Pedro LopezEdith Cowan University · Exercise Medicine Research Institute
Pedro Lopez
PhD student
About
52
Publications
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Introduction
Pedro Lopez is a PhD student at the Exercise Medicine Research Institute (EMRI/ Edith Cowan University). His field of investigation is concerning the moderators of exercise effects in different clinical populations including cancer patients and older adults, aiming to elucidate the circumstances what exercise derives clinically meaningful benefits on health-related, patient-report and clinical outcomes.
Additional affiliations
August 2017 - August 2019
Publications
Publications (52)
Purpose:
Resistance training (RT) improves an array of treatment-related adverse effects in men with prostate cancer, however, the minimal dosage required is unknown. We systematically reviewed the RT effects in prostate cancer patients to determine the minimal dosage regarding the exercise components (type, duration, volume, and intensity) on bod...
Background
Active treatments for prostate cancer are well known to result in several adverse effects such as fatigue, depression and anxiety symptoms, impacting the overall quality of life (QoL) and wellbeing of a considerable proportion of patients. Resistance-based exercise interventions have shown positive effects to reduce or mitigate these tre...
Background
To systematically review and analyse the associations between fat and muscle mass measures with overall survival in men with prostate cancer.
Methods
A systematic search was conducted in CINAHL, Cochrane Library, EMBASE, PubMed, and Web of Science databases from inception to December 2020, while abstracts from the American Society of Cl...
Purpose: To perform a systematic review and network meta-analysis to investigate the most effective intervention for improving body composition outcomes in prostate cancer patients during or following treatment.
Methods: A systematic search was undertaken in multiple databases from inception to December 2020. Randomized clinical trials examining th...
To systematically review and analyze the effects of resistance-based exercise programs on body composition, regional adiposity, and body weight in individuals with overweight/obesity across the lifespan. Using PRISMA guidelines, randomized controlled trials were searched in nine electronic databases up to December 2020. Meta-analyses were performed...
Introduction
Obese men with prostate cancer have an increased risk of biochemical recurrence, metastatic disease and mortality. For those undergoing androgen deprivation therapy (ADT), substantial increases in fat mass are observed in the first year of treatment. Recently, we showed that a targeted supervised clinic-based exercise and nutrition int...
Objectives/background
The prevalence of obstructive sleep apnea (OSA) in people over 70 years can reach up to 95%. Aerobic or combined exercise programs have been shown to impact positively on OSA severity. Resistance training changes leg fluid retention. We hypothesized that through this mechanism it may have an impact on the OSA severity in older...
Background
Muscle strength imbalance assessment (e.g., hamstring-to-quadriceps ratio, H:Q) using traditional peak torque isokinetic measurements has been shown to be a weak risk factor predictor of future lower-limb injuries (e.g., hamstring strain and anterior cruciate ligament tear). In soccer, power-related tasks are commonplace and injuries are...
Purpose
Strength training is performed using multi-joint (MJ) or single-joint (SJ) exercises; however, it is not clear whether different time of recovery is necessary between the two types of exercise. The aim of the present study was to compare the time course of recovery of indirect markers of exercise-induced muscle damage (EIMD) in the elbow fl...
To systematically review and analyse the effects of exercise on morphological and neuromuscular muscle quality (MQ) outcomes in older adults and assess a range of possible moderators that may affect the impact of exercise on MQ outcomes. Using PRISMA guidelines, randomised controlled trials were searched in CINAHL, EMBASE, LILACS, PubMed, SciELO, W...
Objetivo: Descrever os efeitos e os moderadores do exercício físico na fadiga e capacidade cardiorrespiratória de pacientes com câncer de mama em tratamento primário, bem como a relação entre o exercício físico e sobrevida nessa população.
Métodos: Foi realizada uma revisão narrativa de estudos que examinaram os efeitos do exercício na fadiga e cap...
Purpose
Although exercise medicine is recommended to counter treatment-related side-effects and improve health-related outcomes of patients affected by different cancers, no specific recommendations exist for patients with melanoma. As a result, we systematically examined the current evidence regarding the effects of physical activity and exercise...
