Peter M. A. Sloot

Peter M. A. Sloot
University of Amsterdam | UVA · Department of Computational Science

Prof. Dr.

About

716
Publications
74,547
Reads
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8,856
Citations
Introduction
http://www.peter-sloot.com/ I try to understand how nature processes information. I study this 'natural information processing' in complex systems by computational modeling and simulation as well as through formal methods. My work is applied to a large variety of applications with a focus on -but not limited to- Biomedicine.
Additional affiliations
April 2014 - present
Nanyang Technological University
Position
  • Professor (Full)
Description
  • Scientific co-director of the Complexity Institute at NTU
January 2014 - present
Nanyang Technological University
Position
  • Managing Director
Description
  • A new research institute on Complexity and Complex Systems. I co-direct this with Prof. Steve Lansing
October 2010 - present
ITMO University
Position
  • Professor (Full)
Description
  • I started my Leading Scientist Mega Grant research here in October 2014

Publications

Publications (716)
Article
Healthcare is undergoing a profound technological and digital transformation and has become increasingly complex. It is important for burns professionals and researchers to adapt to these developments which may require new ways of thinking and subsequent new strategies. As Einstein has put it: ‘We must learn to see the world anew'. The relatively n...
Article
Full-text available
The outbreak of the COVID-19 pandemic has led to an upsurge of protests. The emergence of civil resistance movements is often associated with various conditions of social systems. The analysis of social systems also shows the importance of considering the behaviour time scale and in particular slow-fast dynamics. The fine-grained datasets of the su...
Article
Full-text available
Due to phenomena such as urban heat islands, outdoor thermal comfort of the cities’ residents emerges as a growing concern. A major challenge for mega-cities in changing climate is the design of urban spaces that ensure and promote pedestrian thermal comfort. Understanding pedestrian behavioural adaptation to urban thermal environments is criticall...
Article
Insurgency conflicts pose significant challenges to societies globally. The increase of insurgency conflicts creates a need to understand how insurgencies arise, and to identify societal drivers of insurgencies or effective strategies to counter them. In this paper, we analyze the contributions of computational modeling methods for the analysis of...
Article
One of the most central questions in network science is: which nodes are most important? Often this question is answered using structural properties such as high connectedness or centrality in the network. However, static structural connectedness does not necessarily translate to dynamical importance. To demonstrate this, we simulate the kinetic Is...
Article
Addiction is a complex biopsychosocial phenomenon, impacted by biological predispositions, psychological processes, and the social environment. Using mathematical and computational models that allow for surrogative reasoning may be a promising avenue for gaining a deeper understanding of this complex behavior. This paper reviews and classifies a se...
Article
Full-text available
Chronic stress contributes to the onset of type 2 diabetes (T2D), yet the underlying etiological mechanisms are not fully understood. Responses to stress are influenced by earlier experiences, sex, emotions and cognition, and involve a complex network of neurotransmitters and hormones, that affect multiple biological systems. In addition, the syste...
Article
The Kumbh Mela festival is the largest mass gathering in the world that is celebrated every three years. In 2016, it attracted over 70 million people to Ujjain, India. The Mahakal temple is the “heart” of the festival that attracts a huge number of pilgrims and needs to accommodate with massive crowds. These types of events pose significant safety...
Article
Full-text available
Cross-sectional studies are widely prevalent since they are more feasible to conduct compared with longitudinal studies. However, cross-sectional data lack the temporal information required to study the evolution of the underlying dynamics. This temporal information is essential to develop predictive computational models, which is the first step to...
Article
Full-text available
Urbanisation and common mental disorders (CMDs; ie, depressive, anxiety, and substance use disorders) are increasing worldwide. In this Review, we discuss how urbanicity and risk of CMDs relate to each other and call for a complexity science approach to advance understanding of this interrelationship. We did an ecological analysis using data on urb...
Preprint
Full-text available
The outbreak of the COVID-19 pandemic has led to a resurgence of protests. Various societal conditions of social systems, such as economic stability, demographic ageing, and political elites, are often associated to the emergence of civil resistance movements. Several qualitative and quantitative models have been developed to analyse the relationsh...
Article
Full-text available
Public health is threatened by climate change and extreme temperature events worldwide. Differences in health predispositions, access to cooling infrastructure and occupation raises an issue of heat-related health inequality in those vulnerable and disadvantaged demographic groups. To address these issues, a comprehensive understanding of the effec...
