Peter Gergely- MD PhD
- Head of Department at University of Debrecen
Peter Gergely
- MD PhD
- Head of Department at University of Debrecen
About
28
Publications
4,162
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325
Citations
Introduction
forensic medicine all aspects
Current institution
Additional affiliations
March 2019 - present
Position
- Managing Director
Description
- Tr. director, forensic pathologist, medicolegal expert, medicolegal advisor, insurance expert, university teacher, senior lecturer
Education
September 1992 - September 2000
Publications
Publications (28)
Aims. Elevated expression of oncogenes and tumour suppressor genes after treatment with 7,12- dimethylbenz[a]anthracene (DMBA) as early markers of carcinogenesis has been previously observed. The potential antineoplastic and chemopreventive properties of four protein tyrosine kinase (PTK) inhibitor molecules were studied. Materials and methods. In...
Látlelet írása minden orvosi ellátásnak-így a fogorvosi ellátásnak is-a részét képezheti. A látleletet az ellátást végző orvos az ellátási lap alapján a nyomozó hatóság és a bíróság részére hivatalból, a sérült kérésére magánúton köteles kiállítani. A látlelet az orvosi vizsgálat során észleltek mellett a sérülés gyógytartamára vonatkozó orvosi vél...
Hydrogen sulfide (H2S) was revealed to inhibit aortic valve calcification and inflammation was implicated in the pathogenesis of calcific aortic valve disease (CAVD). We investigate whether H2S inhibits mineralization via abolishing inflammation.
Expression of proinflammatory cytokines (IL-1β and TNF-α) was increased in patients with CAVD and in ca...
Hydrogen sulfide (H2S) was previously revealed to inhibit osteoblastic differentiation of valvular interstitial cells (VICs), a pathological feature in calcific aortic valve disease (CAVD). This study aimed to explore the metabolic control of H2S levels in human aortic valves. Lower levels of bioavailable H2S and higher levels of interleukin-1β (IL...
A hazai igazságügyi orvosszakértői gyakorlat segítése, a szakértők és a jogalkal-mazók tájékoztatása, továbbá az igazságügyi orvosszakértői véleményalkotás egységesítése céljából a BM Egészségügyi Szakmai Kollégium Igazságügyi Orvostan, Orvosszakértés és Biztosítási Orvostan Tagozata, az orvostudományi egyetemek igazságügyi orvostani intézetei (Deb...
Vulnerable atherosclerotic plaques, especially hemorrhaged lesions, are the major cause of mortalities related to vascular pathologies. The early identification of vulnerable plaques helps to stratify patients at risk of developing acute vascular events. In this study, proteomics analyses of human carotid artery samples collected from patients with...
In Hungary, possessing certain weapons (e.g. firearms, bows, air pistols, and air guns mainly over 7.5 Joule muzzle velocity) is strictly regulated. In case of firearm deaths, in our country, we usually have to consider the role of military personnel or a hunter. Getting a game license for five years is a complex procedure. Class participation in w...
The emergence of newer SARS-CoV-2 variants of concern (VOCs) profoundly changed the ICU demography; this shift in the virus’s genotype and its correlation to lethality in the ICUs is still not fully investigated. We aimed to survey ICU patients’ clinical and laboratory parameters in correlation with SARS-CoV-2 variant genotypes to lethality. 503 CO...
A 15-year-old young girl was found dead at home. There were no indications of any intervention or the application of force. On the previous day, she was admitted to hospital because of palpitations, fatigue, a headache, and a swollen neck. During a physical examination, a swollen thyroid gland and tachycardia were found. In the family history, her...
Background
Hidradenitis suppurativa (HS) is a chronic, inflammatory disease of the apocrine gland-rich (AGR) skin region. The initial steps of disease development are not fully understood, despite intense investigations into immune alterations in lesional HS skin.
Objectives
We aimed to systematically investigate the inflammatory molecules involve...
Aim:
Infiltration of red blood cells in atherosclerosis is correlated with the development of complicated lesions. In this study, we examined whether oxidation of hemoglobin (Hb) contributes to transformation of lesions towards a progressive phenotype.
Results:
We observed that macrophages engulf then internalize ferrylHb generated in hemorrhagi...
Infiltration of red blood cells into atheromatous plaques and oxidation of hemoglobin (Hb) and lipoproteins are implicated in the pathogenesis of atherosclerosis. α1-microglobulin (A1M) is a radical-scavenging and heme-binding protein. In this work, we examined the origin and role of A1M in human atherosclerotic lesions. Using immunohistochemistry,...
Tyrosine kinases play crucial roles in cellular development and tumorigenesis. Tyrosine kinase inhibitors (TKIs) are effective and widely used drug molecules in targeted cancer therapies. Altered expressions of protooncogenes and tumor suppressor genes after DMBA (7,12-dimethylbenz[a]anthracene) treatment have been described as early markers of tum...
The documents included 352 injuries (11.1% of which were tooth injuries, 47.7% bone injuries and 41.2% soft-tissue injuries). The low number of attributes per injury (0.64 on average) indicates insufficient documentation. As a result of the comparative analysis, significant differences were found between the documentation of dental injuries and tha...
A pontatlan orvosi szakkifejezések használatának hatása a büntetõeljárás kimenetelére A sérüléseket ellátó orvosok gyakran nincsenek tudatában, milyen jogi következményekkel járhat, ha a dokumentáció készítésekor csak a gyakorlati szempontokat veszik figyelembe. Jelen tanulmány célja a baleseti sebészeti ambulanciákon keletkezett látleletek büntetõ...
Melanin-concentrating hormone (MCH) is a cyclic 19 amino acid orexigenic hypothalamic peptide. MCH is located in the lateral and dorsal hypothalamus, as well as in the zona incerta. In mammals MCH increases food intake, contributes to regulation of energy balance, temperature, reproductive function, endocrine homeostasis and biological rhythms. Sev...
The mesolimbic reward pathway arising from dopaminergic (DA) neurons of the ventral tegmental area (VTA) has been strongly implicated in reward processing and drug abuse. In rodents, behaviors associated with this projection are profoundly influenced by an orexinergic input from the lateral hypothalamus to the VTA. Because the existence and signifi...
Previous immunohistochemical and in situ hybridization studies of sheep, goats, and rodents indicated that kisspeptin (KP), neurokinin B (NKB), and dynorphin A (DYN) are extensively colocalized in the hypothalamic arcuate nucleus, thus providing a basis for the KP/NKB/DYN (KNDy) neuron concept; in both sexes, KNDy neuropeptides have been implicated...
Aim. We tested the applicabilityy of expression ofonco/tumor suppressor genes as biomarkers for monitoring the therapeutical efficacy of colorectal cancer, and compared it with traditional tumor markers (CA19-9 and CEA) and with the total blood antioxidant capacity. Materials and methods. In our follow-up study the expression of oncogenes and tumor...
A long-term experimental animal model was developed by our research group for the evaluation of potential chemopreventive effects. The inhibitory effects of agents on carcinogen (7,12-dimethylbenz[a]anthracene (DMBA) induced molecular epidemiological biomarkers, in this case the expression of key onco/suppressor genes were investigated.
The express...
