Pradip Bhattacharya

Rajendra Institute of Medical Sciences RIMS RANCHI · Critical Care Medicine

How to cite this article: Khilnani GC, Tiwari P, Mittal S, Kulkarni AP, Chaudhry D, Zirpe KG, et al. Guidelines for Antibiotics Prescription in Critically Ill Patients. Indian J Crit Care Med 2024;28(S2):S104–S216.

Gender disparity in Critical Care Medicine (CCM) persists globally, with women being underrepresented. Female Intensivists remain a minority, facing challenges in academic and leadership positions at the workplace and within academic societies. The Indian Society of Critical Care Medicine (ISCCM) recognized the need for addressing issues related to...

Purpose The purpose of our meta-analysis was to look at the impact of modified nutrition risk in the critically ill (mNUTRIC) on mortality in patients with critical illness. Materials and methods Literature relevant to this meta-analysis was searched in PubMed, Web of Science, and Cochrane Library till 26 August 2023. Prospective or retrospective...

Background Peripheral venous access may become sometimes challenging in critically ill patients due to various reasons. Cannulation of deep upper limb veins using a long peripheral venous catheter (L-PVC) may be feasible under ultrasound (USG) guidance in such patients. Aim: To test the efficacy and safety of L-PVC. The main objective of this study...

Objectives: Statins have significant therapeutic implications in patients having high cardiovascular risk or preexisting cardiovascular disorders. Exploring the correlation between statin therapy and outcomes in coronavirus disease 2019 (COVID-19) patients is the objective of the current meta-analysis. Data sources: PubMed, Web of Science, Google S...

Complete understanding and future management of COVID‑19 pandemic requires the initiation of activities for proper archiving of COVID‑19 patient data. Internal imaging data can be critical to current and future management of COVID‑19.

Background Acute hypoxemic respiratory failure is the most common complication of COVID 19 infection. Newer ways for oxygen therapy were explored during this pandemic. High flow nasal oxygenation (HFNO) emerged as a novel technique for oxygenation and prevented the need for invasive mechanical ventilation during hypoxia among COVID patients. Using...

Background: Coronavirus disease-2019 (COVID-19) is prone to acute hypoxemic respiratory failure (AHRF). Because tracheal intubation is associated with a higher risk of death in these patients, AHRF employs high-flow nasal oxygen therapy (HFNOT). The goal of this study was to assess the effect of HFNOT on oxygenation status as well as different pre...

The most common cause of postoperative fever is infection. Other causes include cancer, iatrogenic causes, venous thromboembolism, secondary to prosthetic implants, and pyrexia of unknown origin. Here, we describe five cases of opioid-induced pyrexia. In all cases, an injection of morphine was given for postoperative analgesia and all those patient...

Aim and background Pre-extubation fasting and the evacuation of gastric contents using a nasogastric (NG) tube is often practiced in critically ill patients to protect the lungs from the risk of aspiration. Gastric ultrasound (GUS) is an excellent bedside modality to assess the gastric volume and content before planned tracheal extubation and may p...

and written informed consent, a prospective observational study was performed over a period of 3 months at the COVID intensive care unit of a government institute-hospital in east India. Adult patients (aged >18 years) with confirmed COVID-positive status (SARS-CoV-2 detected in nasopharyngeal swab by real-time reverse transcription-polymerase chai...

Background: Coronavirus disease 2019 (COVID-19) in the last few months has disrupted the healthcare system globally. The objective of this study is to assess the impact of the COVID-19 pandemic on the psychological and emotional well-being of healthcare workers (HCWs). Materials and methods: We conducted an online, cross-sectional, multinational su...

Context: Shivering is one of the most commonly recognized complications of the central neuraxial blockade. For optimal perioperative care, control of post-spinal anesthesia shivering is essential. Aims: The present study designed to compare the clinical efficacy, hemodynamic and side effects of nalbuphine and tramadol for control of post‑spinal ane...

The components through which ARDS causes lung damage not fully known yet, however, conceivable contributors include a cytokine discharge disorder set off by the viral antigen-induced, drug-induced pulmonary toxicity, high airway pressure and hyperoxia-prompted intense lung damage following mechanical ventilation. Our findings or personal views in o...

Background. Telavancin is a lipoglycopeptide bactericidal against gram-positive pathogens. Methods. Two methodologically identical, double-blind studies (0015 and 0019) were conducted involving patients with hospital-acquired pneumonia (HAP) due to gram-positive pathogens, particularly methicillin-resistant Staphylococcus aureus (MRSA). Patients we...

