Pavlos Myrianthefs

Pavlos Myrianthefs
National and Kapodistrian University of Athens | uoa · Faculty of Nursing

Professor, MD, PhD

About

170
Publications
35,108
Reads
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4,244
Citations
Additional affiliations
June 2001 - June 2002
Northwestern Univeristy Chicago
Position
  • Research Associate

Publications

Publications (170)
Article
Full-text available
ΟBJECTIVE Comparison of the actual cost of hospitalization in a pediatric intensive care unit (ICU) and in an adult ICU with the reimbursement paid by the National Organization for the Provision of Health Services (EOPYY) to each hospital for ICU expenses. METHOD A retrospective observational study was carried out. The actual cost was estimated usi...
Article
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s Aim: To examine whether the serum melatonin levels in ICU patients are affected by light exposure in the "light" and "dark" parts of the ICU. Method: We measured serum melatonin levels of 10 ICU patients having their bed positioned in the "light part" (artificial and natural light) and "dark part" (only artificial light) of the ICU at two differe...
Article
Invasive pulmonary aspergillosis (IPA) has been recognized as a possible secondary infection complicating Coronavirus disease 2019 (COVID-19) and increasing mortality. The aim of this review was to report and summarize the available data in the literature concerning the incidence, pathophysiology, diagnosis, and treatment of COVID-19-associated pul...
Article
Introduction: Critical Illness Polyneuromyopathy (CIPNM) is an acquired axonal degeneration of motor, sensory and muscle fibers, that develops in patients admitted to the ICU for more than one week. Purpose: To highlight the epidemiological data, the main risk factors and methods for prevention and rehabilitation of patients who develop CIPNM. Mate...
Article
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Background: Evidence suggests that fluctuations of cortisol and vital signs can emerge during the course of mild Traumatic Brain Injury (mTBI). Objective: To investigate fluctuations of cortisol and vital signs during the acute phase of mTBI in hospitalised patients. Methods: 30 participants (19 patients with mTBI and 11 controls) were examined for...
Chapter
Thoracic ultrasound is a rapidly evolving method in assessing diseases of the chest and particularly in emergency conditions for the evaluation of dyspnoeic and hypoxic patients. An increased number of B-lines are an unspecific sign for an increased quantity of fluid in the lungs, resembling interstitial syndromes such as cardiogenic pulmonary oede...
Chapter
For the emergency management of cardiovascular disorders, echocardiography and thoracic ultrasound are indispensable imaging techniques at the bedside. In the intensive care environment, crucial questions, such as left and right ventricular function, valvular heart disease, volume status, aortic disease, cardiac infection, pleural effusion, pulmona...
Article
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ΟBJECTIVE To evaluate the knowledge and skills in first aid (FA), basic life support (BLS), cardiopulmonary resuscitation (CPR) and defibrillation of Greek police officers (PO). METHOD A cross-sectional anonymous survey was conducted from January 1, 2016, to December 31, 2017, using a specially designed self-completed questionnaire. The instrument,...
Chapter
Introduction: Patients at risk should be admitted to the ICU if there is room for improvement. Patients who have no room for improvement or the risk of death is either too high or too low should not be admitted to the ICU. Aim: To investigate ward patient characteristics, outcomes, and survival rates after an emergency call for evaluation by an...
Article
Background: A variety of valid pediatric pain assessment tools are used in clinical practice globally; however, none have been validated for use in the Pediatric Intensive Care Unit (PICU) in Greece. Furthermore, the association between pain behavioral responses and clinical status is unclear. Aims: To assess the reliability and validity of the...
Article
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Introduction: The Chronic Obstructive Pulmonary Disease (COPD) can affect patients' quality of life (QOL). Aim: The aim of this systematic review was to investigate the association between exercise and QOL of patients with COPD following a respiratory rehabilitation program in organized centers of respiratory rehabilitation of hospital units. Mater...
