Prabodh Satyal

Aromatic Plant Research Center

Manuka essential oil has long been used in traditional medicine, though the effects of the oil on cancer cells have limited studies. The goal of this project was to treat cancer cell lines with manuka essential oil at different concentrations and to ascertain the effects on the cell proliferation of normal fibroblast (CUA-4) and on fibrosarcoma (HT...

The dietary supplement industry is a growing market with a variety of suppliers, producers, and distributors in terms of size and quality. Because of the little amount of regulation placed on the dietary supplement industry compared to the pharmaceutical industry in the United States, there is less pressure on supplement companies ensure that their...

Endocrine disruptors are molecules that can interfere with the proper functioning of the endocrine system and lead to harmful effects in living organisms. This review focuses on the impact of synthetic fragrances, which are commonly found in personal care and household products, on the endocrine system. The article discusses the different types of...

In this study, essential oils and waste hydrosols of leaves of Ocimum tenuiflorum in four different geographical locations were extracted by hydrodistillation method and using gas chromatography / mass spectrometry (GC/MS) for chemical composition analysis. All four essential oil samples contained the main components (E)‐β‐caryophyllene (27.8‐49.0%...

The oral microbiome is a diverse and complex ecosystem essential for maintaining oral and systemic health. Our study is the first to define the oral microbial community in Egyptian young adults and investigate the effects of natural antimicrobials on the oral microbiome. SuperMint (SM) is a proprietary blend of peppermint, Japanese mint, bergamot m...

Mycetoma, a neglected infection of subcutaneous tissues, poses a significant health burden, especially in tropical regions. It is caused by fungal (eumycetoma) and bacterial (actinomycetoma) pathogens, with current treatments often providing unsatisfactory outcomes. This study aims to discover novel broad-spectrum antimicrobial agents to circumvent...

Endocrine disruptors are molecules that can interfere with the proper functioning of the endocrine system and lead to harmful effects in living organisms. This review focuses on the impact of synthetic fragrances, which are commonly found in personal care and household products, on the endocrine system. The article discusses the different types of...

Objective Although cancer therapy suppresses recurrence and prolongs life, it may be accompanied by strong side effects; thus, there is a strong demand for the development effective treatments with fewer side effects. Cancer therapy using plant-derived essential oils is attracting attention as one promising method. This study investigated the antit...

The oral microbiome is a diverse and complex ecosystem essential for maintaining oral and systemic health. Our study is the first to define the oral microbial community in Egyptian young adults and investigate the effects of natural antimicrobials on the oral microbiome. SuperMint (SM) is a proprietary blend of peppermint, Japanese mint, bergamot m...

Essential oils (EOs) from Citrus sinensis (Rutaceae) possess diverse biological activities. However, a comprehensive comparison of their chemical composition and bioactivity across different plant parts has not been studied yet. The current research comparatively assesses the yield, chemical composition, chiral distribution, antioxidant properties,...

As part of our continuing interest in the essential oil compositions of gymnosperms, particularly the distribution of chiral terpenoids, we have obtained the foliar essential oils of Chamaecyparis lawsoniana (two samples), Thuja plicata (three samples), and Tsuga heterophylla (six samples) from locations in the state of Oregon, USA. The essential o...

Background/Objective: Wyethia amplexicaulis (shiny mule's ears) and Wyethia helianthoides (white-head mule's ears) are conspicuous forbs growing in open hillsides and prairies at mid to upper elevations in the Intermountain West region of the United States. There have been no previous reports on the essential oil compositions of any Wyethia species...

In the search for new bioactive agents against the infectious pathogen responsible for the neglected tropical disease (NTD) mycetoma, we tested a collection of 27 essential oils (EOs) in vitro against Madurella mycetomatis, the primary pathogen responsible for the fungal form of mycetoma, termed eumycetoma. Among this series, the EO of Santalum alb...

As part of our interest in the volatile phytoconstituents of aromatic plants of the Great Basin, we have obtained essential oils of Ambrosia acanthicarpa (three samples), Artemisia ludoviciana (12 samples), and Gutierrezia sarothrae (six samples) from the Owyhee Mountains of southwestern Idaho. Gas chromatographic analyses (GC-MS, GC-FID, and chira...

The fatty acid (FA) compositions of thirty-nine vegetable oils and fats, including nangai nut, pili nut, shea butter, tamanu oil, baobab, sea buckthorn berry, Brazil nut, grape seed, black seed, evening primrose, passion fruit, milk thistle, sunflower, pumpkin seed, sesame, soybean, flax seed, kukui, red raspberry seed, walnut, chia seed, hemp seed...

Background/Objective: Arrowleaf balsamroot ( Balsamorhiza sagittata (Pursh) Nutt., Asteraceae) is a conspicuous forb growing in open hillsides and prairies at mid to upper elevations in the Intermountain West and Rocky Mountain regions. The plant is important forage for deer and elk and several Native American tribes used arrowleaf balsamroot as fo...