Article
Full-text available
Pedestrian movements during large crowded events naturally consist of different modes of movement behaviour. Despite its importance for understanding crowd dynamics, intermittent movement behaviour is an aspect missing in the existing crowd behaviour literature. Here we analyse movement data generated from nearly 600 Wi-Fi sensors during large ente...
Article
Full-text available
Production networks are integral to economic dynamics, yet dis-aggregated network data on inter-firm trade is rarely collected and often proprietary. Here we situate company-level production networks within a wider space of networks that are different in nature, but similar in local connectivity structure. Through this lens, we study a regional and...
Chapter
Information exists when it is being copied—a rather important notion—think of bits, DNA and lottery. This concept is highlighted by Shannon’s classical paper on Information theory which describes a mathematical theory of communication, communication being equal to the copying of information. The second leading notion is that the copying process onl...
Preprint
Full-text available
Production networks are integral to economic dynamics, yet dis-aggregated network data on inter-firm trade is rarely collected and often proprietary. Here we situate company-level production networks among networks from other domains according to their local connectivity structure. Through this lens, we study a regional and a national network of in...
Preprint
Addiction is a complex biopsychosocial phenomenon, impacted by biological predispositions, psychological processes, and the social environment. Using mathematical and computational models that are capable of surrogative rea- soning may be a promising avenue for gaining a deeper understanding of this complex behavior. This paper reviews formal model...
Preprint
Full-text available
Cross-sectional studies are widely prevalent since they are more feasible to conduct compared to longitudinal studies. However, cross-sectional data lack the temporal information required to study the evolution of the underlying processes. Nevertheless, this is essential to develop predictive computational models which is the first step towards cau...
Article
Full-text available
There has been a number of reports showing evidence that human movement behaviour follows patterns resembling Lévy walks. These studies focus on the foraging patterns of rural humans and human hunter-gatherers. Here, we investigate motion patterns of visitors of a large dance event in the Johan Cruijff ArenA football stadium in Amsterdam. We find i...
Book
The six-volume set LNCS 12742, 12743, 12744, 12745, 12746, and 12747 constitutes the proceedings of the 21st International Conference on Computational Science, ICCS 2021, held in Krakow, Poland, in June 2021.* The total of 260 full papers and 57 short papers presented in this book set were carefully reviewed and selected from 635 submissions. 48 fu...
Book
The six-volume set LNCS 12742, 12743, 12744, 12745, 12746, and 12747 constitutes the proceedings of the 21st International Conference on Computational Science, ICCS 2021, held in Krakow, Poland, in June 2021.* The total of 260 full papers and 57 short papers presented in this book set were carefully reviewed and selected from 635 submissions. 48 fu...
Book
The six-volume set LNCS 12742, 12743, 12744, 12745, 12746, and 12747 constitutes the proceedings of the 21st International Conference on Computational Science, ICCS 2021, held in Krakow, Poland, in June 2021.* The total of 260 full papers and 57 short papers presented in this book set were carefully reviewed and selected from 635 submissions. 48 fu...
Book
The six-volume set LNCS 12742, 12743, 12744, 12745, 12746, and 12747 constitutes the proceedings of the 21st International Conference on Computational Science, ICCS 2021, held in Krakow, Poland, in June 2021.* The total of 260 full papers and 57 short papers presented in this book set were carefully reviewed and selected from 635 submissions. 48 fu...
Book
The six-volume set LNCS 12742, 12743, 12744, 12745, 12746, and 12747 constitutes the proceedings of the 21st International Conference on Computational Science, ICCS 2021, held in Krakow, Poland, in June 2021.* The total of 260 full papers and 57 short papers presented in this book set were carefully reviewed and selected from 635 submissions. 48 fu...
Book
The six-volume set LNCS 12742, 12743, 12744, 12745, 12746, and 12747 constitutes the proceedings of the 21st International Conference on Computational Science, ICCS 2021, held in Krakow, Poland, in June 2021.* The total of 260 full papers and 57 short papers presented in this book set were carefully reviewed and selected from 635 submissions. 48 fu...
Article
Full-text available
Background The mechanisms of action and efficacy of cisplatin and paclitaxel at cell population level are well studied and documented, however the localized spatio-temporal effects of the drugs are less well understood. We explore the emergence of spatially preferential drug efficacy resulting from variations in mechanisms of cell-drug interactions...
