Peter Germonpre

Peter Germonpre
Military Hospital Brussels · Centre for Hyperbaric Oxygen Therapy

MD

About

62
Publications
14,206
Reads
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1,135
Citations
Citations since 2016
14 Research Items
679 Citations
2016201720182019202020212022050100150
2016201720182019202020212022050100150
2016201720182019202020212022050100150
2016201720182019202020212022050100150

Publications

Publications (62)
Article
Patent foramen ovale (PFO) is implicated in the pathogenesis of a number of medical conditions but to date only one official position paper related to left circulation thromboembolism has been published. This interdisciplinary paper, prepared with the involvement of eight European scientific societies, reviews the available evidence and proposes a...
Article
Patent foramen ovale (PFO) is implicated in the pathogenesis of a number of medical conditions but to date only one official position paper related to left circulation thromboembolism has been published. This interdisciplinary paper, prepared with the involvement of eight European scientific societies, reviews the available evidence and proposes a...
Article
Patent foramen ovale (PFO) is implicated in the pathogenesis of a number of medical conditions but to date only one official position paper related to left circulation thromboembolism has been published. This interdisciplinary paper, prepared with the involvement of eight European scientific societies, reviews the available evidence and proposes a...
Article
Full-text available
Background: Primary Spontaneous Pneumothorax (PSP) is considered an absolute and definitive contraindication for scuba diving and professional flying, unless bilateral surgical pleurectomy is performed. Only then is there a sufficiently low risk of recurrence to allow a waiver for flying and/or diving. Case presentation: A young fit male patient...
Article
Full-text available
Introduction: The SARS-CoV2 pandemic has led to an worldwide shortage of Personal Protection Devices (PPD) for medical and paramedical personnel. Adaptation of commercially available snorkel masks to serve as full face masks has been proposed. Even not formally approved as PPD, they are publicized on social media as suitable for this use. Concerns...
Article
Objective: To evaluate the efficiency of percutaneous patent foramen ovale (PFO) closure on the recurrence of decompression illness (DCI). Design: Retrospective, observational study with interview and questionnaire. Setting: Tertiary referral center. Population: 59 scuba divers with a history of DCI who received a percutaneous PFO closure....
Article
The presence of a patent foramen ovale (PFO) is implicated in the pathogenesis of a number of medical conditions; however, the subject remains controversial and no official statements have been published. This interdisciplinary paper, prepared with involvement of eight European scientific societies, aims to review the available trial evidence and t...
Article
The presence of a patent foramen ovale (PFO) is implicated in the pathogenesis of a number of medical conditions; however, the subject remains controversial and no official statements have been published. This interdisciplinary paper, prepared with involvement of eight European scientific societies, aims to review the available trial evidence and t...
Article
The presence of a patent foramen ovale (PFO) is implicated in the pathogenesis of a number of medical conditions; however, the subject remains controversial and no official statements have been published. This interdisciplinary paper, prepared with involvement of eight European scientific societies, aims to review the available trial evidence and t...
Article
Full-text available
Purpose: A reduction in ambient pressure or decompression from scuba diving can result in ultrasound-detectable venous gas emboli (VGE). These environmental exposures carry a risk of decompression sickness (DCS) which is mitigated by adherence to decompression schedules; however, bubbles are routinely observed for dives well within these limits an...
Article
The organs of the ear, nose and throat (ENT) contain air- or gas-filled cavities, which make them sensitive to pressure changes. There is a specific pathophysiology involved when these structures are exposed to non-acoustic press ure changes, which are usually not traumatic in normals. The concepts of pathophysiology, diagnosis and treatment of the...
Article
Although many factors contributing to inert gas narcosis onset and severity have been put forward, the available evidence is not particularly strong. Using objective criteria, we have assessed brain impairment associated with narcosis under various environmental diving conditions. 40 volunteers performed a no-decompression dive (33 m for 20 min) ei...
Article
Full-text available
Diabetic foot ulcers (DFUs) are one of the most common indications for hyperbaric oxygen treatment (HBOT). The role of HBOT in DFUs is often debated. Recent evidence based guidelines, while recommending its use, urge further studies to identify the patient subgroups most likely to benefit from HBOT. A recent study in Diabetes Care aimed to assess t...
Article
ENT indications for Hyperbaric Oxygen Therapy. Hyperbaric Oxygen (HBO) therapy is a treatment where patients breathe 100% oxygen while exposed to high environmental pressure in a hyperbaric chamber. This hyperoxygenation has several beneficial effects as an adjunctive treatment in a number of ENT-related conditions and diseases. These can be summar...
Article
Full-text available
Scuba and breath-hold divers are compared to investigate whether endothelial response changes are similar despite different exposure(s) to hyperoxia. 14 divers (nine scuba and five breath-holding) performed either one scuba dive (25m/25 minutes) or successive breath-hold dives at a depth of 20 meters, adding up to 25 minutes of immersion time in a...
Article
One of the possible risks incurred while diving is inert gas narcosis (IGN), yet its mechanism of action remains a matter of controversy. Although providing insights in the basic mechanisms of IGN, research has been primarily limited to animal studies. A human study, in real diving conditions, was needed. Twenty volunteers within strict biometrical...
Article
Full-text available
This study aims to determine the potential risk factors associated with the development of severe diving-related spinal cord decompression sickness (DCS). Two hundred and seventy nine injured recreational divers (42 ± 12 years; 53 women) presenting symptoms of spinal cord DCS were retrospectively included from seven hyperbaric centers in France and...
