Pierre-Marie David

Université de Montréal | UdeM · Faculté de Pharmacie

At the fringes of the unprecedented medication scale-up in the treatment of HIV, many African countries have experienced dramatic antiretroviral drug stock-outs. Usually considered the result of irrational decisions on behalf of local politicians, programme managers and even patients (who are stigmatised as immoral), these problems seem not to be s...

‘Preparing for the next epidemic’ has been a recurrent theme in global health in recent years. Starting with SARS, by way of the Avian influenza, and intensifying after the 2013–2016 Ebola outbreak, the urgency of preparing for the next health disaster has been recommended by numerous global health stakeholders. Recommendations and global partnersh...

Objectives The Central African Republic (CAR), a site of recurrent disease emergence, developed a noteworthy epidemiological surveillance system from the colonial period, but its health measures have remained among the world’s lowest. To understand this disparity between surveillance and public health, we examined selected moments in its history of...

Some observers have described the coronavirus pandemic as an ‘Anthropocene disease,’ thereby highlighting its connection with this new ecological era that is characterised by the considerable pressure human activities are exerting on ecosystems and the consequences on public health, society and the environment. This article focuses on the recent em...

Background Undervaccination is a public health issue that disproportionately affects underserved populations. Pharmacists are accessible health care professionals who have the potential to better reach communities. The aim of this study is to understand how organizational obstacles influence the pharmacist’s ability to meet underserved clients’ vac...

This paper presents an examination of the contrasting regulatory environments of Prescription Digital Therapeutics (PDTx) in the United States and South Korea. The contrasted contexts aim to illuminate the societal, political, and economic factors that have shaped these divergent paths and their consequences for the development and accessibility of...

Computer-aided detection algorithms based on artificial intelligence are increasingly being tested and used as a means for detecting tuberculosis in countries where the epidemic is still present. Computer-aided detection tools are often presented as a global solution that can be deployed in all the geographical areas concerned by tuberculosis, but...

Drug exceptional access programs (DEAPs) exist across Canada to address gaps in access to pharmaceuticals. These programs circumvent standard procedures, raising epistemic, economic, social and political issues. This commentary provides insights into these issues by revealing the context and procedures on which these programs depend.

Les logiciels de détection assistée par ordinateur basée sur l’intelligence artificielle (CAD-IA), combinés aux radiographies numériques du thorax, ont récemment été présentés comme une solution facile à un problème complexe : « mettre fin à la tuberculose d’ici 2030 ». L’Organisation mondiale de la santé (OMS) a recommandé l’utilisation de ces dis...

Context Social determinants of health are drivers of vaccine inequity and lead to higher risks of complications from infectious diseases in under vaccinated communities. In many countries, pharmacists have gained the rights to prescribe and administer vaccines, which contributes to improving vaccination rates. However, little is known on how they d...

Globally, the COVID-19 pandemic took a high toll on health human resources, especially in contexts where these resources were already fragile. In Quebec, to make up for the shortage of health human resources, and to contain the COVID-19 outbreaks in long-term care facilities, many hospital staff (including a majority of nurses) were sent to those f...

During the COVID-19 pandemic outbreak, COVID-19 healthcare-associated infections (HAI) and risk management became major challenges facing hospitals. Using evidence from a research project, this commentary presents: 1) various communication and information strategies implemented by four hospitals and their staff in Brazil, Canada and France to reduc...

In this concluding article of the special issue, we examine lessons learned from hospitals’ resilience to the COVID-19 pandemic in Brazil, Canada, France, Japan, and Mali. A quality lesson learned (QLL) results from a systematic process of collecting, compiling, and analyzing data derived ideally from sustained effort over the life of a research pr...

In response to the disruptions caused by COVID-19, hospitals around the world proactively or reactively developed and/or re-organized their governance structures to manage the COVID-19 response. Hospitals’ governance played a crucial role in their ability to reorganize and respond to the pressing needs of their staff. We discuss and compare six hos...

Computer Aided Detection software based on Artificial Intelligence (AI-CAD), combined with chest X-rays have recently been promoted as an easy fix for a complex problem: ending TB by 2030. WHO has recommended the use of such imaging devices in 2021 and many partnerships have helped propose benchmark analysis and technology comparisons to facilitate...

We provide an overview of the latest evidence on computer-aided detection (CAD) software for automated interpretation of chest radiographs (CXRs) for TB detection. CAD is a useful tool that can assist in rapid and consistent CXR interpretation for TB. CAD can achieve high sensitivity TB detection among people seeking care with symptoms of TB and in...

Among hospital responses to the COVID19 pandemic worldwide, service reorganization and staff reassignment have been some of the most prominent ways of adapting hospital work to the expected influx of patients. In this article, we examine work reorganization induced by the pandemic by identifying the operational strategies implemented by two hospita...

