Pi Guo

Pi Guo
Shantou University | STU · Department of Preventive Medicine

Ph.D

About

117
Publications
17,809
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
2,042
Citations
Additional affiliations
November 2018 - November 2018
Shantou University
Position
  • Professor (Associate)
Education
September 2013 - May 2015
Sun Yat-Sen University
Field of study
  • Biostatistics
September 2010 - July 2013
Shantou University
Field of study
  • Biostatistics and epidemiology
September 2006 - July 2010
Southern Medical University
Field of study
  • Statistics

Publications

Publications (117)
Article
In epidemiological studies, it is important to identify independent associations between collective exposures and a health outcome. The current stepwise selection technique ignores stochastic errors and suffers from a lack of stability. The alternative LASSO-penalized regression model can be applied to detect significant predictors from a pool of c...
Article
Full-text available
Purpose Early-stage hepatocellular carcinoma (E-HCC) is being diagnosed increasingly, and in one half of diagnosed patients, recurrence will develop. Thus, it is urgent to identify recurrence-related markers. We investigated the effectiveness of CpG methylation in predicting recurrence for patients with E-HCCs. Patients and Methods In total, 576 p...
Article
Background: In China, dengue remains an important public health issue with expanded areas and increased incidence recently. Accurate and timely forecasts of dengue incidence in China are still lacking. We aimed to use the state-of-the-art machine learning algorithms to develop an accurate predictive model of dengue. Methodology/principal findings...
Article
Full-text available
Backgrounds: Evidence is scarce on the relation between maternal exposure to ambient air pollution during pregnancy and fetal growth in developing countries. Moreover, the current evidence is inconsistent. We aimed to investigate the association of trimester-specific exposure to air pollution with risk of being born small for gestational age (SGA)...
Article
Full-text available
As a common vector-borne disease, dengue fever remains challenging to predict due to large variations in epidemic size across seasons driven by a number of factors including population susceptibility, mosquito density, meteorological conditions, geographical factors, and human mobility. An ensemble forecast system for dengue fever is first proposed...
Article
Full-text available
Introduction: Paternal smoking associated with childhood overweight and obesity has been a concern, but studies have not investigated smoking exposure and smoking details. We investigated the association of exposures from paternal smoking as well as smoking details on offspring overweight/obesity. Methods: A total of 4513 children (aged 7-8 year...
Article
Full-text available
Importance: Many studies have reported an association of interpregnancy interval (IPI) between 2 consecutive births with adverse birth outcomes in low- and middle-income countries. However, most of these studies ignore the implications of some unmeasured confounders. Objective: To explore the association of IPI with adverse perinatal outcomes....
Article
Full-text available
Background Congenital heart defects are the most common type of birth defects and bring a heavy disease burden in China. Examining the temporal and spatial trends of congenital heart defects epidemics can give some elementary knowledge for succeeding studies.Objective To characterize the spatial-temporal patterns of the prevalence of congenital hea...
Article
Full-text available
Background: To validate a competency-based assessment scale for students majoring in clinical medicine, ASK-SEAT. Students' competency growth across grade years was also examined for trends and gaps. Methods: Questionnaires were distributed online from May through August in 2018 to Year-2 to Year-6 students who majored in clinical medicine at th...
Article
Full-text available
Microplastic pollution is an emerging environmental problem, and little research has focused on its impact on the human body. Based on retrospective case series, the study required participants to fill out a questionnaire and provide sputum samples in order to investigate the presence of microplastics in human sputum and determine whether humans in...
Article
Full-text available
Some epidemiological studies have confirmed the association between environmental factors and congenital heart defects (CHD). While the possibility that maternal ambient heat exposures are related to CHD has received little attention. Our study aims to investigate the association between maternal ambient extreme heat exposure early in pregnancy and...
Article
Full-text available
We aimed to estimate the non-accidental and cause-specific mortality burden attributed to diurnal temperature range (DTR) and the relative contributions of low, high, and extremely low and extremely high DTR in Yunnan, southwest China. Furthermore, we explored the possible effect modification of the DTR–mortality association by season, sex, age, et...