Article
Full-text available
This research proposes a system based on a combination of various components for parallel modelling and forecasting the processes in networks with data assimilation from the real network. The main novelty of this work consists of the assimilation of data for forecasting the processes in social networks which allows improving the quality of the fore...
Chapter
Full-text available
Coronary artery bypass grafting with cardiopulmonary bypass activates the human innate immune system (HIIS) and invokes a vigorous inflammatory response that is systemic. This massive inflammatory reaction can contribute to the development of postoperative complications that could topple the state of the system from health to disease, or even to so...
Article
Full-text available
The analysis of questionnaires often involves representing the high-dimensional responses in a low-dimensional space (e.g., PCA, MCA, or t-SNE). However questionnaire data often contains categorical variables and common statistical model assumptions rarely hold. Here we present a non-parametric approach based on Fisher Information which obtains a l...
Article
Full-text available
The mechanisms and impact of bacterial quorum sensing (QS) for the coordination of population level behaviors are well studied under laboratory conditions. However, it is unclear how, in otherwise open environmental systems, QS signals accumulate to sufficient concentration to induce QS phenotypes, especially when quorum quenching (QQ) organisms ar...
Article
Full-text available
Group‐level obesity can be seen as an emergent property of a complex system, consisting of feedback loops between individual body weight perception, individual weight‐related behaviour and group‐level social norms (a product of group‐level ‘normal' body mass index (BMI) and sociocultural ‘ideal' BMI). As overweight becomes normal, the norm might be...
Article
Full-text available
Elevated walking speed is an indicator of increased pace of life in cities, caused by environmental pressures inherent to urban environments, which lead to short- and long-term consequences for health and well-being. In this paper we investigate the effect of walking speed on heat stress. We define the heat-stress-optimal walking speed and estimate...
Book
The seven-volume set LNCS 12137, 12138, 12139, 12140, 12141, 12142, and 12143 constitutes the proceedings of the 20th International Conference on Computational Science, ICCS 2020, held in Amsterdam, The Netherlands, in June 2020.* The total of 101 papers and 248 workshop papers presented in this book set were carefully reviewed and selected from 71...
Book
The seven-volume set LNCS 12137, 12138, 12139, 12140, 12141, 12142, and 12143 constitutes the proceedings of the 20th International Conference on Computational Science, ICCS 2020, held in Amsterdam, The Netherlands, in June 2020.* The total of 101 papers and 248 workshop papers presented in this book set were carefully reviewed and selected from 71...
Book
The seven-volume set LNCS 12137, 12138, 12139, 12140, 12141, 12142, and 12143 constitutes the proceedings of the 20th International Conference on Computational Science, ICCS 2020, held in Amsterdam, The Netherlands, in June 2020.* The total of 101 papers and 248 workshop papers presented in this book set were carefully reviewed and selected from 71...
Book
The seven-volume set LNCS 12137, 12138, 12139, 12140, 12141, 12142, and 12143 constitutes the proceedings of the 20th International Conference on Computational Science, ICCS 2020, held in Amsterdam, The Netherlands, in June 2020.* The total of 101 papers and 248 workshop papers presented in this book set were carefully reviewed and selected from 71...
Book
The seven-volume set LNCS 12137, 12138, 12139, 12140, 12141, 12142, and 12143 constitutes the proceedings of the 20th International Conference on Computational Science, ICCS 2020, held in Amsterdam, The Netherlands, in June 2020.* The total of 101 papers and 248 workshop papers presented in this book set were carefully reviewed and selected from 71...
Book
The seven-volume set LNCS 12137, 12138, 12139, 12140, 12141, 12142, and 12143 constitutes the proceedings of the 20th International Conference on Computational Science, ICCS 2020, held in Amsterdam, The Netherlands, in June 2020.* The total of 101 papers and 248 workshop papers presented in this book set were carefully reviewed and selected from 71...
Book
The seven-volume set LNCS 12137, 12138, 12139, 12140, 12141, 12142, and 12143 constitutes the proceedings of the 20th International Conference on Computational Science, ICCS 2020, held in Amsterdam, The Netherlands, in June 2020.* The total of 101 papers and 248 workshop papers presented in this book set were carefully reviewed and selected from 71...
Article
Full-text available
Background: The efficacy of smartphone apps for improving medication adherence in type 2 diabetes is not well studied in Asian populations. Objective: This study aimed to determine the feasibility, acceptability, and clinical outcomes of using a smartphone app to improve medication adherence in a multiethnic Asian population with type 2 diabetes...
