Ping Deng

• Ph.D
• Professor (Full) at Cleveland State University

More Chinese companies are using cross-border merger and acquisition (M&A) to access and source strategic assets so as to address their competitive disadvantage. However, there is lack of research on the rationale for such strategic-asset-seeking M&A. This paper intends to address this critical issue from an institutional perspective. Building on i...

As more Chinese companies become engaged in foreign direct investment (FDI), particularly in industrial countries, a crucially important issue must be addressed: what is the motivation of Chinese outward FDI, and what is its rationale? Based on a detailed analysis of both primary and secondary data sources, this article argues that when investing i...

Thesis (Ph. D.)--Old Dominion University, 1998. Includes bibliographical references.

Over the past two decades, Chinese multinationals have made a huge amount of foreign direct investment abroad, making China one of the world's leading foreign investors. The phenomenon has not been widely studied from a business perspective, however. Given the increasing prominence of Chinese MNCs in global business, this study of both macro and mi...

This report examines the process of economic and financial integration in East Asia in the light of Europe's experience.� The report provides a comprehensive analysis of East Asian monetary and financial integration process (including a deep analysis of East Asia's response to the 1997-98 financial crisis), a comprehensive critical survey of the li...

The effects of neurotoxicant cadmium (Cd) exposure on brain development have not been well elucidated. To investigate this, we have herein subjected pregnant mice to low-dose Cd throughout gestation. Using single-cell RNA sequencing (scRNA-seq), we explored the cellular responses in the embryonic brain to Cd exposure, and identified 18 distinct cel...

Cadmium (Cd) is a neurotoxic contaminant that induces cognitive decline similar to that observed in Alzheimer's disease (AD). Autophagic flux dysfunction is attributed to the pathogenesis of AD, and this study aimed to investigate the effect of autophagy on environmental Cd‐induced AD progression and the underlying mechanism. Here, Cd exposure inhi...

Although adequate intake of manganese (Mn) is essential to humans, Mn in excess is neurotoxic. Exposure to extremely high doses of Mn results in "manganism", a condition that exhibits Parkinson-like symptoms. However, the mechanisms underlying its neurotoxic effects in Mn-induced parkinsonism pathogenesis are unclear. In this study, 8-week-old male...

Cadmium (Cd) is a heavy metal that has been widely reported to be linked to the onset and progression of breast cancer (BC). However, the mechanism of Cd-induced mammary tumorigenesis remains elusive. In our study, a transgenic mouse model that spontaneously develops tumors through overexpression of wild-type Erbb2 (MMTV-Erbb2) was constructed to i...

Chronic Cd exposure induces an inflammatory response that contributes to liver damage. In the present study, C57BL/6J mice (8 weeks) were administered CdCl2 (0.6mg/L) orally for 6 months, and the underlying mechanism of chronic Cd-induced hepatotoxicity was explored through the application of transcriptomics and metabolomics. Chronic Cd exposure in...

Doxorubicin (DOX) is an anthracycline antineoplastic agent that has limited clinical utility due to its dose-dependent cardiotoxicity. Although the exact mechanism remains unknown, inflammatory responses have been implicated in DOX-induced cardiotoxicity (DIC). In this study, we analyzed the transcriptomic, metabolomic as well as lipidomic changes...

Cadmium (Cd), which is considered an endocrine disruptor, has been linked to the onset of breast cancer (BC). Our recent study demonstrated that Cd-induced BC progression has a strong correlation with miR-374c-5p dysregulation. The aim of our work was to investigate other potential miRNAs involved in Cd-induced BC cell proliferation and metastasis....

Cadmium (Cd), a ubiquitous environmental contaminant, is deemed a possible aetiological cause of cognitive disorders in humans. Nevertheless, the exact mechanism by which chronic exposure to Cd causes neurotoxicity is not fully understood. In this study, mouse neuroblastoma cells (Neuro-2a cells) and primary hippocampal neurons were exposed to low-...

Paraquat (PQ) is the most widely used herbicide in the world and a well-known potent neurotoxin for humans. PQ exposure has been linked to increase the risk of Parkinson's disease (PD). However, the mechanism underlying its neurotoxic effects in PD pathogenesis is unclear. In our present study, C57BL/6J mice treated with PQ manifested severe motor...

