Philippe Goldin

Philippe Goldin
University of California, Davis | UCD · UC Davis Medical Center

PhD Psychology

About

127
Publications
119,240
Reads
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10,117
Citations
Introduction
Philippe Goldin currently works at the UC Davis Medical Center, University of California, Davis. Philippe does research in Neuroscience, Health Psychology and Behavioral Science.
Additional affiliations
March 2014 - June 2017
University of California, Davis
Position
  • Professor (Associate)
Education
July 2001 - June 2002
University of California, San Diego
Field of study
  • clinical psychology
August 1999 - June 2002
Veterans Administration San Diego Healthcare System & UC San Diego School of Medicine, Department of Psychiatry
Field of study
  • Psychology & Neuroscience
September 1995 - June 2002
Rutgers, The State University of New Jersey
Field of study
  • clinical psychology

Publications

Publications (127)
Article
Objective: This study examined the temporal dynamics of anxiety and depressive symptoms during a 12-week therapist-supported, smartphone-delivered digital health intervention for symptoms of depression and anxiety. Methods: A total of 290 participants were included in the present analyses (age Mean = 39.64, SD = 10.25 years; 79% female; 54% self...
Preprint
Objective: This study examined treatment outcomes (depression and anxiety symptoms) up to 24 months after the Meru Health Program (MHP), a 12-week licensed therapist-supported digital mental health intervention (DMHI).Methods: Data from 413 participants who participated in the intervention from February 6, 2017 to March 25, 2019 were used to test t...
Article
Full-text available
Meditation training is proposed to enhance mental well-being by modulating neural activity, particularly alpha and theta brain oscillations , and autonomic activity. Although such enhancement also depends on the quality of meditation, little is known about how these neural and physiological changes relate to meditation quality. One model characteri...
Article
Full-text available
As clinicians we have numerous tools at our disposal when working with patients in the therapeutic context, ranging from rapport building to empirically validated psychotherapy manuals. Psychoeducation is another invaluable clinical tool that can help patients make sense of the causes and consequences of their symptoms and how psychotherapy tools w...
Preprint
Full-text available
Background: The use of mindfulness in the treatment of anxiety and depression is becoming more and more widespread, but there are few reports that it has fundamentally changed patients' sense of life. Case Presentation: This report showed 9 year’s progress of treatment for Social Anxiety Disorder and Persistent Depressive Disorder in a 41year-old f...
Article
Social anxiety disorder (SAD) is characterized by negative self-referential processing, which triggers excessive emotional reactivity. In healthy individuals, positive self-views typically predominate and are supported by regions of the default mode network (DMN) that represent self-related information and regions of the frontoparietal control netw...
Article
Full-text available
Importance: Cognitive behavioral group therapy (CBGT) and mindfulness-based stress reduction (MBSR) are thought to help patients with social anxiety disorder (SAD) via distinct emotion-regulation mechanisms. However, no study has compared the effects of CBGT and MBSR on brain and negative emotion indicators of cognitive reappraisal and acceptance...
Article
Do people who have low-quality sleep tend to have more negative affect? This question is of great public interest, and many would assume the answer is “yes.” However, previous findings have been mixed, possibly due to differing measures of sleep and affect, or to a failure to separately examine negative affect reactivity and regulation. Across two...
Article
Social anxiety disorder (SAD) is characterized by negative self-beliefs and altered brain activation in the default-mode network (DMN). However, the extent to which there is neurocognitive heterogeneity in SAD remains unclear. We had two independent samples of patients perform a self-referential encoding task and complete self-reports of childhood...
Article
Full-text available
Predictive brain markers promise a number of important scientific, clinical, and societal applications. Over 600 predictive brain markers have been described in published reports, but very few have been tested in independent replication attempts. Here, we conducted an independent replication of a previously published marker predicting treatment res...
Article
Ambiguous sensory stimuli provide insight into the dynamics of the human mind. When viewing substantially different images in the two eyes (i.e., binocular rivalry (BR)), perception spontaneously fluctuates between the two images along with patch‐like mixtures of the two, with limited ability to control such fluctuations. Previous studies have show...
Article
Background : Cognitive-behavioral therapy and mindfulness-based stress reduction (MBSR) are two prominent evidence-based treatments for social anxiety disorder (SAD). It is not clear, however, whether outcomes of these two treatments are moderated by similar factors. For example, whereas anger suppression and anger expression each predict outcomes...
Article
Introduction Individuals with social anxiety disorder (SAD) are at elevated risk of loneliness, yet little research has examined loneliness in this population. Cognitive-behavioral group therapy (CBGT) and mindfulness-based stress reduction (MBSR) have demonstrated efficacy in treating SAD, yet research has not examined whether they lead to reducti...