Article
Full-text available
Objectives This study aimed to investigate the temporal and spatial characteristics of cleft lip and/or palate based on a large-scale birth defect monitoring database. Methods Data on perinatal infants and children with cleft lip and/or palate defects from 1 January 2015 to 31 December 2018 in Guangdong province of China were collected. The variab...
Article
Full-text available
Antiretroviral treatment (ART) and pre-exposure prophylaxis (PrEP) for HIV-serodiscordant couples, effectively reduce mortality, transmission events and influence quality of life at the expense of increased costs. We aimed to evaluate health economics of antiretroviral-based strategies for HIV-serodiscordant couples in the China context. A determin...
Article
Full-text available
Ambient PM2.5 (particulate matter ≤ 2.5 μm in aerodynamic diameter) constituents have been related to mean changes in semen quality, but focusing on the mean response may not well capture distributional and heterogeneous effects of PM2.5 constituents on semen quality. In this study, 2314 semen samples of 622 men between Jan 1, 2019 and Dec 31, 2019...
Article
Backgrounds Evidence for the effects of temperature variability on risk of congenital anomalies is lacking. We aimed to examine the association of temperature variability during fetal organogenesis period (weeks 3-8 post-conception) with major congenital anomalies. Methods A retrospective cohort study comprising 4,787,356 singleton live-births and...
Preprint
Full-text available
As a common vector-borne disease, dengue fever still remains a lot of challenges to forecast for which the significant distinction of epidemic scale is affected by multiple factors, such as mosquito density, meteorological conditions, geographical environment, travel and so on. To track down the epidemic scale and forecast the remaining time of epi...
Article
Full-text available
Objective: It is unclear whether uterine fibroids are associated with the occurrence of hypertensive disorders of pregnancy (HDP). Thus, this study aimed to evaluate the association between uterine fibroids and HDP in a prospective cohort. Methods: Overall, 2404 pregnant women who received antenatal care were enrolled in a prospective cohort in...
Article
Full-text available
IntroductionObservational studies have shown that tea consumption has a potentially beneficial effect on bone health. However, few studies have assessed the effects of types of tea consumed on bone health. We aimed to investigate whether drinking oolong tea is associated with increased calcaneus bone mineral density (BMD) in postmenopausal women.Me...
Article
Full-text available
At present, there is still a lack of studies to address the dynamics underlying epidemics of bacillary dysentery (BD), with particular concern on the role of climatic drivers across different regions of a country or the world. The variability of climate domains, non-linear interactions, and covariations of climatic variables pose challenges for exp...
Article
Full-text available
The magnitudes of toxicities and effects of the ambient concentration of total mass (weight) of particulate matter with aerodynamic diameter less than 2.5 μm (PM2.5) on adverse health outcomes manifest regional- and temporal-specific heterogeneity due to the variability of embedded chemical components. To explore acute hazards of 39 chemical compon...
Article
Full-text available
Background It is still unclear about the association between ambient air pollution and attack risk of acute myocardial infarction (AMI) in South China. This study assessed the effects of short-term exposure to ambient air pollutants on hospital admission of AMI in Guangzhou, South China. Materials and methods We obtained the information on 19,622...
Article
We aimed to explore whether there were cold and heat temperature adverse effects on years of life lost (YLL) for non-accidental mortality in Yuxi, a southwest plateau region of China. From data for 89,467 non-accidental deaths over an 8-year study period, we used a general linear regression model combined with a distributed lag non-linear model to...
Article
Full-text available
The social contact patterns associated with the infectious disease transmitted by airborne droplets or close contact follow specific rules. Understanding these processes can improve the accuracy of disease transmission models, permitting their integration into model simulations. In this study, we performed a large-scale population-based survey to c...
Article
Full-text available
Objectives Adverse birth outcomes pose a great threat to the public health and bring a heavy burden of disease in China. A comprehensive examination of the temporal and spatial trends of preterm birth (PTB), low birth weight (LBW) and small for gestational age (SGA) epidemics can provide some elementary information for subsequent aetiological and e...
