Peter J Horvath

University at Buffalo, The State University of New York | SUNY Buffalo · Department of Exercise and Nutrition Sciences

Background: During competition season, races and games can be scheduled multiple times a week or even within 24 hours. This may interfere with macronutrient periodization, carbohydrate loading regimen, hydration status and nutrition. Most of the studies investigating the influence of diet on performance do not take into consideration that an athle...

Background: In persons with multiple sclerosis (MS), the effect of nutrition on exercise performance and fatigue remains unknown. The objective was to determine whether a 3-day diet high in triglycerides (FAT) compared with a 3-day diet high in carbohydrates (CARB) would improve fatigue and exercise performance in persons with MS. Methods: A random...

Background. During competition season, races and games can be scheduled multiple times a week or even within 24 hours. This may interfere with macronutrient periodization, carbohydrate loading regimen, hydration status and nutrition. Most of the studies investigating the influence of diet on performance do not take into consideration that an athlet...

Background: Sarcopenia, a reduction in muscle mass and function seen in aging populations, may be countered by improving systemic carnosine stores via beta-Alanine (β-alanine) supplementation. Increasing systemic carnosine levels may result in enhanced anti-oxidant, neuro-protective and pH buffering capabilities. This enhancement should result in...

Background: We sought to assess the associations between nutrition and ambulation, daily activity, quality of life (QOL), and fatigue in individuals with mild-to-moderate disability with multiple sclerosis (MS). Methods: This cross-sectional pilot study included 20 ambulatory adult volunteers with MS (14 women and 6 men; mean ± SD age, 57.9 ± 10...

Introduction: Care providers consistently report negative consequences to their mental health as a direct result of their caregiving responsibilities. Specifically, they describe higher levels of distress, mental health problems, and depressive symptoms compared to their non-caregiving matched controls. Powerful Tools for Caregivers (PTC) is a nati...

Clinical issues associated with keeping giant anteaters (Myrmecophaga tridactyla) in captivity may be linked with colon health and digestive function. Chronic loose stools are one such problem often suspected to be related to dietary intake. The objective of this study was to determine the acceptability, digestibility and faecal composition in a po...

Background: D-aspartic acid may enhance athletic performance by regulating the hypothalamus-pituitary-gonadal axis to increase plasma testosterone. Increasing testosterone via D-aspartic acid, may lead to improved muscle function and concurrent improvements in athletic performance.

Objective: Contradictory data between the Insulin-Like Growth Factor System (IGF) system and exercise may be due to alteration in IGF binding proteins. Vitamin D (D) deficiency has been related to muscle weakness and Insulin Like Growth Factor Binding Protein 3 (IGFBP3). A Vit. D and acute exercise merge is proposed to modify the IGF system. Desi...

Background: Recent research has demonstrated improvements in cognitive function during bouts of high-intensity endurance exercise. Caffeine, the most commonly used ergogenic aid in the world, can improve cognition both at rest and during exercise and can also improve exercise performance during simulated cycling races. Purpose: To determine if caff...

This study assessed multiple salivary and plasma markers before and after incremental short-term maximal aerobic exercise and in a non-exercising control in conjunction with cognitive testing. Subjects: Apparently healthy 18-30 years old low CVD risk females participated (n = 19). Methods: Subjects completed two conditions: 1) exercise: short maxim...

The objective of the study was to examine salivary biomarker response to fluid consumption in exercising athletes. Exercise induces stress on the body and salivary alpha amylase (sAA) and salivary cortisol are useful biomarkers for activity in the sympathoadrenal medullary system and the hypothalamic pituitary adrenal axis which are involved in the...

The Effect of Pre Exercise Carbohydrate Consumption on Cognitive Function Glucose supplementation before exercise has been shown to improve exogenous glucose availability which may alter cognitive function. We tested the consumption of two carbohydrate containing drinks, Performance Drink® (PD) and Gatorade® (GA) prior to exercise to determine if...

Exercise is associated with elevated mood states and arousal. Observational studies support the claim that exercise can help individuals think more "clearly' with reports of improved mood and feelings of psychological well-being following exercise. However, laboratory studies have produced equivocal results. The purpose of this study is to examine...