690 篇 SSCI 期刊论文为样本， 通过文献计量分析、 因子分析和多维尺度分析，探索和识别了新兴市场跨国公 司国际扩张 研究领域的学科知识基 础， 发现 其由新兴市 场跨国公司国际扩张的动机 及影响因素、不同理论 视角、 新兴市场情 境 特征、 新兴市场跨国公司特征、 运营与决 策过程、 绩效等六个模块构成。 这六个知识基 础模块构 成一个包括新兴市场跨国公司国际扩张的"情境-理论基 础-前因-行为-后果" (C T A B C)知识框架。在此基 础上，通过 对 80 篇高被引文献的内容分析，从研究主题、 理论 视角和研究设计(包括文 献类型、 数据来源、 样本 特征)等三个方面揭示了新兴市场跨国公司国际扩张的研 究进 展，发掘现有研究不足，并以此 提出该领域未来的 研究方向，为后续研究...

Arsenic, a widely existing environmental contaminant, is recognized to be toxic to multiple organs. Exposure to arsenic results in liver damage via excessive production of reactive oxidative species (ROS). PIN1 regulates the levels of ROS. N-acetyl-L-cysteine (NAC) is an ROS scavenger that protects the hepatic functions. Whether PIN1 plays a regula...

Fluoride has received much attention for its predominant bone toxicity in the human body. However, the toxic mechanism of bone injury caused by fluoride exposure remains largely unclear. Bone marrow mesenchymal stem cells (BMSCs) are widely used as model cells for evaluating bone toxicity after environmental toxicant exposure. In this study, BMSCs...

Cadmium (Cd), a common environmental and occupational toxicant, is an important risk factor for hearing loss. After exposure, Cd accumulates in the inner ear and induces spiral ganglion neuron (SGN) degeneration; however, the underlying mechanisms are poorly understood. Dysfunctional autophagy has been implicated in many neurodegenerative diseases,...

Aging causes astrocyte morphological degeneration and functional deficiency, which impairs neuronal functions. Until now, whether age-induced neuronal deficiency could be alleviated by engraftment of glial progenitor cell (GPC) derived astrocytes remained unknown. In the current study, GPCs were generated from embryonic cortical neural stem cells i...

Metabolic disorders induced by arsenic exposure have attracted great public concern. However, it remains unclear whether hypothalamus-based central regulation mechanisms are involved in this process. Here, we exposed mice to 100 μg/L arsenic in drinking water and established a chronic arsenic exposure model. Our study revealed that chronic arsenic...

Oral squamous cell carcinoma (OSCC) is the most common type of oral malignancy, and metastasis accounts for the poor prognosis of OSCC. Autophagy is considered to facilitate OSCC development by mitigating various cellular stresses; nevertheless, the mechanisms of autophagy in OSCC cell proliferation and metastasis remain unknown. In our study, high...

Cd exposure has been demonstrated to induce a variety of metabolic disorders accompanied with imbalance of glucose and lipid homeostasis. The metabolic toxicity of Cd exposure at metabolome-wide level remains elusive. In our study, we demonstrated that Cd exposure via drinking water increased blood glucose levels, decreased serum insulin levels, le...

In this paper, we proposed a model of how corporate acquisition influences industrial performance by exploring industry-level and firm-level ownership characteristics in emerging markets. Based on a database of 1,934 acquisitions of listed firms in China, we examined the relationship between corporate acquisition type and industrial performance and...

Cadmium (Cd) is a toxic heavy metal that can facilitate the development and progression of breast cancer (BC). Emerging evidence has indicated that the progression of Cd-exposed BC is related to the dysregulation of microRNAs (miRNAs). The purpose of our study was to investigate the expression pattern and underlying mechanisms of miR-374c-5p in Cd-...

Background: With the global popularity of communication devices such as mobile phones, there are increasing concerns regarding the effect of radiofrequency electromagnetic radiation (RF-EMR) on the brain, one of the most important organs sensitive to RF-EMR exposure at 1,800 MHz. However, the effects of RF-EMR exposure on neuronal cells are unclear...

Aging causes astrocyte morphological degeneration and functional deficiency, which impairs neuronal functions. Until now, whether age-induced neuronal deficiency could be alleviated by engraftment of glial progenitor cell (GPC) derived astrocytes remained unknown. In the current study, GPCs were generated from embryonic cortical neural stem cells i...

Cadmium (Cd) is a carcinogen that stimulates breast cancer (BC) progression. Rapamycin is a macrolide antibiotic produced by Streptomyces hygroscopicus that possesses a wide array of pharmacological activities, including anti-BC activity. However, the effects of rapamycin on Cd-increased BC progression and the underlying mechanism have not been ful...