During the first and second waves of the pandemic, Quebec was among the Canadian provinces with the highest COVID-19 mortality rates. Facing particularly large COVID-19 outbreaks in its facilities, an integrated health and social services center in the province of Quebec (Canada), developed resilience strategies. To explore these diverse responses...

Context: Social determinants of health drivers of vaccine inequity and leading to higher risks of complication from infectious diseases in under vaccinated communities. In many countries, pharmacists have gained the rights to prescribe and administer vaccines, which contributes in improve vaccination rates. Little is however known on how they defin...

In recent years, there has been a swift rise in the development of digital therapies (DTx). As a result of various technological advances and accessibility to patients, it is now possible to develop and offer therapeutic interventions in a digital manner. These take the form of an evidence-based intervention that is administered in digital form to...

Resilience has accompanied the COVID-19 pandemic as a rallying motto, with calls by governments for a resilient society, resilient families and schools, and, of course, resilient healthcare systems in the face of this unprecedented pandemic shock. Resilience had already gained traction as an analytical concept in public health research for approxim...

Disclaimer In an effort to expedite the publication of articles related to the COVID-19 pandemic, AJHP is posting these manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final versi...

Background: Surgical antibiotic prophylaxis (SAP) has been proved to decrease the rate of surgical site infections (SSI), but compliance to SAP guidelines remains suboptimal. Aim: This study evaluated the impact of periodically sending individualized feedback letters to surgeons and anesthesiologists on their compliance rate to SAP guidelines....

Context: In Quebec, Bill 31, adopted on March 18, 2020, extended vaccination to pharmacists. Despite many advantages, this new practice comes with public health issues reinforced in the context of COVID-19. Therefore, it is essential to understand the opportunities and challenges of the participation of community pharmacists in influenza vaccinati...

Type 2 diabetes is a complex chronic disease that requires ongoing monitoring by an interprofessional team to prevent complications. The INMED (INterprofessional Management and Education in Diabetes) care pathway was developed by our team to optimize primary care services for these patients and their families. The objective of this study is to desc...

Commonly described as the passage from school to practice, transition to practice, as a concept, as yet to be explored in-depth, is clearly circumscribed and conceptualised to better address the issues experienced by new health professionals when they begin their professional practice. This study intends to describe how the process of transition to...

More than 40 years after the Alma-Ata Declaration on Primary Health Care, it is time to take stock. A look back at the evolution of pharmaceutical policies reveals the extent to which international health has transformed in the last four decades. The imperative of equitable access to healthcare, reaffirmed in Astana in 2018, has still not been achi...

Objectives This study aimed to identify factors contributing to pharmacists’ engagement in vaccination services during the first influenza vaccination campaign in 2019–2020 for the Canadian province of Quebec, led by community pharmacists. Methods A mixed-methods study was conducted using a sequential exploratory design. Semi-structured interviews...

Background Automated radiologic analysis using computer-aided detection software (CAD) could facilitate chest X-ray (CXR) use in tuberculosis diagnosis. There is little to no evidence on the accuracy of commercially-available deep learning-based CAD in different populations, including patients with smear-negative tuberculosis and people living with...

Introduction Agitation and violent behaviours are common conditions developed by patients with acute traumatic brain injury (TBI) in intensive care units (ICUs). Healthcare professionals caring for these patients have various tools to manage these behaviours, but lack of a formal protocol to assess and manage them makes caring for these patients a...

An amendment to this paper has been published and can be accessed via the original article.

Background All prevention efforts currently being implemented for COVID-19 are aimed at reducing the burden on strained health systems and human resources. There has been little research conducted to understand how SARS-CoV-2 has affected health care systems and professionals in terms of their work. Finding effective ways to share the knowledge and...

Background Little is known about volunteers from Northern research settings who participate in vaccine trials of highly infectious diseases with no approved treatments. This article explores the motivations of HIV immunocompromised study participants in Canada who volunteered in a Phase II clinical trial that evaluated the safety and immunogenicity...

Background: All prevention efforts currently being implemented for COVID-19 are aimed at reducing the burden on strained health systems and human resources. There has been little research conducted to understand how SARS-CoV-2 has affected healthcare systems and professionals in terms of their work. Finding effective ways to share the knowledge and...

The debate on herd immunity has strongly marked the political and scientific management of Sars-Cov2, as has been widely reported in the media. The language of immunity between gambling and speculation for a time, was tempered by oracles, when Imperial College models predicted the disaster in Britain. However, the wager on natural herd immunity did...

Rationale, aims and objectives Patients undergoing haemodialysis receive on average 10–17 medications, which increase the risk of falls, adverse drug reactions and hospitalizations. Supervised discontinuation of potentially inappropriate medications may lower these risks. Although many calls have been made for deprescribing in the haemodialysis set...

Methods Opioid misuse has reached epidemic status in many countries. This crisis—recognized since 2014—questions the practices of prescribing and dispensing. Did this public health issue change pharmaceutical practices? This literature review presents pharmaceutical practices regarding treatment of noncancer pain. We will assess whether these pract...