Article
Full-text available
Background: Ovarian cancer (OC) is the seventh most common malignancy worldwide and the most lethal gynaecological malignancy. We aimed to explore global geographical patterns and temporal trends from 1973 to 2015 for 41 countries in OC incidence and especially to analyse the birth cohort effect to gain further insight into the underlying causal f...
Article
Full-text available
Hepatitis B surface antigen (HBsAg) seroclearance during treatment is associated with a better prognosis among patients with chronic hepatitis B (CHB). Significant gaps remain in our understanding on how to predict HBsAg seroclearance accurately and efficiently based on obtainable clinical information. This study aimed to identify the optimal model...
Article
Introduction: Chronic kidney disease (CKD) has been associated with incident atrial fibrillation (AF) and its complications, but data from Asian cohorts are limited. Aim: To explore the relationship of AF recurrence after catheter ablation (CA) with eGFR as a continuous variable, and with different renal function categories (normal: estimated gl...
Article
Full-text available
Objective Dengue is a mosquito-transmitted virus infection that remains rampant across the tropical and subtropical areas worldwide. However, the spatial and temporal dynamics of dengue transmission are poorly understood in Chao-Shan area, one of the most densely populated regions on China’s southeastern coast, limiting disease control efforts. We...
Article
Full-text available
Objectives There are country and regional variations in the prevalence of hyperuricaemia (HUA). The prevalence of HUA and non-valvular atrial fibrillation (NVAF) in southern China is unknown. Design A cross-sectional study. Setting and participants A total of 11 488 permanent residents aged 35 or older from urban and rural areas of Guangzhou, Chi...
Article
Background: Studies regarding blood pressure of Nepal have demonstrated a contrasting prevalence. We aimed at providing a generalized estimate of the prevalence of hypertension and prehypertension in urban, suburban, and rural areas of Nepal. Methods: This systematic review followed PRISMA guidelines. A thorough search of PubMed, EMBASE, and Web...
Article
Background: Female sex has been linked with worse prognosis in patients with atrial fibrillation (AF). Clinical risk stratification of women with AF may help decision-making before catheter ablation (CA). Aim: To evaluate arrhythmia outcomes and the predictive value of clinical scores for arrhythmia recurrence in a large cohort of Chinese patients...
Article
Background: At present, there are few studies on the effect of short-term interactions between ambient air pollutants and temperature on cause-specific emergency department visits in China. This study aimed to explore their short-term interactions on cause-specific emergency department visits using data collected from a total of 65 public hospitals...
Article
The association between maternal exposure to gaseous air pollutants and preterm birth is still unclear. We assessed the effects of ambient sulfur dioxide (SO 2 ), nitrogen dioxide (NO 2 ), and carbon monoxide (CO) on preterm birth based on a large cohort of live births in China. Data for a total of 1,098,600 singleton live births in nine subtropica...
Article
Full-text available
Objective To examine the total non-accidental mortality burden attributable to ambient temperatures and assess the effect modification of the burden by specific causes of death and individual characteristics in a high plateau area in southwest China. Methods Using daily mortality and meteorological data from 2009 to 2016, we applied a quasi-Poisso...
Article
Full-text available
Abstract Precise prevalence of atrial fibrillation (AF) and the associated risk factors in southern China are rarely reported. This large population-based follow-up study, the Guangzhou Heart Study, was conducted from 2015 to 2017 to fill up this gap. Permanent residents aged 35 years and above in Guangzhou city were enrolled and demographic factor...
Article
Full-text available
Objectives: We aim to provide a global geographical picture of pancreatic cancer incidence and temporal trends from 1973 to 2015 for 41 countries. Methods: Joinpoint regression and age-period-cohort model was used. Results: In 2012, the highest age-adjusted rate was in Central and Eastern Europe for males and North America for females. Most re...