Chapter
The goal of this chapter is to illustrate how neuroscience principles and brain circuitry can inform case formulation and communication between clinicians and patients. We provide rationale for incorporating neuroscience into clinical practice, describe brain networks relevant to psychopathology followed by how they may contribute to relevant sympt...
Preprint
UNSTRUCTURED Background: Anxiety and depression symptoms are highly correlated in adults with depression; however, little is known about their interaction and temporal dynamics of change during treatment. Thus, the primary aim of this study was to examine the temporal dynamics of anxiety and depressive symptoms during a 12-week therapist-supported,...
Preprint
Social anxiety disorder (SAD) is characterized by negative self-beliefs and altered brain activation in the default mode network (DMN). However, the extent to which there is neurocognitive heterogeneity in SAD remains unclear. We had two independent samples of patients perform a self-referential encoding task, and complete self-reports of childhood...
Article
Full-text available
Contemplative practices are thought to modify one’s experience of self and fundamentally change self-referential processing. However, few studies have examined the brain correlates of self-referential processing in long-term meditators. Here, we used the self-referential encoding task (SRET) to examine event-related potentials (ERP) during assessme...
Article
Full-text available
There is increasing interest in third-wave interventions that incorporate contemplative practices. Mindfulness and compassion meditation training programs have shown great promise. In the spirit of precision health, a refined understanding of participant features that identify who will and will not benefit from specific types of contemplative train...
Preprint
Full-text available
Objective: The aim was to examine change in burnout and depressive symptoms among physicians enrolled in an evidence-based digital health intervention, the Meru Health Program (MHP). Methods: We recruited 27 physicians with evidence of work-related stress as reported from a single-item burnout measure from the Palo Alto Foundation Medical Group and...
Article
Full-text available
Background: Loneliness is a universal experience that is particularly relevant to social anxiety. However, research has not examined loneliness among treatment-seeking individuals with social anxiety disorder (SAD) or assessed whether mal-adaptive or adaptive emotion regulation strategies moderate the relationship between social anxiety and lonelin...
Article
A b s t r a c t: Major depressive disorder (MDD) is a prevalent and highly debilitating psychiatric condition that affects many young adults worldwide. This brief review summarizes the current available data about the use of ketamine as a treatment for MDD. We describe pharmacological mechanisms, dose considerations, drug interactions, side effect...
Article
Full-text available
Background: Social anxiety disorder (SAD) is characterized by negative self-beliefs (NSBs) that are thought to maintain symptom severity-at least in part-by impairing emotion regulation. Few studies to date have investigated the neural basis of emotion regulation during NSBs in SAD. Moreover, different regulation strategies have not been directly...
Article
Objective: Sudden gains (SGs) have been found to occur during randomized controlled trials (RCTs) for social anxiety disorder (SAD). Evidence is mixed whether SGs relate to treatment outcome in SAD. We examined SGs in two RCTs for SAD. Method: Study 1 (N = 68) examined SGs in individual cognitive-behavioral therapy (CBT), and Study 2 (N = 100) c...
Article
One of the core features of social anxiety disorder (SAD) is the persistent fear of being evaluated. Fear of evaluation includes fear of negative evaluation (FNE) and fear of positive evaluation (FPE). Few studies have examined the relationship between self-reported FNE and FPE and neural responses to simulated negative and positive social evaluati...
Article
Background and Objectives: Poor sleep is prevalent among individuals with social anxiety disorder (SAD) and may affect treatment outcome. We examined whether: (1) individuals with SAD differed from healthy controls (HCs) in sleep quality, (2) baseline sleep quality moderated the effects of treatment (Cognitive–behavioral group therapy [CBGT] vs. mi...
Article
Social anxiety disorder (SAD) has been shown to be associated with difficulty in the ability to vicariously share others' positive emotions (positive affective empathy). Mixed evidence also suggests potentially impaired recognition of the positive and negative emotions of others (cognitive empathy) and impaired or enhanced sharing of the negative e...
Article
Gaze avoidance is an important feature of social anxiety disorder (SAD) and may serve as a biobehavioral marker of SAD. The purpose of the present study was to replicate and extend findings on gaze avoidance in SAD via eye tracking during a computerized social simulation. Patients with SAD (n = 27) and a (sub)sample of demographically-matched healt...
Preprint
BACKGROUND Depression is one of the most common mental health disorders and severely impacts physical, psychological and social functioning. To address access barriers to care, we developed Ascend - a smartphone-delivered, therapist-supported, 8-week intervention based on several evidence-based psychological treatments for depression and anxiety....
Article
Full-text available
Background Depression is one of the most common mental health disorders and severely impacts one’s physical, psychological, and social functioning. To address access barriers to care, we developed Ascend—a smartphone-delivered, therapist-supported, 8-week intervention based on several evidence-based psychological treatments for depression and anxie...