The aim of this study was to examine the health-related effects of exercise in patients with pancreatic cancer (PanCa) through a systematic review of current evidence. Studies were obtained through searching PubMed, Web of Science, PsycINFO, Embase, CINAHL Plus, and Cochrane Library databases with additional hand searches. All intervention-based st...
Purpose: To analyse the effect of resistance training (RT) performed until volitional failure with low-, moderate- and high-loads on muscle hypertrophy and muscle strength in healthy adults; and assess the possible participant-, design-, and training-related covariates which may affect the adaptations.
Methods: Using PRISMA guidelines, MEDLINE, CIN...
In the original paper, the surnames of some of the authors were not presented correctly. The correct names are presented here. The following is the correct citation for this paper:
Krüger, R.L., Teixeira, B.C., Farinha, J.B., Macedo, R.C.O., Boeno, F.P., Rech, A., Lopez, P., Pinto, R.S., and Reischak-Oliveira, A. 2016. Effect of exercise intensity...
Abstract
In this brief correspondence, we evaluate the potential impact of pivoting from face-to-face supervised to unsupervised home-based exercise programmes to contextualise the coronavirus disease 2019 (COVID-19) pandemic in prostate cancer patients. A meta-analysis was undertaken in fatigue, quality of life, and lean and fat mass outcomes in t...
Background
Exercise is recognised as an adjunct therapy for breast cancer patients; however, little is known about the resistance training dose–response. We conducted a systematic review and meta-regression to examine the resistance training dose–response (i.e., volume and intensity) in breast cancer patients undergoing primary treatment.Methods
Se...
This study investigated the effects of a 11-week moderate-to-heavy sled training intervention with different magnitudes of velocity loss on sprint and jump performance, mechanical muscle function, and body composition in professional soccer players. Seventeen players (age 25.8±4.3 years; height 180.0±8.6 cm; weight 77.7±9.7 kg) were randomly
alloc...
This study investigated the effects of concurrent training performed either with repetitions to failure or not to failure in muscle power, muscle quality (MQ), peak oxygen uptake (VO2peak), and visceral fat in older men. This is an ancillary analysis of a randomized controlled trial. 36 older men (mean age ± SD; 67.1 ± 5.1 years) were randomized in...
The present study examined 8 weeks of resistance training and its effects on muscle quality measures, plantar flexor muscle strength, muscle thickness and functional capacity in older women. Moreover, we tested if changes in muscle quality were associated with functional capacity. Twenty-four older women (66.3 ± 5.8 years; 69.0 ± 3.0 kg; 25.3 ± 1.4...
This randomized clinical trial compared the neuromuscular adaptations induced by concurrent training (CT) performed with repetitions to concentric failure and not to failure in elderly men. Fifty-two individuals (66.2 ± 5.2 years) completed the pre- and post-measurements and were divided into three groups: repetitions to failure (RFG, n = 17); repe...
Abstract
Background: Some athletes have been particularly adopted
personal strength and conditioning coaches during their
day to day routines. However, there are no studies about
this complementary management. The present study aimed
to screen injury incidence, match play, and market value
parameters of topelite soccer players during seasons with
a...
The present study compared the effects of 12 weeks of muscle power training performing one or three sets on muscle quality assessed by echo intensity (MQEI) and index (MQindex), muscle power-related outcomes, and functional capacity in older women. Participants were randomly assigned into two groups: 1SET (n = 13) and 3SET (n = 13). Lower limb musc...
The present study compared the effects of 12 weeks of muscle power training performing one or three sets on muscle quality assessed by echo intensity (MQEI) and index (MQindex), muscle power-related outcomes, and functional capacity in older women. Participants were randomly assigned into two groups: 1SET (n = 13) and 3SET (n = 13). Lower limb musc...
Please, visit https://lume.ufrgs.br/handle/10183/199316# for full-text access.
Best regards,
Pedro Lopez
This study compared the effects of 20 weeks of concurrent training with and without repetitions to failure on neuromuscular and functional adaptations in older men.