Article
The "normobaric oxygen paradox" is a dual mechanism by which oxygen regulates the expression of the Hypoxia Inducible Factor 1 alpha (HIF-1α). The HIF-1α-depending gene regulation is responsible for many different genetic expressions including EPO and VEGF that are usually expressed in parallel. First, VEGF under-expression could decrease tumor ang...
Article
Full-text available
(Lafere P, Balestra C, Hemelryck W, Donda N, Sakr A, Taher A, Marroni S. Germonpre P. Evaluation of critical flicker fusion frequency and perceived fatigue in divers after air and enriched air nitrox diving. Diving and Hyperbaric Medicine. 2010;40(3):114-8.) Introduction: Many divers report less fatigue following dives breathing enriched air nitrox...
Conference Paper
Post decompression records in echocardiography are considered to detect micro bubbles and to survey unexplained decompression sickness which is commonly examined by standardized methods such as dive computers and tables. In this study, existent bubbles are detected on transthoracic echicardiografic frames recorded after recreational diving. Bubble...
Article
Several illnesses such as paradoxical embolism, decompression sickness, migraine and cerebral ischemia are characterized by bubbles which might cross the septum wall between left and right atrium. In this study, we aimed to detect bubbles on echocardiographic frames which are segmented automatically using Snakes method. In recent studies, analyzes...
Article
Full-text available
In our previous research, a deep 5-min stop at 15 msw (50 fsw), in addition to the typical 3-5 min shallow stop, significantly reduced precordial Doppler detectable bubbles (PDDB) and "fast" tissue compartment gas tensions during decompression from a 25 msw (82 fsw) dive; the optimal ascent rate was 10 msw (30 fsw/min). Since publication of these r...
Book
Full-text available
The focus in this new title is on PFO (Patent Foramen Ovale) as a risk factor in diving and thus the text is concerned primarily with dissolved gas and the subsequent aberrant distribution of those venous bubbles in the presence of a natural and common anatomical variant of cardiac development. The prevalence of PFO is about 25% in the general popu...
Article
This update on the latest studies and management policies for patients suffering from sudden sensorineural hearing loss (SSHL) represents a cooperative effort of Belgian ENT surgeons from various corners of the country. SSHL has an incidence ranging from 5 to 20 cases per 100,000 persons per year, and is a relative medical emergency, as only 30% to...
Article
We investigated the effect of secondary hyperbaric oxygen therapy (HBO) for patients with idiopathic sudden sensorineural hearing loss after unsuccessful conventional treatment. We retrospectively evaluated 3 groups: 100 patients without further treatment (group 1), 160 patients with secondary HBO at 1.5 ATA (group 2), and 56 patients with secondar...
Article
SCUBA diving carries with it not only the risks associated with any kind of adventurous outdoor activity, but also some hazards typical of the exposure to high environmental pressure while under water. Through a systematic overview of these hazards, the principles of barotrauma and decompression sickness are explained. Some of the discussion looks...
Article
The use of hyperbaric oxygen therapy as part of the treatment of thermal burns is far from being universally accepted. Although there appears to be substantial experimental animal evidence of the positive effects of hyperbaric oxygen in many aspects of the pathophysiology of the severe burn, the clinical human studies confirming these effects are l...
Chapter
The use of hyperbaric oxygen therapy as part of the treatment of thermal burns is far from being universally accepted. Although there appears to be substantial experimental animal evidence of the positive effects of hyperbaric oxygen in many aspects of the pathophysiology of the severe burn, the clinical human studies confirming these effects are l...
Article
The prevalence of a Patent Foramen Ovale is described in merely 30% of the asymptomatic population. This patency has been shown to be an increasing risk factor for paradoxical cerebral embolization. Some desaturation or decompression situations in human activities such as scuba diving or altitude flight are prone to provoke embolisations. The assoc...
Article
In ordinary recreational scuba diving, many anatomical parts can be involved in disorders of cranial regions: ears and eyes are involved but also sinuses. Dental problems are generally involved in barotraumas because of bad dental fillings or other matters of interest to the general dental practitioner.1 Very few papers have looked at the articular...
Article
Full-text available
In spite of many modifications to decompression algorithms, the incidence of decompression sickness (DCS) in scuba divers has changed very little. The success of stage, compared to linear ascents, is well described yet theoretical changes in decompression ratios have diminished the importance of fast tissue gas tensions as critical for bubble gener...
Article
Full-text available
Scuba divers with patent foramen ovale (PFO) may be at risk for paradoxical nitrogen gas emboli when performing maneuvers that cause a rebound blood loading to the right atrium. We measured the rise and fall in intrathoracic pressure (ITP) during various maneuvers in 15 divers. The tests were standard isometric exercises (control), forceful coughin...
Article
Patency of the foramen ovale (PFO) may be a cause of unexplained decompression sickness (DCS) in sports divers. To assess the relationship between PFO and DCS, a case-control study was undertaken in a population of Belgian sports divers. Thirty-seven divers who suffered from neurological DCS were compared with matched control divers who never had D...
Article
During the first 24 h, a progression of the burn wound in histological depth or extension is often noted. This can only partially be prevented by the routinely used protocols of fluid resuscitation and burn wound dressing. In a rat model of 5% TBSA burn, hyperbaric oxygen therapy (HBOT) and piracetam were evaluated for their ability to further prev...

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Projects

Project (1)
Project
Towards a more personalized evaluation endpoint for decompression stress research - cardiac ultrasound bubble counting evolution post dive - bubble formation and growth modelling