Preprint
Depression is common and severely impacts physical, psychological and social functioning. To address access barriers to care, we developed Ascend - a smartphone-delivered, therapist-supported, 8-week intervention based on several evidence-based psychological treatments for depression and anxiety. We examined whether the previously-reported, end-of-...
Article
Self-referential processing is critical to understanding social anxiety disorder (SAD). This study examined neural differences in self-referential processing in healthy controls (HC) and participants with SAD at pre- and post-treatment. Participants (n = 64) underwent fMRI scanning while viewing a video of themselves (“Self”) or another person (“Ot...
Preprint
Contemplative practices are thought to modify one's experience of self and fundamentally change self-referential processing. However, few studies have examined the effect of long-term meditation training on brain correlates of self-referential processing. Here we used the self-referential encoding task (SRET) to examine event-related potentials (ER...
Article
Full-text available
Background: Depression is a very common condition that impairs functioning and is often untreated. More than 60% of the treatments for depressive disorder are administered in primary care settings by care providers who lack the time and expertise to treat depression. To address this issue, we developed Ascend, a therapist-supported, mobile phone-de...
Article
Full-text available
Emotion regulation (ER) is an important skill for well-being. Cognitive reappraisal is a goal-oriented cognitive change strategy. Acceptance involves decentering from immediate habits of reactivity, observing moment-to-moment shifts in thoughts, emotions, and sensations. These two regulation strategies are thought to have different effects on emoti...
Article
Full-text available
Common factors are understood to play an important role in many therapeutic interventions. What is not yet clear is whether the relative importance of common factors in therapeutic interventions varies as a function of treatment type and/or disorder. In this study, we were specifically interested in the common factor of working alliance. We randomi...
Article
Objective: Network analysis allows us to identify the most interconnected (i.e., central) symptoms, and multiple authors have suggested that these symptoms might be important treatment targets. This is because change in central symptoms (relative to others) should have greater impact on change in all other symptoms. It has been argued that network...
Article
Emotion regulation is thought to involve communication between and within large-scale brain networks that underlie emotion reactivity and cognitive control. Aberrant network interaction might therefore be a key neural feature of mental disorders that involve emotion dysregulation. Here we tested whether connectivity hierarchies within and between e...
Preprint
Full-text available
BACKGROUND Depression is a very common condition that impairs functioning and is often untreated. More than 60% of the treatments for depressive disorder are administered in primary care settings by care providers who lack the time and expertise to treat depression. To address this issue, we developed Ascend, a therapist-supported, mobile phone–del...
Article
Background Depression is a very common condition that impairs functioning and is often untreated. More than 60% of the treatments for depressive disorder are administered in primary care settings by care providers who lack the time and expertise to treat depression. To address this issue, we developed Ascend, a therapist-supported, mobile phone–del...
Preprint
Objective: Network analysis allows us to identify the most interconnected (i.e., central) symptoms, and multiple authors have suggested that these symptoms might be important treatment targets. This is because change in central symptoms (relative to others) should have greater impact on change in all other symptoms. It has been argued that networks...
Article
Full-text available
Objective: Meditation is one type of mental training that has been shown to produce many cognitive benefits. Meditation practice is associated with improvement in concentration and reduction of stress, depression, and anxiety symptoms. Furthermore, different forms of meditation training are now being used as interventions for a variety of psycholog...
Article
We examined (1) differences between controls and patients with social anxiety disorder (SAD) in emotional clarity and attention to emotions; (2) changes in emotional clarity and attention to emotions associated with cognitive-behavioral group therapy (CBGT), mindfulness-based stress reduction (MBSR), or a waitlist (WL) condition; and (3) whether em...
Article
Full-text available
A growing literature has begun to document the effects of compassion training on a variety of important interpersonal behaviors (e.g., helping behavior). What is not yet well understood, however, is what impact compassion training has on affect and affect regulation. To examine this issue, we implemented a 9-week compassion training program in whic...
Article
Full-text available
Background and objective The Mindfulness to Meaning Theory (MMT) provides a detailed process model of mindful positive emotion regulation. Design We conducted a post-hoc reanalysis of longitudinal data (N = 107) derived from a RCT of mindfulness-based stress reduction (MBSR) versus cognitive-behavioral therapy (CBT) for social anxiety disorder to...
Chapter
Full-text available
Compassion is a powerful feature of human experience and is a key component of individual, interpersonal, organizational and societal well-being. It is a fundamental skill that can be trained. Cultivating compassion may contribute to sustained well-being in individuals, groups, and organizations. There is now a growing scientific and clinical inter...
Preprint
Objective: To investigate treatment outcome and mediators of Cognitive-Behavioral Group Therapy (CBGT) vs. Mindfulness-Based Stress Reduction (MBSR) vs. Waitlist (WL) in patients with generalized social anxiety disorder (SAD). Method: 108 unmedicated patients (55.6% female; mean age = 32.7, SD = 8.0; 43.5% Caucasian, 39% Asian, 9.3% Hispanic, 8.3%...