Article
Background: China experienced an unprecedented outbreak of dengue in 2014, and the number of dengue cases reached the highest level over the past 25 years. There is a significant delay in the release of official case count data, and our ability to timely track the timing and magnitude of local outbreaks of dengue remains limited. Material and metho...
Article
Full-text available
Background: Obesity or overweight is related to worse outcomes in patients with atrial fibrillation (AF) following catheter ablation (CA). The role of being underweight in relation to recurrent arrhythmias post AF ablation is less certain. We conducted a retrospective study to investigate the association of body mass index (BMI) with arrhythmia ou...
Article
Full-text available
Background Biomarkers have been related to the arrhythmia recurrence following catheter ablation (CA) of atrial fibrillation (AF). We hypothesized that concurrent measurement of several biomarkers would additively improve their predictive value. Methods One thousand four hundred and ten consecutive AF patients (68% male; 57.2 ± 11.6 years) undergo...
Article
Full-text available
Patients with hepatocellular carcinoma (HCC) always require routine surveillance and repeated treatment, which leads to accumulation of huge amount of clinical data. A predictive model utilizes the time-series data to facilitate dynamic prognosis prediction and treatment planning is warranted. Here we introduced an analytical approach, which conver...
Article
Preoperative lymph node (LN) status is important for the treatment of bladder cancer (BCa). Here, we report a genomic-clinicopathologic nomogram for preoperatively predicting LN metastasis in BCa. In the discovery stage, 325 BCa patients from TCGA were involved and LN-status-related mRNAs were selected. In the training stage, multivariate logistic...
Data
Baidu search query data extraction, and search keyword selection and search index construction. (DOCX)
Data
Time series of weekly dengue cases, dengue search index (DSI), mean temperature, mean rainfall and mean relative humidity in the cities of Chaozhou and Heyuan, Guangdong province during the study period of 2011–2014. (TIF)
Data
Residuals analysis using an autocorrelation function (ACF) and a partial autocorrelation function (PACF) for the 1-week-ahead predictions of 2014 from support vector regression (SVR) models. (A) ACF analysis of the 1-week-ahead predictions in Guangzhou. (B) PACF analysis of the 1-week-ahead predictions in Guangzhou. (C) ACF analysis of the 1-week-a...
Data
Dynamic 1-week-ahead forecasts of dengue incidence of 2014 in the city of Zhongshan, Guangdong. (MP4)
Data
Time series of weekly dengue cases, dengue search index (DSI), mean temperature, mean rainfall and mean relative humidity in the cities of Guangzhou and Foshan, Guangdong province during the study period of 2011–2014. (TIF)
Data
Time series of weekly dengue cases, dengue search index (DSI), mean temperature, mean rainfall and mean relative humidity in the cities of Zhanjiang and Shanwei, Guangdong province during the study period of 2011–2014. (TIF)
Data
Time series of weekly dengue cases, dengue search index (DSI), mean temperature, mean rainfall and mean relative humidity in the cities of Shantou and Jieyang, Guangdong province during the study period of 2011–2014. (TIF)
Data
Observations and model predictions of dengue case counts in Zhongshan city, China, 2014. (A) Model forecasts using the SVR algorithm for the dengue epidemic period between the 41st to 53rd weeks (the last 12 weeks) in 2014. The black lines represent observed values, the blue dash lines denote model-based fitted values, the red dash lines correspond...
Data
Dynamic 1-week-ahead forecasts of dengue incidence of 2014 in the city of Guangzhou, Guangdong. (MP4)
Data
Dynamic 1-week-ahead forecasts of dengue incidence of 2014 in the city of Zhuhai, Guangdong. (MP4)
Data
Dynamic 1-week-ahead forecasts of dengue incidence of 2014 in the city of Shenzhen, Guangdong. (MP4)
Data
Five provinces at high risk of dengue infection in mainland China. (A) Geographic location of the provinces of Guangdong, Yunnan, Guangxi, Hunan, Fujian and Zhejiang. (B) Pie charts showing the percentage of the total number of dengue cases occurred in the country during the study period of 2011–2014 among the selected provinces. (TIF)