BK virus nephropathy is one of the most common viral infections that affect up to 10% of renal transplant recipients (RTRs), causing allograft dysfunction and graft loss. Interferon-gamma (IFN-γ) gene polymorphisms have been associated with parvovirus B19, hepatitis C virus, HIV-1/AIDS infection, cytomegalovirus viremia, and disease. IFN-γ is known...
Article
Full-text available
Objectives To (1) describe the current status of instruction and assessment of communication skills and (2) identify potential changes being considered in US and Canadian pharmacy schools. Methods A cross-sectional, web-based survey was conducted of faculty who teach and/or oversee communication curricula. Results Seventy nine of 137 schools comp...
Article
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Background: The dimeric NF-κB transcription factors play critical roles in diverse cellular processes including adaptive and innate immunity, cell differentiation, proliferation and apoptosis. It regulates the expression of numerous genes that play a key role in the inflammatory response during kidney allograft rejection. This study aims to determ...
Article
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Polymorphism of genes encoding components of the vitamin D pathway including vitamin D receptor (VDR) and vitamin D binding protein (VDBP), have been widely explored due to the complex role played by vitamin D in renal transplant outcomes. In this study, we investigated whether polymorphisms of genes encoding VDR and VDBP were associated with allog...
Article
Full-text available
In the context of comparative research, the World Health Organisation (WHO) proposed to categorise the risk for alcohol-related acute and chronic harm according to patients' average daily alcohol consumption. OBJECTIVES: To estimate utility scores associated with each category of the WHO drinking risk-level classification in patients with alcohol d...
Article
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The in vitro antifungal activity of Calendula officinalis flower extracts have been investigated against Aspergillus niger, Rhizopus japonicum, Candida albicans, Candida tropicallisand Rhodotorula glutinis. The extracts of Calendula officinalis showed high degree of activity against all test fungi. The inhibitory effects of extracts are very close...

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