
Payam BEHZADIIslamic Azad University, Shahr-e-Qods Branch
Payam BEHZADI
Ph.D. in Molecular Biology
Team Leadership, Supervision, High-Quality Research and Publication; International Scientific Collaboration
About
197
Publications
116,722
Reads
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3,727
Citations
Introduction
Additional affiliations
July 2004 - present
Shahr-e-Qods Branch; Islamic Azad University
Position
- Professor (Assistant)
March 2017 - March 2020
Islamic Azad University, Shahr-e-Qods Branch
Position
- Professor (Assistant)
July 2004 - present
Islamic Azad University, Shahr-e-Qods Branch
Position
- Faculty Member
Education
September 2012 - February 2016
Molecular Biology Research Center, Baqiyatallah University of Medical Sciences
Field of study
- Molecular Biology
September 2000 - June 2002
Islamic Azad University, North Tehran Branch
Field of study
- Microbiology
September 1996 - February 2000
Islamic Azad University, North Tehran Branch
Field of study
- Microbiology
Publications
Publications (197)
Editorial
2024 Acknowledgment of mSystems Ad Hoc Reviewers
Jack A. Gilbert,1 Editor in Chief, mSystems
BIOINFORMATICS 2025 - Program Committee Member Certificate
Gut microbiota and immunity in health and disease: dysbiosis and eubiosis’s effects on the human body
Summary
Background Diarrhoeal diseases claim more than 1 million lives annually and are a leading cause of death in children
younger than 5 years. Comprehensive global estimates of the diarrhoeal disease burden for specific age groups of
children younger than 5 years are scarce, and the burden in children older than 5 years and in adults is also
un...
Editorial: Gut microbiota and immunity in health and disease: dysbiosis and eubiosis’s effects on the human body
Melanoma, a highly aggressive form of skin cancer, poses a significant global health burden, with 331,647 new cases and 58,645 deaths reported in 2022. The development of melanoma is influenced by various factors, including sunlight exposure and BRAFV600 mutations that activate the MAPK/ERK pathway. The introduction of BRAF and MEK inhibitors has r...
Since the last century, antibiotics have been our re-
liable weapons against infectious diseases. In addition
to their medicinal applications in human and veterinary
medicine, antibiotics are also used in agriculture. How-
ever, the uncontrolled usage of antibiotics has led to the
emergence of drug-resistant microbial strains and the rise of
their...
August 2024 data-update for "Updated science-wide author databases of standardized citation indicators"
Background
In the present study, we aimed to determine the frequency of the csgA, fimH, mrkD, foc, papaGI, papGII and papGIII genes, to provide and to design fimbrial adhesin gene (FAG) patterns and profiles for the isolated uropathogenic Escherichia coli (UPEC) strains.
Methods
The enrollment of 108 positive urine samples was performed during sev...
This mini-review explores the role of short-chain fatty acids (SCFAs) in posttraumatic stress disorder (PTSD). Highlighting the microbiota-gut-brain axis, this study investigated the bidirectional communication between the gut microbiome and mental health. SCFAs, byproducts of gut microbial fermentation, have been examined for their potential impac...
Summary
Background Future trends in disease burden and drivers of health are of great interest to policy makers and the public
at large. This information can be used for policy and long-term health investment, planning, and prioritisation. We
have expanded and improved upon previous forecasts produced as part of the Global Burden of Diseases, Injur...
Summary
Background
Future trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and prioritisation. We have expanded and improved upon previous forecasts produced as part of the Global Burden of Diseases, Injur...
Candida albicans is a member of the human host's microbiome composition; therefore, it is recognized as a portion of the human host body's normal flora in a homeostasis condition. However, when the host develops an abnormal condition, e.g., immune deficiency, C. albicans acts as an opportunistic pathogen. C. albicans has an effective arsenal of a w...
Leptospirosis, one of the most common global zoonotic infections, significantly impacts global human health, infecting more than a million people and causing approximately 60,000 deaths annually. This mini-review explores effective treatment strategies for leptospirosis, considering its epidemiology, clinical manifestations, and current therapeutic...
Acinetobacter baumannii is a Gram-negative pathogen responsible for a variety of community-and hospital-acquired infections. It is recognized as a life-threatening pathogen among hospitalized individuals and, in particular, immunocompromised patients in many countries. A. baumannii, as a member of the ESKAPE group, encompasses high genomic plastici...
The level of synergies between the human host and gut microbiota is frequently underestimated: growing evidence demonstrates a multi-faceted interplay influencing health status stability of the host, health-to-disease transition, disease severity grad, therapy-resistance and individual outcomes. Moreover, a powerful instrument has been established...
