Pingchuan Zhang

Pingchuan Zhang
Pathologists Bio-Medical Labs

MD

About

20
Publications
2,266
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447
Citations
Citations since 2016
6 Research Items
225 Citations
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20162017201820192020202120220102030
Introduction
Pingchuan Zhang currently works at the Department of Pathology, Mayo Foundation for Medical Education and Research. Pingchuan does research in Cancer Research, Molecular Biology and Cell Biology. Their most recent publication is 'IgG4-Related Tubulointerstitial Nephritis'.

Publications

Publications (20)
Article
Introduction: Previous investigations have studied the importance of imprint cytology (IC) testing of core needle biopsy (CNB) from various organs. We have presented the largest series, to the best of our knowledge, of IC testing of CNB for patients with kidney tumors. Materials and methods: The present retrospective study (January 1, 2015, thro...
Article
Background: Proliferative glomerulonephritis with monoclonal IgG deposits (PGNMID) has been recognized as a distinct entity in recent years. To the best of our knowledge, all patients with PGNMID reported thus far were older than 20 years of age. We now report five cases of PGNMID in patients under 20 years of age. Methods: The clinical database...
Article
Immunoglobulin G4 (IgG4)–related disease (IgG4-RD) is a fibroinflammatory disorder that can involve nearly any organ. The disorder has increasingly become known as a distinct clinical entity during the last decade. IgG4-related tubulointerstitial nephritis (IgG4-TIN) is the most common manifestation of IgG4-RD in the kidney. Many patients with IgG4...
Article
Objectives Spindle cell lipomas (SCLs) are benign lipomatous neoplasms that classically arise in the posterior neck, upper back, and shoulders of older male patients. We sought to characterize the occurrence of this entity at nonclassic sites. Methods All cases of SCL arising at atypical sites were retrieved from our archives. Results Of 439 tota...
Article
-Vasculogenic cell-based therapy combined with tissue engineering is a promising revascularization approach destined at patients with advanced coronary artery disease, many of whom exhibit myocardial hibernation. However, so far no experimental data have been available in this context; we therefore examined the biopolymer-supported delivery of circ...
Article
Full-text available
Biomaterial-guided regeneration represents a novel approach for the treatment of myopathies. Revascularisation and the intramuscular extracellular matrix are important factors in stimulating myogenesis and regenerating muscle damaged by ischaemia. In this study, we used an injectable collagen matrix, enhanced with sialyl LewisX (sLeX), to guide ske...
Article
Full-text available
Although many regenerative cell therapies are being developed to replace or regenerate ischaemic muscle, the lack of vasculature and poor persistence of the therapeutic cells represent major limiting factors to successful tissue restoration. In response to ischaemia, stromal cell-derived factor-1 (SDF-1) is up-regulated by the affected tissue to st...
Article
Full-text available
Cell therapy for the treatment of cardiovascular disease has been hindered by low cell engraftment, poor survival, and inadequate phenotype and function. In this study, we added chitosan to a previously developed injectable collagen matrix, with the aim of improving its properties for cell therapy and neovascularization. Different ratios of collage...
Article
Clinical efficacy of cardiac cell therapy may be compromised by its target population, patients with endothelial dysfunction. In vivo inhibition by endothelial dysfunction has been demonstrated for protein angiogenesis but remains unclear for cell therapy. We examined whether hypercholesterolemia inhibits vasculogenic effects of transplanted human...
Article
Circulating progenitor cells home to and engraft to sites of ischemia, mediated in part by the adhesion molecule L-selectin; however, accumulation in tissues such as the heart is low. In this study, an acellular collagen-based matrix containing sialyl Lewis(X) (sLe(X)), which binds L-selectin, was developed in order to enhance the endogenous progen...
Article
Objectives: Following a cardiac event, circulating progenitor cells can home and engraft to sites of neovascularization, mediated in part by the adhesion molecule L-selectin; however, accumulation in the heart is low. We developed an acellular matrix containing the oligosac-charide sialyl Lewis X (sLe X ; 0.1mM), which binds L-selectin, in order to...
Article
The purpose of this study was to investigate whether an artificial matrix can help neonatal cardiomyocytes restore an injured heart in a rat model of myocardial infarction (MI). The left coronary arteries of female Sprague Dawley (SD) rats were ligated to create MI models. Ventricular cardiomyocytes from 1- to 3-day-old SD rats (both sexes) were is...
Article
To investigate whether injectable engineering heart tissue (EHT) can survive and improve heart function after transplantation into infarct area. Ventricular cardiomyocytes from 1-3 day-old Sprague-Dawley (SD) rats were isolated by using trypsin method, and then labeled and cultured. The left coronary of female SD rats was ligated to create a myocar...

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