Pavol Svorc Jr.

University of Ostrava · Department of Physiology and Pathophysiology

Objective: Respiratory alkalosis is an extremely common and complicated problem affecting virtually every organ system of which the etiology may be associated with pulmonary or cardiovascular disorders. However, few studies have addressed the day/night rhythm of the effect of hyperventilation on the cardiovascular system. As such, the aim of the pr...

General anesthesia is an established and well-known factor with a significant impact on cardiac parameters, which can be a problem in the final evaluation of changes in the individual electrophysiological myocardial parameters after various interventions. The present chapter provides a composite review of published data on electrocardiographic para...

The aim was to evaluate the current state of the autonomic nervous system (ANS) activity under general anesthesia using heart rate variability (HRV) in dependence on the light-dark (LD) cycle in healthy, sexually mature, spontaneously breathing, zoletil-anesthetized (30 mg/kg) Wistar rats of both sexes after a 4-week adaptation to an LD cycle (12 h...

Although it is generally assumed that females are not significantly more variable than males, there are studies that have demonstrated that differences may be quite large. The aim of the present in vivo study was to determine the effect of general anaesthesia on the status of acid–base balance in spontaneously breathing rats of both sexes in depend...

This investigation aimed to review the initial state of electrophysiological parameters that may predict the development of heart rhythm disorders in spontaneously-breathing pentobarbital-, ketamine-xylazine- and zoletil-anesthetized rats. These data will contribute to building a wider framework for a chronobiological perspective on the dependence...

Crohn's disease and ulcerative colitis, known together as inflammatory bowel diseases (IBDs), and celiac disease are the most common disorders affecting not only adults but also children. Both IBDs and celiac disease are associated with oxidative stress, which may play a significant role in their etiologies. Reactive oxygen species (ROS) such as su...

Pavol Svorc,1,2 Alexander Marossy,1 Pavol Svorc Jr2 1Department of Physiology, Medical Faculty, Safarik University, Kosice, Slovak Republic; 2Department of Physiology, Medical Faculty, Ostrava University, Ostrava, Czech Republic Objective: Respiratory alkalosis is an extremely common and complicated problem affecting virtually every organ system wh...

Primary objective: Studies focusing on the relationship between acid–base balance in vivo in rats and the dependence on the light–dark (LD) cycle are lacking. Research design: The aim of the study was on the chronobiological aspects of the impact of artificial ventilation on pH and blood gases in vivo in rats. Methods and procedures: The experiment...

The human, as well as most animal species on our planet, is exposed to regular periodical changes of the external enviroment, reflected in parallel changes in the physiological functions. In the present time, it is known that all cardiovascular functions show circadian dependence, not only blood pressure and heart rate, but also in electrophysiolog...