Aims: In this study, five essential oils (EOs) from different species
of Lavandula hybrida abrialis, for Lavandula hybrida R.C., Lavandula
hybrida ‘super A’, Lavandula hybrida ‘super Z’ and Lavandula vera
and its hybrids Lavender were evaluated against 26 dust-isolated
fungal strains from North Africa.
Methods and results: The composition of the di...
Background and Objective: This review comprehensively explores the intricate landscape of anaplastic lymphoma kinase (ALK), focusing specifically on its pivotal role in non-small cell lung cancer (NSCLC). Tracing ALK’s discovery, from its fusion with nucleolar phosphoprotein (NPM)-1 in anaplastic large cell non-Hodgkin’s lymphoma (ALCL) in 1994, th...
The current review comprehensively explores the multifaceted landscape of anaplastic lymphoma kinase (ALK) and its pivotal role, specifically within non-small cell lung cancer (NSCLC). It traces the trajectory of ALK's discovery, notably its fusion with nucleolar phosphoprotein (NPM)-1 in anaplastic large cell non-Hodgkin's lymphoma (ALCL) in 1994....
Infective endocarditis is a devastating disease that affects the heart´s inner lining, typically due to bacterial infections. The infection harms the valves, causing them to leak, and creates clots that move to other organs, including the brain. Patients with congenital heart disease and prosthetic valves and those who use intravenous drugs are at...
KEYWORDS innate immunity, adaptive immunity, human urinary system, nervous system, interleukins, toll-like receptors, cytokines
World's Top 2% Most-cited Scientists by Stanford University Ranking 2023 (Scopus)
Toll-like receptors (TLRs) serve as the body’s first line of defense, recognizing both pathogen-expressed molecules and host-derived molecules released from damaged or dying cells. The wide distribution of different cell types, ranging from epithelial to immune cells, highlights the crucial roles of TLRs in linking innate and adaptive immunity. Upo...
Background:
Today, uterine cancer is one of the most important causes of death in the world and is one of the major problems in human health. There have been numerous reports of the effect of Streptococcus agalactiae peptide and capsular products against cancer cell lines. Objective: This study aimed to research recombinant peptide CPSA-CPSC-L-ACA...
Background
Cervical cancer is the fourth most common cause of cancer and the fourth most common cause of cancer deaths in women. Some reports have shown the effect of Streptococcus agalactiae proteins and capsule products against cancer cell lines.
Methods
This study aimed to design and produce a fusion of recombinant protein (containing the capsu...
Introduction: Cancer is a complex disease influenced by genetics and environmental factors, registering a high annual mortality rate worldwide.
Despite significant advances in cancer treatment, conventional drug therapies for various cancers have many side effects. Today, the use of complementary medicine is prevalent. Curcumin, as a polyphenol, ha...
Background
Cancer is the second leading cause of death among men and women and a highly prevalent cause of mortality among women. Having sexual relations at a young age, having multiple sex partners, multiple pregnancies, long-term use of birth control pills, receiving a kidney transplant, and sexually transmitted diseases (STDs) are the major risk...
Increasing the resistance of microorganisms to common antibiotics has led to the discovery of new antimicrobial compounds. Antimicrobial peptides are a suitable option to replace existing antibiotics. Capsular synthesizing enzyme peptides with the ACAN antibacterial sequence are a group of bioactive peptides. In this study, the antimicrobial functi...
The concern of antimicrobial resistance (AMR) is considered to feature among the to
threats to global health (World Health Organization, 2019, 2022). Several issues are recognized
as relevant etiologic factors in the emergence of AMR, including worldwide misuse or overuse
of antibiotics. According to recorded reports, low- and middle-income countri...
Klebsiella pneumoniae is a Gram-negative opportunistic pathogen responsible for a variety of community and hospital infections. Infections caused by carbapenem-resistant K. pneumoniae (CRKP) constitute a major threat for public health and are strongly associated with high rates of mortality, especially in immunocompromised and critically ill patien...
There are several treatments for cancer, including medication, surgery, chemotherapy, radiation therapy, and targeted therapy. Although these methods are common among cancer treatments, they can cause side effects such as resistance to treatment and damage to non-cancerous cells, and other adverse effects on the cells. This study aimed to evaluate...
There have been numerous reports of the effect of the Streptococcus agalactiae peptide and its capsule products on cervical cancer. This study aimed to investigate the inhibitory effect of the recombinant anti-cancer protein CpsA-CpsC-L-ACAN on the HeLa cell. The CpsA-CpsC-L-ACAN sequence construction was obtained from NCBI. The Structure of CpsA-C...