Arsenic is one of the most common environmental pollutants. Neurotoxicity induced by arsenic has become a major public health concern. However, the effects of arsenic-induced neurotoxicity in the brain and the underlying molecular mechanisms are not well understood. N-acetyl-cysteine (NAC) is a thiol-based antioxidant that can antagonize heavy meta...

In an asymmetric international R&D alliance, a central research question is: how and when emerging market firms (EMFs) can acquire knowledge and foster their domestic innovation? To address this key question, we build on resource dependence theory (RDT) and particularly its core construct of mutual dependence (MD), and develop an MD model of R&D al...

Doxorubicin (DOX) is a widely used antitumor drug that causes severe cardiotoxicity in patients; no effective strategy yet exists to address this problem. We previously reported that 8-formylophiopogonanone B (8-FOB), a natural isoflavone in Ophiopogon japonicas, antagonizes paraquat-induced hepatotoxicity. Here, we explored the mechanisms underlyi...

Countries are often characterized with a diverse set of subcultures, exerting different impacts on innovation among different ethnic groups. This article comparatively analyzes how national culture, as measured by Hofstede's six cultural values, influences the entrepreneurial innovativeness (EI) of three Malaysian ethnic firms (Malaysian Chinese, I...

G9a, a histone methyltransferase, has been found to be upregulated in a range of tumor tissues, and contributes to tumor growth and metastasis. However, the impact of G9a inhibition as a potential therapeutic target in nasopharyngeal carcinoma (NPC) is unclear. In the present study we aimed to investigate the anti-proliferative effect of G9a inhibi...

The increasing intensity of environmental radiofrequency electromagnetic fields (RF-EMF) has increased public concern about its health effects. Of particular concern are the influences of RF-EMF exposure on the development of the brain. The mechanisms of how RF-EMF acts on the developing brain are not fully understood. Here, based on high-throughpu...

Bisphenol A (BPA) is a high-production-volume industrial chemical that facilitates the development of breast cancer. However, the molecular mechanism associated with BPA-induced breast cancer cell proliferation and migration remains elusive. In our study, we exposed MCF-7 cells to different concentrations of BPA (0.1, 1 and 10 μM) for 24, 48, or 72...

Nickel (Ni) is a heavy metal that is both an environmental pollutant and a threat to human health. However, the effects of Ni on the central nervous system in susceptible populations have not been well established. In the present study, the neurotoxicity of Ni and its underlying mechanism were investigated in vivo and in vitro. Ni exposure through...

Purpose Post-acquisition control is a crucial factor affecting acquisition performance. We investigate how post-acquisition control strategy affects cross-border acquisition performance of Chinese multinational enterprises (MNEs) through a configurational perspective. Design/methodology/approach Based on 70 cross-border acquisition cases by Chines...

Bisphenol A (BPA), an environmental endocrine-disrupting compound, has been revealed associated with metabolic disorders such as obesity, prediabetes, and type 2 diabetes (T2D). However, its underlying mechanisms are still not fully understood. Here, we provide new evidence that BPA is a risk factor for T2D from a case-control study. To explore the...

Cadmium (Cd), which is considered a carcinogenic metal, promotes breast cancer (BC) progression, but the precise mechanism remains unclear. Herein, MCF-7 and T47-D cells were treated with 0.1, 1, and 10 μM cadmium chloride (CdCl2) for 24, 48 and 72 h. In our study, Cd exposure significantly accelerated the proliferation, migration and invasion of M...

Purpose This paper compares four external technology acquisition channels' (foreign technology transfer, exporting, inter-industry R&D spillover and domestic technology transfer) contributions to Chinese high-tech enterprises' innovation in the moderating role of absorptive capacity (AC). Design/methodology/approach Using technological catch-up th...

The ecosystem perspective on innovation and business are becoming critical for organizational innovation, but there is a lack of theoretical consistency concerning the terminology of innovation ecosystem. To remedy this research gap, we introduce the innovation ecosystem in the international business (IB) context and enrich the research about innov...

Trimethyltin chloride (TMT) is widely used as a constituent of fungicides and plastic stabilizers in the industrial and agricultural fields, and is generally acknowledged to have potent neurotoxicity, especially in the hippocampus; however, the mechanism of induction of neurotoxicity by TMT remains elusive. Herein, we exposed Neuro-2a cells to diff...