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Background Intensive care unit (ICU) patients experience two affronts to normal 24‐h rhythms: largely internal events such as medication and external factors such as light, noise and nursing interventions. Aims and objectives We investigated the impact of light variance within an ICU on 24‐h rhythmicity of three key physiological parameters: heart...
Article
The utility of periodic sonographic assessment and monitoring for early diagnosis of deep vein thrombosis (DVT) in patients hospitalized in intensive care units (ICUs) was investigated. Of 314 patients hospitalized in an ICU over a 24-mo period, 248 were examined. The first examination of the patients was carried out within the first 48 h of ICU ad...
Presentation
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Εισαγωγή: Η παροχή Βασικής Καρδιοπνευμονικής Αναζωογόνησης (ΚΑΡ.Π.Α.) συνοδεύεται από δυσμενή συμβάντα. Σκοπός: Σκοπός της συστηματικής ανασκόπησης είναι η περιγραφή των δυσμενών συμβάντων κατά τη παροχή Βασικής ΚΑΡ.Π.Α., σχετιζόμενες με το θύμα που βρίσκεται σε καρδιακή ανακοπή και τον ανανήπτη. Υλικό και Μέθοδος: Πραγματοποιήθηκε συστηματική βιβλ...
Article
Background: The accurate and reliable mortality prediction is very useful, in critical care medicine. There are various new variables proposed in the literature that could potentially increase the predictive ability for death in ICU of the new predictive scoring model. Objective: To develop and validate a new intensive care unit (ICU) mortality...
Article
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PURPOSE: To evaluate differences in the characteristics and outcomes of intensive care unit (ICU) patients over time. METHODS: We reviewed all epidemiological data, including comorbidities, types and severity of organ failure, interventions, lengths of stay and outcome, for patients from the Sepsis Occurrence in Acutely ill Patients (SOAP) study,...
Article
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A 43-year-old psychiatric patient was transferred in coma and hypercapnic respiratory failure at the emergency department. He was intubated for airway protection and transferred to the Intensive Care Unit (ICU). Abdominal X-ray revealed a radiopaque mass; a pharmacobezoar was suspected and confirmed by gastroscopy; one large in the stomach fundus a...
Article
Objectives: We aimed to investigate the accuracy of certain laboratory examinations obtained by the ABG analyzer (ROCHE AVL OMNI S) as compared to hospital central laboratory (CL). Methods: We prospectively collected data obtained from the same arterial blood sample regarding hematocrit, hemoglobin, potassium, and sodium. Results: ABG analyzer...
Article
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Catecholamines are molecules with immunomodulatory properties in health and disease. Several studies showed the effect of catecholamines when administered to restore hemodynamic stability in septic patients. This study investigates the effect of norepinephrine and dobutamine on whole blood cytokine release after ex vivo lipopolysaccharide (LPS) sti...
Conference Paper
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Background: Various sleeping problems and coping mechanisms have been presented in the bibliography by researchers in order the negative effects of shiftworking to be minimized. The aim of this study was to examine if physical activity and daily short nap are two of the strategies that could help nurses cope with sleep problems. Methods: A pilot cr...
Article
This study represents a first controlled comparison of restricted versus unrestricted sleep in both day and night sleep categories. A repeated measures study of a homogenous group of young women without sleep disorders (n=14) found that stage 1, 2, 3 and REM sleep, as well as sleep latency were not statistically different between day ad libitum sle...
Article
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Background . Prolonged immobilization, nutritional and vitamin D deficiency, and specific drug administration may lead to significant bone resorption. Methods and Patients . We prospectively evaluated critically ill patients admitted to the ICU for at least 10 days. Demographics, APACHE II, SOFA scores, length of stay (LOS), and drug administration...
Article
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Abstract OBJECTIVE: To assess the effect of body mass index on ICU outcome and on the development of ICU-acquired infection. DESIGN: A substudy of the Intensive Care Over Nations audit. SETTING: Seven hundred thirty ICUs in 84 countries. PATIENTS: All adult ICU patients admitted between May 8 and 18, 2012, except those admitted for less than 24 hou...