Methods
Thirty‐six older men (67.1 ± 5.1 years) were randomized into three groups: one performing repetitions to failure (RFG, n = 13), another performing repetitions not to failure an...
Regular resistance exercise is associated with metabolic, neuromuscular and cardiovascular adaptations which improve quality of life and health. However, sedentary subjects have shown acute impairments in endothelial function after high-intensity resistance exercise. The aim of this study was to evaluate endothelial function in sedentary middle-age...
Match-induced fatigue of knee muscle strength and agonist-antagonist strength-ratios may affect both performance and risk of injury in soccer players. Once explosive tasks are imperative in soccer as well as hamstring strain injuries occur during high-velocity moments, rapid force capacity of this muscle group is especially important. This study ev...
Introduction:
Understanding the recovery in response to different sprint protocols is important for optimizing neuromuscular gains and organizing training sessions in sports. The current study aimed to investigate acute neuromuscular changes following a moderate volume of sprint protocols with and without change-of-direction.
Methods:
26 well-tr...
Purpose:
To evaluate the effects of 12-weeks of strength training on endothelial function and inflammatory markers in elderly individuals with T2DM.
Methods:
Forty-four elderly patients with T2DM were screened for participation. After completion of the baseline assessment, participants were randomly assigned to either the resistance training gro...
Lanferdini, FJ, Manganelli, BF, Lopez, P, Klein, KD, Cadore, EL, and Vaz, MA. Echo intensity reliability for the analysis of different muscle areas in athletes. J Strength Cond Res 33(12): 3353-3360, 2019-Skeletal muscles' echo intensity (EI) is used as a parameter to evaluate muscle damage and muscle quality after exercise or training. However, re...
In the work described here, our aim was to determine, in an elderly population, changes in muscle thickness (MT), cross-sectional area (CSA) and echo intensity (EI) of the quadriceps muscles at four time points (0, 5, 10 and 15 min; i.e., T0, T5, T10 and T15, respectively) after changing from a standing to supine position. Twenty-one elderly partic...
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Aim:
Exercise is one of the most important components in frailty prevention and treatment. Therefore, we systematically reviewed the effect of resistance training (RT) alone or combined with multimodal exercise intervention on muscle hypertrophy, maximal strength, power output, functional performance, and falls incidence in physically frail elderl...
• Heat Shock Response (HSR) is similar in healthy middle-aged and elderly people, but is blunted in aged individuals with T2DM.
• Visceral Adipose Tissue (VAT) is increased with age, and the increased VAT is correlated with a lower HSR.
• Resistance training (RT) is an efficient intervention to restore the HSR and reduce inflammation in aged indi...
Isokinetic hamstring to quadriceps ratios are frequently used to assess knee muscle strength
imbalances and risk of injuries/re-injuries. The use of peak torque (PT) or total work (TW) to
estimate joint stability may lead to different results because of the differences between these
two neuromuscular variables. Thus, the current study aimed to comp...
Study Objectives
Interventions that decrease leg fluid retention reduce obstructive sleep apnea (OSA) severity in nonrandomized experiments. We aimed to investigate in a randomized trial the effect of interventions that reduce fluid volume on OSA severity.
Methods
Men diagnosed with severe OSA were randomized to receive daily spironolactone 100 mg...
Background
Obstructive sleep apnea (OSA) occurs due to sleep-induced upper airway muscle relaxation resulting in increased pharyngeal collapsibility. Clinical trials have shown a favorable effect of exercise training on OSA severity in middle-aged adults. Aging is characterized by motor-unit loss. Force training may affect the whole body muscle ton...
A fragilidade é uma síndrome que atinge idosos, impactando de forma negativa a sua saúde. O exercício físico é um dos mais importantes componentes na prevenção e tratamento da fragilidade, sendo o treinamento de força (TF) um dos principais tipos de intervenção para esta população. Assim, o objetivo deste estudo é analisar os efeitos do TF realizad...