Overexertion caused by increased pitch counts can evoke protective biomechanical responses signified by decreased ball velocity, such as reduced throwing arm kinematics and kinetics. Among skilled pitchers, overexertion may not always present ball velocity decrements, as compensatory throwing biomechanics aid in maintaining peak ball velocity while...

e20540 Background: Physical activity (PA) in prostate cancer (PC) survivors improves general QOL and fatigue, but the relationship between PA and genitourinary symptoms in PC survivors is unknown. The incidence of sexual dysfunction may be as high as 68% during active surveillance and 78% in men receiving conventional therapies. PA has mitigated er...

Dietary lignans may affect breast cancer by modifying tumor characteristics likely to affect prognosis. We investigated usual dietary intakes of total and specific lignans with tumor characteristics in 683 women with breast cancer and 611 healthy women without breast cancer enrolled in the Data Bank and BioRepository at Roswell Park Cancer Institut...

Malnutrition is prevalent among patients within certain cancer types. There is lack of universal standard of care for nutrition screening and a lack of agreement on an operational definition and on validity of malnutrition indicators. In a secondary data analysis, we investigated prevalence of malnutrition diagnosis with 3 classification methods us...

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s: AACR International Conference on Frontiers in Cancer Prevention Research‐‐ Nov 7-10, 2010; Philadelphia, PA Introduction: Although soy isoflavones intakes have been associated with reduced breast cancer risk in many populations, there is still uncertainty as to the relationships between these compounds and breast cancer clinical characteristics...

Studies examining the effect of soy protein on cardiovascular disease (CVD) risk factors have not taken advantage of the postprandial state as an adjunct to the fasting lipid profile. The American Heart Association has acknowledged the efficacy of soy protein in reducing CVD risk factors to be limited. We hypothesized that the postprandial state wo...

Two studies determined whether interval exercise reduces children's stress reactivity. For Experiment 1 children completed interval exercise (n=14) or watched TV (n=14) for 25 min. After 20 min rest children completed a speech task. Speech-induced diastolic blood pressure (DBP) reactivity was dampened in the exercise group (p<.05). For Experiment 2...

Most individuals at risk for developing cardiovascular disease (CVD) can reduce risk factors through diet and exercise before resorting to drug treatment. The effect of a combination of resistance training with vegetable-based (soy) versus animal-based (whey) protein supplementation on CVD risk reduction has received little study. The study's purpo...

This study examined whether (1) short-term maximal aerobic exercise to exhaustion affects Simple Reaction Time, Visual Spatial Memory, Continual Processing (attention), Code Substitution (short-term memory), and Working Memory over time and between groups and (2) exercise intensity and chronic aerobic activity in young healthy women affect cognitiv...

The traditional lipid profile compared with nuclear magnetic resonance (NMR) may underestimate the risk for cardiovascular disease and may explain some of the discrepancies in results between studies analyzing the salubrious effects of soy. Our purpose was to compare the traditional lipid profile with NMR quantification of the number of lipoprotein...

Sitting on a therapy ball or standing may be a passive means of increasing energy expenditure throughout the workday. The purpose of this study was to determine the energy expenditure and liking of performing clerical work in various postures. Subjects included 24 men and women employed in sedentary clerical occupations. Energy expenditure was meas...

Our purpose was to determine the relationship between energy intake, energy availability, dietary fat and lower extremity injury in adult female runners. We hypothesized that runners who develop overuse running-related injuries have lower energy intakes, lower energy availability and lower fat intake compared to non-injured runners. Eighty-six fema...

Only 30% to 50% of people produce the daidzein-metabolite equol after eating soy. We conducted a cross-sectional study of the associations between equol status, intake of soy foods, and mammographic density in a sample of postmenopausal women recruited at a radiology clinic near Buffalo, New York. Participants were 48 to 82 years old, had no histor...

Osteoporosis is a serious public health concern. Understanding the extent to which a bone density assessment affects change in dietary intake in postmenopausal women is needed. This study investigated whether results of bone density screening tests resulted in reported initiation or change in either dietary and/or supplemental calcium intake. Betwe...

Background: Most individuals at risk for developing cardiovascular disease (CVD) can reduce risk factors through diet and exercise before resorting to drug treatment. The effect of a combination of resistance training with vegetable-based (soy) versus animal-based (whey) protein supplementation on CVD risk reduction has received little study. The s...

This research examined how ground reaction forces (GRF) changed with fatigue induced by an exhaustive treadmill run in female runners. A separate retrospective and prospective analysis correlated initial magnitude of GRF and fatigue-induced changes in GRF with lower-extremity injury. Ninety adult female runners had vertical GRF measured before and...

