The goal of my research is to develop effective immunotherapies of cancer.
We have developed means of promoting selective induction of cancer-specific type-1 effector and memory cells using “polarized” DCs or combinatorial adjuvants to manipulate endogenous DCs and lymph nodes in vivo, and combinatorial adjuvants to condition tumors to selectively promote the entry of the vaccination-induced effector cells.
The resulting methods are being tested in phase I/II and phase II clinical trials.

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