Conceptualized as an escape response to the misalignment between firm needs and home country institutions, institutional escapism appears to be ignored in the research on emerging market firms (EMFs) and particularly small medium-sized enterprises (SMEs). As an integral part of institutional theory, however, the escape view could be especially appl...

The growth of outward foreign direct investment from emerging markets has led to increased scholarly attention on the internationalization of emerging market firms (EMFs). We break from the recent strategic approach on internationalizing EMFs to develop a problematization approach, which permits us to introduce a geographic relational perspective....

Introduction: Trimethyltin chloride (TMT) is a potent neurotoxin that causes neuroinflammation and neuronal cell death. Melatonin is a well-known anti-inflammatory agent with significant neuroprotective activity. Methods and results: Male C57BL/6J mice were intraperitoneally injected with a single dose of melatonin (10 mg/kg) before exposure to...

The formation of fat‐laden foam cells, which contributes to the fatty streaks in the plaques of atheromas, is an important process in atherosclerosis. Vascular smooth muscle cells (VSMCs) are a critical origin of foam cells. However, the mechanisms that underlie VSMC foam cell formation are not yet completely understood. Here, we demonstrated that...

China’s services sector mergers and acquisitions (M&As) in emerging economies, such as the Belt and Road Strip (BRS), have been increasing rapidly. Past studies have focused on M&A market value performance (MVP) in developed regions and industry sectors, ignoring M&As in emerging economies and services sectors. Drawing on signal theory effects of M...

Purpose The purpose of this paper is to examine the relationships between environment turbulence, knowledge transfer and innovation performance for emerging market multinationals (EMNEs) in an asymmetric international R&D alliance. Design/methodology/approach Data were collected through a survey of high-tech firms in Zhejiang Province of China fro...

Purpose This paper aims to investigate whether a complementary effect exists between government R&D subsidies (GRSs) and intellectual property rights (IPR) protection on innovation performance in the pharmaceutical manufacturing industry in China. This paper also attempts to understand whether this complementary effect is significantly different a...

Cadmium (Cd) is a toxic metal that is widely found in numerous environmental matrices and induces serious adverse effects in various organs and tissues. Bone tissue seems to be a crucial target of Cd contamination. Macroautophagy/autophagy has been proposed to play a pivotal role in Cd-mediated bone toxicity. However, the mechanisms that underlie C...

Taking an ecological perspective, we examine how two types of interdependence among business incubators located in the same region – mutualism and competition – affect the performance of these incubators. Using a dataset on Chinese National Technology Business Incubators (NTBIs) from 2008 to 2012, we show that incubator interdependence, measured by...

Despite the rise of interest in emerging market multinationals (EMNEs), the question of whether outward foreign direct investment (FDI) influences their resource acquisition in home countries remains underexplored. Contrary to the prior literature, which contends that EMNEs build outbound linkage through outward FDI so as to leverage outbound resou...

Despite the rise of interest in emerging market multinationals (EMNEs), the question of whether outward foreign direct investment (FDI) influences their resource acquisition in home countries remains underexplored. Contrary to the prior literature, which contends that EMNEs build outbound linkage through outward FDI so as to leverage outbound resou...

Based on the theory of complex adaptive system (CAS), we analyzed the complexity of regional innovation system (RIS). And then we established the AIITD evolutional model for revealing inherent law of RIS, which referred to agglomeration, networking, institutional thickness and degeneration. Subsequently we analyzed three mechanisms, resource alloca...

Purpose The purpose of this paper is to conduct a systematic literature review of the studies that have analyzed the impact of culture on innovation. Design/methodology/approach The authors carried out a systematic literature review of peer-reviewed articles in the past 37 years (January 1980-January 2017). Based on a total of 61 identified prim...

This paper focuses on the importance of dynamic capabilities in shaping the nature of international strategies of emerging market multinationals from mid-range economies. We argue that dynamic capabilities theory provides an insightful approach to understanding the internationalization of emerging market multinationals and their strategic choices....

Cracking the Western markets: International acquisitions by Chinese enterprises in advanced economies

With an increasing importance of outward foreign direct investment (OFDI) by multinationals (MNCs) from China in advanced economies, there is a need for deepening our knowledge of these Chinese MNCs not simply regarding their benefi ts and concerns, but more importantly regarding their dynamic and complex contexts. In this article, we investigate c...

Thyroid hormones play a crucial role in midbrain dopaminergic (DA) neuron development. However, the underlying molecular mechanisms remain largely unknown. In this study, we revealed that thyroid hormone treatment evokes significant calcium entry through canonical transient receptor potential (TRPC) channels in ventral midbrain neural stem cells an...