Prostate cancer (PCa) is a huge concern among men worldwide, especially in global industrial regions. In recent years, the incidence of PCa has been growing up in Asian countries, too. Although the PCa is a multifactorial malignancy, the immunogenetic factors are highlighted as considerable items. Due to this fact, I as the author of this chapter w...
Background: Multi-drug resistant (MDR) Klebsiella pneumoniae strains cause the majority of community acquired and life-threatening infections. We aimed to detect the gyrA mutations in the clinical strains of nalidixic acid and ciprofloxacin resistant K. pneumoniae isolated from the patients with urinary tract infections.
Methods: Bacterial strains...
The formation of a protective biofilm by Pseudomonas aeruginosa (PA) is one of the hallmarks of their survival both in vivo and in harsh environmental conditions, thus, biofilm-eradication has relevance from therapeutic perspectives and for infection control. The aim of our study was to investigate the possible relationship between antibiotic resis...
In this review, we evaluated several studies in the literature to analyze the benefits and deleterious effects of the use of monoclonal antibodies (MABs)-based proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors in patients with hypercholesterolemia. Increased low-density lipoprotein cholesterol (LDL-C) levels lead to an increase in th...
Background
Insulin resistance as a major problem is associated with type 2 diabetes mellitus. This study investigated the effect of Eryngium billardierei on insulin-resistance induced HepG2 cells.
Methods and results
MTT method was used to evaluate the viability of HepG2 cells treated with various doses of E. billardierei extract. An insulin-resis...
Interleukins (ILs)-which are important members of cytokines-consist of a vast group of molecules, including a wide range of immune mediators that contribute to the immunological responses of many cells and tissues. ILs are immune-glycoproteins, which directly contribute to the growth, activation, adhesion, differentiation, migration, proliferation,...
Background and Aim: Urolithiasis, with different types of stones, is known as a considerable concern regarding urinary tract. Indeed, urolithiasis is a multifactorial disease with a wide range of risk factors which predisposes patients to it. Because of the importance of urolithiasis around the world and the considerable costs for patients and publ...
Background and Objective: Klebsiella pneumoniae is one of the three pathogens that has become a global disease control and treatment problem due to its resistance to common antibiotics. For this reason, it is crucial to study the genes that cause antibiotic resistance in it. Therefore, the aim of this study was to investigate the phenotypic and gen...
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RSCB PDB) provides a wide range of digital data regarding biology and biomedicine. This huge internet resource involves a wide range of important biological data, obtained from experiments around the globe by different scientists. The Worldwide Protein Data Bank (wwPDB) rep...
Background
Klebsiella pneumoniae is armed with a wide range of antibiotic resistance mechanisms which mostly challenges effective treatment. Due to this fact, the aims of the current study were to identify the clinical strains of K. pneumoniae as well as to determine their phenotypes and molecular characterization related to antimicrobial resistanc...
Background and Aim: SARS-CoV-2 was identified in late 2019 as a respiratory disease agent called COVID-19. Several drug therapies have been studied to treat COVID-19, none of which have had a definite effect so far. In mild cases of the disease, treatment is careful to reduce the symptoms of the disease, and in severe cases, the patient must be hos...
Scientific writing is an important skill in both academia and clinical practice. The skills for writing a strong scientific paper are necessary for researchers (comprising academic staff and health-care professionals). The process of a scientific research will be completed by reporting the obtained results in the form of a strong scholarly publicat...
Human interleukins (ILs) are a collection of different biological molecules belonging to the group of cytokines, associated with various immune and non-immune systems and different signaling pathways. ILs contribute to the function of different tissues, organs and systems in the human body. They are involved in homeostasis, infectious diseases, aut...
Background/aim:
Toll-like receptors (TLRs) are pivotal biomolecules in the immune system. Today, we are all aware of the importance of TLRs in bridging innate and adaptive immune system to each other. The TLRs are activated through binding to damage/danger-associated molecular patterns (DAMPs), microbial/microbe-associated molecular patterns (MAMP...
DNA is the most important biomolecule ever discovered. Indeed, this molecule bears genetic information from one generation to another. In this regard, DNA bases have a key role in transferring genetic information and data safely. However, there are cellular, genetic, and environmental factors that may damage the different parts of DNA molecules. Th...
Urinary bladder cancer (BCa), a high ranked and common cancer around the world is a great concern for the global public health systems. Although our knowledge has been significantly raised up relating to BCa, it is not the same as other types of well-known cancers including breast and prostate cancers. Despite the use of several scientific discipline...