Conference Paper
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Background RN nurses who are routinely work rotating shifts are exposed to sleepiness which can lead to acute insomnia. Aim Aim of the study was to describe sleep characteristics in RNs working rotating shift system, and to compare night sleep, (between afternoon-morning shift) versus day sleep (after night shift). Also, to examine if RNs suffer fr...
Article
We present a case of a 67-year-old Caucasian female who was admitted to the pulmonary clinic of a general hospital in Athens with fever and respiratory symptoms. A lung biopsy was ordered because a clinical diagnosis of interstitial lung disease was suspected. The patient was then hospitalized in the intensive care unit. Because of the fact that pe...
Article
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Alcohol exposure is related to increased susceptibility to infections. We investigated the effect of acute exposure to alcohol on pro-and anti-inflammatory cytokine production in an ex-vivo model of whole blood stimulation with lipopolysacharide (LPS). Ten ml of whole blood were taken from 24 healthy volunteers (all men) aged 36.5 ± 1.4 years. Each...
Conference Paper
INTRODUCTION. Prolonged ICU immobilization along with nutritional defects, vitamin D deficiency and specific drug administration in critically ill patients may lead to osteoporosis. OBJECTIVES. The aim of the study was to evaluate the kinetic of two bone metabolism markers including N-terminal propeptides of type I procollagen (P1NP) and b-CrossLap...
Article
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The illness severity and outcome prediction scores for ICU patients were developed approximately 30 years ago. They are very important in clinical practice as they are widely used to predict the outcome, characterize the critical of illness, the degree of organ dysfunction, assess the resource use and quantify the needs of the ICU. The scoring syst...
Article
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Background: Abdominal infections are frequent causes of sepsis and septic shock in the intensive care unit (ICU) and are associated with adverse outcomes. We analyzed the characteristics, treatments and outcome of ICU patients with abdominal infections using data extracted from a one-day point prevalence study, the Extended Prevalence of Infection...
Article
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Corticosteroids have been used to treat head injuries for more than 30 years. In 1997, findings of a systematic review suggested that these drugs reduce risk of death by 1-2%. The CRASH trial--a multicentre international collaboration--aimed to confirm or refute such an effect by recruiting 20000 patients. In May, 2004, the data monitoring committe...
Article
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Global epidemiological data regarding outcomes for patients in intensive care units (ICUs) are scarce, but are important in understanding the worldwide burden of critical illness. We, therefore, did an international audit of ICU patients worldwide and assessed variations between hospitals and countries in terms of ICU mortality. 730 participating c...
Article
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Background Infections are a leading cause of death in patients with advanced cirrhosis, but there are relatively few data on the epidemiology of infection in intensive care unit (ICU) patients with cirrhosis. AimsWe used data from the Extended Prevalence of Infection in Intensive Care (EPIC) II one-day point-prevalence study to better define the ch...
Article
Although several components of the microbial wall of gram-positive bacteria and fungi possess immunostimulatory properties, their pathogenetic role remains incompletely evaluated. The purpose of this study was to assess the basic immune status of patients susceptible to infections and their capability for cytokine production after stimulation with...
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Background. Morbidity and mortality for critically ill patients with infections remains a global healthcare problem. We aimed to determine whether β-lactam antibiotic dosing in critically ill patients achieves concentrations associated with maximal activity and whether antibiotic concentrations affect patient outcome. Methods. This was a prospecti...
Article
Lung development and consequently lung volumes are affected by the duration, type and intensity of sporting. Athletes may have higher spirometric values compared to predicted which may lead to misclassification of this population and misdiagnosis during clinical evaluation. The aim of the study was to compare measured spirometric values with those...