Pimenta dioica L. is one the most recognized species with diverse biological activities. In this study, in vitro activity and in vivo efficacy of essential oil from P. dioica (EO-Pd) was evaluated. The main compound was also included in the animal studies and its in silico prediction related to biological activities, molecular ligands, drug likenes...

Bridelia ferruginea Benth is a plant usually found in Savannah regions, used in ethno-medicine for treatment of dysentery, elephantiasis, intestinal and bladder disorder. Chemical compounds present in the leaf, twig, stem bark, stem wood and root wood of Bridelia ferruginea essential oils, their antioxidant and toxicity assays are been reported. Th...

Carrier oils are used with essential oils to dilute and enhance skin penetration. They are composed of fatty acids, triglycerides, monoterpenes, and sesquiterpenes and are added to reduce potency and odor. Carrier oils have pharmaceutical applications and reduce cytotoxicity. Solvent extraction is a common practice in the production of industrial-s...

Echinacea purpurea (L.) Moench is a medicinal plant commonly used for the treatment of upper respiratory tract infections, the common cold, sore throat, migraine, colic, stomach cramps, and toothaches and the promotion of wound healing. Based on the known pharmacological properties of essential oils (EOs), we hypothesized that E. purpurea EOs may c...

Blue lotus, also known as Nymphaea caerulea (Nymphaeaceae), is a water lily found globally in lakes and rivers. With its long history of use in Egyptian culture, blue lotus has been associated with spiritual rituals and health benefits. Nowadays, blue lotus is still consumed as a tea or tincture to induce relaxation and heightened spiritual awarene...

Diseases transmitted by mosquitoes and snails cause a large burden of disease in less developed countries, especially those with low-income levels. An approach to control vectors and intermediate hosts based on readily available essential oils, which are friendly to the environment and human health, may be an effective solution for disease control....

Background: Essential oils (EOs) are one of the most important groups of plant secondary metabolites responsible for their various biological activities. They also have wide applications as natural ingredients in many fields like the food, cosmetic, and medicine industries. This study was conducted to determine the chemical composition, enantiomeri...

Background Anthriscus caucalis is a non-native plant in North America with invasive potential. As part of our interests in essential oils of the Great Basin, a wild-growing sample of A. caucalis was collected in southwestern Idaho. Methods The essential of A. caucalis was obtained by hydrodistillation and analyzed by gas chromatographic methods (G...

Objective Although cancer therapy suppresses recurrence and prolongs life, it may be accompanied by strong side effects; thus, there is a strong demand for the development effective treatments with fewer side effects. Cancer therapy using plant-derived essential oils is attracting attention as one promising method. This study investigated the antit...

Leaves of Holodiscus dumosus were obtained from a wild-growing plant in southern Idaho. The leaf essential oil was obtained by hydrodistillation (0.151% yield) and analyzed by gas chromatography (GC-MS, GC-FID, and chiral GC-MS). The major components in the leaf oil were geraniol (17.4%), germacrene B (8.9%), (E)-β-caryophyllene (6.1%), α-cadinol (...

Background and Objective: Plumeria acuminata has a long history of use in traditional medicine which includes treatment of rheumatism, pruritic skin lesion, toothache, asthma, cracks on the feet sole crack, heart stroke, dysentery and diarrhoea. This study was designed to extract essential oils from the leaf, flower and root of P. acuminata, analys...

Frankincense is an oleo-gum-resin collected from wild Boswellia spp. trees, and widely used in perfumery, cosmetics, aromatherapy, incense, and other industries. Boswellia rivae, growing in Ethiopia, Somalia, and Kenya, is one source of frankincense, but is little-commercialized compared to species such as B. sacra, B. frereana, and B. papyrifera....

Grindelia squarrosa is an arid lands herb that has been used in Native American traditional medicine, is a potential source of pharmacologically active compounds, and has been explored as a source of biofuel. The purpose of this work was to examine the essential oil composition of G. squarrosa from southern Idaho. Gas chromatographic methods reveal...

Background: Rabbitbrush (Ericameria nauseosa) is a conspicuous member of plant communities in the deserts of western North America. The plant is an important winter forage for several ungulates in the region and has been used in Native American ethnopharmacology. Methods: Several specimens were collected from North Central Utah (8 samples) and Sout...

Conifers are of great economic value in terms of lumber production, important for construction and other uses such as pulp and paper. They are also important sources of essential oils. Conifer species have been vital to the ethnobotany and traditional herbal medicine of many different Native American groups. The objective of this work was to obtain...

Using essential oils to control vectors, intermediate hosts, and disease-causing microorganisms is a promising approach. The genus Croton in the family Euphorbiaceae is a large genus, with many species containing large amounts of essential oils, however, essential oil studies are limited in terms of the number of Croton species investigated. In thi...

Background/Objective: Big sagebrush (Artemisia tridentata Nutt., Asteraceae) is a conspicuous shrub growing in arid and semi-arid regions of intermountain western North America, from eastern Washington and Oregon, through Nevada, Idaho, and Utah, into northern Arizona and New Mexico, and east as far as the western Dakotas, and Colorado. At least th...