Acinetobacter baumannii is regarded as a life-threatening pathogen associated with community acquired and nosocomial infections, mainly pneumonia. The rise in the number of A. bau-mannii antibiotic-resistant strains reduces effective therapies and increases mortality. Bacterial comparative genomic studies have unraveled the innate and acquired viru...
Background Klebsiella pneumoniae is armed with a wide range of antibiotic resistance mechanisms which mostly challenges effective treatment. Due to this fact, the aims of the current study were to identify the clinical strains of K . pneumoniae as well as to determine their phenotypes and molecular characterization related to antimicrobial resistan...
Introduction
Uropathogenic Escherichia coli (UPEC) strains as the pioneer bacterial agents causing urinary tract infections (UTIs) bear a genomic pool consisting of flexible and adaptive genetic elements. Due to this fact, the aim of this survey was to find out the prevalence of mrk genes, antimicrobial resistant strains and ESBL producers among th...
Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Microorganisms maintains its standards for the high quality of its published papers. Thanks to the cooperation of our reviewers, in 2020, the median time to first decision was 15 days and the median time to publication was 34 days. The editors wou...
Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Pharmacy maintains its standards for the high quality of its published papers. Thanks to the cooperation of our reviewers, in 2020, the median time to first decision was 17 days and the median time to publication was 39 days. The editors would lik...
Pseudomonas aeruginosa is the most frequent cause of infection among non-fermenting Gram-negative bacteria, predominantly affecting immunocompromised patients, but its pathogenic role should not be disregarded in immunocompetent patients. These pathogens present a concerning therapeutic challenge to clinicians, both in community and in hospital set...
Dear Editor On July 21 (Sunday) and 23 (Tuesday) 2019, I had an opportunity to hold another workshop titled “How to write a scientific paper?” for Ph.D. students in Microbiology Department, College of Basic Sciences, Islamic Azad University, Shahr-e-Qods Branch, Tehran, Iran. I received brilliant feedback from the participants encouraging me to pub...
To have a successful publication in a peer-reviewed journal, a collection of factors and items is needed. Some of them directly and the others indirectly have important roles in scholarly publication. However, a well-designed scientific investigation together with a powerful academic English language may guarantee the publication of a manuscript. I...
Microbial pathogens including Enterobacteriaceae family members bear different antibiotic resistance genes comprising Extended-Spectrum-ß-Lactamases (ESBLs) and Metallo-ß-Lactamases (MBLs) on their chromosomes and mobile genetic elements such as plasmids and transposons. Because of the clinical concern regarding MBLs in global public healthcare sys...
Chaperone-usher fimbrial adhesins are powerful weapons against the uropathogens that allow the establishment of urinary tract infections (UTIs). As the antibiotic therapeutic strategy has become less effective in the treatment of uropathogen-related UTIs, the anti adhesive molecules active against fimbrial adhesins, key determinants of urovirulence...
Urinary tract infections (UTIs) are some of the most common infections in human medicine worldwide, recognized as an important public health concern to healthcare systems around the globe. In addition, urine specimens are one of the most frequently submitted samples for culture to the clinical microbiology laboratory, exceeding the number of most o...
Urinary tract infections (UTIs) are among the most common infections requiring medical attention worldwide. The production of biofilms is an important step in UTIs, not only from a mechanistic point of view, but this may also confer additional resistance, distinct from other aspects of multidrug resistance (MDR). A total of two hundred and fifty (n...
Severe durable changes may occur to the DNA structure caused by exogenous and endogenous risk factors initiating the process of carcinogenesis. By evidence, a large portion of malignancies have been demonstrated as being preventable. Moreover, the targeted prevention of cancer onset is possible, due to unique properties of plant bioactive compounds...
The editorial team greatly appreciates the reviewers who have dedicated their considerable time and expertise to the journal’s rigorous editorial process over the past 12 months, regardless of whether the papers are finally published or not. In 2019, a total of 756 papers were published in the journal, with a median time to first decision of 17 day...
The editorial team greatly appreciates the reviewers who have dedicated their considerable time and expertise to the journal’s rigorous editorial process over the past 12 months, regardless of whether the papers are finally published or not. In 2019, a total of 792 papers were published in the journal, with a median time to first decision of 35 day...
The editorial team greatly appreciates the reviewers who have dedicated their considerable time and expertise to the journal’s rigorous editorial process over the past 12 months, regardless of whether the papers are finally published or not. In 2019, a total of 6447 papers were published in the journal, with a median time to first decision of 16 da...