Article
To study family satisfaction with care in an Intensive Care Unit (ICU) and its association with nursing workload estimated by the Nursing Activities Score (NAS). Few previous studies have investigated the association between workload in ICUs and family satisfaction. Family Satisfaction ICU 24 (FS ICU-24) questionnaires were distributed to 161 famil...
Article
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We investigated whether professional athletes may require higher tidal volume (T v ) during mechanical ventilation hypothesizing that they have significantly higher "normal" lung volumes compared to what was predicted and to nonathletes. Measured and predicted spirometric values were recorded in both athletes and nonathletes using a Spirovit SP-1 s...
Article
The development of health technology assessment has assumed transnational dimensions in assessing interventions in the levels of technology, of policy of individual and of population, and it is determined by both international and national organizations. Policy analysis, evidence-based medicine, health economic evaluation and the techniques of both...
Article
Introduction Polyclonal intravenous immunoglobulins (IVIGs) can modulate the host immune response. The purpose of the study was to investigate the effect of different immunoglobulin solutions on whole blood cytokine production capacity after Lipopolysaccharide (LPS) stimulation ex-vivo. Methods Peripheral heparinized blood was collected from 9 hea...
Article
Polyclonal intravenous immunoglobulins (IVIGs) can modulate the host immune response. The purpose of the study was to investigate the effect of different immunoglobulin solutions on whole blood cytokine production capacity after staphylococcal superantigen (exotoxin) B (SEB) stimulation ex-vivo.Methods Peripheral heparinized blood was collected fro...
Article
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The purpose of this study was to describe inhaled colistin pharmacokinetics in patients with ventilator-associated tracheobronchitis (VAT) due to polymyxin-only susceptible Gram-negative bacteria (GNB). Inhaled colistimethate sodium (CMS) was administered at a dose of 80 mg every 8 h for 7 days. Mini bronchoalveolar lavage (BAL) was performed befor...
Article
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Objective. We evaluated whether routine ultrasound examination may illustrate gallbladder abnormalities, including acute acalculous cholecystitis (AAC) in the intensive care unit (ICU). Patients and Methods. Ultrasound monitoring of the GB was performed by two blinded radiologists in mechanically ventilated patients irrespective of clinical and lab...
Article
Studies show that in the USA the radiation generated by computed tomography (CT) examinations causes annually 3,000 fatal cancers, while the increasing trend in its use reaches 10%, overloading the budget of society. The rapid developments in CT, with the introduction of multislice scanners, provide new applications with rapid, accurate conclusions...
Article
Cardiac troponins in serum have become the biomarkers of choice for the diagnosis of myocardial infarction. Yet, troponin can also be elevated by a multitude of causes in the absence of overt myocardial ischemia. Such nonspecific elevations are particularly common in the critically ill. This article aims to provide information on the significance o...
Article
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The mechanism of the breathing retraining effect on asthma control is not adequately based on evidence. The present study was designed to evaluate the effect of physiotherapy-based breathing retraining on asthma control and on asthma physiological indices across time. A 6-month controlled study was conducted. Adult patients with stable, mild to mod...
Article
Unilateral pulmonary edema (UPE) is an unusual manifestation of pulmonary edema that is frequently confused with other causes of unilateral alveolar and interstitial infiltrates. Until now limited data existed regarding the prevalence, cause, and outcome of patients presenting with cardiogenic UPE. The purpose of this review is to give insights int...
Article
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Methods To answer this question, the predicted Vt (Vt Pr = 6 ml/kg) was calculated as the percentage of measured (Ms) and predicted (Pr) FEV1 and FVC, and their difference (Δδ = Ms - Pr) was extracted to calculate the additional Vt (VtA) required according to measured PFTs. Values are expressed as the mean (SEM).
Article
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To determine how the patient to nurse ratio affects risk for ventilator-associated pneumonia. Data from an earlier study in 27 intensive care units in 9 European countries were examined in a secondary analysis. The initial cohort included 2585 consecutive patients who had mechanical ventilation (1) after admission for treatment of pneumonia or (2)...