Preprint
Contemporary scholarship on mindfulness casts it as a form of purely nonevaluative engagement with experience. Yet, traditionally mindfulness was not intended to operate in a vacuum of dispassionate observation, but was seen as facilitative of eudaimonic mental states. In spite of this historical context, modern psychological research has neglected...
Article
Full-text available
Cognitive distortions are thought to be central to the development and maintenance of anxiety disorders and are a widely acknowledged treatment target in cognitive-behavioral interventions. However, little research has focused on the measurement of cognitive distortions. The Cognitive Distortions Questionnaire (CD-Quest; de Oliveira, Trial-based co...
Article
Full-text available
We examined whether cognitive-behavioral therapy (CBT) would influence the relationship between two distinct forms of emotion regulation (cognitive reappraisal and expressive suppression) and satisfaction with life in patients with social anxiety disorder (SAD). When compared to healthy adults (n = 42) at baseline (Study 1), patients with SAD (n =...
Article
Full-text available
This study examines the impact of Cognitive-Behavioral Group Therapy (CBGT) versus Mindfulness-Based Stress Reduction (MBSR) versus Waitlist (WL) on self-views in patients with social anxiety disorder (SAD). One hundred eight unmedicated patients with SAD were randomly assigned to 12 weeks of CBGT, MBSR, or WL, and completed a self-referential enco...
Article
Background: Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of ac...
Article
Objective: The goal of this study was to investigate treatment outcome and mediators of cognitive-behavioral group therapy (CBGT) versus mindfulness-based stress reduction (MBSR) versus waitlist (WL) in patients with generalized social anxiety disorder (SAD). Method: One hundred eight unmedicated patients (55.6% female; mean age = 32.7 years, SD...
Article
Emotion dysregulation is a core feature of bipolar disorder (BD) that persists into periods of remission. Neuroimaging studies show aberrant neural responses during emotion regulation (ER) in patients with BD relative to healthy controls, but behavioural evidence for ER deficits is sparse and conflicting. This study aimed to explore ER in BD using...
Chapter
Full-text available
The human mind is one of the most intriguing complex systems found in nature. Research has been conducted to develop a computer model of the mind from the Theravada Buddhist description detailed in the Abhidhamma literature. Within this context, the mind is identified as a conditional flow of thoughts that is characterized by 52 mental factors, suc...
Article
Full-text available
Contemporary scholarship on mindfulness casts it as a form of purely nonevaluative engagement with experience. Yet, traditionally mindfulness was not intended to operate in a vacuum of dispassionate observation, but was seen as facilitative of eudaimonic mental states. In spite of this historical context, modern psychological research has neglected...
Article
Full-text available
The human mind is one of the most intriguing complex systems found in nature. Research has been conducted to develop a computer model of the mind from the Theravada Buddhist description detailed in the Abhidhamma literature. Within this context, the mind is identified as a conditional flow of thoughts that is characterized by 52 mental factors, suc...
Article
Background and objectives: Difficulties with attentional control have long been thought to play a key role in anxiety and depressive disorders. However, the nature and extent of attentional control difficulties in social anxiety disorder (SAD) are not yet well understood. The current study was designed to assess whether attentional control for non...
Article
Full-text available
Mind wandering, or the tendency for attention to drift to task-irrelevant thoughts, has been associated with worse intra- and inter-personal functioning. Utilizing daily experience sampling with 51 adults during 9-weeks of a compassion meditation program, we examined effects on mind wandering (to neutral, pleasant, and unpleasant topics) and caring...
Article
Background: Women have more angina, but less obstructive coronary artery disease (CAD), than men. Vascular function abnormalities, such as endothelial and microvascular dysfunction, are commonly found in these women, but treatment strategies are incomplete. We investigated whether mindfulness-based stress reduction (MBSR) would result in reduced an...
Article
Full-text available
We examined whether social anxiety severity at pre-treatment would moderate the impact of mindfulness-based stress reduction (MBSR) or aerobic exercise (AE) for generalized social anxiety disorder. MBSR and AE produced equivalent reductions in weekly social anxiety symptoms. Improvements were moderated by pre-treatment social anxiety severity. Mind...
Article
Many psychiatric disorders involve problematic patterns of emotional reactivity and regulation. In this review, we consider recent findings regarding emotion and emotion regulation in the context of social anxiety disorder (SAD). We first describe key features of SAD which suggest altered emotional and self-related processing difficulties. Next, we...
Article
Full-text available
Individuals with social anxiety disorder (SAD) suffer from intense fear of social evaluation, heightened emotional reactivity to social cues, and problems implementing effective forms of emotion regulation (ER), particularly in social situations. In this chapter, we examine the role of emotion and ER in SAD to elucidate how different families of ER...