Article
Morphological changes in bacterial biofilm structures arise from the fluid-structure interactions between the biofilm and the surrounding fluid. Depending on the magnitude of the force acting on the structure, the bacteria rearrange to attain an equilibrium shape or get washed away by the moving fluid. Understanding the dynamics behind the evolutio...
Article
Complexity of patient care is rapidly increasing as a consequence of rising numbers of patients with complex multimorbidity. Not just the patient as a whole, but also the networks of organs, tissues and cells are forming a complex adaptive system (CAS). A CAS is defined as a network of several components ('agents') with lots of mutual feedback loop...
Article
Full-text available
Background: Smartphone apps are becoming increasingly popular for supporting diabetes self-management. A key aspect of diabetes self-management is appropriate medication-taking. This study aims to systematically assess and characterise the medication management features in diabetes self-management apps and their congruence with best-practice evide...
Book
The International Conference on Computational Science is an annual conference that brings together researchers and scientists from mathematics and computer science as basic computing disciplines, as well as researchers from various application areas who are pioneering computational methods in sciences such as physics, chemistry, life sciences, engi...
Book
The five-volume set LNCS 11536, 11537, 11538, 11539 and 11540 constitutes the proceedings of the 19th International Conference on Computational Science, ICCS 2019, held in Faro, Portugal, in June 2019. The total of 65 full papers and 168 workshop papers presented in this book set were carefully reviewed and selected from 573 submissions (228 submis...
Article
Full-text available
Background Major alteration in lifestyle of human population has promoted Type 2 diabetes mellitus (T2DM) to the level of an epidemic. This metabolic disorder is characterized by insulin resistance and pancreatic β-cell dysfunction and apoptosis, triggered by endoplasmic reticulum (ER) stress, oxidative stress and cytokines. Computational modeling...
Book
The five-volume set LNCS 11536, 11537, 11538, 11539 and 11540 constitutes the proceedings of the 19th International Conference on Computational Science, ICCS 2019, held in Faro, Portugal, in June 2019. The total of 65 full papers and 168 workshop papers presented in this book set were carefully reviewed and selected from 573 submissions (228 submis...
Article
Full-text available
Alkaline phosphatase (AP) is an enzyme that exhibits anti-inflammatory effects by dephosphorylating inflammation triggering moieties (ITMs) like bacterial lipopolysaccharides and extracellular nucleotides. AP administration aims to prevent and treat peri- and post-surgical ischemia reperfusion injury in cardiothoracic surgery patients. Recent studi...
Preprint
Full-text available
Background: HIV treatment prescription is a complex process; clinical decision support systems (CDSS) can assist clinicians to choose optimal treatments. These support systems are based on clinical trials and expert knowledge; however, the amount of data available to these systems is limited. For this reason, CDSSs could be significantly improved b...
Article
Full-text available
It is still unclear under which conditions temporary combined antiretroviral therapy (cART) results in a prolonged remission after interruption. Clinical trials have contradicting reposts about the effect of cART during primary HIV infection on the disease progression. Here we propose that the apparent contradiction is due the presence of a window...
Article
Full-text available
Thermal comfort of people in outdoor urban spaces is a growing concern in cities due to climate change and urbanization. In outdoor settings the climate and behavior of people are more dynamic than in indoor situations, therefore a steady state of the thermoregulatory system is rarely reached. Understanding the dynamics of outdoor thermal comfort r...
Chapter
Malaria remains a deadly disease that affected millions of people in 2016. Among the five Plasmodium (P.) parasites which contribute to malaria diseases in humans. P. falciparum is a lethal one which is responsible for the majority of the world-wide-malaria-related deaths. Since the banana-shaped stage V gametocytes play a crucial role in disease t...
Chapter
Modelling and simulation of bacterial biofilms is a computationally expensive process necessitating use of parallel computing. Fluid dynamics and advection-consumption models can be decoupled and solved to handle the fluid-solute-bacterial interactions. Data exchange between the two processes add up to the communication overheads. The heterogenous...
Article
Full-text available
We perform the analysis of scientific collaboration at the level of universities. The scope of this study is to answer two fundamental questions: (i) can one indicate a category (i.e., a scientific discipline) that has the greatest impact on the rank of the university and (ii) do the best universities collaborate with the best ones only? Using two...