Petra S Hüppi

Petra S Hüppi
University of Geneva | UNIGE · Departement of Pediatrics

MD Professor of Pediatrics&newborn medicine

About

14
Publications
4,689
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263
Citations

Publications

Publications (14)
Article
Full-text available
Background and purpose: Currently available MRI scoring systems of cerebral maturation in term and preterm infant at term equivalent age do not include the changes of transient fetal compartments that persist to term age. We studied the visibility and the pattern of these structures in healthy term newborns compared to preterm infants at term equi...
Article
Full-text available
Human and animal models suggest that maternal hormonal and physiological adaptations during pregnancy shape maternal brain functioning and behavior crucial for offspring care and survival. Less sensitive maternal behavior, often associated with psychobiological dysregulation and the offspring's behavioral and emotional disorders, has been observed...
Chapter
Neurodevelopmental follow-up is a critical component of the evaluation of the neurological development and ongoing clinical needs of the high-risk newborn. Such follow-up is important because it has become increasingly clear that a substantial number of infants who exhibit neurological abnormalities in the newborn period will experience later neuro...
Poster
Full-text available
The goal of our study was to: (i) asses regional cortical differences in vascular architectonics, and (ii) to identify spatio-temporal differences in gene networks relevant for angiogenesis in the developing human neocortex.
Article
Importance Very preterm infants are at risk of developing encephalopathy of prematurity and long-term neurodevelopmental delay. Erythropoietin treatment is neuroprotective in animal experimental and human clinical studies. Objective To determine whether prophylactic early high-dose recombinant human erythropoietin (rhEPO) in preterm infants improve...
Article
Full-text available
Lactoferrin (Lf) is a sialic acid (Sia)-rich, iron-binding milk glycoprotein that has multifunctional health benefits. Its potential role in neurodevelopment and cognition remains unknown. To test the hypothesis that Lf may function to improve neurodevelopment and cognition, the diet of postnatal piglets was supplemented with Lf from days 3 to 38....
Article
Full-text available
ABSTRACT: Introduction A significant proportion of prematurely born children encounter behavioral difficulties, such as attention deficit or hyperactivity, which could be due to executive function disorders. Aims To examine whether the standard neurodevelopmental assessment offered to premature children in Switzerland recognizes executive function...
Article
Magnetic resonance imaging (MRI) is a safe and high-resolution neuroimaging modality that is increasingly used in the neonatal population to assess brain injury and its consequences on brain development. It is superior to cranial ultrasound for the definition of patterns of both white and gray matter maturation and injury and therefore has the pote...
Article
Modification of early brain development is at the basis of neurologic, neuropsychiatric and behavioral disorders in children and adults. With the advances in reproductive medicine and neonatal intensive care, we are confronted with an increasing number of high-risk newborns that are exposed to various exogenous influences at an early point of brain...
Article
With the advances in reproductive medicine and neonatal intensive care we are confronted with an incrasing number of high-risk wewborns, who suffer from considerable neurologic morbidity that often is associated with lifelong handicaps. New diagnostic tools are therefore needed to assess brain development, detect early brain injury, and monitor int...

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