The desired level of dietary fat intake is controversial. The effect of decreasing fat intake to 19% and increasing it to 50% from a control diet of 30% on nutritional status and cardiovascular risk factors in healthy individuals was studied. Eleven healthy subjects (5 men and 6 women) were randomized to consume diets with 19% and 50% calories from...

During inspiration, recruitment of the intrinsic laryngeal muscles (ILM) reduces the inspiratory load on the ventilatory pump muscles. The purpose of our study was to determine 1) whether the diaphragm adapts to denervation of the ILM, and 2) whether the additional stimulus of exercise training affects the degree to which the diaphragm adapts to IL...

The role of lipids on the immune responses to exercise has been under appreciated. This is due in large part to the relatively recent advances in immunology. In addition, the “fat phobia” in athletes, particularly female athletes, and their advisers has resulted in an over-emphasis on the role of carbohydrates during exercise and the failure to rec...

The present study examined the effects of varying dietary fat levels on nutrients in female and male endurance runners. Three diets (low, medium and high fat) were designed for each subject using their food preferences and three-day food records. Each diet was eaten for 28 to 31 days. The diets were self-selected from seven-day sample menus. Twelve...

Low dietary fat intake has become the diet of choice for many athletes. Recent studies in animals and humans suggest that a high fat diet may increase VO2max and endurance. We studied the effects of a low, medium and high fat diet on performance and metabolism in runners. Twelve male and 13 female runners (42 miles/week) ate diets of 16% and 31% fa...

Objective: The present study examined the effects of varying dietary fat levels on nutrients in female and male endurance runners. Methods: Three diets (low, medium and high fat) were designed for each subject using their food preferences and three-day food records. Each diet was eaten for 28 to 31 days. The diets were self-selected from seven-day...

Endurance capacity, maximal oxygen uptake capacity (VO2max) and quantitative muscle ultrastructural composition was analyzed in 7 well-trained male runners (mean age 37.1 years, mean VO2max 60 ml/min/kg) after a one month period of a low-fat diet (dietary fat intake 18.4% and a similar period of a high-fat diet (dietary fat intake 40.6%). Between t...

Adherence to dietary goals is a major concern for a nationwide clinical trial to reduce dietary fat in an effort to decrease the incidence of breast and colorectal cancer and cardiovascular disease in 50-79 year old post-menopausal women. A peer group task/cooperative reward structure was compared to a conventional group/individual reward structure...

Chronic exercise and high fat diets are associated with immune suppression. This study compares cellular immune responses at rest and after maximal exercise in runners after eating diets comprised of 17% low fat (LF), 32% medium fat (MF), and 41% high fat (HF) (4 wk each). VO2max increased significantly from the 17% to 41% fat diet. The leukocyte c...

We investigated the effect of dietary fatty acid composition (n-6 vs. n-3) and fiber (highly fermentable vs. less fermentable) on the activities of phospholipase D (PLD) and ornithine decarboxylase (ODC) in the rat large intestine (cecum and proximal and distal colon). Twenty-four Sprague-Dawley rats (215-270 g) ate synthetic diets with 2% safflowe...

Dietary fat may be associated with coronary heart disease (CHD). Studies suggest that restricting fat intake may compromise endurance performance and that increasing fat intake may improve endurance performance. We studied the effects of varying dietary fat intake on CHD risk factors in runners. Twelve male and 13 female runners increased fat from...

Chronic non-specific diarrhea (CNSD) is one of the most common problems seen by pediatric physicians. Its assessment, health consequences, and relationship to dietary practice have not been well-studied The influence of dietary intake on transit time was evaluated for eleven children aged 12 to 36 months (average of 22) with and without CNSD, based...

The objective of the present study was to examine the effect of modifying the fatty acid composition of membranes on cell growth and phosphoinositide specific phospholipase C (PLC) activity in HT-29 colon cancer cells. Cells were seeded at a density of 12 x 10(3) cells/cm2 and supplemented with 30 microM of either 18:0, 18:2 (n6) or 18:3 (n3) compl...

This paper presents a model to evaluate the nutritional status of trained athletes based on work in our laboratory as well as others. The model proposes that substrate use is set by the muscle fibers recruited, based on the exercise intensity. Second, the substrate available is primarily determined by the intramuscular stores. In trained athletes,...