Toll-like receptor 4 (TLR4) plays critical roles in vascular inflammation, lipid accumulation and atherosclerosis development. However, the mechanisms underlying these processes are still not well established, especially in vascular smooth muscle cells (VSMCs). ATP-binding cassette transporter G1 (ABCG1) is one of the key genes mediating inflammati...

What drives the international expansion strategy of Chinese new ventures? By integrating the institution-based view and resource-based view of firm strategy, the authors propose that perceived institutional hardship has negative effects on internationalisation strategies of Chinese new ventures, while a firm’s dynamic capabilities (e.g. strategic f...

What drives the international expansion strategy of Chinese new ventures? By integrating the institution-based view and resource-based view of firm strategy, the authors propose that perceived institutional hardship has negative effects on internationalisation strategies of Chinese new ventures, while a firm's dynamic capabilities (e.g. strategic f...

Glial precursor transplantation provides a potential therapy for brain disorders. Before its clinical application, experimental evidence needs to indicate that engrafted glial cells are functionally incorporated into the existing circuits and become essential partners of neurons for executing fundamental brain functions. While previous experiments...

SIRT1 is a multifaceted NAD+-dependent protein deacetylase known to act as a tumor promoter or suppressor in different cancers. Here, we describe a novel mechanism of SIRT1-induced hepatocellular carcinoma (HCC) metastasis. SIRT1 overexpression was frequently detected in human HCC specimens and was associated with microvascular invasion (P = 0.0039...

Exposure to extremely low-frequency electromagnetic fields (ELF-EMFs) can enhance hippocampal neurogenesis in adult mice. However, little is focused on the effects of ELF-EMFs on embryonic neurogenesis. Here, we studied the potential effects of ELF-EMFs on embryonic neural stem cells (eNSCs). We exposed eNSCs to ELF-EMF (50 Hz, 1 mT) for 1, 2, and...

The knockdown efficiency of TRPC1-siRNA. The knockdown efficiency of TRPC1-siRNA. (A) The mRNA expression of TRPC1 after TRPC1-siRNA transfected for 3 days. n = 5, ** p < 0.01. (B, C) The protein expression of TRPC1. eNSCs were transfected with TRPC1-siRNA for 3 days. The protein expression of TRPC1 was detected at 1 day and 3 days after differenti...

Full length image of the blots of NeuroD, Ngn1, and TRPC1. Full length image of the blots of NeuroD, Ngn1, and TRPC1. (A) Full length image of the blots of NeuroD (The NeuroD antibody (sc-398891) is purchased from Santa Cruz Corp. The real position of NeuroD in the membrane showed small bias compared to its molecular weight (50 kDa). However, the p...

TRPC1-siRNA eliminates the effects of ELF-EMF on NeuroD and Ngn1 expression. TRPC1-siRNA eliminates the effects of ELF-EMF on NeuroD and Ngn1 expression. eNSCs were first transfected with TRPC1-siRNA or control-siRNA for 3 days to silence TRPC1 expression. Then the cells were cultured in differentiation medium and exposed to ELF-EMF for 3 days. (A)...

Tuj1 positive neuron expressed TRPC1. Tuj1 positive neuron expressed TRPC1. eNSCs were cultured in differentiation medium for 3 days. The cells were then fixed for Tuj1 and TRPC1 staining. Scale bar: 25 μm. (TIF)

High and fast response of H2S sensing at room temperature has been realized from NiO/ZnO hetetojunction nanowire (NW) arrays as a self-powered gas sensor. The piezoelectric output generated by NiO/ZnO NW nanogenerator (NG) can act as both the power source and sensing signal. Upon exposure to 1000 ppm H2S at room temperature, the piezo-voltage of Ni...

The activation of Toll-like receptor 4 (TLR4) signaling has an important role in promoting lipid accumulation and pro-inflammatory effects in vascular smooth muscle cells (VSMCs), which facilitate atherosclerosis development and progression. Previous studies have demonstrated that excess lipid accumulation in VSMCs is due to an inhibition of the ex...

Theoretically grounded in the ownership, location, and internalization (OLI) paradigm and institutional theory, this article investigates major macro-level factors that determine cross-border mergers and acquisitions (CBMAs) by Chinese firms in developed markets. Using panel data of Chinese CBMA deals in developed markets from 1996 to 2012, we foun...