Les préoccupations relatives aux ruptures de stock en médicaments antirétroviraux et leurs conséquences en termes de résistances biologiques aux traitements contre le VIH sont passées relativement inaperçues jusqu'à récemment. En effet, ces problèmes, qui prennent depuis peu une place plus importante au sein de politiques de santé mondiale, ont été...

By describing the experience from dispensing antiretroviral drugs to asylum seekers infected with HIV in Montreal we argue for the relational dimensions of pharmaceutical care. Between 2010 and 2016, the Government of Canada changed the medical coverage for refugees and asylum seekers, leading to some uncertainty about what types of care were reimb...

Purpose Between 2012 and 2016, the Government of Canada modified health insurance for refugees and asylum seekers. In Quebec, this resulted in refusals of care and uncertainties about publicly reimbursed services, despite guaranteed coverage for people with this status under the provincial plan. The Chronic Viral Illness Service (CVIS) at the McGi...

New powerful drugs against hepatitis C can cure the disease, but they are not widely distributed because their exorbitant prices are destabilizing healthcare systems in both African and European countries. This article takes access to hepatitis C treatments since 2013 in France and in Cameroon as a lens to analyze the rationing of pharmaceutical tr...

Social sciences are important for training in pharmacy faculties. The course set up at the Faculty of Pharmacy of the University of Montreal in 2011 is a very innovative way to meet this challenge. The purpose of this report is to share this experience by providing a synthetic description. Many students were able to develop new skills and strengthe...

Teaching public health principles such as health promotion to healthcare professionals has gained attention in the last decade. The objective of this paper is to describe an innovative course that was developed in the Pharm.D programme in the Faculty of Pharmacy at the Université de Montréal with a focus on health promotion through community-based...

This article was migrated. The article was not marked as recommended. This article aims at describing and analysing the way in which pharmacy students work together in the context of an innovative course on community health. The article uses content analysis of two focus groups held in 2015 with 14 students from the Faculty of Pharmacy at the Unive...

Le « commun » et la nécessité de le penser ou le repenser résonnent aujourd’hui comme un important défi lancé à la sociologie. Tant idéologiquement que matériellement, la globalisation amène une reconfiguration des vies individuelles et collectives aux quatre coins du globe et nous confronte à une crise d’ampleur mondiale inédite, de nature à la fo...

To give the measure a meaning, it should be reported to a system of values, which permits evaluation and judgment. This is the theoretical bias that underlies this article on writing practices in the fight against AIDS from an approach at the intersection of the political anthropology of health and science studies. To investigate the pathways and p...

Measurement under the measure The scriptural economy of AIDS and its treatment in the Central African Republic (CAR) To give the measure a meaning, it should be reported to a system of values, which permits evaluation and judgment. This is the theoretical bias that underlies this article on writing practices in the fight against AIDS from an appro...

Suicide rates are high in high-income countries like Canada and the United States, where 10 to 12 people per 100 000 commit suicide every year. In the United States, in 2011 there were 73.3 emergency room visits per 100 000 people for suicide attempts with prescription drugs. The latter were also involved in 13% of completed suicides between 1999 a...

Fragile states have been raising increasing concern among donors since the mid-2000s. The policies of the Global Fund to fight HIV/AIDS, Malaria, and Tuberculosis (GF) have not excluded fragile states, and this source has provided financing for these countries according to standardized procedures. They represent interesting cases for exploring the...

Over the past 40 years, beginning with the seminal work of medical sociologists like Erving Zola and Peter Conrad, thousands of studies have contributed to describing and analyzing medicalization. What is common to most of these studies is that pharmaceutical drugs are almost always involved in the process described. Since medications and their omn...

La santé occupe aujourd’hui une place centrale dans les problématiques de développement international. Cette place paraît toutefois ambiguë dans les discours et politiques publiques de développement : présentée à la fois comme fin mais aussi comme moyen du développement. Réinterroger les notions de santé et de développement dans leur historicité no...

Pharmaceutical practice in France is evolving as presented in the legislation reforming hospitals and regarding patients, health and the territories. Hence, the pharmaceutical “territory” has been reconfigured and requires evolving ideas about pharmaceutical training. At the heart of this paper is the following question: What can social sciences br...

Pharmaceutical practice in France is evolving as presented in the legislation reforming hospitals and regarding patients, health and the territories. Hence, the pharmaceutical "territory" has been reconfigured and requires evolving ideas about pharmaceutical training. At the heart of this paper is the following question: What can social sciences br...

Recurrent ideological discourses on hospital are significative of what is expected from it and even further than its therapeutical fonction: its very symbolic fonctions for society. Nominative registered delivery of drugs in the care units by pharmaceutical assistants is a specific organisation of hospital work. The aim of this paper is to assess w...