![Table 1 . Search Strategy #1 Frail Older [MeSh]: Elderly, Frail OR...](profile/Pedro-Lopez-12/publication/320074071/figure/tbl1/AS:667793619943433@1536225814751/Search-Strategy-1-Frail-Older-MeSh-Elderly-Frail-OR-Frail-Elders-OR-Elder-Frail_Q320.jpg)
In this meta-analysis, we investigated the effect of resistance training (RT) alone, or included in a multimodal training on physical frailty outcomes, and whether different variables of RT prescription affect these outcomes. We identified 15 relevant studies searching through MEDLINE, Cochrane Central, SPORTDiscus and PEDro database. Post-interven...
Introduction:
The aim of this study was to examine the associations between quadriceps muscle functionality features in non-active older men to determine predictors of functional performance.
Methods:
Quadriceps functional parameters, including quadriceps echo intensity (QEI), rate of torque development (RTD), and the 30 second sit to stand test...
The aim of this study was to compare the effects of 2 different exercise intensities on postprandial lipemia, oxidative stress markers, and endothelial function after a high-fat meal (HFM). Eleven young men completed 2-day trials in 3 conditions: rest, moderate-intensity exercise (MI-Exercise) and heavy-intensity exercise (HI-Exercise). Subjects pe...
The aim of this study was to compare the muscle thickness (MT), muscle
quality (MQ), and functionality of two different age groups of active elderly women.
Twenty seven older women (between 60 and 80 years old), physically active was dividing
in two age groups: old 60-66 years (Old) and old 73-80 years (Older) volunteered
for the present study. Kne...
Introduction
Among the mechanisms causing hypertension in obstructive sleep apnea (OSA) patients, the roles of hypoxia and of arousals, leading to intermittent oxidative stress and repeated elevations of blood pressure, have been difficult to disentangle. The apnea–hypopnea index (AHI) reflects the number of arousals. The minimum arterial oxygen sa...
Questions
Question (1)
Hi RG fellows,
I'm looking for further information regarding the classic fail-safe N method (i.e., to calculate the minimum number of undetected negative studies that would be needed to change the conclusions of a meta-analysis) for network meta-analysis. The application of this method in meta-analysis is usual but I didn't find further information for network meta-analysis... Is this possible? If yes, which package or software is recommended?
Thanks in advance.
Pedro Lopez
Projects
Projects (3)
The present study compared the effects of 12 weeks of muscle power training performing one or three sets on muscle quality assessed by echo intensity (MQEI) and index (MQindex), muscle power-related outcomes, and functional capacity in older women. Participants were randomly assigned into two groups: 1SET (n = 13) and 3SET (n = 13). Lower limb muscle power and vertical jump height were measured during a countermovement jump, maximal rate of torque development (MRTD), and root mean square (RMS) of electromyography signals
and rate of rise (RER) of quadriceps maximal electromyography activation during unilateral knee extension at 0–50 and 0–200 ms, MQEI, MQindex (absolute muscle power/MQEI, and MRTD/MQEI) and functionally in both groups using timed-up-and-go were evaluated before and after training.
The aim of this study was to compare the effects of 12 weeks of muscle power training using one- and three-sets on neuromuscular adaptations in elderly women. Twenty six healthy elderly women were randomly assigned into two groups: one-set (n = 13) and three-sets (n = 13). Maximal dynamic and isometric strength, rapid force assessed as absolute and normalized rate of force development (RTD) and contractile impulse during unilateral leg knee extension at 0–50 and 0–200 ms, overall quadriceps muscle thickness, muscle power during a countermovement jump (CMJ), and functional performance using time-up-and-go and the timed stair climb tests were evaluated before and after training. After 12 weeks, one-set and three-sets groups exhibited significant (p ≤ 0.05) and comparable increases in dynamic and isometric strength, absolute RTD and contractile impulse at 0–50 and at 0–200 ms and in the performance of both functional tests
This study aims to investigate the effects of different volumes of combined training on fatigue, neuromuscular variables, morphological, cardiorespiratory capacity, and quality of life, in breast cancer (BCa) women undergoing primary treatment.