Context: Shivering is one of the most commonly recognized complications of the central neuraxial blockade. For optimal perioperative care, control of postspinal anesthesia shivering is essential. Aims: The present study designed to compare the clinical efficacy, hemodynamic parameters, and side effects of nalbuphine and tramadol for control of p...

Purpose: The DIANA study aimed to evaluate how often antimicrobial de-escalation (ADE) of empirical treatment is performed in the intensive care unit (ICU) and to estimate the effect of ADE on clinical cure on day 7 following treatment initiation. Methods: Adult ICU patients receiving empirical antimicrobial therapy for bacterial infection were stu...

The Intensivist was called to evaluate a female patient in emergency department who was known to have advanced emphysema. She was getting oxygen through a nasal cannula at 6 L/min. The nurse says that she has become drowsy and less responsive since the oxygen was given to her an hour ago. Her ABG results on the oxygen show the following: PaO 2 , 84...

Background: Indian Society of Critical Care Medicine (ISCCM) guidelines on Planning and Designing Intensive care (ICU) were first developed in 2001 and later updated in 2007. These guidelines were adopted in India, many developing Nations and major Institutions including NABH. Various international professional bodies in critical care have their o...

Background and Objective: WhatsApp is a user-friendly instant messaging application for smartphones through which text, images, video and audio messages can be exchanged without any additional charges. Although its efficacy as a tool for academic purposes has been published in various medical and other educational journals, studies analyzing its us...

Introduction-Resistant strains of Enterobacteriaceae and nonfermenters have emerged recently due to many variable reasons with the use of carbapenems. Resistance to carbapenems is mostly due to enzymes called carbapenemase. Various studies have been conducted to evaluate the prevalence of carbapenemase producers. Aims-The present retrospective stud...

How to cite this article: Khilnani GC, Zirpe K Evidence Statement Time-dependent antibiotics require drug concentrations greater than the minimum inhibitory concentration (MIC) for a certain period between doses, which usually ranges from 40 to 50% of the inter-dose interval for their best action. Continuous infusions are preferred over extended in...

Background In low- and middle-income countries such as India, where health systems are weak, the number of available Critical Care Unit (Intensive Care Unit [ICU]) beds is expected to be low. There is no study from the Indian subcontinent that has reported the characteristics and distribution of existing ICUs. We performed this study to understand...

Guillain-Barre Syndrome (GBS) is an important cause of acute neuromuscular paralysis with disabling consequences. Early diagnosis and aggressive treatment using immunotherapy and multidisciplinary care can better the prognosis. The objective of this study was to analyze the clinical outcomes and recovery in patients with GBS treated with TPE as an...

Background: Burns are a common injury in developing countries creating a major public health problem and are associated with significant morbidity and mortality. Being a tertiary care referral center we evaluated all burn cases referred to our center during last two year period. Aims and Objectives: Our objective of this retrospective analysis is t...

Road Traffic Accident (RTA) is one among the top five causes of morbidity and mortality in SouthEast Asian countries as well as India1 and is the third major unnatural preventable deaths amongst all. Our aim is Retrospective evaluation of factor's involved and common associations in victims of RTA in a state highway. This retrospective analysis was...

Background:The study was designed to ascertain the utility of lumbar drain in achieving brain relaxation intraoperatively in patients undergoing intra cranial vascular aneurysmal surgeries. Materials and methods: This prospective non-randomized study was conducted on 40 patients. After standard intravenous induction and securing the airway with end...

These guidelines, written for clinicians, contains evidence-based recommendations for the prevention of hospital acquired infections Hospital acquired infections are a major cause of mortality and morbidity and provide challenge to clinicians. Measures of infection control include identifying patients at risk of nosocomial infections, observing han...

Clinically significant venous air embolism (VAE) occurs most often during sitting craniotomies and spinal surgeries when venous sinuses are open at a level above the heart. VAE is also a known complication of caesarean delivery and various other surgical procedures. In intensive care setup multilumen catheters are widely used. It happens most commo...

Huntington's chorea is a very rare degenerative disease of the nervous system. Reported anaesthesia experience with Huntington's chorea is very limited. Patients with Huntington's chorea are at higher risk of intraoperative complications. Successful anaesthetic management of a case of Huntington's chorea posted for a urological procedure is present...

The physiology of the female is substantially altered during pregnancy. Pregnant patients may also present with various kinds of cardiac diseases and the manifestations of these diseases may get worsened, and can be deleterious for both mother and fetus. Cardiac surgery with extra corporeal support during pregnancy has been associated with elevated...