Pedro Luiz Mailho-Fontana

Pedro Luiz Mailho-Fontana
Instituto Butantan | butanan · Laboratório de Biologia Celular

About

26
Publications
14,068
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297
Citations
Citations since 2016
20 Research Items
276 Citations
20162017201820192020202120220102030405060
20162017201820192020202120220102030405060
20162017201820192020202120220102030405060
20162017201820192020202120220102030405060
Introduction

Publications

Publications (26)
Article
Full-text available
Despite the common poison and mucous glands, some amphibian groups have differentiated glands associated with reproduction and usually present on the male ventral surface. Known as breeding glands or sexually dimorphic skin glands (SDSGs), they are related to intraspecific chemical communication during mating. Until recently, reproduction associate...
Article
Full-text available
Citation: Mauricio, B.; Mailho-Fontana, P.L.; Sato, L.A.; Barbosa, F.F.; Astray, R.M.; Kupfer, A.; Brodie, E.D.J.; Jared, C.; Antoniazzi, M.M. Morphology of the Cutaneous Poison and Mucous Glands in Amphibians with Particular Emphasis on Caecilians (Siphonops annulatus). Toxins 2021, 13, 779. https:// Abstract: Caecilians (order Gymnophiona) are ap...
Article
Full-text available
AbstractToads are considered poisonous animals since they have a passive mode of defence relying on cutaneous poison glands, differently from venomous animals who can inject venom in predators/aggressors or prey. Toads of Rhinella marina group are generally large and have a broad distribution in South America, inhabiting a wide range of environment...
Article
Full-text available
We discuss the use of the terms venom and poison, in the context of integrative biology, with particular emphasis on behaviour and natural history. Our purpose is to reach a broad scientific audience, especially that dedicated to zoology. The meaning of the two terms is reviewed from the secretory perspective, mainly focussed on the reptiles and am...
Article
Full-text available
Amphibians are known for their skin rich in glands containing toxins employed in passive chemical defense against predators, different from, for example, snakes that have active chemical defense, injecting their venom into the prey. Caecilians (Amphibia, Gymnophiona) are snake-shaped animals with fossorial habits, considered one of the least known...
Article
Full-text available
Amphibian cutaneous glands secrete toxins used in different vital functions including passive defense. Through Desorption Electrospray Ionization-Imaging we analyzed the distribution of the major toxins of the toad Rhinella marina parotoid macroglands. Alkaloids and steroids showed characteristic distribution and intensity within the glands and wer...
Article
In recent years, SE Brazil, the most populous region in the country with an estimated population of 88 million, has been experiencing an alarming increase in scorpions accidents (scorpionism), mainly caused by the yellow scorpion (Tityus serrulatus), or "escorpião amarelo" in Portuguese. This species is considered particularly dangerous to humans a...
Article
Full-text available
Tetrodotoxin (TTX), one of the most toxic substances in nature, is present in bacteria, invertebrates, fishes, and amphibians. Marine organisms seem to bioaccumulate TTX from their food or acquire it from symbiotic bacteria, but its origin in amphibians is unclear. Taricha granulosa can exhibit high TTX levels, presumably concentrated in skin poiso...
Presentation
Full-text available
Nature Highlights - Hardy Brazilian frogs dig deep to escape drought.
Article
The semi‐arid region (Caatinga), that corresponds to 18.26% (1,540,000 km²) of Brazil, occupies most the northeast region. Rainfall is irregular and concentrated within the first 3 months of the year. Prolonged periods of drought, with low total rainfall, may extend for two or more years. Most of the rivers of this biome are temporary, remaining to...
Article
Full-text available
Background Amphibian defence against predators and microorganisms is directly related to cutaneous glands that produce a huge number of different toxins. These glands are distributed throughout the body but can form accumulations in specific regions. When grouped in low numbers, poison glands form structures similar to warts, quite common in the do...
Presentation
Full-text available
https://www.nature.com/articles/d41586-018-04257-3
Article
Due to their mainly fossorial way of life, caecilian amphibians are the least known order of terrestrial vertebrates. Here, we present new observations on the natural history and reproductive biology of the neotropical oviparous, siphonopid caecilian Siphonops annulatus from a long‐term study of this species in the field and in captivity. In the st...
Article
Full-text available
Amphibian skin is rich in mucous glands and poison glands, secreting substances important for gas exchange and playing a fundamental role in chemical defense against predators and microorganisms. In the caecilian Siphonops annulatus (Mikan, 1920) we observed a concentration of enlarged mucous glands in the head region. In the posterior region of th...
Article
Toads have a pair of glandular accumulations on each side of the dorsal region of the head known as parotoid macroglands. These macroglands consist of secretory units (granular glands), each one capped with an epithelial plug. When threatened, toads point one of the parotoids toward the aggressor, and if the aggressor squeezes the parotoid with its...
Article
Anuran integument is characterized by the presence of glands, some of which are responsible for toxin production. In some species these glands accumulate in parts of the body strategically located against predators, forming structures known as macroglands. This is the case for parotoid macroglands, on the dorsum of the head, tibial macroglands, on...
Article
Several reports are available regarding ticks parasitizing toads of the family Bufonidae. Although ticks can attach to different regions of the body, occurrence of these ectoparasites on parotoid macroglands is unfrequent when compared with other regions of body. In this study, using histology and scanning electron microscopy, we analysed a rare ca...
Article
Full-text available
Venomous animals have toxins associated with delivery mechanisms that can introduce the toxins into another animal [1]. Although most amphibian species produce or sequester noxious or toxic secretions in the granular glands of the skin to use as antipredator mechanisms [2, 3], amphibians have been considered poisonous rather than venomous because d...
Presentation
Full-text available
https://www.nature.com/articles/524139c
Article
Toads have a pair of parotoid macroglands behind the eyes that secrete poison used in passive defence against predators. These macroglands are composed of juxtaposed alveoli, each one bearing a syncytial gland, all connected to the exterior by ducts. When the parotoids are bitten, the poison is expelled on the predator oral mucosa in the form of je...
Article
Amphibians have many skin poison glands used in passive defense, in which the aggressor causes its own poisoning when biting prey. In some amphibians the skin glands accumulate in certain regions forming macroglands, such as the parotoids of toads. We have discovered that the toad Rhaebo guttatus is able to squirt jets of poison towards the aggress...
Article
The parotoid macroglands of toads (bufonids) and leaf frogs (hylids) are used in passive defence against predators. The parotoids release poison when the amphibian is bitten by a predator. Despite the apparent similarity, the anatomical and histological structure of these macroglands in hylids is poorly studied when compared with those of bufonids....
Article
Full-text available
INTRODUÇÃO A coleta seletiva consiste na separação de materiais recicláveis, como plásticos, vidros, papéis, metais, nas várias fontes geradoras – residências, empresas, escolas, comércio, indústrias, unidades de saúde –, tendo em vista a coleta e o encaminhamento para a reciclagem. Esses materiais representam cerca de 30 por cento da composição do...

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Projects

Project (1)
Project
We have worked mainly in the morphology of venom (or poison) glands in amphibians and reptiles trying to correlate to biology and natural history. This project will also explore biochemically the secretion of integumentary glands (and macroglands) of Amphibia.