There is an ongoing interest to identify alternative pesticidal agents to avoid the chronic problems associated with synthetic pesticides. Essential oils have shown promise as botanical pest control agents. In the present study, the essential oils of four members of the Lamiaceae (Callicarpa candicans, C. erioclona, C. macrophylla, and Karomia frag...

Myoporum sandwicense A. Gray (naio) is one of the characteristic trees of Hawaiian montane–subalpine mesic forests. In this study, lab-distilled oils of M. sandwicense leaves, wood, and twigs growing on the island of Hawaii, as well as industrially produced wood oils, were characterized by gas chromatography–mass spectrometry (GC-MS). The lab-disti...

Cymbopogon species essential oil (EO) carries significant importance in pharmaceuticals, aromatherapy, food, etc. The chemical compositions of Cymbopogon spp. Viz. Cymbopogon winterianus (citronella) Cymbopogon citratus (lemongrass), and Cymbopogon martini (palmarosa) were analyzed by gas chromatography–mass spectrometry (GC-MS), enantiomeric distr...

ellow rabbitbrush (Chrysothamnus viscidiflorus) is native to the Great Basin of NorthAmerica and the plant was part of the traditional medicine of Native Americans in theregion. There has been very little previous work on essential oils of Chrysothamnus, andno reports on C. viscidiflorus essential oil. Therefore, the purpose of this work was toeval...

Background: Spanish sage ( Salvia officinalis subsp . lavandulifolia [Vahl] Gams) is historically an important medicinal plant with a myriad of uses. Methods: In this work, 11 S officinalis subsp. lavandulifolia essential oils (EOs) from Spain were prepared by steam distillation and characterized by gas chromatography-mass spectrometry (GC-MS) and...

Boswellia ogadensis is a critically endangered species of frankincense tree, restricted to a small area of the Shabelle river valley in southern Ethiopia. It has only been recorded from two botanical collecting trips, in 1972 and 2006, with no indication of the abundance, threats, or population status of the trees, and it was listed on the IUCN Red...

Introduction: Vitex doniana is used in traditional medicine for treatment of several ailments, including conjunctivitis, skin rashes due to measles or chickenpox, respiratory infections, and abdominal disorders and diarrhea. Methods: The leaf essential oil of V. doniana from southwestern Nigeria was obtained by hydrodistillation and analyzed by gas...

Mosquitoes, in addition to being a biting nuisance, are vectors of several pathogenic viruses and parasites. As a continuation of our work identifying abundant and/or invasive plant species in Vietnam for use as ecologically friendly pesticidal agents, we obtained the essential oils of Blumea lacera, Blumea sinuata, Emilia sonchifolia, Parthenium h...

Essential oils are promising as environmentally friendly and safe sources of pesticides for human use. Furthermore, they are also of interest as aromatherapeutic agents in the treatment of Alzheimer’s disease, and inhibition of the enzyme acetylcholinesterase (AChE) has been evaluated as an important mechanism. The essential oils of some species in...

Citrus essential oils are routinely adulterated because of the lack of regulations or reliable authentication methods. Unfortunately, the relatively simple chemical makeup and the tremendous price variations among Citrus varieties encouraged the interspecies adulteration of citrus oils. In this study, a sensitive UPLC-MS/MS method for the quantitat...

This study was conducted to examine the chemical constituents of Origanum majorana L. essential oils (EOs) that originate in Nepal, as well as their biological activities, antioxidant properties, and enantiomeric compositions. The EOs were extracted by the hydro-distillation method using a Clevenger-type apparatus and their chemical compositions we...

Pinus species are important in traditional medicine throughout their ranges, and pine essential oils are of interest in aromatherapy and as topical treatments. In this work, the leaf (needle) essential oils of Pinus ponderosa var. ponderosa and Pinus contorta subsp. contorta from Oregon and Pinus flexilis growing in Idaho, have been obtained by hyd...

Western flower thrips ( Frankliniella occidentalis ; Thysanoptera: Thripidae), or WFT, are a global pest of commercial crops, particularly those grown in greenhouses. Current management recommendations often involve judicious use of pesticides to which WFT have evolved multiple resistance phenotypes. Essential oils (EOs) have shown promise as a les...

Sweet Birch (Betula lenta) has several economic and medicinal uses. Very little is known about the chemical composition of B. lenta. In this study, the volatile compositions of the bark of B. lenta from authentic and commercial sources were assessed by gas chromatography-mass spectrom-etry (GC-MS) and gas chromatography-flame ionization detection (...

A comparative analysis of the chemical constituents present in twenty-one commercial and two lab-distilled frankincense (Boswellia carteri) essential oils was carried out using gas chromatography mass spectrometry (GC-MS) and chiral gas chromatography-mass spectrometry (CGC-MS) for authentication. Out of the twenty-one commercial samples, six were...